Publications

Briefings in bioinformatics

Principal component analysis of binary genomics data.

18-01-2019

Nature communications

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

16-01-2019

Immunity

The First Shall (Be) Last: Understanding Durable T Cell Responses in Immunotherapy.

15-01-2019

PloS one

Towards an understanding of C9orf82 protein/CAAP1 function.

11-01-2019

Nature communications

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.

09-01-2019

PloS one

TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.

08-01-2019

Journal of the American Heart Association

Risk and Temporal Changes of Heart Failure Among 5-Year Childhood Cancer Survivors: a DCOG-LATER Study.

08-01-2019

Pharmaceutical research

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.

07-01-2019

Annals of work exposures and health

Diet, Physical Activity, and Daylight Exposure Patterns in Night-Shift Workers and Day Workers.

07-01-2019

JCO precision oncology

Rationale and Design of the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.

04-01-2019

American journal of human genetics

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

03-01-2019

Oral oncology

From reactive to proactive tube feeding during chemoradiotherapy for head and neck cancer: A clinical prediction model-based approach.

01-01-2019

Nature reviews. Cancer

Cytokinesis defects and cancer.

01-01-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Passion for immune checkpoint blockade in triple negative breast cancer: Comment on the IMpassion130 study.

01-01-2019

Cancer immunology research

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

01-01-2019

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling.

01-01-2019

Acta oncologica (Stockholm, Sweden)

Antineoplastic treatment with crizotinib during pregnancy: a case report.

01-01-2019

International journal of radiation oncology, biology, physics

Subgroup Survival Analysis in Stage I-II NSCLC Patients With a Central Tumor Partly Treated With Risk-Adapted SBRT.

01-01-2019

Familial cancer

The uptake of presymptomatic genetic testing in hereditary breast-ovarian cancer and Lynch syndrome: a systematic review of the literature and implications for clinical practice.

01-01-2019

European journal of cancer (Oxford, England : 1990)

An open-label, multicentre safety study of vemurafenib in patients with BRAF^V600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system.

01-01-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

SPECT/CT-guided elective nodal irradiation for head and neck cancer: Estimation of clinical benefits using NTCP models.

01-01-2019

Journal of biotechnology

Small-scale GMP production of plasmid DNA using a simplified and fully disposable production method.

01-01-2019

Nature medicine

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.

01-01-2019

Clinical and translational radiation oncology

Gross tumour delineation on computed tomography and positron emission tomography-computed tomography in oesophageal cancer: A nationwide study.

01-01-2019

Trends in cell biology

The Tubulin Detyrosination Cycle: Function and Enzymes.

01-01-2019

Journal of community genetics

Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

01-01-2019

European journal of nuclear medicine and molecular imaging

Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation.

01-01-2019

Glia

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.

01-01-2019

Human reproduction (Oxford, England)

Iatrogenic endometriosis harbors somatic cancer-driver mutations.

01-01-2019

Cancer immunology research

Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma.

01-01-2019

Cancer medicine

Overall and disease-specific survival of Hodgkin lymphoma survivors who subsequently developed gastrointestinal cancer.

01-01-2019

European journal of cancer (Oxford, England : 1990)

General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States.

01-01-2019

European journal of cancer (Oxford, England : 1990)

Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core.

01-01-2019

Journal of biomedical optics

Hyperspectral imaging for tissue classification, a way toward smart laparoscopic colorectal surgery.

01-01-2019

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The impact of margin reduction on outcome and toxicity in head and neck cancer patients treated with image-guided volumetric modulated arc therapy (VMAT).

01-01-2019

Gut

Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations.

01-01-2019

The Lancet. Haematology

Characterisation of rare haematological immune-related toxicities.

01-01-2019

Physics and imaging in radiation oncology

Prostate-specific membrane antigen positron emission tomography/computed tomography as a potential tool to assess and guide salivary gland irradiation.

01-01-2019

EBioMedicine

Molecular profiling of longitudinally observed small colorectal polyps: A cohort study.

01-01-2019

European journal of cancer (Oxford, England : 1990)

A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.

01-01-2019

Genome medicine

Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response.

28-12-2018

Disability and Rehabilitation

Structured clinical reasoning for exercise prescription in patients with comorbidity

21-12-2018

Journal of translational medicine

Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery.

19-12-2018

Nature communications

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.

17-12-2018

Oncoimmunology

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

14-12-2018

Molecular & cellular oncology

With great power comes great vulnerability.

14-12-2018

The Journal of biological chemistry

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.

14-12-2018

Cell

NKG2A, a New Kid on the Immune Checkpoint Block.

13-12-2018

Scandinavian journal of urology

Outcome of sentinel lymph node biopsy in patients with clinically non-metastatic renal cell carcinoma.

12-12-2018

Frontiers in immunology

Functional Heterogeneity of CD4⁺ Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC.

07-12-2018

Principal component analysis of binary genomics data.

