Publications

Cancer discovery

Germline-Somatic Liaison Dictates Cancer Subtypes via de novo Steroid Biosynthesis.

Communications biology

NAA60 facilitates LRRC8A- and LRRC8D-mediated platinum drug uptake.

Research square

Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.

ESMO open

Minimum standards of specialist adolescent and young adult (AYA) cancer care units: recommendations and implementation roadmap.

European radiology

Detection rates for prostate cancer using PI-RADS 2.1 upgrading rules in transition zone lesions align with risk assessment categories: a systematic review and meta-analysis.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Changes in bone marrow fat fraction and immune cell counts in women with cervical cancer treated with primary chemoradiotherapy.

Annals of oncology : official journal of the European Society for Medical Oncology

Health-related quality of life of patients with metastatic melanoma treated with tumor-infiltrating lymphocytes compared with ipilimumab in a randomized phase III trial.

Journal of cancer survivorship : research and practice

'There is still a part of me that would love to be the old me again', how do adolescents and young adults (AYA) experience cancer-related bodily changes: a phenomenological interview study.

The Clinical neuropsychologist

A tool for false positive rate estimation in cognitive impairment research: Handling correlated tests, small samples, and composite criteria.

Physics and imaging in radiation oncology

Apparent diffusion coefficient increases during short course radiotherapy in rectal tumours: Results from a multicentre longitudinal trial.

Journal of clinical and experimental neuropsychology

Neuropsychological sequelae of cancer and cancer therapy.

Physics and imaging in radiation oncology

Impact of post-correction validation scans on intrafraction tumour misalignment in lung stereotactic body radiotherapy.

Nature

Molecular mechanism of ultrafast transport by plasma membrane Ca²⁺-ATPases.

Nature reviews. Genetics

Predicting gene expression from DNA sequence using deep learning models.

JBMR plus

Mechanisms of dexamethasone-induced bone toxicity in developing bone: a single-cell perspective.

Applied clinical informatics

Development and Evaluation of a Web-Based Outcome Database for Advanced Melanoma with Rare BRAF Mutations.

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Clinical nodal staging to assess the risk of local recurrence after rectal cancer resection: A nationwide cross-sectional study.

European journal of cancer (Oxford, England : 1990)

A novel approach to assess the prognostic value of toxicity profiles in gastric cancer patients undergoing preoperative treatment.

International journal of cancer

Socioeconomic impact among and socioeconomic support services for adolescents and young adults with cancer: A European perspective.

Annals of oncology : official journal of the European Society for Medical Oncology

Enfortumab vedotin plus pembrolizumab in untreated locally advanced or metastatic urothelial carcinoma: 2.5-year median follow-up of the phase III EV-302/KEYNOTE-A39 trial.

Nature reviews. Nephrology

Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors.

Therapeutic drug monitoring

Stabilization of Abiraterone in Human Plasma Using the Esterase Inhibitor Bis(4-nitrophenyl) Phosphate.

Journal of the National Cancer Institute

Polygenic risk of coronary artery disease for long-term survivors of breast cancer.

Trends in cell biology

Structural insights into actin filament turnover.

European journal of radiology

Automatic prostate volume estimation in transabdominal ultrasound images.

Physics and imaging in radiation oncology

Automated target misalignment correction for cone beam computed tomography-based online adaptive radiotherapy of locally advanced lung cancer patients.

Surgical endoscopy

Back-table specimen scanning using gantry-free hybrid hSPECT/LiDAR imaging: a feasibility study during PSMA-radioguided surgery.

The Lancet regional health. Europe

5-Year conditional relative survival of adolescents and young adults with solid malignancies in the Netherlands: a population-based cohort study.

Journal of magnetic resonance imaging : JMRI

Potential Time and Recall Benefits for Adaptive AI-Based Breast Cancer MRI Screening.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Focal Boost to the Intraprostatic Tumor in External Beam Radiotherapy for Patients With Localized Prostate Cancer: 10-Year Outcomes of the FLAME Trial.

Magma (New York, N.Y.)

Beyond Gleason grading: MRI radiomics to differentiate cribriform growth from non-cribriform growth in prostate cancer men.

European journal of cancer (Oxford, England : 1990)

Targeted therapy for rare BRAF-mutated melanoma: Updated multicenter analysis and launch of a publicly accessible online outcome database.

Breast (Edinburgh, Scotland)

Prognostication and treatment predictions for estrogen receptor positive early-stage breast cancer: incorporating the 70-gene signature into the PREDICT prognostication model.

Molecular oncology

Cell-free DNA aneuploidy score as a dynamic early response marker in prostate cancer.

European journal of cancer (Oxford, England : 1990)

Total tumor volume predicts overall survival and response to induction chemotherapy in patients with colorectal cancer liver metastases: An ancillary study of the phase 3 CAIRO5 trial.

Nature methods

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

Therapeutic drug monitoring

Clinical Application of Volumetric Absorptive Microsampling for Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs.

European urology

Characterization of Patients with Lymph Node Only Metastatic Urothelial Carcinoma Treated with Nivolumab Plus Gemcitabine-Cisplatin Versus Gemcitabine-Cisplatin Alone from the CheckMate 901 Trial.

Communications medicine

Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma.

Proceedings of the National Academy of Sciences of the United States of America

CRISPR screens identify the ATPase VCP as a druggable therapeutic vulnerability in cholangiocarcinoma.

Nature communications

Reanalysis of in vivo drug synergy validation study rules out synergy in most cases.

PloS one

Association of ageing-related biomarkers with peripheral neuropathy in colorectal cancer patients up to 2 years after diagnosis.

Insights into imaging

Image-guided biopsy of breast lesions-when to use what biopsy technique.

Nucleic acids research

Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor.

Nucleic acids research

DNA polymerase kappa is the primary translesion synthesis polymerase for aldehyde ICLs.

BMJ open

Perspectives on the treatment of sequela from cancer: a qualitative interview study of primary care physiotherapists.

medRxiv : the preprint server for health sciences

Beyond BRCA deficiency: Clinical and molecular predictors of survival in patients with BRCA-deficient tubo-ovarian high-grade serous carcinoma.

iScience

A 3D genome compendium of breast cancer progression.

STAR protocols

Protocol for multiplexed transcription factor activity detection using optimized barcoded reporters and an automated computational pipeline.

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene