Publications

Cancer chemotherapy and pharmacology

The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

01-01-1994

Annals of oncology : official journal of the European Society for Medical Oncology

Etoposide, leucovorin, 5-fluorouracil (ELF) combination chemotherapy for advanced gastric cancer: experience with two treatment schedules incorporating intravenous or oral etoposide.

01-01-1994

Cancer chemotherapy and pharmacology

Lithium pharmacokinetics during cisplatin-based chemotherapy: a case report.

01-01-1994

Investigational new drugs

Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

01-01-1994

Cancer chemotherapy and pharmacology

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.

01-01-1994

Pharmacy world & science : PWS

Signal transduction pathways: new targets in oncology.

17-12-1993

Journal of pharmaceutical and biomedical analysis

Chemical stability of the new antitumour agent intoplicine in infusion fluids.

01-11-1993

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

01-11-1993

Anticancer research

Clinical pharmacokinetics and pharmacodynamics of anticancer agents in pediatric patients (review).

01-09-1993

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of the cardioprotective agent ICRF-187 in infusion fluids.

01-07-1993

Investigational new drugs

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinorelbine in mice as determined by high performance liquid chromatography.

01-05-1993

Cancer research

Plasma pharmacokinetics of vinblastine and the investigational Vinca alkaloid N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate in mice as determined by high-performance liquid chromatography.

01-05-1993

Cancer chemotherapy and pharmacology

Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.

01-01-1993

European journal of cancer (Oxford, England : 1990)

Reconstitution of recombinant interleukin-2 (rIL-2): a comparative study of various rIL-2 muteins.

01-01-1993

Anticancer research

Pharmacology, bio-analysis and pharmacokinetics of the vinca alkaloids and semi-synthetic derivatives (review).

01-09-1992

Pharmaceutisch weekblad. Scientific edition

New cytotoxic drugs and targets in oncology.

21-08-1992

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of two sterile, parenteral formulations of cyclophosphamide (Endoxan) after reconstitution and dilution in commonly used infusion fluids.

01-07-1992

British journal of cancer

A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects.

01-05-1992

Journal of chromatography

Bioanalysis of the investigational anti-tumour drug 5,10-dideaza-5,6,7,8-tetrahydrofolic acid by high-performance liquid chromatography with ultraviolet detection.

15-04-1992

The Annals of pharmacotherapy

Effect of cisplatin-containing chemotherapy on lithium serum concentrations.

01-04-1992

Journal of chromatography

Biodetermination of N-(deacetyl-O-4-vinblastoyl-23)-L-tryptophan, a metabolite of vintriptol, by high-performance liquid chromatography with fluorescence detection.

14-02-1992

Journal of chromatography

Bio-analysis of vinorelbine by high-performance liquid chromatography with fluorescence detection.

17-01-1992

Journal of chromatography

High-performance liquid chromatographic determination of vinblastine, 4-O-deacetylvinblastine and the potential metabolite 4-O-deacetylvinblastine-3-oic acid in biological fluids.

16-08-1991

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical and physical stability of etoposide and teniposide in commonly used infusion fluids.

01-03-1991

Journal of pharmaceutical and biomedical analysis

Analytical methods for the determination of vinca alkaloids in biological specimens: a survey of the literature.

01-01-1991

Journal of pharmaceutical and biomedical analysis

HPLC determination of doxorubicin, doxorubicinol and four aglycone metabolites in plasma of AIDS patients.

01-01-1991

European journal of cancer (Oxford, England : 1990)

Phase I study of vintriptol, a tryptophan ester of vinblastine.

01-01-1991

Journal of pharmaceutical and biomedical analysis

Gas chromatographic analysis, with electron capture detection, of the antifungal drug fluconazole in microvolumes of human plasma.

01-01-1991

DICP : the annals of pharmacotherapy

Chemical stability of suramin in commonly used infusion fluids.

01-11-1990

Journal of parenteral science and technology : a publication of the Parenteral Drug Association

Chemical stability of the antitumor drug mitomycin C in solutions for intravesical instillation.

01-11-1990

Journal of chromatography

High-performance liquid chromatographic bio-analysis and preliminary pharmacokinetics of the experimental antitumour drug vintriptol.

03-08-1990

Journal of chromatography

High-performance liquid chromatographic method for the analysis of 10-ethyl-10-deaza-aminopterin and metabolites in plasma.

13-07-1990

Journal of pharmaceutical and biomedical analysis

Gas chromatographic analysis, with nitrogen detection, of tocainide in plasma.

