Publications

Breast cancer research and treatment

Intra-arterial Mitomycin C infusion in a large cohort of advanced liver metastatic breast cancer patients: safety, efficacy and factors influencing survival.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Relevance of Endoxifen Concentrations: Absence of Evidence Is Not Evidence of Absence.

JACC. Cardiovascular imaging

State-of-the-Art Deep Learning in Cardiovascular Image Analysis.

Current opinion in chemical biology

Visualizing transcription: key to understanding gene expression dynamics.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

Organ Function Preservation Failure after (Chemo)Radiotherapy in Head and Neck Cancer: A Retrospective Cohort Analysis.

European journal of nuclear medicine and molecular imaging

Lesion detection by [⁸⁹Zr]Zr-DFO-girentuximab and [¹⁸F]FDG-PET/CT in patients with newly diagnosed metastatic renal cell carcinoma.

Experimental hematology

Bmi1 restricts the adipogenic differentiation of bone marrow stromal cells to maintain the integrity of the hematopoietic stem cell niche.

Genetics in medicine : official journal of the American College of Medical Genetics

BOADICEA: a comprehensive breast cancer risk prediction model incorporating genetic and nongenetic risk factors.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Physical problems, functional limitations, and preferences for physical therapist-guided exercise programs among Dutch patients with metastatic breast cancer: a mixed methods study.

British journal of haematology

Setting up a national infrastructure for survivorship care after treatment for Hodgkin lymphoma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the novel TRK inhibitor selitrectinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

British journal of clinical pharmacology

Exposure-response modeling of tocilizumab in rheumatoid arthritis using continuous composite measures and their individual components.

Oral oncology

Laryngo-esophageal dysfunction free survival and propensity score matched analysis comparing organ preservation and total laryngectomy in hypopharynx cancer.

BMJ open

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

27-07-2019

Cell

Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold.

25-07-2019

Blood advances

Fludarabine exposure in the conditioning prior to allogeneic hematopoietic cell transplantation predicts outcomes.

23-07-2019

Nederlands tijdschrift voor geneeskunde

[Care for adolescents and young adults with cancer; the role of a national platform].

23-07-2019

Cancers

Metastatic Uveal Melanoma: Treatment Strategies and Survival-Results from the Dutch Melanoma Treatment Registry.

18-07-2019

Clinical cancer research : an official journal of the American Association for Cancer Research

EZH2 Is Overexpressed in BRCA1-like Breast Tumors and Predictive for Sensitivity to High-Dose Platinum-Based Chemotherapy.

Bioinformatics (Oxford, England)

PRECISE: a domain adaptation approach to transfer predictors of drug response from pre-clinical models to tumors.

Key Publication

Journal for immunotherapy of cancer

Transgenerational transfer of gene-modified T cells.

The EMBO journal

Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.

Sarcoma

Survival and Cost-Effectiveness of Trabectedin Compared to Ifosfamide Monotherapy in Advanced Soft Tissue Sarcoma Patients.

10-07-2019

BMC cancer

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy.

03-07-2019

Psycho-oncology

Determinants of satisfactory patient communication and shared decision making in patients with multiple myeloma.

British journal of cancer

Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.

Oncogene

Non-canonical HIF-1 stabilization contributes to intestinal tumorigenesis.

Nature reviews. Genetics

A duty to recontact in genetics: context matters.

The Lancet. Oncology

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium.

Nature genetics

High-throughput identification of human SNPs affecting regulatory element activity.

British journal of sports medicine

Effects and moderators of exercise on muscle strength, muscle function and aerobic fitness in patients with cancer: a meta-analysis of individual patient data.

Haematologica

Molecular mechanisms of bleeding disorderassociated GFI1B^Q287* mutation and its affected pathways in megakaryocytes and platelets.

The Lancet. Oncology

Identification of the optimal combination dosing schedule of neoadjuvant ipilimumab plus nivolumab in macroscopic stage III melanoma (OpACIN-neo): a multicentre, phase 2, randomised, controlled trial.

Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular Characterization of Neuroendocrine-like Bladder Cancer.

Future oncology (London, England)

A Phase II, single-arm trial of neoadjuvant axitinib plus avelumab in patients with localized renal cell carcinoma who are at high risk of relapse after nephrectomy (NEOAVAX).

Medical physics

Correcting geometric image distortions in slice-based 4D-MRI on the MR-linac.

Journal of the National Cancer Institute

The Influence of Adjuvant Systemic Regimens on Contralateral Breast Cancer Risk and Receptor Subtype.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Measuring health-related quality of life in colorectal cancer patients: systematic review of measurement properties of the EORTC QLQ-CR29.

Nature medicine

Publisher Correction: Immune induction strategies in metastatic triple-negative breast cancer to enhance the sensitivity to PD-1 blockade: the TONIC trial.

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of AJCC-8 staging in the phase III EORTC1325/KEYNOTE-054 trial of pembrolizumab vs placebo in resected high-risk stage III melanoma.

Neonatology

Phenobarbital, Midazolam Pharmacokinetics, Effectiveness, and Drug-Drug Interaction in Asphyxiated Neonates Undergoing Therapeutic Hypothermia.

Immuno-oncology technology

A user's perspective on GeoMx^TM digital spatial profiling.

Annals of oncology : official journal of the European Society for Medical Oncology

Discontinuation of anti-PD-1 antibody therapy in the absence of disease progression or treatment limiting toxicity: clinical outcomes in advanced melanoma.

British journal of cancer

Molecular tumour boards and molecular diagnostics for patients with cancer in the Netherlands: experiences, challenges, and aspirations.

Journal of magnetic resonance imaging : JMRI

Quantitative 3T multiparametric MRI of benign and malignant prostatic tissue in patients with and without local recurrent prostate cancer after external-beam radiation therapy.

Physics and imaging in radiation oncology

Imaging for radiation treatment planning and monitoring in prostate Cancer: Precision, personalization, individualization of therapy.

Seminars in radiation oncology

Adaptive Radiotherapy for Anatomical Changes.

International journal of cancer

Efficacy of anastrozole after tamoxifen in early breast cancer patients with chemotherapy-induced ovarian function failure.

European journal of cancer (Oxford, England : 1990)

Efficacy of PD-1-based immunotherapy after radiologic progression on targeted therapy in stage IV melanoma.