Publications

Nature communications

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

22-06-2024

iScience

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

21-06-2024

Scientific reports

Cox proportional hazards regression in small studies of predictive biomarkers.

20-06-2024

NPJ digital medicine

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

20-06-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

20-06-2024

Cell reports. Medicine

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

18-06-2024

The British journal of radiology

Imaging in the era of risk-adapted treatment in colon cancer.

18-06-2024

Journal of pharmaceutical and biomedical analysis

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

15-06-2024

Nature communications

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

12-06-2024

Cancer cell

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

10-06-2024

The New England journal of medicine

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

06-06-2024

Molecular cancer

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

04-06-2024

bioRxiv : the preprint server for biology

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

03-06-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

ABCB1 attenuates brain exposure to the KRAS^G12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Common Sense Oncology: Equity, Value, and Outcomes That Matter.

01-06-2024

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Adoptive Cell Therapy for Solid Tumors: Current Status in Melanoma and Next-Generation Therapies.

01-06-2024

FEBS letters

Decoding microtubule detyrosination: enzyme families, structures, and functional implications.

01-06-2024

Diseases of the colon and rectum

An International Expert-Based Consensus on the Definition of a Clinical Near-Complete Response After Neoadjuvant (Chemo)radiotherapy for Rectal Cancer.

01-06-2024

European radiology

Importance and evolution of split scar sign.

01-06-2024

Journal of biomedical optics

Deformable multi-modal image registration for the correlation between optical measurements and histology images.

01-06-2024

JCO clinical cancer informatics

Improving Diagnosis and Care for Patients With Sarcoma: Do Real-World General Practitioners Data and Prospective Data Collections Have a Place Next to Clinical Trials?

01-06-2024

Advances in radiation oncology

Evaluation of Deep Learning Clinical Target Volumes Auto-Contouring for Magnetic Resonance Imaging-Guided Online Adaptive Treatment of Rectal Cancer.

01-06-2024

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

Impact of the new rectal cancer definition on multimodality treatment and interhospital variability: Results from a nationwide cross-sectional study.

01-06-2024

European urology

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.

01-06-2024

European journal of radiology open

Reproducing RECIST lesion selection via machine learning: Insights into intra and inter-radiologist variation.

01-06-2024

Journal of molecular biology

MutL Activates UvrD by Interaction Between the MutL C-terminal Domain and the UvrD 2B Domain.

01-06-2024

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.

01-06-2024

ESMO open

Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes.

01-06-2024

Nature reviews. Molecular cell biology

Seeing transcription in real time.

01-06-2024

Journal of cancer survivorship : research and practice

Subgroups of cognitively affected and unaffected breast cancer survivors after chemotherapy: a data-driven approach.

01-06-2024

Breast (Edinburgh, Scotland)

Radiological, pathological and surgical outcomes after neoadjuvant endocrine treatment in patients with ER-positive/HER2-negative breast cancer with a clinical high risk and a low-risk 70-gene signature.

01-06-2024

Therapeutic drug monitoring

Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication.

01-06-2024

Current opinion in genetics & development

Attraction and disruption: how loop extrusion and compartmentalisation shape the nuclear genome.

01-06-2024

Investigative radiology

How Does Target Lesion Selection Affect RECIST? A Computer Simulation Study.

01-06-2024

Molecular oncology

Academia and society should join forces to make anti-cancer treatments more affordable.

01-06-2024

ESMO real world data and digital oncology

Health-related quality of life in patients with gastrointestinal stromal tumor: data from a real-world cohort compared with a normative population.

01-06-2024

Oncogene

Molecular mechanisms of non-genetic aberrant peptide production in cancer.

01-06-2024

AJR. American journal of roentgenology

Beyond the AJR: A Breakthrough in the Use of Artificial Intelligence for Mammography in Screening for Breast Cancer.

01-06-2024

The Journal of pathology

Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting.

01-06-2024

Analytical biochemistry

An LC-MS/MS-based method for the simultaneous quantification of melatonin, cortisol and cortisone in saliva.

01-06-2024

Cancer medicine

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors.

01-06-2024

European journal of cancer (Oxford, England : 1990)

European clinical practice guidelines for the definition, diagnosis, and treatment of oligometastatic esophagogastric cancer (OMEC-4).

01-06-2024

Gastroenterology

Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs.

01-06-2024

Journal of genetic counseling

Does a proactive procedure lead to a higher uptake of predictive testing in families with a pathogenic BRCA1/BRCA2 variant? A family cancer clinic evaluation.

01-06-2024

Annals of epidemiology

Strategies to increase survey participation: A randomized controlled study in a population of breast cancer survivors.

01-06-2024

European radiology

Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation.

01-06-2024

Cytotherapy

High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant.

01-06-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment.

01-06-2024

European journal of cancer (Oxford, England : 1990)

Oncological outcomes after a pathological complete response following total neoadjuvant therapy or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial.

01-06-2024

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma.

01-06-2024

Widespread chromatin context-dependencies of DNA double-strand break repair proteins.

Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies.

Cox proportional hazards regression in small studies of predictive biomarkers.

PatchSorter: a high throughput deep learning digital pathology tool for object labeling.

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

The impact of ATP-binding cassette transporters in the diseased brain: Context matters.

Imaging in the era of risk-adapted treatment in colon cancer.

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

UBE2D3 facilitates NHEJ by orchestrating ATM signalling through multi-level control of RNF168.

The case for therapeutic overactivation of oncogenic signaling as a potential cancer treatment strategy.

Neoadjuvant Immunotherapy in Locally Advanced Mismatch Repair-Deficient Colon Cancer.

Diversifying the anthracycline class of anti-cancer drugs identifies aclarubicin for superior survival of acute myeloid leukemia patients.

Automated classification of cellular expression in multiplexed imaging data with Nimbus.

ABCB1 attenuates brain exposure to the KRASG12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.

Common Sense Oncology: Equity, Value, and Outcomes That Matter.

Adoptive Cell Therapy for Solid Tumors: Current Status in Melanoma and Next-Generation Therapies.

Decoding microtubule detyrosination: enzyme families, structures, and functional implications.

An International Expert-Based Consensus on the Definition of a Clinical Near-Complete Response After Neoadjuvant (Chemo)radiotherapy for Rectal Cancer.

Importance and evolution of split scar sign.

Deformable multi-modal image registration for the correlation between optical measurements and histology images.

Improving Diagnosis and Care for Patients With Sarcoma: Do Real-World General Practitioners Data and Prospective Data Collections Have a Place Next to Clinical Trials?

Evaluation of Deep Learning Clinical Target Volumes Auto-Contouring for Magnetic Resonance Imaging-Guided Online Adaptive Treatment of Rectal Cancer.

Impact of the new rectal cancer definition on multimodality treatment and interhospital variability: Results from a nationwide cross-sectional study.

Health-related Quality of Life in Patients with Previously Treated Advanced Urothelial Carcinoma from EV-301: A Phase 3 Trial of Enfortumab Vedotin Versus Chemotherapy.

Reproducing RECIST lesion selection via machine learning: Insights into intra and inter-radiologist variation.

MutL Activates UvrD by Interaction Between the MutL C-terminal Domain and the UvrD 2B Domain.

Interplay of OATP1A/1B/2B1 uptake transporters and ABCB1 and ABCG2 efflux transporters in the handling of bilirubin and drugs.

Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes.

Seeing transcription in real time.

Subgroups of cognitively affected and unaffected breast cancer survivors after chemotherapy: a data-driven approach.

Radiological, pathological and surgical outcomes after neoadjuvant endocrine treatment in patients with ER-positive/HER2-negative breast cancer with a clinical high risk and a low-risk 70-gene signature.

Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication.

Attraction and disruption: how loop extrusion and compartmentalisation shape the nuclear genome.

How Does Target Lesion Selection Affect RECIST? A Computer Simulation Study.

Academia and society should join forces to make anti-cancer treatments more affordable.

Health-related quality of life in patients with gastrointestinal stromal tumor: data from a real-world cohort compared with a normative population.

Molecular mechanisms of non-genetic aberrant peptide production in cancer.

Beyond the AJR: A Breakthrough in the Use of Artificial Intelligence for Mammography in Screening for Breast Cancer.

Polyketide synthase positive Escherichia coli one-time measurement in stool is not informative of colorectal cancer risk in a screening setting.

An LC-MS/MS-based method for the simultaneous quantification of melatonin, cortisol and cortisone in saliva.

Treatment patterns and survival outcomes of patients admitted to the intensive care unit due to immune-related adverse events of immune checkpoint inhibitors.

European clinical practice guidelines for the definition, diagnosis, and treatment of oligometastatic esophagogastric cancer (OMEC-4).

Dual Inhibition of CDK4/6 and XPO1 Induces Senescence With Acquired Vulnerability to CRBN-Based PROTAC Drugs.

Does a proactive procedure lead to a higher uptake of predictive testing in families with a pathogenic BRCA1/BRCA2 variant? A family cancer clinic evaluation.

Strategies to increase survey participation: A randomized controlled study in a population of breast cancer survivors.

Independent validation of CT radiomics models in colorectal liver metastases: predicting local tumour progression after ablation.

High-dose individualized antithymocyte globulin with therapeutic drug monitoring in high-risk cord blood transplant.

Prognostic significance of MRI-detected extramural venous invasion according to grade and response to neo-adjuvant treatment in locally advanced rectal cancer A national cohort study after radiologic training and reassessment.

Oncological outcomes after a pathological complete response following total neoadjuvant therapy or chemoradiotherapy for high-risk locally advanced rectal cancer in the RAPIDO trial.

Doxorubicin Exposure and Breast Cancer Risk in Survivors of Adolescent and Adult Hodgkin Lymphoma.

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ABCB1 attenuates brain exposure to the KRAS^G12C inhibitor opnurasib whereas binding to mouse carboxylesterase 1c influences its plasma exposure.