Publications

Cancers

Cell-Free Circulating (Tumor) DNA before Surgery as a Prognostic Factor in Non-Metastatic Colorectal Cancer: A Systematic Review.

29-04-2022

NPJ breast cancer

Spatial interplay of lymphocytes and fibroblasts in estrogen receptor-positive HER2-negative breast cancer.

28-04-2022

Journal of medicinal chemistry

Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators.

28-04-2022

Life (Basel, Switzerland)

Use of Image-Guided Surgical Navigation during Resection of Locally Recurrent Rectal Cancer.

27-04-2022

Science translational medicine

Addition of interleukin-2 overcomes resistance to neoadjuvant CTLA4 and PD1 blockade in ex vivo patient tumors.

27-04-2022

International journal of molecular sciences

Functional Screen for microRNAs Suppressing Anchorage-Independent Growth in Human Cervical Cancer Cells.

26-04-2022

Practical radiation oncology

Bronchial Stenosis in Central Pulmonary Tumors Treated With Stereotactic Body Radiation Therapy.

23-04-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Outcome of Patients With an Ultralow-Risk 70-Gene Signature in the MINDACT Trial.

20-04-2022

Health and quality of life outcomes

'I thought I had fibroids, and now I don't': a mixed method study on health-related quality of life in uterine sarcoma patients.

20-04-2022

Nature communications

A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways.

19-04-2022

Molecular & cellular oncology

Filling in the gaps in PARP inhibitor-induced synthetic lethality.

15-04-2022

International journal of general medicine

Estimating VO_2peak in 18-90 Year-Old Adults: Development and Validation of the FitMáx©-Questionnaire.

13-04-2022

Blood advances

Fludarabine exposure predicts outcome after CD19 CAR T-cell therapy in children and young adults with acute leukemia.

12-04-2022

Sarcoma

Prognostic Significance of Bone Metastasis in Soft Tissue Sarcoma Patients Receiving Palliative Systemic Therapy: An Explorative, Retrospective Pooled Analysis of the EORTC-Soft Tissue and Bone Sarcoma Group (STBSG) Database.

12-04-2022

Journal of the National Cancer Institute

Oral Contraceptive Use in BRCA1 and BRCA2 Mutation Carriers: Absolute Cancer Risks and Benefits.

11-04-2022

Journal of the National Cancer Institute

Next Step for Global Adolescent and Young Adult Oncology: A Core Patient-Centered Outcome Set.

11-04-2022

Nature communications

Ubiquitin ligase STUB1 destabilizes IFNγ-receptor complex to suppress tumor IFNγ signaling.

08-04-2022

Key

Communications biology

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.

08-04-2022

BMC cancer

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

08-04-2022

Nature communications

Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial.

06-04-2022

Cell reports

FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer.

05-04-2022

Cancers

Health-Related Quality of Life and Side Effects in Gastrointestinal Stromal Tumor (GIST) Patients Treated with Tyrosine Kinase Inhibitors: A Systematic Review of the Literature.

05-04-2022

Journal of clinical medicine

T_1ρ for Radiotherapy Treatment Response Monitoring in Rectal Cancer Patients: A Pilot Study.

02-04-2022

Nature medicine

Delivering precision oncology to patients with cancer.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

01-04-2022

Virchows Archiv : an international journal of pathology

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: A multicentre observational cohort study (eQuiPe).

01-04-2022

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

01-04-2022

European journal of radiology

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

01-04-2022

Clinical genitourinary cancer

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

01-04-2022

Molecular cancer therapeutics

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

01-04-2022

Pharmacological research

ABCB1 limits brain exposure of the KRAS^G12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Male breast cancer after childhood cancer: Systematic review and analyses in the PanCareSurFup cohort.

01-04-2022

European journal of nuclear medicine and molecular imaging

The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection.

01-04-2022

Breast care (Basel, Switzerland)

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

01-04-2022

European journal of cancer (Oxford, England : 1990)

The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC.

01-04-2022

Medicine and science in sports and exercise

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer.

01-04-2022

Key

Pharmacological research

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.

01-04-2022

Clinical pharmacokinetics

Correction to: Unbound Plasma, Total Plasma and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-04-2022

Cancer discovery

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.

01-04-2022

Magma (New York, N.Y.)

Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses.

01-04-2022

Nature biotechnology

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

01-04-2022

Nature

Nonlinear control of transcription through enhancer-promoter interactions.

01-04-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

01-04-2022

Pharmaceutical research

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.

01-04-2022

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Neoadjuvant Immunotherapy: Leveraging the Immune System to Treat Early-Stage Disease.

01-04-2022

Palliative medicine

Sexual health and closeness in couples coping with advanced cancer: Results of a multicenter observational study (eQuiPe).

01-04-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.

01-04-2022

Clinical breast cancer

Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?

01-04-2022

European urology

Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.

01-04-2022