Publications

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

International validation of the EORTC CAT Core: a new adaptive instrument for measuring core quality of life domains in cancer.

Magnetic resonance imaging

A workflow for automated segmentation of the liver surface, hepatic vasculature and biliary tree anatomy from multiphase MR images.

Pigment cell & melanoma research

Switch to checkpoint inhibition after targeted therapy at time of progression or during ongoing response: A retrospective single-centre experience in patients with BRAF-mutated melanoma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prognosis of acute coronary syndromes after radiotherapy for breast cancer.

Head & neck

Methotrexate plus or minus cetuximab as first-line treatment in a recurrent or metastatic (R/M) squamous cell carcinoma population of the head and neck (SCCHN), unfit for cisplatin combination treatment, a phase Ib-randomized phase II study Commence.

Journal of medical genetics

Three-step site-directed mutagenesis screen identifies pathogenic MLH1 variants associated with Lynch syndrome.

Nature cancer

Age-correlated protein and transcript expression in breast cancer and normal breast tissues is dominated by host endocrine effects.

Cancer chemotherapy and pharmacology

Phase I study of lapatinib plus trametinib in patients with KRAS-mutant colorectal, non-small cell lung, and pancreatic cancer.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The use of real-world evidence to audit normal tissue complication probability models for acute esophageal toxicity in non-small cell lung cancer patients.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Adherence to and satisfaction with low-intensity physical activity and supervised moderate-high intensity exercise during chemotherapy for breast cancer.

EJNMMI radiopharmacy and chemistry

Automated synthesis and quality control of [^99mTc]Tc-PSMA for radioguided surgery (in a [⁶⁸Ga]Ga-PSMA workflow).

Endoscopy

Self-expandable metal stents for obstructing colonic and extracolonic cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline - Update 2020.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Quantitative imaging for radiotherapy purposes.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The prognostic value of volumetric changes of the primary tumor measured on Cone Beam-CT during radiotherapy for concurrent chemoradiation in NSCLC patients.

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Differences in Patient-Reported Outcomes That Are Most Frequently Detected in Randomized Controlled Trials in Patients With Solid Tumors: A Pooled Analysis of 229 Trials.

Nature medicine

Caring for patients with cancer in the COVID-19 era.

Cancer immunology research

Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells.

Cancers

The Validity and Predictive Value of Blood-Based Biomarkers in Prediction of Response in the Treatment of Metastatic Non-Small Cell Lung Cancer: A Systematic Review.

30-04-2020

PloS one

A genome-wide enrichment screen identifies NUMA1-loss as a resistance mechanism against mitotic cell-death induced by BMI1 inhibition.

29-04-2020

Oncotarget

Correction: Neoadjuvant olaparib targets hypoxia to improve radioresponse in a homologous recombination-proficient breast cancer model.

28-04-2020

Cellular and molecular gastroenterology and hepatology

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity.

25-04-2020

Cancers

Healthcare Costs of Metastatic Cutaneous Melanoma in the Era of Immunotherapeutic and Targeted Drugs.

18-04-2020

Clinical and experimental rheumatology

Acrocyanosis after neoadjuvant ipilimumab plus nivolumab: a case report.

18-04-2020

Journal of immunology (Baltimore, Md. : 1950)

IFN-Stimulated Gene 15 Is an Alarmin that Boosts the CTL Response via an Innate, NK Cell-Dependent Route.

International journal of cancer

IGF-1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER-positive breast cancer.

NPJ precision oncology

Accurate surgical navigation with real-time tumor tracking in cancer surgery.

International journal of cancer

The prognostic value of the tumor-stroma ratio is most discriminative in patients with grade III or triple-negative breast cancer.

NPJ precision oncology

Accurate surgical navigation with real-time tumor tracking in cancer surgery.

08-04-2020

Nature communications

Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions.

08-04-2020

Proceedings of the National Academy of Sciences of the United States of America

Targeting the cyclin-dependent kinase 5 in metastatic melanoma.

07-04-2020

Die Pharmazie

Development and validation of an LC-MS/MS method for the quantification of imatinib and imatinib-d8 in human plasma for the support of an absolute bioavailability microdose trial.

06-04-2020

Cell stem cell

Plasticity of Lgr5-Negative Cancer Cells Drives Metastasis in Colorectal Cancer.

02-04-2020

Key Publication

JAMA oncology

Association Between Immune-Related Adverse Events and Recurrence-Free Survival Among Patients With Stage III Melanoma Randomized to Receive Pembrolizumab or Placebo: A Secondary Analysis of a Randomized Clinical Trial.

World journal of urology

Best practices in near-infrared fluorescence imaging with indocyanine green (NIRF/ICG)-guided robotic urologic surgery: a systematic review-based expert consensus.

International journal of cancer

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica

Hierarchical clustering of PI3K and MAPK pathway proteins in breast cancer intrinsic subtypes.

Journal of cancer survivorship : research and practice

Type of cancer treatment and cognitive symptoms in working cancer survivors: an 18-month follow-up study.

British journal of cancer

Phase 1 study of the pan-HER inhibitor dacomitinib plus the MEK1/2 inhibitor PD-0325901 in patients with KRAS-mutation-positive colorectal, non-small-cell lung and pancreatic cancer.

Nature medicine

Neoadjuvant immunotherapy leads to pathological responses in MMR-proficient and MMR-deficient early-stage colon cancers.

International journal of radiation oncology, biology, physics

Five-Year Results of the Preoperative Accelerated Partial Breast Irradiation (PAPBI) Trial.

European urology oncology

Deferred Cytoreductive Nephrectomy Following Presurgical Vascular Endothelial Growth Factor Receptor-targeted Therapy in Patients with Primary Metastatic Clear Cell Renal Cell Carcinoma: A Pooled Analysis of Prospective Trial Data.

Journal of adolescent and young adult oncology

Exploring Communication About Intimacy and Sexuality: What Are the Preferences of Adolescents and Young Adults with Cancer and Their Health Care Professionals?

Molecular cancer research : MCR

Diverse BRAF Gene Fusions Confer Resistance to EGFR-Targeted Therapy via Differential Modulation of BRAF Activity.

Breast cancer research and treatment

Breast cancer outcome in relation to bone mineral density and bisphosphonate use: a sub-study of the DATA trial.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiotherapy after primary CHEMotherapy (RAPCHEM): Practice variation in a Dutch registration study (BOOG 2010-03).

Genome research

Inhibition of transcription leads to rewiring of locus-specific chromatin proteomes.

Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

New Approaches to SCLC Therapy: From the Laboratory to the Clinic.

Future oncology (London, England)

Vorinostat in patients with resistant BRAF^V600E mutated advanced melanoma: a proof of concept study.

Cancer discovery

Characteristics and Outcome of AKT1^E17K-Mutant Breast Cancer Defined through AACR Project GENIE, a Clinicogenomic Registry.