Kinetic analysis of multistep USP7 mechanism shows critical role for target protein in activity.

The First Shall (Be) Last: Understanding Durable T Cell Responses in Immunotherapy.

Towards an understanding of C9orf82 protein/CAAP1 function.

BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.

TRPM7 residue S1269 mediates cAMP dependence of Ca2+ influx.

Risk and Temporal Changes of Heart Failure Among 5-Year Childhood Cancer Survivors: a DCOG-LATER Study.

Impact of Older Age on the Exposure of Paclitaxel: a Population Pharmacokinetic Study.

Diet, Physical Activity, and Daylight Exposure Patterns in Night-Shift Workers and Day Workers.

Rationale and Design of the Targeted Agent and Profiling Utilization Registry (TAPUR) Study.

Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes.

From reactive to proactive tube feeding during chemoradiotherapy for head and neck cancer: A clinical prediction model-based approach.

Cytokinesis defects and cancer.

Passion for immune checkpoint blockade in triple negative breast cancer: Comment on the IMpassion130 study.

Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors.

Validation and clinical application of an LC-MS/MS method for the quantification of everolimus using volumetric absorptive microsampling.

Antineoplastic treatment with crizotinib during pregnancy: a case report.

Subgroup Survival Analysis in Stage I-II NSCLC Patients With a Central Tumor Partly Treated With Risk-Adapted SBRT.

The uptake of presymptomatic genetic testing in hereditary breast-ovarian cancer and Lynch syndrome: a systematic review of the literature and implications for clinical practice.

An open-label, multicentre safety study of vemurafenib in patients with BRAFV600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system.

SPECT/CT-guided elective nodal irradiation for head and neck cancer: Estimation of clinical benefits using NTCP models.

Small-scale GMP production of plasmid DNA using a simplified and fully disposable production method.

Low and variable tumor reactivity of the intratumoral TCR repertoire in human cancers.

Gross tumour delineation on computed tomography and positron emission tomography-computed tomography in oesophageal cancer: A nationwide study.

The Tubulin Detyrosination Cycle: Function and Enzymes.

Clinicians' use of breast cancer risk assessment tools according to their perceived importance of breast cancer risk factors: an international survey.

Robot-assisted laparoscopic surgery using DROP-IN radioguidance: first-in-human translation.

Reactive astrocytes in multiple sclerosis impair neuronal outgrowth through TRPM7-mediated chondroitin sulfate proteoglycan production.

Iatrogenic endometriosis harbors somatic cancer-driver mutations.

Peripheral Blood TCR Repertoire Profiling May Facilitate Patient Stratification for Immunotherapy against Melanoma.

Overall and disease-specific survival of Hodgkin lymphoma survivors who subsequently developed gastrointestinal cancer.

General population normative data for the EORTC QLQ-C30 health-related quality of life questionnaire based on 15,386 persons across 13 European countries, Canada and the Unites States.

Establishing the European Norm for the health-related quality of life domains of the computer-adaptive test EORTC CAT Core.

Hyperspectral imaging for tissue classification, a way toward smart laparoscopic colorectal surgery.

The impact of margin reduction on outcome and toxicity in head and neck cancer patients treated with image-guided volumetric modulated arc therapy (VMAT).

Resection of pancreatic cancer in Europe and USA: an international large-scale study highlighting large variations.

Characterisation of rare haematological immune-related toxicities.

Prostate-specific membrane antigen positron emission tomography/computed tomography as a potential tool to assess and guide salivary gland irradiation.

Molecular profiling of longitudinally observed small colorectal polyps: A cohort study.

A cost analysis of upfront DPYD genotype-guided dose individualisation in fluoropyrimidine-based anticancer therapy.

Mechanisms of PARP inhibitor resistance in cancer and insights into the DNA damage response.

Structured clinical reasoning for exercise prescription in patients with comorbidity

Towards the use of diffuse reflectance spectroscopy for real-time in vivo detection of breast cancer during surgery.

The ASCIZ-DYNLL1 axis promotes 53BP1-dependent non-homologous end joining and PARP inhibitor sensitivity.

Assessment of PD-L1 expression across breast cancer molecular subtypes, in relation to mutation rate, BRCA1-like status, tumor-infiltrating immune cells and survival.

With great power comes great vulnerability.

Profilin binding couples chloride intracellular channel protein CLIC4 to RhoA-mDia2 signaling and filopodium formation.

NKG2A, a New Kid on the Immune Checkpoint Block.

Outcome of sentinel lymph node biopsy in patients with clinically non-metastatic renal cell carcinoma.

Functional Heterogeneity of CD4+ Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC.

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An open-label, multicentre safety study of vemurafenib in patients with BRAF^V600-mutant metastatic melanoma: final analysis and a validated prognostic scoring system.

Functional Heterogeneity of CD4⁺ Tumor-Infiltrating Lymphocytes With a Resident Memory Phenotype in NSCLC.