Publications

BMJ open

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC).

16-10-2024

Drug metabolism and disposition: the biological fate of chemicals

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

16-10-2024

International journal of cancer

Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study.

15-10-2024

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

15-10-2024

Journal of immunology (Baltimore, Md. : 1950)

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo.

15-10-2024

Cancer cell

Architecture sets the path: Breast cancer subtypes differently shape the early brain metastatic niche.

14-10-2024

BMJ open

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.

09-10-2024

American journal of epidemiology

Regression calibration of self-reported mobile phone use to optimize quantitative risk estimation in the COSMOS study.

07-10-2024

Molecular pharmaceutics

Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.

07-10-2024

Communications biology

Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.

04-10-2024

Structure (London, England : 1993)

The future of integrated structural biology.

03-10-2024

Breast (Edinburgh, Scotland)

DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS.

01-10-2024

Medical image analysis

Improving lesion volume measurements on digital mammograms.

01-10-2024

Journal of genetic counseling

Psychosocial issues of individuals undergoing surveillance for increased risk of melanoma and pancreatic cancer due to a germline CDKN2A variant: A focus group study.

01-10-2024

Physics and imaging in radiation oncology

Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer.

01-10-2024

Dysphagia

Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

01-10-2024

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Quality of life issues in patients with ductal carcinoma in situ: a systematic review.

01-10-2024

Plastic and reconstructive surgery

Efficacy of a Decision Aid in Breast Cancer Patients Considering Immediate Reconstruction: Results of a Randomized Controlled Trial.

01-10-2024

ESMO open

ESMO Resilience Task Force recommendations to manage psychosocial risks, optimise well-being, and reduce burnout in oncology.

01-10-2024

European journal of oncology nursing : the official journal of European Oncology Nursing Society

Self-perceived cognitive impairment in the first year after breast cancer and the identification of at-risk patients.

01-10-2024

Journal of cancer survivorship : research and practice

Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.

01-10-2024

Nature medicine

Supervised, structured and individualized exercise in metastatic breast cancer: a randomized controlled trial.

01-10-2024

Key Publication

Seminars in radiation oncology

Future of Multidisciplinary Team in the Context of Adaptive Therapy.

01-10-2024

Physics and imaging in radiation oncology

Evaluating the effect of higher Monte Carlo statistical uncertainties on accumulated doses after daily adaptive fractionated radiotherapy in prostate cancer.

01-10-2024

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy of TIL therapy in advanced cutaneous melanoma in the current immuno-oncology era: updated systematic review and meta-analysis.

01-10-2024

European urology oncology

Activity of Lutetium-177 Prostate-specific Membrane Antigen and Determinants of Outcomes in Patients with Metastatic Castration-resistant Prostate Cancer Previously Treated with Cabazitaxel: The PACAP Study.

01-10-2024

Nature reviews. Cancer

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.

01-10-2024

Molecular oncology

A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm.

01-10-2024

Critical reviews in oncology/hematology

Factors for a broad technology assessment of comprehensive genomic profiling in advanced cancer, a systematic review.

01-10-2024

Dysphagia

Correction to: Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

01-10-2024

Scandinavian journal of work, environment & health

Associations of night shift work with weight gain among female nurses in The Netherlands: results of a prospective cohort study.

01-10-2024

Physics and imaging in radiation oncology

Incorporating patient-specific information for the development of rectal tumor auto-segmentation models for online adaptive magnetic resonance Image-guided radiotherapy.

01-10-2024

ESMO open

Characteristics and clinical outcomes of breast cancer in young BRCA carriers according to tumor histology.

01-10-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment: Results from the Drug Rediscovery Protocol.

01-10-2024

International journal of surgery (London, England)

Recurrence of breast cancer after reconstruction with macro-textured silicone breast implants: a retrospective cohort study.

01-10-2024

Nucleic acids research

ADARp150 counteracts whole genome duplication.

23-09-2024

Cell

Macrophage-mediated myelin recycling fuels brain cancer malignancy.

19-09-2024

CVIR endovascular

Correction: Interventional solutions for post‑surgical problems: a lymphatic leaks review.

17-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.

13-09-2024

Communications biology

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.

13-09-2024

Frontiers in immunology

mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy.

11-09-2024

Nature communications

Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.

11-09-2024

Acta oncologica (Stockholm, Sweden)

High-dose chemotherapy for patients with stage III breast cancer with homologous recombination deficiency: a discrete choice experiment among healthcare providers.

10-09-2024

Cancer cell

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8⁺ T cells.

09-09-2024

The oncologist

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

06-09-2024

American journal of human genetics

Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.

05-09-2024

medRxiv : the preprint server for health sciences

Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.

04-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Efficacy of Pembrolizumab and Biomarker Analysis in Patients with WGS-Based Intermediate to High Tumor Mutational Load: Results from the Drug Rediscovery Protocol.

03-09-2024

Clinical cancer research : an official journal of the American Association for Cancer Research

Maximizing Treatment Opportunities: Assessing Protocol Waivers' Impact on Safety and Outcome in the Drug Rediscovery Protocol.

03-09-2024

Toxicology and applied pharmacology

The role of drug efflux and uptake transporters in the plasma pharmacokinetics and tissue disposition of morphine and its main metabolites.

