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Benjamin's path into science

Read about Benjamin's journey, and find out how walks with his dad, studying history of art, and attending an incisive journal club all shaped his interests.

Read this INTERVIEW WITH BENJAMIN.

Wellcome Award to Benjamin & colleagues

Together with the labs of Daniel Panne and Matthias Merkenschlager, we were awarded a Wellcome Discovery Award. Looking forward to discovering great things together!

Read about THIS GRANT.

Klaudia receives BIF fellowship

Klaudia was awarded a competitive fellowship from the Boehringer Ingelheim Fonds that will fund her research for two years. Well done Klaudia!

Read the INTERVIEW with KLAUDIA.

KWF grant awarded to Beccy and Benjamin

We were awarded a grant from the KWF to investigate what happens when condensin II is left unchained.

Read about THIS GRANT (in Dutch). 

Switching on condensin

In an amazing three-way collaboration with the Vannini and Musacchio labs, we uncover the molecular switch that triggers chromosome condensation at mitotic onset.

Check out OUR PREPRINT.

Shaping genomes with SMC motors

Benjamin and colleagues propose a mechanism for how SMC molecular motors fold our DNA into loops. 

Read OUR PAPER, the STORY BEHIND IT and view OUR MOVIE on YouTube.

EU-LIFE highlights our story

The European alliance of leading life science research centres (EU-LIFE) writes about the beauty and impact of fundamental research. They present 15 European narratives. 

Read OUR STORY

Benjamin is appointed professor

Benjamin has been appointed Professor of Genome Biology at Delft University of Technology. 

Read our PRESS RELEASE.

Marjon becomes Dr. van Ruiten

Marjon successfully defended her PhD thesis. We are all very proud. Congrats Marjon!

Read about MARJON'S THESIS.

We're on the NSMB cover!

These lovely cubs obviously symbolize the two sister chromatids of a chromosome. Find out who symbolizes their protector SGO1 on this incredible cover of Nature Structural & Molecular Biology.

View THE COVER and read OUR PAPER.

Read about us in NRC

Two Dutch labs simultaneously made important discoveries on how cohesin controls the genome. A leading national newspaper took note. Read about our discoveries and about those of our colleagues in Delft.

Read the ARTICLE IN NRC (in Dutch).

X-file cracked: mini-key determines DNA shape

In a fantastic collaboration with Daniel Panne's lab, we discovered how a molecular code embedded in our proteins determines the shape of our DNA. 

Read THIS PAPER and our PRESS RELEASE.

How tiny rings rule the code of life

When he was a kid, Benjamin figured out what made his alarm clock tick. Now his lab studies the most beautiful mechanism of all: The secret of life itself.

Read this INTERVIEW WITH BENJAMIN.

We're on the NSMB cover!

Read how Marjon cycled up the Alpe d'Huez mountain for fundraising, and how with that same bike she then made it onto the cover of Nature Structural & Molecular Biology!  

Read the INTERVIEW WITH MARJON, read OUR PAPER, and check out this NSMB ISSUE.

Two ways to fold DNA into nuclei

Read the amazing story of how once separate research lines merged into a collaborative effort, with researchers spanning disciplines and continents.  

Read about us at BAYLOR and NKI.

Establishing nuclear architecture

We published our paper in Science on how mitotic condensin II determines chromosome-scale nuclear architecture of the subsequent interphase.

Read THIS PAPER and our PRESS RELEASE.

Vici grant awarded to Benjamin

Benjamin was awarded a 1.5 million Euro Vici grant from the NWO to study the mechanisms that shape the genome. 

Read about the AWARDED GRANT.

Anchoring loops by CTCF

We published our paper in Nature on how the interaction between CTCF and cohesin folds the genome into loops.

Read the PRESS RELEASE and OUR PAPER.

KWF grant awarded to Benjamin

Benjamin was awarded a grant from the KWF to investigate the role of a conserved domain of cohesin in genome regulation.

Check out the AWARDED GRANTS.

Claire receives BIF fellowship

Claire was awarded a competitive fellowship from the Boehringer Ingelheim Fonds that will fund her for two years. We are proud, also because Marjon received this same fellowship 18 months ago.

Read the INTERVIEW WITH CLAIRE.

KWF grant to Judith and Benjamin

We were awarded a grant from the KWF to study the role of SWI/SNF chromatin remodellers in cohesin regulation.

Read about THIS GRANT (in Dutch).

Chromosomes for dummies

Benjamin gave a lecture for the layman on cell division and chromosomes. If you are not a scientist, but do want to understand our research, then watch this lecture on YouTube.

Watch BENJAMIN'S LECTURE (in Dutch).

ERC Consolidator Grant awarded to Benjamin

Benjamin was awarded a prestigious ERC Consolidator Grant to investigate the mechanism by which cohesin structures interphase chromosomes.

Read the INTERVIEW WITH BENJAMIN.

Benjamin in 'de Volkskrant'

Researchers from Delft and Heidelberg catch condensin in the act. They reveal that condensin shapes DNA by extruding loops. Benjamin comments on this important work in a leading national newspaper.

Read THIS ARTICLE (in Dutch).

Judith wins the Antoni van Leeuwenhoek prize

Judith has won the Antoni van Leeuwenhoek Award for her fundamental discoveries in chromosome biology. This coveted prize is awarded to the most talented postdoc or PhD student of the year.

Read the INTERVIEW WITH JUDITH.

Building loops by cohesin

We published our paper in Cell on how cohesin builds loops. We tested a famous model proposed back in 2001. The mechanism that we describe is likely to shape the genomes of all life on earth.

Read the PRESS RELEASE and OUR PAPER.

Our first cover story!

This beautiful gate symbolizes cohesin's DNA exit gate, which hinges at one side, and opens at the other side. The regulation of this latter interface determines many aspects of chromosome biology.

Read OUR PAPER and view OUR COVER

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