01-01-1990

Journal of pharmaceutical and biomedical analysis

Bio-analysis of N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate, methane sulphonate (VileE) by high-performance liquid chromatography with fluorescence detection.

01-01-1990

Journal of chromatography

Stable and sensitive method for the simultaneous determination of N5-methyltetrahydrofolate, leucovorin, methotrexate and 7-hydroxymethotrexate in biological fluids.

24-03-1989

Journal of pharmaceutical and biomedical analysis

High-performance liquid chromatographic bioanalysis of anthracycline cytostatic drugs.

01-01-1988

The pharmacokinetics of reduced folates after intraperitoneal and intravenous administration of racemic [6S,R]-folinic acid.

Etoposide, leucovorin, 5-fluorouracil (ELF) combination chemotherapy for advanced gastric cancer: experience with two treatment schedules incorporating intravenous or oral etoposide.

Lithium pharmacokinetics during cisplatin-based chemotherapy: a case report.

Pharmaceutical development of a parenteral formulation of the novel anti-tumor agent carzelesin (U-80,244).

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinleucinol in mice as determined by high-performance liquid chromatography.

Signal transduction pathways: new targets in oncology.

Chemical stability of the new antitumour agent intoplicine in infusion fluids.

Pharmacokinetics of paclitaxel and metabolites in a randomized comparative study in platinum-pretreated ovarian cancer patients.

Clinical pharmacokinetics and pharmacodynamics of anticancer agents in pediatric patients (review).

Chemical stability of the cardioprotective agent ICRF-187 in infusion fluids.

Plasma pharmacokinetics, tissue disposition, excretion and metabolism of vinorelbine in mice as determined by high performance liquid chromatography.

Plasma pharmacokinetics of vinblastine and the investigational Vinca alkaloid N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate in mice as determined by high-performance liquid chromatography.

Tissue disposition, excretion and metabolism of vinblastine in mice as determined by high-performance liquid chromatography.

Reconstitution of recombinant interleukin-2 (rIL-2): a comparative study of various rIL-2 muteins.

Pharmacology, bio-analysis and pharmacokinetics of the vinca alkaloids and semi-synthetic derivatives (review).

New cytotoxic drugs and targets in oncology.

Chemical stability of two sterile, parenteral formulations of cyclophosphamide (Endoxan) after reconstitution and dilution in commonly used infusion fluids.

A phase I study of prolonged continuous infusion of low dose recombinant interleukin-2 in melanoma and renal cell cancer. Part I: Clinical aspects.

Bioanalysis of the investigational anti-tumour drug 5,10-dideaza-5,6,7,8-tetrahydrofolic acid by high-performance liquid chromatography with ultraviolet detection.

Effect of cisplatin-containing chemotherapy on lithium serum concentrations.

Biodetermination of N-(deacetyl-O-4-vinblastoyl-23)-L-tryptophan, a metabolite of vintriptol, by high-performance liquid chromatography with fluorescence detection.

Bio-analysis of vinorelbine by high-performance liquid chromatography with fluorescence detection.

High-performance liquid chromatographic determination of vinblastine, 4-O-deacetylvinblastine and the potential metabolite 4-O-deacetylvinblastine-3-oic acid in biological fluids.

Chemical and physical stability of etoposide and teniposide in commonly used infusion fluids.

Analytical methods for the determination of vinca alkaloids in biological specimens: a survey of the literature.

HPLC determination of doxorubicin, doxorubicinol and four aglycone metabolites in plasma of AIDS patients.

Phase I study of vintriptol, a tryptophan ester of vinblastine.

Gas chromatographic analysis, with electron capture detection, of the antifungal drug fluconazole in microvolumes of human plasma.

Chemical stability of suramin in commonly used infusion fluids.

Chemical stability of the antitumor drug mitomycin C in solutions for intravesical instillation.

High-performance liquid chromatographic bio-analysis and preliminary pharmacokinetics of the experimental antitumour drug vintriptol.

High-performance liquid chromatographic method for the analysis of 10-ethyl-10-deaza-aminopterin and metabolites in plasma.

Gas chromatographic analysis, with nitrogen detection, of tocainide in plasma.

Bio-analysis of N-(deacetyl-O-4-vinblastoyl-23)-L-ethyl isoleucinate, methane sulphonate (VileE) by high-performance liquid chromatography with fluorescence detection.

Stable and sensitive method for the simultaneous determination of N5-methyltetrahydrofolate, leucovorin, methotrexate and 7-hydroxymethotrexate in biological fluids.

High-performance liquid chromatographic bioanalysis of anthracycline cytostatic drugs.

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