Publications

Aging

Alzheimer's disease as a multistage process: an analysis from a population-based cohort study.

27-02-2019

Journal of structural biology: X

West-Life: A Virtual Research Environment for structural biology.

26-02-2019

Cell reports

Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing.

19-02-2019

Neuro-oncology

Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age.

19-02-2019

The EMBO journal

Long-term expanding human airway organoids for disease modeling.

15-02-2019

Nature communications

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.

15-02-2019

PloS one

Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia.

15-02-2019

Breast cancer research : BCR

Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer.

15-02-2019

Scientific reports

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion.

14-02-2019

PloS one

SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.

13-02-2019

Insights into imaging

Response evaluation after neoadjuvant treatment for rectal cancer using modern MR imaging: a pictorial review.

13-02-2019

International journal of pharmaceutics

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice.

10-02-2019

Oncoimmunology

A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma.

07-02-2019

Cell

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

07-02-2019

Cell

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

07-02-2019

PloS one

The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor.

06-02-2019

Oncoimmunology

Batf3⁺ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.

05-02-2019

Journal of pharmaceutical and biomedical analysis

Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantification of total intracellular β-decitabine nucleotides and genomic DNA incorporated β-decitabine and 5-methyl-2'-deoxycytidine.

05-02-2019

Journal of pharmaceutical and biomedical analysis

Enzyme linked immunosorbent assay for the quantification of nivolumab and pembrolizumab in human serum and cerebrospinal fluid.

05-02-2019

Nature communications

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.

04-02-2019

Head & neck

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

01-02-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Position of a panel of international lung cancer experts on the approval decision for use of durvalumab in stage III non-small-cell lung cancer (NSCLC) by the Committee for Medicinal Products for Human Use (CHMP).

01-02-2019

Critical reviews in oncology/hematology

Corrigendum to "Imaging predictors of treatment outcomes in rectal cancer: An overview" [Crit. Rev. Oncol./Hematol. 129, (September) (2018), 153-162].

01-02-2019

Nature

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.

01-02-2019

Cancer letters

Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma.

01-02-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The acute and late toxicity results of a randomized phase II dose-escalation trial in non-small cell lung cancer (PET-boost trial).

01-02-2019

Cancer research

Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.

01-02-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.

01-02-2019

World journal of urology

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

01-02-2019

Annals of surgical oncology

Cross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes.

01-02-2019

International journal of radiation oncology, biology, physics

Tumor Trailing for Liver SBRT on the MR-Linac.

01-02-2019

ERJ open research

Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.

01-02-2019

JAMA oncology

Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

01-02-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The role of positive psychological changes in anxiety and depression of patients with ovarian tumors and their partners: an observational study from the population-based PROFILES registry.

01-02-2019

BJU international

Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations.

01-02-2019

Journal of cancer survivorship : research and practice

Financial toxicity is more than costs of care: the relationship between employment and financial toxicity in long-term cancer survivors.

01-02-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology.

01-02-2019

Journal of clinical laboratory analysis

Ultrasensitive prostate-specific antigen level as a predictor of biochemical progression after robot-assisted radical prostatectomy: Towards risk adapted follow-up.

01-02-2019

Head & neck

Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy.

01-02-2019

Journal of cancer survivorship : research and practice

Factors associated with an adverse work outcome in breast cancer survivors 5-10 years after diagnosis: a cross-sectional study.

01-02-2019

Nature

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

01-02-2019

Fertility and sterility

Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors.

01-02-2019

The British journal of oral & maxillofacial surgery

Intraoperative verification of resection margins of maxillary malignancies by cone-beam computed tomography.

01-02-2019

Life science alliance

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors.

01-02-2019

Cancer immunology, immunotherapy : CII

Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma.

01-02-2019

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation.

01-02-2019

Scientific reports

Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair.

25-01-2019

Nature communications

Shared heritability and functional enrichment across six solid cancers.

25-01-2019

JCI insight

Frequent clonal relations between metastases and non-index prostate cancer lesions.

24-01-2019

Nature communications

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.

23-01-2019

Alzheimer's disease as a multistage process: an analysis from a population-based cohort study.

West-Life: A Virtual Research Environment for structural biology.

Interactions between N-terminal Modules in MPS1 Enable Spindle Checkpoint Silencing.

Risk of benign meningioma after childhood cancer in the DCOG-LATER cohort: contributions of radiation dose, exposed cranial volume, and age.

Long-term expanding human airway organoids for disease modeling.

Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancer.

Pharmacokinetics of morphine in encephalopathic neonates treated with therapeutic hypothermia.

Imprint of parity and age at first pregnancy on the genomic landscape of subsequent breast cancer.

