Publications

Cell research

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models.

01-07-2018

Anti-cancer drugs

Real-world healthcare costs of ipilimumab in patients with advanced cutaneous melanoma in The Netherlands.

01-07-2018

Cancer immunology research

Subcellular Localization of Antigen in Keratinocytes Dictates Delivery of CD4⁺ T-cell Help for the CTL Response upon Therapeutic DNA Vaccination into the Skin.

01-07-2018

Cancer prevention research (Philadelphia, Pa.)

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

01-07-2018

Neoplasia (New York, N.Y.)

Improved Brain Penetration and Antitumor Efficacy of Temozolomide by Inhibition of ABCB1 and ABCG2.

01-07-2018

Nature medicine

SHP2 is required for growth of KRAS-mutant non-small-cell lung cancer in vivo.

01-07-2018

Physics and imaging in radiation oncology

Biochemical recurrence prediction after radiotherapy for prostate cancer with T2w magnetic resonance imaging radiomic features.

01-07-2018

The European journal of health economics : HEPAC : health economics in prevention and care

Cost-utility and cost-effectiveness of physical exercise during adjuvant chemotherapy.

01-07-2018

PLoS biology

Decoding the chromatin proteome of a single genomic locus by DNA sequencing.

01-07-2018

The Lancet. Oncology

Adjuvant therapy in resectable gastric cancer-the CRITICS trial - Authors' reply.

01-07-2018

Annals of surgery

Response to: "DCIS and Breast Cancer: Challenging the Paradigm".

01-07-2018

Drug and alcohol dependence

Exploring the role of low-frequency and rare exonic variants in alcohol and tobacco use.

01-07-2018

Nature cell biology

Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis.

01-07-2018

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Tumor-infiltrating lymphocytes and ductal carcinoma in situ of the breast: friends or foes?

01-07-2018

Arteriosclerosis, thrombosis, and vascular biology

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

01-07-2018

Biochimica et biophysica acta. Molecular basis of disease

TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4.

01-07-2018

Nature genetics

A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer.

01-07-2018

Anti-cancer drugs

Real-world use, safety, and survival of ipilimumab in metastatic cutaneous melanoma in The Netherlands.

01-07-2018

Oral oncology

Clinicopathological characteristics and outcome of 31 patients with ETV6-NTRK3 fusion gene confirmed (mammary analogue) secretory carcinoma of salivary glands.

01-07-2018

Oncotarget

MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer.

29-06-2018

Cell reports

Neutrophils Kill Antibody-Opsonized Cancer Cells by Trogoptosis.

26-06-2018

Frontiers in cellular and infection microbiology

Macrophage Activation Marker Neopterin: A Candidate Biomarker for Treatment Response and Relapse in Visceral Leishmaniasis.

19-06-2018

Nederlands tijdschrift voor geneeskunde

[Ethical dilemmas in a general practitioner's clinic due to incidental findings resulting from whole genome sequencing].

15-06-2018

Nederlands tijdschrift voor geneeskunde

[Recent treatment results for metastatic melanoma: data from the Dutch Melanoma Treatment Registry].

15-06-2018

Nederlands tijdschrift voor geneeskunde

[Unsolicited genomic findings in daily clinical practice].

15-06-2018

Cancer cell

Selective Loss of PARG Restores PARylation and Counteracts PARP Inhibitor-Mediated Synthetic Lethality.

11-06-2018

International journal of pharmaceutics

Solubility and bioavailability improvement of pazopanib hydrochloride.

10-06-2018

Molecular cell

Kinetics and Fidelity of the Repair of Cas9-Induced Double-Strand DNA Breaks.

07-06-2018

Nederlands tijdschrift voor geneeskunde

[The accuracy of patients' perceptions of the risks associated with localised prostate cancer treatments].

07-06-2018

Epigenetics & chromatin

DamID profiling of dynamic Polycomb-binding sites in Drosophila imaginal disc development and tumorigenesis.

05-06-2018

Health and quality of life outcomes

Understanding the quality of life (QOL) issues in survivors of cancer: towards the development of an EORTC QOL cancer survivorship questionnaire.

04-06-2018

Chembiochem : a European journal of chemical biology

Bioorthogonally Applicable Fluorescence Deactivation Strategy for Receptor Kinetics Study and Theranostic Pretargeting Approaches.

04-06-2018

Molecular oncology

Haploid genetic screens identify genetic vulnerabilities to microtubule-targeting agents.

01-06-2018

Life science alliance

ERα activity depends on interaction and target site corecruitment with phosphorylated CREB1.

01-06-2018

British journal of clinical pharmacology

Intracellular pharmacokinetics of gemcitabine, its deaminated metabolite 2',2'-difluorodeoxyuridine and their nucleotides.

01-06-2018

American journal of clinical dermatology

Advanced Melanoma: Current Treatment Options, Biomarkers, and Future Perspectives.

01-06-2018

European journal of cancer (Oxford, England : 1990)

Corrigendum to "An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint^®)" [Eur J Cancer 75 (April 2017) 5-13].

01-06-2018

Oral oncology

Comparative genomic analysis of oral versus laryngeal and pharyngeal cancer.

01-06-2018

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Molecular Imaging of ABCB1 and ABCG2 Inhibition at the Human Blood-Brain Barrier Using Elacridar and ¹¹C-Erlotinib PET.

01-06-2018

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Retrospective self-sorted 4D-MRI for the liver.

01-06-2018

Cell research

A CRISPR screen identifies CDK7 as a therapeutic target in hepatocellular carcinoma.

01-06-2018

British journal of clinical pharmacology

Development of a nomogram for the estimation of long-term adherence to clozapine therapy using neutrophil fluorescence.

01-06-2018

Nucleic acids research

Easy quantification of template-directed CRISPR/Cas9 editing.

01-06-2018

The Journal of urology

Lymphatic Drainage from Renal Tumors In Vivo: A Prospective Sentinel Node Study Using SPECT/CT Imaging.

01-06-2018

Gynecologic oncology

Course of chemotherapy-induced peripheral neuropathy and its impact on health-related quality of life among ovarian cancer patients: A longitudinal study.

01-06-2018

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

A systematic review of the measurement properties of the Body Image Scale (BIS) in cancer patients.

01-06-2018

Investigational new drugs

ATP-binding cassette transporters limit the brain penetration of Wee1 inhibitors.

01-06-2018

Journal of pharmacokinetics and pharmacodynamics

Pharmacodynamic modeling of cardiac biomarkers in breast cancer patients treated with anthracycline and trastuzumab regimens.

01-06-2018

European journal of human genetics : EJHG

The association between cancer family history and ovarian cancer risk in BRCA1/2 mutation carriers: can it be explained by the mutation position?

01-06-2018

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Survivorship care plans have a negative impact on long-term quality of life and anxiety through more threatening illness perceptions in gynecological cancer patients: the ROGY care trial.

01-06-2018