Publications

Trends in cancer

Tissue architecture in tumor initiation and progression.

01-06-2022

European urology

Reply to Kamal Kant Sahu's Letter to the Editor re: Veerle H. Groen, Karin Haustermans, Floris J. Pos, et al. Patterns of Failure Following External Beam Radiotherapy With or Without an Additional Focal Boost in the Randomized Controlled FLAME Trial for Localized Prostate Cancer. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2021.12.012.

01-06-2022

Cancer chemotherapy and pharmacology

Comparison of docetaxel pharmacokinetics between castration-resistant and hormone-sensitive metastatic prostate cancer patients.

01-06-2022

Journal of cancer survivorship : research and practice

Evaluation of two strategies to implement physical cancer rehabilitation guidelines for survivors of abdominopelvic cavity tumors: a controlled before-and-after study.

01-06-2022

Gynecologic oncology

Clinical implementation of routine diagnostic laparoscopy to guide initial treatment in patients with advanced-stage epithelial ovarian cancer in Dutch clinical practice: Evaluation of support and a budget impact analysis.

01-06-2022

Nature reviews. Cancer

Exploiting senescence for the treatment of cancer.

01-06-2022

Clinical and translational gastroenterology

Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

01-06-2022

Preventive medicine

Towards implementation of comprehensive breast cancer risk prediction tools in health care for personalised prevention.

01-06-2022

Patient education and counseling

Patient involvement in clinical pathway development, implementation and evaluation - A scoping review of international literature.

01-06-2022

Nature medicine

Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial.

01-06-2022

British journal of cancer

Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients.

01-06-2022

British journal of cancer

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity.

01-06-2022

Journal of cell science

Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.

01-06-2022

Annals of surgical oncology

Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

01-06-2022

Nature structural & molecular biology

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.

01-06-2022

Urologic oncology

Minimally invasive evaluation of the clinically negative inguinal node in penile cancer: Dynamic sentinel node biopsy.

01-06-2022

European urology oncology

Surgical Safety of Deferred Cytoreductive Nephrectomy Following Pretreatment with Immune Checkpoint Inhibitor-based Dual Combination Therapy.

01-06-2022

Drugs - real world outcomes

Being Transparent About Brilliant Failures: An Attempt to Use Real-World Data in a Disease Model for Patients with Castration-Resistant Prostate Cancer.

01-06-2022

ESMO open

Systemic treatment of advanced clear cell sarcoma: results from a retrospective international series from the World Sarcoma Network.

01-06-2022

Nature reviews. Clinical oncology

COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety.

01-06-2022

The Journal of pathology

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

01-06-2022

ESMO open

Setting the international research agenda for sarcoma together with patients and carers: first results of the Sarcoma Patient EuroNet (SPAEN) priority setting partnership.

01-06-2022

JACC. CardioOncology

Physical Activity and Cardiac Function in Long-Term Breast Cancer Survivors: A Cross-Sectional Study.

01-06-2022

Annals of surgical oncology

Real-Time Wireless Tumor Tracking in Navigated Liver Resections: An Ex Vivo Feasibility Study.

01-06-2022

Journal of cachexia, sarcopenia and muscle

The association between skeletal muscle measures and chemotherapy-induced toxicity in non-small cell lung cancer patients.

01-06-2022

Nature genetics

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.

01-06-2022

Scientific reports

Deep learning body-composition analysis of clinically acquired CT-scans estimates creatinine excretion with high accuracy in patients and healthy individuals.

30-05-2022

Breast cancer research : BCR

Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer: a randomized controlled trial (PAM study).

26-05-2022

Science (New York, N.Y.)

Posttranslational modification of microtubules by the MATCAP detyrosinase.

20-05-2022

Cancers

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells.

19-05-2022

Genome medicine

Breast cancer risks associated with missense variants in breast cancer susceptibility genes.

18-05-2022

Frontiers in immunology

In Silico Analysis Predicts a Limited Impact of SARS-CoV-2 Variants on CD8 T Cell Recognition.

17-05-2022

Cancer research

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.

16-05-2022

Cancer

Switching the scope from "how to identify cancer survivors" to "who is participating in cancer survivorship research": A proposal for a new focus.

15-05-2022

Frontiers in pharmacology

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.

14-05-2022

American journal of nuclear medicine and molecular imaging

Precision surgery: the role of intra-operative real-time image guidance - outcomes from a multidisciplinary European consensus conference.

11-05-2022

Journal of translational medicine

The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

10-05-2022

Cancers

External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort.

10-05-2022

Scientific reports

Cost-utility analysis on robot-assisted and laparoscopic prostatectomy based on long-term functional outcomes.

10-05-2022

BMC cancer

Image-guided navigation for locally advanced primary and locally recurrent rectal cancer: evaluation of its early cost-effectiveness.

06-05-2022

NPJ breast cancer

Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance.

06-05-2022

Molecular cell

A walk through the SMC cycle: From catching DNAs to shaping the genome.

05-05-2022

Clinical epigenetics

Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer.

04-05-2022

Biophysical journal

Following the tracks: How transcription factor binding dynamics control transcription.

03-05-2022

Cancer investigation

Late Mortality in Childhood Cancer Survivors according to Pediatric Cancer Diagnosis and Treatment Era in the Dutch LATER Cohort.

01-05-2022

Nature cancer

Author Correction: The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

01-05-2022

Nature reviews. Immunology

The precursors of CD8⁺ tissue resident memory T cells: from lymphoid organs to infected tissues.

