Publications

Molecular biology of the cell

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

15-05-2015

Sensors (Basel, Switzerland)

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

12-05-2015

Scientific reports

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

12-05-2015

The EMBO journal

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.

12-05-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Molecular profiling is rather likely to be cost effective.

10-05-2015

Lancet (London, England)

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.

09-05-2015

Journal of applied clinical medical physics

Portal dosimetry in wedged beams.

08-05-2015

Journal of medical Internet research

Response rates for patient-reported outcomes using web-based versus paper questionnaires: comparison of two invitational methods in older colorectal cancer patients.

07-05-2015

Cell

Prospective derivation of a living organoid biobank of colorectal cancer patients.

07-05-2015

BMC cancer

Treatment strategies in colorectal cancer patients with initially unresectable liver-only metastases, a study protocol of the randomised phase 3 CAIRO5 study of the Dutch Colorectal Cancer Group (DCCG).

06-05-2015

Journal of the National Cancer Institute

Prediction of breast cancer risk based on profiling with common genetic variants.

01-05-2015

EMBO reports

Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells.

01-05-2015

Cancer treatment reviews

Variability in bioavailability of small molecular tyrosine kinase inhibitors.

01-05-2015

Radiology

Multimodal Surgical Guidance during Sentinel Node Biopsy for Melanoma: Combined Gamma Tracing and Fluorescence Imaging of the Sentinel Node through Use of the Hybrid Tracer Indocyanine Green-(99m)Tc-Nanocolloid.

01-05-2015

Human reproduction (Oxford, England)

Melanoma risk after ovarian stimulation for in vitro fertilization.

01-05-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Prostate tumor delineation using multiparametric magnetic resonance imaging: Inter-observer variability and pathology validation.

01-05-2015

European journal of human genetics : EJHG

Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population.

01-05-2015

Journal of the National Cancer Institute

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction.

01-05-2015

Pigment cell & melanoma research

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

01-05-2015

Journal of the National Cancer Institute

Identification of novel genetic markers of breast cancer survival.

01-05-2015

Diabetologia

Impact of cancer on adherence to glucose-lowering drug treatment in individuals with diabetes.

01-05-2015

Radiology

Diagnostic Performance of Dedicated Axillary T2- and Diffusion-weighted MR Imaging for Nodal Staging in Breast Cancer.

01-05-2015

Expert opinion on biological therapy

Enhancer-associated RNAs as therapeutic targets.

01-05-2015

Acta oncologica (Stockholm, Sweden)

High levels of physical activity are associated with lower levels of fatigue among lymphoma patients: Results from the longitudinal PROFILES registry.

01-05-2015

Molecular oncology

Hurdles on the road to personalized medicine.

01-05-2015

International journal of radiation oncology, biology, physics

Simple method to estimate mean heart dose from Hodgkin lymphoma radiation therapy according to simulation X-rays.

01-05-2015

British journal of clinical pharmacology

Integrated semi-physiological pharmacokinetic model for both sunitinib and its active metabolite SU12662.

01-05-2015

BioMed research international

Corrigendum to "Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy".

30-04-2015

Acta oncologica (Stockholm, Sweden)

A phase I study on the combination of neoadjuvant radiotherapy plus pazopanib in patients with locally advanced soft tissue sarcoma of the extremities.

30-04-2015

BMC cancer

Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer: design of a multicenter, randomized controlled trial.

28-04-2015

Breast cancer research : BCR

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.

25-04-2015

Breast cancer research : BCR

Common germline polymorphisms associated with breast cancer-specific survival.

22-04-2015

Immunity

Thinking outside the gate: single-cell assessments in multiple dimensions.

21-04-2015

Immunity

Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response.

21-04-2015

Nucleic acids research

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference.

20-04-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer.

20-04-2015

Oncotarget

TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation.

20-04-2015

PloS one

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity.

16-04-2015

Bioscience reports

Identification of signalling cascades involved in red blood cell shrinkage and vesiculation.

16-04-2015

British journal of cancer

HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53.

14-04-2015

Oncotarget

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients.

10-04-2015

BMC research notes

Development of an instrument to analyze organizational characteristics in multidisciplinary care pathways; the case of colorectal cancer.

09-04-2015

Journal of translational medicine

Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy.

09-04-2015

NeuroImage. Clinical

Multimodal MRI and cognitive function in patients with breast cancer prior to adjuvant treatment--the role of fatigue.

07-04-2015

PloS one

Measuring the outcome of biomedical research: a systematic literature review.

04-04-2015

Science (New York, N.Y.)

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

03-04-2015

Science (New York, N.Y.)

Neoantigens in cancer immunotherapy.

03-04-2015

Molecular cell

Make them, break them, and catch them: studying rare ubiquitin chains.

02-04-2015

PloS one

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.

