Publications

International journal of pharmaceutics

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice.

15-05-2020

Scientific reports

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

15-05-2020

Cancer research

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.

15-05-2020

PloS one

Early budget impact analysis on magnetic seed localization for non-palpable breast cancer surgery.

14-05-2020

Journal of medical Internet research

Web-Based Self-Management for Patients With Lymphoma: Assessment of the Reach of Intervention of a Randomized Controlled Trial.

14-05-2020

NPJ breast cancer

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

12-05-2020

NPJ breast cancer

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

12-05-2020

NPJ breast cancer

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

12-05-2020

Biosensors

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

11-05-2020

Pharmaceutical research

Phase I pharmacological study of continuous chronomodulated capecitabine treatment.

07-05-2020

Molecular cell

Life in the (Pluripotent) Fast Lane: Cdk1 Preserves the Epigenome to Maintain Pluripotency.

07-05-2020

Cancers

Surgery for Unresectable Stage IIIC and IV Melanoma in the Era of New Systemic Therapy.

07-05-2020

Molecular cell

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

07-05-2020

Journal of cancer research and therapeutics

Human papillomavirus-negative epithelial proliferations resembling condylomata acuminata in a patient receiving vemurafenib for Stage IV melanoma.

05-05-2020

Cell reports

Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine.

05-05-2020

European radiology

Value of combined multiparametric MRI and FDG-PET/CT to identify well-responding rectal cancer patients before the start of neoadjuvant chemoradiation.

01-05-2020

Journal of the National Cancer Institute

Trajectories of Cognitive Function Prior to Cancer Diagnosis: A Population-Based Study.

01-05-2020

European journal of cancer (Oxford, England : 1990)

Older versus younger adults with gastric cancer receiving perioperative treatment: Results from the CRITICS trial.

01-05-2020

Nature medicine

High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade.

01-05-2020

Annals of oncology : official journal of the European Society for Medical Oncology

Mise en place: toward neoadjuvant chemoimmunotherapy for early triple-negative breast cancer.

01-05-2020

Psycho-oncology

Unmet information needs of men with breast cancer and health professionals.

01-05-2020

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalytical assay for the new-generation ROS1/TRK/ALK inhibitor repotrectinib in mouse plasma and tissue homogenate using liquid chromatography-tandem mass spectrometry.

01-05-2020

CPT: pharmacometrics & systems pharmacology

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation.

01-05-2020

European journal of cancer (Oxford, England : 1990)

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure: real life data from a therapeutic drug monitoring programme.

01-05-2020

European radiology

Added value of MRI to endoscopic and endosonographic response assessment after neoadjuvant chemoradiotherapy in oesophageal cancer.

01-05-2020

Oncogene

Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

3D dosimetric verification of unity MR-linac treatments by portal dosimetry.

01-05-2020

The Lancet. Oncology

Outcome measures in multimodal rectal cancer trials.

01-05-2020

Clinical cancer research : an official journal of the American Association for Cancer Research

Association of Anti-TNF with Decreased Survival in Steroid Refractory Ipilimumab and Anti-PD1-Treated Patients in the Dutch Melanoma Treatment Registry.

01-05-2020

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.

01-05-2020

Magnetic resonance imaging

A workflow for automated segmentation of the liver surface, hepatic vasculature and biliary tree anatomy from multiphase MR images.

01-05-2020

Pigment cell & melanoma research

Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single-centre experience in patients with BRAF-mutated melanoma.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognosis of acute coronary syndromes after radiotherapy for breast cancer.

01-05-2020

Head & neck

Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.

01-05-2020

Journal of medical genetics

Three-step site-directed mutagenesis screen identifies pathogenic MLH1 variants associated with Lynch syndrome.

01-05-2020

Nature cancer

Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects.

01-05-2020

Cancer chemotherapy and pharmacology

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The use of real-world evidence to audit normal tissue complication probability models for acute esophageal toxicity in non-small cell lung cancer patients.

01-05-2020

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer.

01-05-2020

EJNMMI radiopharmacy and chemistry

Automated synthesis and quality control of [^99mTc]Tc-PSMA for radioguided surgery (in a [⁶⁸Ga]Ga-PSMA workflow).

01-05-2020

Endoscopy

Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Quantitative imaging for radiotherapy purposes.

01-05-2020

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The prognostic value of volumetric changes of the primary tumor measured on Cone Beam-CT during radiotherapy for concurrent chemoradiation in NSCLC patients.

01-05-2020

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Differences in Patient-Reported Outcomes That Are Most Frequently Detected in Randomized Controlled Trials in Patients With Solid Tumors: A Pooled Analysis of 229 Trials.

01-05-2020

Nature medicine

Caring for patients with cancer in the COVID-19 era.

01-05-2020

Cancer immunology research

Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells.

