Publications

Nature communications

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

07-08-2020

EJNMMI research

A DROP-IN beta probe for robot-assisted ⁶⁸Ga-PSMA radioguided surgery: first ex vivo technology evaluation using prostate cancer specimens.

06-08-2020

Brachytherapy

Applicator visualization using ultrashort echo time MRI for high-dose-rate endorectal brachytherapy.

05-08-2020

European journal of clinical pharmacology

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

01-08-2020

Clinical psychology review

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.

01-08-2020

Investigational new drugs

Mass balance and metabolite profiling of ¹⁴C-guadecitabine in patients with advanced cancer.

01-08-2020

Pharmacology research & perspectives

No relation between docetaxel administration route and high-grade diarrhea incidence.

01-08-2020

European journal of cancer (Oxford, England : 1990)

Adjuvant chemotherapy in small node-negative triple-negative breast cancer.

01-08-2020

Radiology

Radiogenomic Analysis of Breast Cancer by Linking MRI Phenotypes with Tumor Gene Expression.

01-08-2020

Acta oncologica (Stockholm, Sweden)

First system for fully-automated multi-criterial treatment planning for a high-magnetic field MR-Linac applied to rectal cancer.

01-08-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Updated efficacy results from the JAVELIN Renal 101 trial: first-line avelumab plus axitinib versus sunitinib in patients with advanced renal cell carcinoma.

01-08-2020

Thyroid : official journal of the American Thyroid Association

Long-Term Effects of Radioiodine Treatment on Female Fertility in Survivors of Childhood Differentiated Thyroid Carcinoma.

01-08-2020

International journal of cancer

Ascertainment of cancer in longitudinal research: The concordance between the Rotterdam Study and the Netherlands Cancer Registry.

01-08-2020

Cancer

Patterns and predictors of cancer-related fatigue in ovarian and endometrial cancers: 1-year longitudinal study.

01-08-2020

Journal for immunotherapy of cancer

Rationalizing the pathway to personalized neoadjuvant immunotherapy: the Lombard Street Approach.

01-08-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Management of early melanoma recurrence despite adjuvant anti-PD-1 antibody therapy^☆.

01-08-2020

British journal of clinical pharmacology

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

01-08-2020

Molecular oncology

Towards a cancer mission in Horizon Europe: recommendations.

01-08-2020

Journal for immunotherapy of cancer

Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.

01-08-2020

The Lancet. Oncology

100 European core quality standards for cancer care and research centres.

01-08-2020

Acta oncologica (Stockholm, Sweden)

Health-related quality of life and symptom burden of epithelioid hemangioendothelioma patients: a global patient-driven Facebook study in a very rare malignancy.

01-08-2020

European urology oncology

Distribution of Molecular Subtypes in Muscle-invasive Bladder Cancer Is Driven by Sex-specific Differences.

01-08-2020

Nature genetics

The DNA methylation landscape of advanced prostate cancer.

01-08-2020

Annals of surgical oncology

Selection of Patients for Organ Preservation After Chemoradiotherapy: MRI Identifies Poor Responders Who Can Go Straight to Surgery.

01-08-2020

Genes & development

Cells of origin of lung cancers: lessons from mouse studies.

01-08-2020

Investigational new drugs

Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).

01-08-2020

Therapeutic drug monitoring

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs.

01-08-2020

Head & neck

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update.

01-08-2020

International journal of epidemiology

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

01-08-2020

Breast (Edinburgh, Scotland)

The impact of menstruation persistence or recovery after chemotherapy on survival in young patients with hormone receptor negative breast cancer.

01-08-2020

Nature reviews. Immunology

Immune crosstalk in cancer progression and metastatic spread: a complex conversation.

01-08-2020

European journal of human genetics : EJHG

The uptake of predictive DNA testing in 40 families with a pathogenic BRCA1/BRCA2 variant. An evaluation of the proband-mediated procedure.

01-08-2020

Investigational new drugs

Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).

01-08-2020

Journal of medical genetics

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation.

01-08-2020

Nature genetics

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

01-08-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Feasibility of cone beam CT-guided library of plans strategy in pre-operative gastric cancer radiotherapy.

01-08-2020

Nucleosides, nucleotides & nucleic acids

Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase.

31-07-2020

BMC cancer

Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness.

31-07-2020

Cancers

The Perceived Impact of Length of the Diagnostic Pathway Is Associated with Health-Related Quality of Life of Sarcoma Survivors: Results from the Dutch Nationwide SURVSARC Study.

28-07-2020

Cancers

Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

27-07-2020

Breast cancer research : BCR

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.

25-07-2020

Cell reports

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

21-07-2020

Proceedings of the National Academy of Sciences of the United States of America

Stem cell lineage survival as a noisy competition for niche access.

21-07-2020

Trials

Internet-based cognitive rehabilitation for WORking Cancer survivors (i-WORC): study protocol of a randomized controlled trial.

20-07-2020

Molecular cell

RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.

16-07-2020

Insights into imaging

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice.

16-07-2020

Science translational medicine

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

15-07-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.

15-07-2020

The Journal of biological chemistry

Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).

10-07-2020

ACS infectious diseases

A Supramolecular Platform Technology for Bacterial Cell Surface Modification.

10-07-2020

Reversal of pre-existing NGFR-driven tumor and immune therapy resistance.

A DROP-IN beta probe for robot-assisted 68Ga-PSMA radioguided surgery: first ex vivo technology evaluation using prostate cancer specimens.