Intravital imaging of glioma border morphology reveals distinctive cellular dynamics and contribution to tumor cell invasion.

SLFN11 can sensitize tumor cells towards IFN-γ-mediated T cell killing.

Response evaluation after neoadjuvant treatment for rectal cancer using modern MR imaging: a pictorial review.

P-glycoprotein (MDR1/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2) limit brain accumulation of the FLT3 inhibitor quizartinib in mice.

A large pooled analysis refines gene expression-based molecular subclasses in cutaneous melanoma.

Dysfunctional CD8 T Cells Form a Proliferative, Dynamically Regulated Compartment within Human Melanoma.

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

The Apparent Diffusion Coefficient (ADC) is a useful biomarker in predicting metastatic colon cancer using the ADC-value of the primary tumor.

Batf3+ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.

Development, validation, and clinical application of a high-performance liquid chromatography-tandem mass spectrometry assay for the quantification of total intracellular β-decitabine nucleotides and genomic DNA incorporated β-decitabine and 5-methyl-2'-deoxycytidine.

Enzyme linked immunosorbent assay for the quantification of nivolumab and pembrolizumab in human serum and cerebrospinal fluid.

CDK4/6 inhibitors target SMARCA4-determined cyclin D1 deficiency in hypercalcemic small cell carcinoma of the ovary.

HLA class II expression on tumor cells and low numbers of tumor-associated macrophages predict clinical outcome in oropharyngeal cancer.

Position of a panel of international lung cancer experts on the approval decision for use of durvalumab in stage III non-small-cell lung cancer (NSCLC) by the Committee for Medicinal Products for Human Use (CHMP).

Corrigendum to "Imaging predictors of treatment outcomes in rectal cancer: An overview" [Crit. Rev. Oncol./Hematol. 129, (September) (2018), 153-162].

Tissue curvature and apicobasal mechanical tension imbalance instruct cancer morphogenesis.

Metabolic targeting synergizes with MAPK inhibition and delays drug resistance in melanoma.

The acute and late toxicity results of a randomized phase II dose-escalation trial in non-small cell lung cancer (PET-boost trial).

Radiosensitivity Is an Acquired Vulnerability of PARPi-Resistant BRCA1-Deficient Tumors.

Enhancing antitumor response by combining immune checkpoint inhibitors with chemotherapy in solid tumors.

The value of periprostatic fascia thickness and fascia preservation as prognostic factors of erectile function after nerve-sparing robot-assisted radical prostatectomy.

Cross-Sectional Study on MRI Restaging After Chemoradiotherapy and Interval to Surgery in Rectal Cancer: Influence on Short- and Long-Term Outcomes.

Tumor Trailing for Liver SBRT on the MR-Linac.

Cell-free DNA in the supernatant of pleural effusion can be used to detect driver and resistance mutations, and can guide tyrosine kinase inhibitor treatment decisions.

Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients With Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

The role of positive psychological changes in anxiety and depression of patients with ovarian tumors and their partners: an observational study from the population-based PROFILES registry.

Psychosocial impact of undergoing prostate cancer screening for men with BRCA1 or BRCA2 mutations.

Financial toxicity is more than costs of care: the relationship between employment and financial toxicity in long-term cancer survivors.

Development and validation of an UPLC-MS/MS method for the therapeutic drug monitoring of oral anti-hormonal drugs in oncology.

Ultrasensitive prostate-specific antigen level as a predictor of biochemical progression after robot-assisted radical prostatectomy: Towards risk adapted follow-up.

Ototoxicity in locally advanced head and neck cancer patients treated with induction chemotherapy followed by intermediate or high-dose cisplatin-based chemoradiotherapy.

Factors associated with an adverse work outcome in breast cancer survivors 5-10 years after diagnosis: a cross-sectional study.

Author Correction: Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

Uterine function, pregnancy complications, and pregnancy outcomes among female childhood cancer survivors.

Intraoperative verification of resection margins of maxillary malignancies by cone-beam computed tomography.

Optimized ChIP-seq method facilitates transcription factor profiling in human tumors.

Phase 1 study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell carcinoma.

Inter-observer variation of hippocampus delineation in hippocampal avoidance prophylactic cranial irradiation.

Effective CRISPR/Cas9-mediated correction of a Fanconi anemia defect by error-prone end joining or templated repair.

Shared heritability and functional enrichment across six solid cancers.

Frequent clonal relations between metastases and non-index prostate cancer lesions.

Comparative oncogenomics identifies combinations of driver genes and drug targets in BRCA1-mutated breast cancer.

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Batf3⁺ DCs and type I IFN are critical for the efficacy of neoadjuvant cancer immunotherapy.