Publications

PloS one

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

09-07-2020

BMC cancer

Design of the PROstate cancer follow-up care in Secondary and Primary hEalth Care study (PROSPEC): a randomized controlled trial to evaluate the effectiveness of primary care-based follow-up of localized prostate cancer survivors.

08-07-2020

Journal of translational medicine

Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma.

03-07-2020

Nature communications

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

03-07-2020

Scientific reports

Epigenetic profiling demarcates molecular subtypes of muscle-invasive bladder cancer.

02-07-2020

Nature medicine

Author Correction: Caring for patients with cancer in the COVID-19 era.

01-07-2020

Molecular cancer research : MCR

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

01-07-2020

Cardiovascular and interventional radiology

Percutaneous Microwave Ablation of Histologically Proven T1 Renal Cell Carcinoma.

01-07-2020

Cancer chemotherapy and pharmacology

Correction to: Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

01-07-2020

Nature cancer

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.

01-07-2020

Nature medicine

Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.

01-07-2020

JAMA network open

Association of Image-Guided Navigation With Complete Resection Rate in Patients With Locally Advanced Primary and Recurrent Rectal Cancer: A Nonrandomized Controlled Trial.

01-07-2020

JAMA oncology

De-Escalating Breast Cancer Surgery for Low-Risk Ductal Carcinoma in Situ.

01-07-2020

Clinical pharmacokinetics

Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.

01-07-2020

Journal of cancer research and clinical oncology

Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.

01-07-2020

International journal of radiation oncology, biology, physics

Correlating Dose Variables with Local Tumor Control in Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer: A Modeling Study on 1500 Individual Treatments.

01-07-2020

Clinical pharmacology in drug development

Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.

01-07-2020

Life science alliance

Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.

01-07-2020

Learning health systems

Learning health care systems: Highly needed but challenging.

01-07-2020

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic.

01-07-2020

Familial cancer

Patient-reported burden of intensified surveillance and surgery in high-risk individuals under pancreatic cancer surveillance.

01-07-2020

Journal of the National Cancer Institute. Monographs

Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Rationale and Framework for the Monograph and Overview of Eligible Studies.

01-07-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma.

01-07-2020

SLAS discovery : advancing life sciences R & D

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

01-07-2020

Lasers in surgery and medicine

Toward assessment of resection margins using hyperspectral diffuse reflection imaging (400-1,700 nm) during tongue cancer surgery.

01-07-2020

Genetic epidemiology

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.

01-07-2020

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Healthcare professionals' perspectives of barriers and facilitators in implementing physical activity programmes delivered to cancer survivors in a shared-care model: a qualitative study.

01-07-2020

Physics and imaging in radiation oncology

Professional quality of life and burnout among medical physicists working in radiation oncology: The role of alexithymia and empathy.

01-07-2020

Journal for immunotherapy of cancer

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

01-07-2020

Clinical pharmacokinetics

Population Pharmacokinetics of MCLA-128, a HER2/HER3 Bispecific Monoclonal Antibody, in Patients with Solid Tumors.

01-07-2020

Physics and imaging in radiation oncology

Clinical workflow for treating patients with a metallic hip prosthesis using magnetic resonance imaging-guided radiotherapy.

01-07-2020

Molecular oncology

Technology-driven research for radiotherapy innovation.

01-07-2020

British journal of pharmacology

OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation.

01-07-2020

Nature medicine

Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

01-07-2020

Future oncology (London, England)

Real-world outcomes of radium-223 dichloride for metastatic castration resistant prostate cancer.

01-07-2020

Journal of the National Cancer Institute. Monographs

Evaluation of Confounding and Selection Bias in Epidemiological Studies of Populations Exposed to Low-Dose, High-Energy Photon Radiation.

01-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.

30-06-2020

Cell

Mapping the Uncharted Territories of Human Brain Malignancies.

25-06-2020

Journal of Alzheimer's disease : JAD

Association Between the Tumor Marker Carcinoembryonic Antigen and the Risk of Dementia.

23-06-2020

F1000Research

A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community).

23-06-2020

Nature communications

Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.

22-06-2020

bioRxiv

Human Prostate Cancer-Associated Macrophage Subtypes and Prognostic Potential Revealed by Single-cell Transcriptomics

20-06-2020

Key Publication

Molecular cell

Rational Cancer Treatment Combinations: An Urgent Clinical Need.

18-06-2020

Scientific reports

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.

16-06-2020

Journal of immunology (Baltimore, Md. : 1950)

GPA33: A Marker to Identify Stable Human Regulatory T Cells.

15-06-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative bioanalytical assay for the selective RET inhibitors selpercatinib and pralsetinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

15-06-2020

International journal of molecular sciences

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

12-06-2020

Blood

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization.

11-06-2020

Nature communications

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.

10-06-2020

Nature communications

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.

05-06-2020

Kinome capture sequencing of high-grade serous ovarian carcinoma reveals novel mutations in the JAK3 gene.

Design of the PROstate cancer follow-up care in Secondary and Primary hEalth Care study (PROSPEC): a randomized controlled trial to evaluate the effectiveness of primary care-based follow-up of localized prostate cancer survivors.

Presence of a 34-gene signature is a favorable prognostic marker in squamous non-small cell lung carcinoma.

Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers.

Epigenetic profiling demarcates molecular subtypes of muscle-invasive bladder cancer.

Author Correction: Caring for patients with cancer in the COVID-19 era.

The NF-κB Pathway Promotes Tamoxifen Tolerance and Disease Recurrence in Estrogen Receptor-Positive Breast Cancers.

Percutaneous Microwave Ablation of Histologically Proven T1 Renal Cell Carcinoma.

Correction to: Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

Publisher Correction: Long-distance modulation of bystander tumor cells by CD8+ T-cell-secreted IFN-γ.

Support systems to guide clinical decision-making in precision oncology: The Cancer Core Europe Molecular Tumor Board Portal.

Association of Image-Guided Navigation With Complete Resection Rate in Patients With Locally Advanced Primary and Recurrent Rectal Cancer: A Nonrandomized Controlled Trial.

De-Escalating Breast Cancer Surgery for Low-Risk Ductal Carcinoma in Situ.

Cost-Neutral Optimization of Pazopanib Exposure by Splitting Intake Moments: A Prospective Pharmacokinetic Study in Cancer Patients.

Olaparib and temozolomide in desmoplastic small round cell tumors: a promising combination in vitro and in vivo.

Correlating Dose Variables with Local Tumor Control in Stereotactic Body Radiation Therapy for Early-Stage Non-Small Cell Lung Cancer: A Modeling Study on 1500 Individual Treatments.

Stable Isotopically Labeled Intravenous Microdose Pharmacokinetic Trials as a Tool to Assess Absolute Bioavailability: Feasibility and Paradigm to Apply for Protein Kinase Inhibitors in Oncology.

Integrin α3β1 in hair bulge stem cells modulates CCN2 expression and promotes skin tumorigenesis.

Learning health care systems: Highly needed but challenging.

Treatment Guidance for Patients With Lung Cancer During the Coronavirus 2019 Pandemic.

Patient-reported burden of intensified surveillance and surgery in high-risk individuals under pancreatic cancer surveillance.

Epidemiological Studies of Low-Dose Ionizing Radiation and Cancer: Rationale and Framework for the Monograph and Overview of Eligible Studies.

Combined Therapy of AXL and HDAC Inhibition Reverses Mesenchymal Transition in Diffuse Intrinsic Pontine Glioma.

Combining Supervised and Unsupervised Machine Learning Methods for Phenotypic Functional Genomics Screening.

Toward assessment of resection margins using hyperspectral diffuse reflection imaging (400-1,700 nm) during tongue cancer surgery.

Transcriptome-wide association study of breast cancer risk by estrogen-receptor status.

Healthcare professionals' perspectives of barriers and facilitators in implementing physical activity programmes delivered to cancer survivors in a shared-care model: a qualitative study.

Professional quality of life and burnout among medical physicists working in radiation oncology: The role of alexithymia and empathy.

Fibroblast activation protein-targeted-4-1BB ligand agonist amplifies effector functions of intratumoral T cells in human cancer.

Population Pharmacokinetics of MCLA-128, a HER2/HER3 Bispecific Monoclonal Antibody, in Patients with Solid Tumors.

Clinical workflow for treating patients with a metallic hip prosthesis using magnetic resonance imaging-guided radiotherapy.

Technology-driven research for radiotherapy innovation.

OATP1A/1B, CYP3A, ABCB1, and ABCG2 limit oral availability of the NTRK inhibitor larotrectinib, while ABCB1 and ABCG2 also restrict its brain accumulation.

Author Correction: Integrative molecular and clinical modeling of clinical outcomes to PD1 blockade in patients with metastatic melanoma.

Real-world outcomes of radium-223 dichloride for metastatic castration resistant prostate cancer.

Evaluation of Confounding and Selection Bias in Epidemiological Studies of Populations Exposed to Low-Dose, High-Energy Photon Radiation.

Uncoupling DNA damage from chromatin damage to detoxify doxorubicin.

Mapping the Uncharted Territories of Human Brain Malignancies.

Association Between the Tumor Marker Carcinoembryonic Antigen and the Risk of Dementia.

A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community).

Multiple low dose therapy as an effective strategy to treat EGFR inhibitor-resistant NSCLC tumours.

Human Prostate Cancer-Associated Macrophage Subtypes and Prognostic Potential Revealed by Single-cell Transcriptomics

Rational Cancer Treatment Combinations: An Urgent Clinical Need.

Germline HOXB13 mutations p.G84E and p.R217C do not confer an increased breast cancer risk.

GPA33: A Marker to Identify Stable Human Regulatory T Cells.

Quantitative bioanalytical assay for the selective RET inhibitors selpercatinib and pralsetinib in mouse plasma and tissue homogenates using liquid chromatography-tandem mass spectrometry.

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

MKL1 deficiency results in a severe neutrophil motility defect due to impaired actin polymerization.

A cancer drug atlas enables synergistic targeting of independent drug vulnerabilities.

Partner independent fusion gene detection by multiplexed CRISPR-Cas9 enrichment and long read nanopore sequencing.

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Publisher Correction: Long-distance modulation of bystander tumor cells by CD8⁺ T-cell-secreted IFN-γ.