Applicator visualization using ultrashort echo time MRI for high-dose-rate endorectal brachytherapy.

Determination of the absolute bioavailability of oral imatinib using a stable isotopically labeled intravenous imatinib-d8 microdose.

Effects and moderators of coping skills training on symptoms of depression and anxiety in patients with cancer: Aggregate data and individual patient data meta-analyses.

Mass balance and metabolite profiling of 14C-guadecitabine in patients with advanced cancer.

No relation between docetaxel administration route and high-grade diarrhea incidence.

Adjuvant chemotherapy in small node-negative triple-negative breast cancer.

Radiogenomic Analysis of Breast Cancer by Linking MRI Phenotypes with Tumor Gene Expression.

First system for fully-automated multi-criterial treatment planning for a high-magnetic field MR-Linac applied to rectal cancer.

Updated efficacy results from the JAVELIN Renal 101 trial: first-line avelumab plus axitinib versus sunitinib in patients with advanced renal cell carcinoma.

Long-Term Effects of Radioiodine Treatment on Female Fertility in Survivors of Childhood Differentiated Thyroid Carcinoma.

Ascertainment of cancer in longitudinal research: The concordance between the Rotterdam Study and the Netherlands Cancer Registry.

Patterns and predictors of cancer-related fatigue in ovarian and endometrial cancers: 1-year longitudinal study.

Rationalizing the pathway to personalized neoadjuvant immunotherapy: the Lombard Street Approach.

Management of early melanoma recurrence despite adjuvant anti-PD-1 antibody therapy☆.

A semi-mechanistic model based on glutathione depletion to describe intra-individual reduction in busulfan clearance.

Towards a cancer mission in Horizon Europe: recommendations.

Tumor infiltrating lymphocytes (TIL) therapy in metastatic melanoma: boosting of neoantigen-specific T cell reactivity and long-term follow-up.

100 European core quality standards for cancer care and research centres.

Health-related quality of life and symptom burden of epithelioid hemangioendothelioma patients: a global patient-driven Facebook study in a very rare malignancy.

Distribution of Molecular Subtypes in Muscle-invasive Bladder Cancer Is Driven by Sex-specific Differences.

The DNA methylation landscape of advanced prostate cancer.

Selection of Patients for Organ Preservation After Chemoradiotherapy: MRI Identifies Poor Responders Who Can Go Straight to Surgery.

Cells of origin of lung cancers: lessons from mouse studies.

Phase I study of intermittent olaparib capsule or tablet dosing in combination with carboplatin and paclitaxel (part 2).

Evaluation of Extrapolation Methods to Predict Trough Concentrations to Guide Therapeutic Drug Monitoring of Oral Anticancer Drugs.

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update.

A Mendelian randomization analysis of circulating lipid traits and breast cancer risk.

The impact of menstruation persistence or recovery after chemotherapy on survival in young patients with hormone receptor negative breast cancer.

Immune crosstalk in cancer progression and metastatic spread: a complex conversation.

The uptake of predictive DNA testing in 40 families with a pathogenic BRCA1/BRCA2 variant. An evaluation of the proband-mediated procedure.

Phase I study of continuous olaparib capsule dosing in combination with carboplatin and/or paclitaxel (Part 1).

Variants of uncertain clinical significance in hereditary breast and ovarian cancer genes: best practices in functional analysis for clinical annotation.

Prostate cancer reactivates developmental epigenomic programs during metastatic progression.

Feasibility of cone beam CT-guided library of plans strategy in pre-operative gastric cancer radiotherapy.

Effect of dexamethasone on the antileukemic effect of cytarabine: role of deoxycytidine kinase.

Evaluating different adoption scenarios for TIL-therapy and the influence on its (early) cost-effectiveness.

The Perceived Impact of Length of the Diagnostic Pathway Is Associated with Health-Related Quality of Life of Sarcoma Survivors: Results from the Dutch Nationwide SURVSARC Study.

Age Does Matter in Adolescents and Young Adults versus Older Adults with Advanced Melanoma; A National Cohort Study Comparing Tumor Characteristics, Treatment Pattern, Toxicity and Response.

BRCAness digitalMLPA profiling predicts benefit of intensified platinum-based chemotherapy in triple-negative and luminal-type breast cancer.

Calorie Restriction Increases the Number of Competing Stem Cells and Decreases Mutation Retention in the Intestine.

Stem cell lineage survival as a noisy competition for niche access.

Internet-based cognitive rehabilitation for WORking Cancer survivors (i-WORC): study protocol of a randomized controlled trial.

RNA Pol II Length and Disorder Enable Cooperative Scaling of Transcriptional Bursting.

Follow-up after radiological intervention in oncology: ECIO-ESOI evidence and consensus-based recommendations for clinical practice.

Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance.

Bioanalytical method for the simultaneous quantification of irinotecan and its active metabolite SN-38 in mouse plasma and tissue homogenates using HPLC-fluorescence.

Cryo-electron microscopy structure and potential enzymatic function of human six-transmembrane epithelial antigen of the prostate 1 (STEAP1).

A Supramolecular Platform Technology for Bacterial Cell Surface Modification.

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A DROP-IN beta probe for robot-assisted ⁶⁸Ga-PSMA radioguided surgery: first ex vivo technology evaluation using prostate cancer specimens.

Mass balance and metabolite profiling of ¹⁴C-guadecitabine in patients with advanced cancer.

Management of early melanoma recurrence despite adjuvant anti-PD-1 antibody therapy^☆.