02-04-2015

Nederlands tijdschrift voor geneeskunde

[Hypofractionated adjuvant radiotherapy for breast cancer: no signs of increased risk of cardiotoxicity].

02-04-2015

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.

Molecular profiling is rather likely to be cost effective.

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.

Portal dosimetry in wedged beams.

Response rates for patient-reported outcomes using web-based versus paper questionnaires: comparison of two invitational methods in older colorectal cancer patients.

Prospective derivation of a living organoid biobank of colorectal cancer patients.

Treatment strategies in colorectal cancer patients with initially unresectable liver-only metastases, a study protocol of the randomised phase 3 CAIRO5 study of the Dutch Colorectal Cancer Group (DCCG).

Prediction of breast cancer risk based on profiling with common genetic variants.

Nuclear lamins are not required for lamina-associated domain organization in mouse embryonic stem cells.

Variability in bioavailability of small molecular tyrosine kinase inhibitors.

Multimodal Surgical Guidance during Sentinel Node Biopsy for Melanoma: Combined Gamma Tracing and Fluorescence Imaging of the Sentinel Node through Use of the Hybrid Tracer Indocyanine Green-(99m)Tc-Nanocolloid.

Melanoma risk after ovarian stimulation for in vitro fertilization.

Prostate tumor delineation using multiparametric magnetic resonance imaging: Inter-observer variability and pathology validation.

Evaluation of the Dutch BRCA1/2 clinical genetic center referral criteria in an unselected early breast cancer population.

Breast cancer risk after salpingo-oophorectomy in healthy BRCA1/2 mutation carriers: revisiting the evidence for risk reduction.

Cooperative induction of apoptosis in NRAS mutant melanoma by inhibition of MEK and ROCK.

Identification of novel genetic markers of breast cancer survival.

Impact of cancer on adherence to glucose-lowering drug treatment in individuals with diabetes.

Diagnostic Performance of Dedicated Axillary T2- and Diffusion-weighted MR Imaging for Nodal Staging in Breast Cancer.

Enhancer-associated RNAs as therapeutic targets.

High levels of physical activity are associated with lower levels of fatigue among lymphoma patients: Results from the longitudinal PROFILES registry.

Hurdles on the road to personalized medicine.

Simple method to estimate mean heart dose from Hodgkin lymphoma radiation therapy according to simulation X-rays.

Integrated semi-physiological pharmacokinetic model for both sunitinib and its active metabolite SU12662.

Corrigendum to "Semiphysiological versus Empirical Modelling of the Population Pharmacokinetics of Free and Total Cefazolin during Pregnancy".

A phase I study on the combination of neoadjuvant radiotherapy plus pazopanib in patients with locally advanced soft tissue sarcoma of the extremities.

Internet-based cognitive behavioral therapy for sexual dysfunctions in women treated for breast cancer: design of a multicenter, randomized controlled trial.

An original phylogenetic approach identified mitochondrial haplogroup T1a1 as inversely associated with breast cancer risk in BRCA2 mutation carriers.

Common germline polymorphisms associated with breast cancer-specific survival.

Thinking outside the gate: single-cell assessments in multiple dimensions.

Complement is a central mediator of radiotherapy-induced tumor-specific immunity and clinical response.

Advances in CRISPR-Cas9 genome engineering: lessons learned from RNA interference.

PIK3CA mutations are associated with decreased benefit to neoadjuvant human epidermal growth factor receptor 2-targeted therapies in breast cancer.

TRPM7 maintains progenitor-like features of neuroblastoma cells: implications for metastasis formation.

Fourth-generation epac-based FRET sensors for cAMP feature exceptional brightness, photostability and dynamic range: characterization of dedicated sensors for FLIM, for ratiometry and with high affinity.

Identification of signalling cascades involved in red blood cell shrinkage and vesiculation.

HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53.

The SNP rs6500843 in 16p13.3 is associated with survival specifically among chemotherapy-treated breast cancer patients.

Development of an instrument to analyze organizational characteristics in multidisciplinary care pathways; the case of colorectal cancer.

Increased levels of choline metabolites are an early marker of docetaxel treatment response in BRCA1-mutated mouse mammary tumors: an assessment by ex vivo proton magnetic resonance spectroscopy.

Multimodal MRI and cognitive function in patients with breast cancer prior to adjuvant treatment--the role of fatigue.

Measuring the outcome of biomedical research: a systematic literature review.

Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer.

Neoantigens in cancer immunotherapy.

Make them, break them, and catch them: studying rare ubiquitin chains.

Assessing associations between the AURKA-HMMR-TPX2-TUBG1 functional module and breast cancer risk in BRCA1/2 mutation carriers.

[Hypofractionated adjuvant radiotherapy for breast cancer: no signs of increased risk of cardiotoxicity].

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