01-05-2022

European journal of nuclear medicine and molecular imaging

[¹⁸F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma.

01-05-2022

Cancer chemotherapy and pharmacology

Is age just a number? A population pharmacokinetic study of gemcitabine.

01-05-2022

Biomedical optics express

Discriminating healthy from tumor tissue in breast lumpectomy specimens using deep learning-based hyperspectral imaging.

01-05-2022

Tissue architecture in tumor initiation and progression.

Comparison of docetaxel pharmacokinetics between castration-resistant and hormone-sensitive metastatic prostate cancer patients.

Evaluation of two strategies to implement physical cancer rehabilitation guidelines for survivors of abdominopelvic cavity tumors: a controlled before-and-after study.

Clinical implementation of routine diagnostic laparoscopy to guide initial treatment in patients with advanced-stage epithelial ovarian cancer in Dutch clinical practice: Evaluation of support and a budget impact analysis.

Exploiting senescence for the treatment of cancer.

Lessons From a Systematic Literature Search on Diagnostic DNA Methylation Biomarkers for Colorectal Cancer: How to Increase Research Value and Decrease Research Waste?

Towards implementation of comprehensive breast cancer risk prediction tools in health care for personalised prevention.

Patient involvement in clinical pathway development, implementation and evaluation - A scoping review of international literature.

Personalized response-directed surgery and adjuvant therapy after neoadjuvant ipilimumab and nivolumab in high-risk stage III melanoma: the PRADO trial.

Adjuvant capecitabine-containing chemotherapy benefit and homologous recombination deficiency in early-stage triple-negative breast cancer patients.

Peritoneal metastases from colorectal cancer belong to Consensus Molecular Subtype 4 and are sensitised to oxaliplatin by inhibiting reducing capacity.

Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.

Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.

Minimally invasive evaluation of the clinically negative inguinal node in penile cancer: Dynamic sentinel node biopsy.

Surgical Safety of Deferred Cytoreductive Nephrectomy Following Pretreatment with Immune Checkpoint Inhibitor-based Dual Combination Therapy.

Being Transparent About Brilliant Failures: An Attempt to Use Real-World Data in a Disease Model for Patients with Castration-Resistant Prostate Cancer.

Systemic treatment of advanced clear cell sarcoma: results from a retrospective international series from the World Sarcoma Network.

COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety.

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

Setting the international research agenda for sarcoma together with patients and carers: first results of the Sarcoma Patient EuroNet (SPAEN) priority setting partnership.

Physical Activity and Cardiac Function in Long-Term Breast Cancer Survivors: A Cross-Sectional Study.

Real-Time Wireless Tumor Tracking in Navigated Liver Resections: An Ex Vivo Feasibility Study.

The association between skeletal muscle measures and chemotherapy-induced toxicity in non-small cell lung cancer patients.

Genomic analysis defines clonal relationships of ductal carcinoma in situ and recurrent invasive breast cancer.

Deep learning body-composition analysis of clinically acquired CT-scans estimates creatinine excretion with high accuracy in patients and healthy individuals.

Effect of physical exercise on cognitive function after chemotherapy in patients with breast cancer: a randomized controlled trial (PAM study).

Posttranslational modification of microtubules by the MATCAP detyrosinase.

Dynamic Visualization of TGF-β/SMAD3 Transcriptional Responses in Single Living Cells.

Breast cancer risks associated with missense variants in breast cancer susceptibility genes.

In Silico Analysis Predicts a Limited Impact of SARS-CoV-2 Variants on CD8 T Cell Recognition.

Liver Colonization by Colorectal Cancer Metastases Requires YAP-Controlled Plasticity at the Micrometastatic Stage.

Switching the scope from "how to identify cancer survivors" to "who is participating in cancer survivorship research": A proposal for a new focus.

Small Molecule Inhibitor Targeting CDT1/Geminin Protein Complex Promotes DNA Damage and Cell Death in Cancer Cells.

Precision surgery: the role of intra-operative real-time image guidance - outcomes from a multidisciplinary European consensus conference.

The "Great Debate" at Melanoma Bridge 2021, December 2nd-4th, 2021.

External Validation of Two Established Clinical Risk Scores Predicting Outcome after Local Treatment of Colorectal Liver Metastases in a Nationwide Cohort.

Cost-utility analysis on robot-assisted and laparoscopic prostatectomy based on long-term functional outcomes.

Image-guided navigation for locally advanced primary and locally recurrent rectal cancer: evaluation of its early cost-effectiveness.

Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance.

A walk through the SMC cycle: From catching DNAs to shaping the genome.

Androgen receptor reprogramming demarcates prognostic, context-dependent gene sets in primary and metastatic prostate cancer.

Following the tracks: How transcription factor binding dynamics control transcription.

Late Mortality in Childhood Cancer Survivors according to Pediatric Cancer Diagnosis and Treatment Era in the Dutch LATER Cohort.

Author Correction: The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

The precursors of CD8+ tissue resident memory T cells: from lymphoid organs to infected tissues.

[18F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma.

Is age just a number? A population pharmacokinetic study of gemcitabine.

Discriminating healthy from tumor tissue in breast lumpectomy specimens using deep learning-based hyperspectral imaging.

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The precursors of CD8⁺ tissue resident memory T cells: from lymphoid organs to infected tissues.

[¹⁸F]FDG-PET accurately identifies pathological response early upon neoadjuvant immune checkpoint blockade in head and neck squamous cell carcinoma.