Publications

Nature communications

An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer.

07-11-2024

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Local control and toxicity after stereotactic radiotherapy in brain metastases patients and the impact of novel systemic treatments.

01-11-2024

Nature genetics

Base editing screens define the genetic landscape of cancer drug resistance mechanisms.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Seven-year analysis of adjuvant pembrolizumab versus placebo in stage III melanoma in the EORTC1325 / KEYNOTE-054 trial.

01-11-2024

Health policy and technology

Perspectives on access to imaging digital health records in oncology: A mixed methods systematic review.

01-11-2024

Trends in biochemical sciences

The quest to identify ADP-ribosylation readers: methodological advances.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry.

01-11-2024

Nature medicine

Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial.

01-11-2024

Thyroid : official journal of the American Thyroid Association

The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Improving completion rates of patient-reported outcome measures in cancer clinical trials: Scoping review investigating the implications for trial designs.

01-11-2024

Nature medicine

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

01-11-2024

Nature reviews. Cancer

Macrophages and T cells in metabolic disorder-associated cancers.

01-11-2024

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Freehand SPECT Combined with 3-Dimensional Light Detection and Ranging as Alternative Means of Specimen Scanning During Prostate Cancer Surgery.

01-11-2024

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients.

01-11-2024

Clinical lung cancer

Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial.

01-11-2024

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Quality of life and functional outcome of rectal cancer patients: A prospective cohort study.

01-11-2024

Molecular oncology

A scenario-drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology.

01-11-2024

Clinical and translational radiation oncology

Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708).

01-11-2024

EMBO reports

Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Nature and management of melanoma recurrences following adjuvant anti-PD-1 based therapy.

01-11-2024

The EMBO journal

Chromatin protein complexes involved in gene repression in lamina-associated domains.

01-11-2024

European journal of cancer (Oxford, England : 1990)

Instrumental activities of daily living in neuro-oncology: International validation of the EORTC IADL-BN32 questionnaire.

01-11-2024

eLife

Large-scale analysis of the integration of enhancer-enhancer signals by promoters.

28-10-2024

bioRxiv : the preprint server for biology

An integrated view of the structure and function of the human 4D nucleome.

27-10-2024

BJC reports

Long-term survival following anti-PD-(L)1 monotherapy in advanced urothelial cancer and an assessment of potential prognostic clinical factors: a multicentre observational study.

23-10-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Evaluating a digital tool for supporting people affected by breast cancer: a prospective randomized controlled trial-the ADAPT study.

21-10-2024

Nature communications

Cancer treatment monitoring using cell-free DNA fragmentomes.

21-10-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Academic Uphill Battle to Personalize Treatment for Patients With Stage II/III Triple-Negative Breast Cancer.

20-10-2024

Nature communications

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.

17-10-2024

Digestive diseases (Basel, Switzerland)

Treatment of Colorectal Lung Metastases: Two Centers Retrospective Study.

16-10-2024

BMJ open

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC).

16-10-2024

Drug metabolism and disposition: the biological fate of chemicals

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

16-10-2024

International journal of cancer

Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study.

15-10-2024

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

15-10-2024

Journal of immunology (Baltimore, Md. : 1950)

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo.

15-10-2024

Cancer cell

Architecture sets the path: Breast cancer subtypes differently shape the early brain metastatic niche.

14-10-2024

BMJ open

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.

09-10-2024

American journal of epidemiology

Regression calibration of self-reported mobile phone use to optimize quantitative risk estimation in the COSMOS study.

07-10-2024

Molecular pharmaceutics

Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.

07-10-2024

Communications biology

Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.

04-10-2024

Structure (London, England : 1993)

The future of integrated structural biology.

03-10-2024

Breast (Edinburgh, Scotland)

DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS.

01-10-2024

Medical image analysis

Improving lesion volume measurements on digital mammograms.

01-10-2024

Journal of genetic counseling

Psychosocial issues of individuals undergoing surveillance for increased risk of melanoma and pancreatic cancer due to a germline CDKN2A variant: A focus group study.

01-10-2024

Physics and imaging in radiation oncology

Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer.

01-10-2024

Dysphagia

Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

01-10-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Quality of life issues in patients with ductal carcinoma in situ: a systematic review.

01-10-2024

Plastic and reconstructive surgery

Efficacy of a Decision Aid in Breast Cancer Patients Considering Immediate Reconstruction: Results of a Randomized Controlled Trial.

01-10-2024

ESMO open

ESMO Resilience Task Force recommendations to manage psychosocial risks, optimise well-being, and reduce burnout in oncology.

