Publications

Lancet (London, England)

Pembrolizumab versus ipilimumab for advanced melanoma: final overall survival results of a multicentre, randomised, open-label phase 3 study (KEYNOTE-006).

21-10-2017

Oncotarget

Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

20-10-2017

Annals of internal medicine

Screening for Colorectal Cancer With Fecal Immunochemical Testing With and Without Postpolypectomy Surveillance Colonoscopy: A Cost-Effectiveness Analysis.

17-10-2017

Cell reports

High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer.

17-10-2017

Nutrition and cancer

The Impact of Body Mass Index and Waist Circumference on Health-related Quality of Life Among Colorectal Cancer Survivors: Results from the PROFILES Registry.

17-10-2017

Nature

Cancer drug addiction is relayed by an ERK2-dependent phenotype switch.

12-10-2017

Cell host & microbe

Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.

11-10-2017

Nature biotechnology

Antigen receptor repertoire profiling from RNA-seq data.

11-10-2017

Science (New York, N.Y.)

Neutrophils take a round-trip.

06-10-2017

The New England journal of medicine

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

05-10-2017

Molecular pharmaceutics

Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2).

02-10-2017

Journal of the National Cancer Institute

Post-traumatic Stress as the Primary Cause for Cognitive Decline-Not the Whole Story, and Perhaps No Story at All.

01-10-2017

Human mutation

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

01-10-2017

Clinical and translational radiation oncology

A predictive model for residual disease after (chemo) radiotherapy in oropharyngeal carcinoma: Combined radiological and clinical evaluation of tumor response.

01-10-2017

Genome research

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

01-10-2017

European journal of cancer (Oxford, England : 1990)

Hormone replacement therapy after risk-reducing salpingo-oophorectomy minimises endocrine and sexual problems: A prospective study.

01-10-2017

Lung cancer (Amsterdam, Netherlands)

Outcome of radical local treatment of non-small cell lung cancer patients with synchronous oligometastases.

01-10-2017

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Heart dose associated with overall survival in locally advanced NSCLC patients treated with hypofractionated chemoradiotherapy.

01-10-2017

European journal of immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

01-10-2017

Annals of oncology : official journal of the European Society for Medical Oncology

Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study.

01-10-2017

The journal of sexual medicine

Factors Associated With Specific Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Sexual Dysfunctions in Breast Cancer Survivors: A Study of Patients and Their Partners.

01-10-2017

Molecular & cellular proteomics : MCP

Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.

01-10-2017

EMBO molecular medicine

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

01-10-2017

Diseases of the colon and rectum

Quality of Life in Rectal Cancer Patients After Chemoradiation: Watch-and-Wait Policy Versus Standard Resection - A Matched-Controlled Study.

01-10-2017

Annals of surgical oncology

Adherence to Guidelines for Adult (Non-GIST) Soft Tissue Sarcoma in the Netherlands: A Plea for Dedicated Sarcoma Centers.

01-10-2017

Investigational new drugs

Pharmacokinetics and excretion of ¹⁴C-Plitidepsin in patients with advanced cancer.

01-10-2017

Magnetic resonance imaging

Towards intrinsic R2* imaging in the prostate at 3 and 7tesla.

01-10-2017

Journal of biomedical optics

Diffuse reflectance spectroscopy as a tool for real-time tissue assessment during colorectal cancer surgery.

01-10-2017

European urology

Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy.

01-10-2017

The British journal of dermatology

Histological diagnosis of basal cell carcinoma is not associated with life expectancy in elderly Dutch people: a population-based cohort study.

01-10-2017

The pharmacogenomics journal

Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies.

01-10-2017

The oncologist

Fixed Dosing of Monoclonal Antibodies in Oncology.

01-10-2017

Annals of oncology : official journal of the European Society for Medical Oncology

An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG).

01-10-2017

European journal of radiology

Value of DCE-MRI for staging and response evaluation in rectal cancer: A systematic review.

01-10-2017

Disability and rehabilitation

Cancer survivors' perspectives and experiences regarding behavioral determinants of return to work and continuation of work.

01-10-2017

European radiology

Diffusion-weighted MRI to assess response to chemoradiotherapy in rectal cancer: main interpretation pitfalls and their use for teaching.

01-10-2017

Contemporary clinical trials

Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: Alternative versus standard stimulation protocols; the study protocol of the STIM-trial.

01-10-2017

Head & neck

Efficacy of a novel swallowing exercise program for chronic dysphagia in long-term head and neck cancer survivors.

01-10-2017

Ecancermedicalscience

Responsible pricing in value-based assessment of cancer drugs: real-world data are an inevitable addition to select meaningful new cancer treatments.

29-09-2017

JMIR cancer

The Impact of Participation in Online Cancer Communities on Patient Reported Outcomes: Systematic Review.

28-09-2017

NPJ breast cancer

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

28-09-2017

Oncotarget

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

26-09-2017

Oncotarget

TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines.

22-09-2017

Oncotarget

Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.

22-09-2017

Cell chemical biology

Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery.

21-09-2017

Physics in medicine and biology

Beyond the margin recipe: the probability of correct target dosage and tumor control in the presence of a dose limiting structure.

20-09-2017

Oncoimmunology

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.

19-09-2017

Cell reports

Cohesin Can Remain Associated with Chromosomes during DNA Replication.

19-09-2017

BMC cancer

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter study.

15-09-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

15-09-2017