Publications

Nature genetics

Mapping of genetic and epigenetic regulatory networks using microarrays.

European journal of cancer (Oxford, England : 1990)

Increased risk of breast cancer development after diagnosis of salivary gland tumour.

Investigational new drugs

Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.

Therapeutic drug monitoring

Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).

Biomedical chromatography : BMC

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry.

Proceedings of the National Academy of Sciences of the United States of America

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

24-05-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer.

20-05-2005

Proceedings of the National Academy of Sciences of the United States of America

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

17-05-2005

American journal of epidemiology

Validity of self-reported causes of subfertility.

15-05-2005

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology

Whole-genome views of chromatin structure.

04-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

Cancer chemotherapy and pharmacology

Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma.

Journal of pharmaceutical sciences

Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent.

Drug metabolism and disposition: the biological fate of chemicals

Transport of anthelmintic benzimidazole drugs by breast cancer resistance protein (BCRP/ABCG2).

Molecular pharmacology

Sex-dependent expression and activity of the ATP-binding cassette transporter breast cancer resistance protein (BCRP/ABCG2) in liver.

Cancer chemotherapy and pharmacology

Significant induction of cyclophosphamide and thiotepa metabolism by phenytoin.

Pharmacological research

Hepatotoxicity and metabolism of trabectedin: a literature review.

Molecular pharmacology

The breast cancer resistance protein (BCRP/ABCG2) affects pharmacokinetics, hepatobiliary excretion, and milk secretion of the antibiotic nitrofurantoin.

Oncogene

Getting in and out of mitosis with Polo-like kinase-1.

18-04-2005

American journal of pharmacogenomics : genomics-related research in drug development and clinical practice

Detection of single nucleotide polymorphisms in the ABCG2 gene in a Dutch population.

09-04-2005

Medical physics

Respiratory correlated cone beam CT.

01-04-2005

Cancer research

The effect of Bcrp1 (Abcg2) on the in vivo pharmacokinetics and brain penetration of imatinib mesylate (Gleevec): implications for the use of breast cancer resistance protein and P-glycoprotein inhibitors to enable the brain penetration of imatinib in patients.

01-04-2005

Genes & development

Mouse models for human lung cancer.

15-03-2005

Molecular and cellular biology

Uncoupling anaphase-promoting complex/cyclosome activity from spindle assembly checkpoint control by deregulating polo-like kinase 1.

Journal of cell science

Keratinocytes display normal proliferation, survival and differentiation in conditional beta4-integrin knockout mice.

Anti-cancer drugs

Effects of co-medicated drugs on cyclophosphamide bioactivation in human liver microsomes.

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Compatibility and stability of the novel anti-cancer agent C1311 in infusion devices and its in vitro biocompatibility.

Cancer chemotherapy and pharmacology

Phase I study of an oral formulation of irinotecan administered daily for 14 days every 3 weeks in patients with advanced solid tumours.

British journal of clinical pharmacology

Population pharmacokinetics of orally administered paclitaxel formulated in Cremophor EL.

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase I clinical and pharmacokinetic study of kahalalide F in patients with advanced androgen refractory prostate cancer.

The British journal of dermatology

Predictions of skin cancer incidence in the Netherlands up to 2015.

Genes & development

Frat is dispensable for canonical Wnt signaling in mammals.

15-02-2005

Hereditary cancer in clinical practice

Withdrawal from genetic counselling for cancer.

15-02-2005

Molecular cell

The deubiquitinating enzyme USP1 regulates the Fanconi anemia pathway.

04-02-2005

European journal of cancer (Oxford, England : 1990)

Normal values of serum S-100B predict prolonged survival for stage IV melanoma patients.

Genes & development

PR72, a novel regulator of Wnt signaling required for Naked cuticle function.

Nature medicine

The breast cancer resistance protein BCRP (ABCG2) concentrates drugs and carcinogenic xenotoxins into milk.

Gastroenterology

Screening behavior of individuals at high risk for colorectal cancer.

Cancer research

Comparative genomic hybridization profiles in human BRCA1 and BRCA2 breast tumors highlight differential sets of genomic aberrations.

Nature cell biology

FoxM1 is required for execution of the mitotic programme and chromosome stability.