NKI researchers unravel mechanism by which DNA forms loops


Each tiny cell in our body contains 2 meters of DNA. For this to fit, the DNA needs to be very tightly packed. It is crucial that this is done in such a way that the DNA can properly function. A team of researchers from the Netherlands Cancer Institute has uncovered the basic principles driving an important packing-mechanism: the formation of loops. Their work was published in Cell on May 4th.

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