01-10-2024

European journal of oncology nursing : the official journal of European Oncology Nursing Society

Self-perceived cognitive impairment in the first year after breast cancer and the identification of at-risk patients.

01-10-2024

An explainable longitudinal multi-modal fusion model for predicting neoadjuvant therapy response in women with breast cancer.

Local control and toxicity after stereotactic radiotherapy in brain metastases patients and the impact of novel systemic treatments.

Base editing screens define the genetic landscape of cancer drug resistance mechanisms.

Seven-year analysis of adjuvant pembrolizumab versus placebo in stage III melanoma in the EORTC1325 / KEYNOTE-054 trial.

Perspectives on access to imaging digital health records in oncology: A mixed methods systematic review.

The quest to identify ADP-ribosylation readers: methodological advances.

Adjuvant immunotherapy in older patients with stage III and resected stage IV melanoma: Toxicity and recurrence-free survival outcomes from the Dutch melanoma treatment registry.

Neoadjuvant nivolumab and relatlimab in locally advanced MMR-deficient colon cancer: a phase 2 trial.

The Cancer-Specific Health Economic Measure QLU-C10D is Valid and Responsive for Assessing Health Utility in Patients with Thyroid Cancer.

Improving completion rates of patient-reported outcome measures in cancer clinical trials: Scoping review investigating the implications for trial designs.

Neoadjuvant nivolumab or nivolumab plus ipilimumab in early-stage triple-negative breast cancer: a phase 2 adaptive trial.

Macrophages and T cells in metabolic disorder-associated cancers.

Freehand SPECT Combined with 3-Dimensional Light Detection and Ranging as Alternative Means of Specimen Scanning During Prostate Cancer Surgery.

Using a modified Delphi procedure to select a PRO-CTCAE-based subset for patient-reported symptomatic toxicity monitoring in rectal cancer patients.

Association of Serum Biomarkers With Neurocognitive Decline After PCI in Small Cell Lung Cancer: An Exploratory Study of the Phase III NCT01780675 Trial.

Quality of life and functional outcome of rectal cancer patients: A prospective cohort study.

A scenario-drafting study to explore potential future implementation pathways of circulating tumor DNA testing in oncology.

Feasibility and safety of single-fraction sub-ablative radiotherapy with systemic therapy in colorectal cancer patients with ≤ 10 metastases: A multicenter pilot study (NCT05375708).

Reduction of chromosomal instability and inflammation is a common aspect of adaptation to aneuploidy.

Nature and management of melanoma recurrences following adjuvant anti-PD-1 based therapy.

Chromatin protein complexes involved in gene repression in lamina-associated domains.

Instrumental activities of daily living in neuro-oncology: International validation of the EORTC IADL-BN32 questionnaire.

Large-scale analysis of the integration of enhancer-enhancer signals by promoters.

An integrated view of the structure and function of the human 4D nucleome.

Long-term survival following anti-PD-(L)1 monotherapy in advanced urothelial cancer and an assessment of potential prognostic clinical factors: a multicentre observational study.

Evaluating a digital tool for supporting people affected by breast cancer: a prospective randomized controlled trial-the ADAPT study.

Cancer treatment monitoring using cell-free DNA fragmentomes.

Academic Uphill Battle to Personalize Treatment for Patients With Stage II/III Triple-Negative Breast Cancer.

OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1S824.

Treatment of Colorectal Lung Metastases: Two Centers Retrospective Study.

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC).

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study.

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo.

Architecture sets the path: Breast cancer subtypes differently shape the early brain metastatic niche.

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.

Regression calibration of self-reported mobile phone use to optimize quantitative risk estimation in the COSMOS study.

Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.

Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.

The future of integrated structural biology.

DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS.

Improving lesion volume measurements on digital mammograms.

Psychosocial issues of individuals undergoing surveillance for increased risk of melanoma and pancreatic cancer due to a germline CDKN2A variant: A focus group study.

Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer.

Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

Quality of life issues in patients with ductal carcinoma in situ: a systematic review.

Efficacy of a Decision Aid in Breast Cancer Patients Considering Immediate Reconstruction: Results of a Randomized Controlled Trial.

ESMO Resilience Task Force recommendations to manage psychosocial risks, optimise well-being, and reduce burnout in oncology.

Self-perceived cognitive impairment in the first year after breast cancer and the identification of at-risk patients.

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OTUD5 promotes end-joining of deprotected telomeres by promoting ATM-dependent phosphorylation of KAP1^S824.