01-09-2024

Optimised treatment of patients with enlarged lateral lymph nodes in rectal cancer: protocol of an international, multicentre, prospective registration study after extensive multidisciplinary training (LaNoReC).

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

Adjuvant treatment with anti-PD-1 in acral melanoma: A nationwide study.

Development and validation of an LC-MS/MS method for simultaneous quantification of eight drugs in plasma and brain: Application in a pharmacokinetic study in mice.

ITPK1 Sensitizes Tumor Cells to IgA-dependent Neutrophil Killing In Vivo.

Architecture sets the path: Breast cancer subtypes differently shape the early brain metastatic niche.

Cohort profile: a nationwide study in Dutch CHEK2 c.1100delC families using the infrastructure of the HEreditary Breast and Ovarian cancer study Netherlands - Hebon-CHEK2.

Regression calibration of self-reported mobile phone use to optimize quantitative risk estimation in the COSMOS study.

Brain Exposure to the Macrocyclic ALK Inhibitor Zotizalkib is Restricted by ABCB1, and Its Plasma Disposition is Affected by Mouse Carboxylesterase 1c.

Selective inhibition of HDAC class IIA as therapeutic intervention for KMT2A-rearranged acute lymphoblastic leukemia.

The future of integrated structural biology.

DCIS knowledge of women choosing between active surveillance and surgery for low-risk DCIS.

Improving lesion volume measurements on digital mammograms.

Psychosocial issues of individuals undergoing surveillance for increased risk of melanoma and pancreatic cancer due to a germline CDKN2A variant: A focus group study.

Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer.

Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

Quality of life issues in patients with ductal carcinoma in situ: a systematic review.

Efficacy of a Decision Aid in Breast Cancer Patients Considering Immediate Reconstruction: Results of a Randomized Controlled Trial.

ESMO Resilience Task Force recommendations to manage psychosocial risks, optimise well-being, and reduce burnout in oncology.

Self-perceived cognitive impairment in the first year after breast cancer and the identification of at-risk patients.

Moderators of exercise effects on self-reported cognitive functioning in cancer survivors: an individual participant data meta-analysis.

Supervised, structured and individualized exercise in metastatic breast cancer: a randomized controlled trial.

Future of Multidisciplinary Team in the Context of Adaptive Therapy.

Evaluating the effect of higher Monte Carlo statistical uncertainties on accumulated doses after daily adaptive fractionated radiotherapy in prostate cancer.

Efficacy of TIL therapy in advanced cutaneous melanoma in the current immuno-oncology era: updated systematic review and meta-analysis.

Activity of Lutetium-177 Prostate-specific Membrane Antigen and Determinants of Outcomes in Patients with Metastatic Castration-resistant Prostate Cancer Previously Treated with Cabazitaxel: The PACAP Study.

Cancer drug-tolerant persister cells: from biological questions to clinical opportunities.

A combination of protein phosphatase 2A inhibition and checkpoint immunotherapy: a perfect storm.

Factors for a broad technology assessment of comprehensive genomic profiling in advanced cancer, a systematic review.

Correction to: Dysphagia After Total Laryngectomy: An Exploratory Study and Clinical Phase II Rehabilitation Trial with the Novel Swallowing Exercise Aid (SEA 2.0).

Associations of night shift work with weight gain among female nurses in The Netherlands: results of a prospective cohort study.

Incorporating patient-specific information for the development of rectal tumor auto-segmentation models for online adaptive magnetic resonance Image-guided radiotherapy.

Characteristics and clinical outcomes of breast cancer in young BRCA carriers according to tumor histology.

The Innate Immune Landscape of dMMR/MSI Cancers Predicts the Outcome of Nivolumab Treatment: Results from the Drug Rediscovery Protocol.

Recurrence of breast cancer after reconstruction with macro-textured silicone breast implants: a retrospective cohort study.

ADARp150 counteracts whole genome duplication.

Macrophage-mediated myelin recycling fuels brain cancer malignancy.

Correction: Interventional solutions for post‑surgical problems: a lymphatic leaks review.

Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.

Nucleolus and centromere Tyramide Signal Amplification-Seq reveals variable localization of heterochromatin in different cell types.

mRNA-1273 vaccination induces polyfunctional memory CD4 and CD8 T cell responses in patients with solid cancers undergoing immunotherapy or/and chemotherapy.

Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.

High-dose chemotherapy for patients with stage III breast cancer with homologous recombination deficiency: a discrete choice experiment among healthcare providers.

Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8+ T cells.

High expression of phosphoglycerate dehydrogenase predicts poor outcome in patients with high-grade serous ovarian cancer.

Co-observation of germline pathogenic variants in breast cancer predisposition genes: Results from analysis of the BRIDGES sequencing dataset.

Analysis of more than 400,000 women provides case-control evidence for BRCA1 and BRCA2 variant classification.

Efficacy of Pembrolizumab and Biomarker Analysis in Patients with WGS-Based Intermediate to High Tumor Mutational Load: Results from the Drug Rediscovery Protocol.

Maximizing Treatment Opportunities: Assessing Protocol Waivers' Impact on Safety and Outcome in the Drug Rediscovery Protocol.

The role of drug efflux and uptake transporters in the plasma pharmacokinetics and tissue disposition of morphine and its main metabolites.

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Combination anti-PD-1 and anti-CTLA-4 therapy generates waves of clonal responses that include progenitor-exhausted CD8⁺ T cells.