Publications

British journal of clinical pharmacology

Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.

01-08-2019

Oral oncology

Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer.

01-08-2019

BMJ open

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

27-07-2019

Cell

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.

25-07-2019

Blood advances

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

23-07-2019

Nederlands tijdschrift voor geneeskunde

[Care for adolescents and young adults with cancer; the role of a national platform].

23-07-2019

Cancers

Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

18-07-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

15-07-2019

Bioinformatics (Oxford, England)

PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors.

15-07-2019

Key Publication

Journal for immunotherapy of cancer

Transgenerational transfer of gene-modified T cells.

15-07-2019

The EMBO journal

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

15-07-2019

Sarcoma

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

10-07-2019

BMC cancer

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy.

03-07-2019

Psycho-oncology

Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma.

01-07-2019

British journal of cancer

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.

01-07-2019

Oncogene

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.

01-07-2019

Nature reviews. Genetics

A duty to recontact in genetics: context matters.

01-07-2019

The Lancet. Oncology

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.

01-07-2019

Nature genetics

High-throughput identification of human SNPs affecting regulatory element activity.

01-07-2019

British journal of sports medicine

Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: a meta-analysis of individual patient data.

01-07-2019

Haematologica

Molecular mechanisms of bleeding disorderassociated GFI1B^Q287* mutation and its affected pathways in megakaryocytes and platelets.

01-07-2019

The Lancet. Oncology

Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

01-07-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular Characterization of Neuroendocrine-like Bladder Cancer.

01-07-2019

Future oncology (London, England)

A Phase II, single-arm trial of neoadjuvant axitinib plus avelumab in patients with localized renal cell carcinoma who are at high risk of relapse after nephrectomy (NEOAVAX).

01-07-2019

Medical physics

Correcting geometric image distortions in slice-based 4D-MRI on the MR-linac.

01-07-2019

Journal of the National Cancer Institute

The Influence of Adjuvant Systemic Regimens on Contralateral Breast Cancer Risk and Receptor Subtype.

01-07-2019

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.

01-07-2019

Nature medicine

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

01-07-2019

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

01-07-2019

Neonatology

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

01-07-2019

Immuno-oncology technology

A user's perspective on GeoMx^TM digital spatial profiling.

01-07-2019

Annals of oncology : official journal of the European Society for Medical Oncology

Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.

01-07-2019

British journal of cancer

Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

01-07-2019

Journal of magnetic resonance imaging : JMRI

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

01-07-2019

Physics and imaging in radiation oncology

Imaging for radiation treatment planning and monitoring in prostate Cancer: Precision, personalization, individualization of therapy.

01-07-2019

Seminars in radiation oncology

Adaptive Radiotherapy for Anatomical Changes.

01-07-2019

International journal of cancer

Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.

01-07-2019

European journal of cancer (Oxford, England : 1990)

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

01-07-2019

BJU international

Gallium-68-prostate-specific membrane antigen (⁶⁸ Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer.

01-07-2019

Journal of biomedical optics

Method for coregistration of optical measurements of breast tissue with histopathology: the importance of accounting for tissue deformations.

01-07-2019

Physics and imaging in radiation oncology

Planning feasibility of extremely hypofractionated prostate radiotherapy on a 1.5 T magnetic resonance imaging guided linear accelerator.

01-07-2019

The journal of sexual medicine

The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties.

01-07-2019

Antimicrobial agents and chemotherapy

Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation.

01-07-2019

Nature structural & molecular biology

Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.

01-07-2019

Trends in cancer

Avoiding Overtreatment of Ductal Carcinoma in situ.

01-07-2019

Journal of virology

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection.

01-07-2019

Bone marrow transplantation

Tyrosine kinase inhibitor levels matter in treating chronic GVHD.

01-07-2019

Urologic oncology

Communicative aspects of decision aids for localized prostate cancer treatment - A systematic review.

01-07-2019

Clinical nuclear medicine

Minimal-Invasive Robot-Assisted Image-Guided Resection of Prostate-Specific Membrane Antigen-Positive Lymph Nodes in Recurrent Prostate Cancer.

01-07-2019

American heart journal

Smoking cessation and risk of recurrent cardiovascular events and mortality after a first manifestation of arterial disease.

01-07-2019

Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.

Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer.

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

[Care for adolescents and young adults with cancer; the role of a national platform].

Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors.

Transgenerational transfer of gene-modified T cells.

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy.

Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma.

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.

A duty to recontact in genetics: context matters.

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.

High-throughput identification of human SNPs affecting regulatory element activity.

Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: a meta-analysis of individual patient data.

Molecular mechanisms of bleeding disorderassociated GFI1BQ287* mutation and its affected pathways in megakaryocytes and platelets.

Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

Molecular Characterization of Neuroendocrine-like Bladder Cancer.

A Phase II, single-arm trial of neoadjuvant axitinib plus avelumab in patients with localized renal cell carcinoma who are at high risk of relapse after nephrectomy (NEOAVAX).

Correcting geometric image distortions in slice-based 4D-MRI on the MR-linac.

The Influence of Adjuvant Systemic Regimens on Contralateral Breast Cancer Risk and Receptor Subtype.

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

A user's perspective on GeoMxTM digital spatial profiling.

Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.

Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

Imaging for radiation treatment planning and monitoring in prostate Cancer: Precision, personalization, individualization of therapy.

Adaptive Radiotherapy for Anatomical Changes.

Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.

Gallium-68-prostate-specific membrane antigen (68 Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer.

Method for coregistration of optical measurements of breast tissue with histopathology: the importance of accounting for tissue deformations.

Planning feasibility of extremely hypofractionated prostate radiotherapy on a 1.5 T magnetic resonance imaging guided linear accelerator.

The International Index of Erectile Function (IIEF)-A Systematic Review of Measurement Properties.

Systematic Review of Host-Mediated Activity of Miltefosine in Leishmaniasis through Immunomodulation.

Crystal structure of the tubulin tyrosine carboxypeptidase complex VASH1-SVBP.

Avoiding Overtreatment of Ductal Carcinoma in situ.

A Genome-Wide Haploid Genetic Screen Identifies Heparan Sulfate-Associated Genes and the Macropinocytosis Modulator TMED10 as Factors Supporting Vaccinia Virus Infection.

Tyrosine kinase inhibitor levels matter in treating chronic GVHD.

Communicative aspects of decision aids for localized prostate cancer treatment - A systematic review.

Minimal-Invasive Robot-Assisted Image-Guided Resection of Prostate-Specific Membrane Antigen-Positive Lymph Nodes in Recurrent Prostate Cancer.

Smoking cessation and risk of recurrent cardiovascular events and mortality after a first manifestation of arterial disease.

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Molecular mechanisms of bleeding disorderassociated GFI1B^Q287* mutation and its affected pathways in megakaryocytes and platelets.

A user's perspective on GeoMx^TM digital spatial profiling.

Gallium-68-prostate-specific membrane antigen (⁶⁸ Ga-PSMA) positron emission tomography (PET)/computed tomography (CT) predicts complete biochemical response from radical prostatectomy and lymph node dissection in intermediate- and high-risk prostate cancer.

Planning feasibility of extremely hypofractionated prostate radiotherapy on a 1.5 T magnetic resonance imaging guided linear accelerator.