Publications

Journal of pharmaceutical and biomedical analysis

Simultaneous quantification of dabrafenib and trametinib in human plasma using high-performance liquid chromatography-tandem mass spectrometry.

05-06-2016

Nucleic acids research

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis.

02-06-2016

Nature

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

02-06-2016

Investigational new drugs

Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.

01-06-2016

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Feasibility and impact of a dedicated multidisciplinary rehabilitation program on health-related quality of life in advanced head and neck cancer patients.

01-06-2016

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Prospectively measured lifestyle factors and BMI explain differences in health-related quality of life between colorectal cancer patients with and without comorbid diabetes.

01-06-2016

Journal of genetic counseling

Communication Between Breast Cancer Patients Who Received Inconclusive Genetic Test Results and Their Daughters and Sisters Years After Testing.

01-06-2016

Clinical & experimental metastasis

Adhesion molecules in peritoneal dissemination: function, prognostic relevance and therapeutic options.

01-06-2016

Urologic oncology

Baseline tumor volume in assessing prognosis of patients with intermediate-risk synchronous metastatic renal cell carcinoma.

01-06-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

MRI-guided prostate adaptive radiotherapy - A systematic review.

01-06-2016

Psycho-oncology

Patients are dissatisfied with information provision: perceived information provision and quality of life in prostate cancer patients.

01-06-2016

International journal of radiation oncology, biology, physics

Intrafraction Motion in Stereotactic Body Radiation Therapy for Non-Small Cell Lung Cancer: Intensity Modulated Radiation Therapy Versus Volumetric Modulated Arc Therapy.

01-06-2016

Journal of pharmacokinetics and pharmacodynamics

The performance of model-based versus rule-based phase I clinical trials in oncology : A quantitative comparison of the performance of model-based versus rule-based phase I trials with molecularly targeted anticancer drugs over the last 2 years.

01-06-2016

Cardiovascular research

Intracellular tortuosity underlies slow cAMP diffusion in adult ventricular myocytes.

01-06-2016

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Decisions on Further Research for Predictive Biomarkers of High-Dose Alkylating Chemotherapy in Triple-Negative Breast Cancer: A Value of Information Analysis.

01-06-2016

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Treatment outcome of supraglottoplasty vs. wait-and-see policy in patients with laryngomalacia.

01-06-2016

Frontiers in bioscience (Landmark edition)

Invadosomes - shaping actin networks to follow mechanical cues.

01-06-2016

International journal of radiation oncology, biology, physics

Late Side Effects After Image Guided Intensity Modulated Radiation Therapy Compared to 3D-Conformal Radiation Therapy for Prostate Cancer: Results From 2 Prospective Cohorts.

01-06-2016

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Chemotherapy-induced neuropathy in multiple myeloma: influence on quality of life and development of a questionnaire to compose common toxicity criteria grading for use in daily clinical practice.

01-06-2016

Biochimica et biophysica acta

Beyond ion-conduction: Channel-dependent and -independent roles of TRP channels during development and tissue homeostasis.

01-06-2016

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery

Hearing loss in survivors of childhood head and neck rhabdomyosarcoma: a long-term follow-up study.

01-06-2016

European journal of clinical pharmacology

Pharmacodynamic modeling of adverse effects of anti-cancer drug treatment.

01-06-2016

Current opinion in structural biology

Editorial overview: New constructs and expression of proteins.

01-06-2016

Nature biotechnology

CRISPR knockout screening outperforms shRNA and CRISPRi in identifying essential genes.

01-06-2016

International journal of cancer

Rs895819 in MIR27A improves the predictive value of DPYD variants to identify patients at risk of severe fluoropyrimidine-associated toxicity.

01-06-2016

International journal of colorectal disease

Nodal staging in rectal cancer: why is restaging after chemoradiation more accurate than primary nodal staging?

01-06-2016

European journal of immunology

Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy.

01-06-2016

Acta oncologica (Stockholm, Sweden)

Time trends in axilla management among early breast cancer patients: Persisting major variation in clinical practice across European centers.

01-06-2016

Gut

Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/polyps.

01-06-2016

AJR. American journal of roentgenology

Evaluation of a Hanging-Breast PET System for Primary Tumor Visualization in Patients With Stage I-III Breast Cancer: Comparison With Standard PET/CT.

01-06-2016

Nature methods

siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data.

01-06-2016

Frontiers in cellular neuroscience

ATP Released by Injured Neurons Activates Schwann Cells.

01-06-2016

Neuro-oncology

EpCAM-based flow cytometry in cerebrospinal fluid greatly improves diagnostic accuracy of leptomeningeal metastases from epithelial tumors.

01-06-2016

The British journal of radiology

Hybrid surgical guidance based on the integration of radionuclear and optical technologies.

01-06-2016

Annals of oncology : official journal of the European Society for Medical Oncology

Targeted treatment and immunotherapy in leptomeningeal metastases from melanoma.

01-06-2016

Cancer chemotherapy and pharmacology

A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine.

01-06-2016

Current opinion in structural biology

Recombinant cloning strategies for protein expression.

01-06-2016

Cancer immunology, immunotherapy : CII

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

01-06-2016

Oncotarget

mTOR pathway activation is a favorable prognostic factor in human prostate adenocarcinoma.

31-05-2016

Annual review of immunology

T Cell Fate at the Single-Cell Level.

20-05-2016

Cell chemical biology

Optotaxis: Caged Lysophosphatidic Acid Enables Optical Control of a Chemotactic Gradient.

19-05-2016

Bioconjugate chemistry

Tailoring Fluorescent Dyes To Optimize a Hybrid RGD-Tracer.

18-05-2016

Cancer research

CD27 Agonism Plus PD-1 Blockade Recapitulates CD4+ T-cell Help in Therapeutic Anticancer Vaccination.

15-05-2016

Revista espanola de medicina nuclear e imagen molecular

Hybrid radioguided occult lesion localization (hybrid ROLL) of (18)F-FDG-avid lesions using the hybrid tracer indocyanine green-(99m)Tc-nanocolloid.

14-05-2016

Oncogene

Molecular basis underlying resistance to Mps1/TTK inhibitors.

12-05-2016

Breast cancer research : BCR

The distribution of ductal carcinoma in situ (DCIS) grade in 4232 women and its impact on overdiagnosis in breast cancer screening.

10-05-2016

JMIR cancer

eHealth for Breast Cancer Survivors: Use, Feasibility and Impact of an Interactive Portal.

10-05-2016

Lancet (London, England)

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial.

07-05-2016

PloS one

RAD51B in Familial Breast Cancer.

07-05-2016

Health and quality of life outcomes

Development of an item bank for the EORTC Role Functioning Computer Adaptive Test (EORTC RF-CAT).

06-05-2016