01-05-2020

Cancers

The Validity and Predictive Value of Blood-Based Biomarkers in Prediction of Response in the Treatment of Metastatic Non-Small Cell Lung Cancer: A Systematic Review.

30-04-2020

PloS one

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition.

29-04-2020

Oncotarget

Correction: Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

28-04-2020

Cellular and molecular gastroenterology and hepatology

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity.

25-04-2020

Brain accumulation of tivozanib is restricted by ABCB1 (P-glycoprotein) and ABCG2 (breast cancer resistance protein) in mice.

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

Endonuclease FEN1 Coregulates ERα Activity and Provides a Novel Drug Interface in Tamoxifen-Resistant Breast Cancer.

Early budget impact analysis on magnetic seed localization for non-palpable breast cancer surgery.

Web-Based Self-Management for Patients With Lymphoma: Assessment of the Reach of Intervention of a Randomized Controlled Trial.

Pitfalls in assessing stromal tumor infiltrating lymphocytes (sTILs) in breast cancer.

Application of a risk-management framework for integration of stromal tumor-infiltrating lymphocytes in clinical trials.

Report on computational assessment of Tumor Infiltrating Lymphocytes from the International Immuno-Oncology Biomarker Working Group.

Fecal Volatile Organic Compound Profiles are Not Influenced by Gestational Age and Mode of Delivery: A Longitudinal Multicenter Cohort Study.

Phase I pharmacological study of continuous chronomodulated capecitabine treatment.

Life in the (Pluripotent) Fast Lane: Cdk1 Preserves the Epigenome to Maintain Pluripotency.

Surgery for Unresectable Stage IIIC and IV Melanoma in the Era of New Systemic Therapy.

Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels.

Human papillomavirus-negative epithelial proliferations resembling condylomata acuminata in a patient receiving vemurafenib for Stage IV melanoma.

Challenges in Establishing Pure Lung Cancer Organoids Limit Their Utility for Personalized Medicine.

Value of combined multiparametric MRI and FDG-PET/CT to identify well-responding rectal cancer patients before the start of neoadjuvant chemoradiation.

Trajectories of Cognitive Function Prior to Cancer Diagnosis: A Population-Based Study.

Older versus younger adults with gastric cancer receiving perioperative treatment: Results from the CRITICS trial.

High systemic and tumor-associated IL-8 correlates with reduced clinical benefit of PD-L1 blockade.

Mise en place: toward neoadjuvant chemoimmunotherapy for early triple-negative breast cancer.

Unmet information needs of men with breast cancer and health professionals.

Bioanalytical assay for the new-generation ROS1/TRK/ALK inhibitor repotrectinib in mouse plasma and tissue homogenate using liquid chromatography-tandem mass spectrometry.

Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation.

Concomitant intake of abiraterone acetate and food to increase pharmacokinetic exposure: real life data from a therapeutic drug monitoring programme.

Added value of MRI to endoscopic and endosonographic response assessment after neoadjuvant chemoradiotherapy in oesophageal cancer.

Integrative analysis of genomic amplification-dependent expression and loss-of-function screen identifies ASAP1 as a driver gene in triple-negative breast cancer progression.

3D dosimetric verification of unity MR-linac treatments by portal dosimetry.

Outcome measures in multimodal rectal cancer trials.

Association of Anti-TNF with Decreased Survival in Steroid Refractory Ipilimumab and Anti-PD1-Treated Patients in the Dutch Melanoma Treatment Registry.

International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.

A workflow for automated segmentation of the liver surface, hepatic vasculature and biliary tree anatomy from multiphase MR images.

Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single-centre experience in patients with BRAF-mutated melanoma.

Prognosis of acute coronary syndromes after radiotherapy for breast cancer.

Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.

Three-step site-directed mutagenesis screen identifies pathogenic MLH1 variants associated with Lynch syndrome.

Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects.

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

The use of real-world evidence to audit normal tissue complication probability models for acute esophageal toxicity in non-small cell lung cancer patients.

Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer.

Automated synthesis and quality control of [99mTc]Tc-PSMA for radioguided surgery (in a [68Ga]Ga-PSMA workflow).

Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020.

Quantitative imaging for radiotherapy purposes.

The prognostic value of volumetric changes of the primary tumor measured on Cone Beam-CT during radiotherapy for concurrent chemoradiation in NSCLC patients.

Differences in Patient-Reported Outcomes That Are Most Frequently Detected in Randomized Controlled Trials in Patients With Solid Tumors: A Pooled Analysis of 229 Trials.

Caring for patients with cancer in the COVID-19 era.

Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells.

The Validity and Predictive Value of Blood-Based Biomarkers in Prediction of Response in the Treatment of Metastatic Non-Small Cell Lung Cancer: A Systematic Review.

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition.

Correction: Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity.

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Automated synthesis and quality control of [^99mTc]Tc-PSMA for radioguided surgery (in a [⁶⁸Ga]Ga-PSMA workflow).