Publications

EMBO molecular medicine

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

01-09-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

01-09-2015

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

An interactive portal to empower cancer survivors: a qualitative study on user expectations.

01-09-2015

Pharmacoepidemiology and drug safety

Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review.

01-09-2015

British journal of cancer

Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.

01-09-2015

JAMA otolaryngology-- head & neck surgery

Prediction of Hearing Loss Due to Cisplatin Chemoradiotherapy.

01-09-2015

eLife

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

01-09-2015

Veterinary and comparative oncology

Determination of platinum surface contamination in veterinary and human oncology centres using inductively coupled plasma mass spectrometry.

01-09-2015

Cancers

Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review.

28-08-2015

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Minimal residual disease in cancer therapy--Small things make all the difference.

27-08-2015

Nucleic acids research

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

18-08-2015

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry.

15-08-2015

Nederlands tijdschrift voor geneeskunde

[Shared decision-making becoming increasingly important].

15-08-2015

Cancer

Age-related differences in quality of life among patients with diffuse large B-cell lymphoma.

15-08-2015

BMC cancer

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

14-08-2015

Breast cancer research : BCR

Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.

05-08-2015

Trends in biochemical sciences

Layers of DUB regulation.

01-08-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Tumour delineation in oesophageal cancer - A prospective study of delineation in PET and CT with and without endoscopically placed clip markers.

01-08-2015

European journal of cancer (Oxford, England : 1990)

Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - The LORD study.

01-08-2015

Breast cancer research and treatment

Fat/water ratios measured with diffuse reflectance spectroscopy to detect breast tumor boundaries.

01-08-2015

Lancet (London, England)

Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.

01-08-2015

Clinical breast cancer

Tailored Tamoxifen Treatment for Breast Cancer Patients: A Perspective.

01-08-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiation-induced dose-dependent changes of the spleen following postoperative chemoradiotherapy for gastric cancer.

01-08-2015

Dysphagia

Effects of Strengthening Exercises on Swallowing Musculature and Function in Senior Healthy Subjects: a Prospective Effectiveness and Feasibility Study.

01-08-2015

Pain

Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2⁺ breast cancer.

01-08-2015

British journal of clinical pharmacology

Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function.

01-08-2015

Genes & development

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

01-08-2015

Breast cancer research and treatment

The prognostic value of the neoadjuvant response index in triple-negative breast cancer: validation and comparison with pathological complete response as outcome measure.

01-08-2015

European urology

Reply to Eliezer M. Van Allen, Levi A. Garraway and Jonathan E. Rosenberg's Letter to the Editor re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014.

01-08-2015

The Lancet. Oncology

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.

01-08-2015

Nature reviews. Cancer

Evolving synergistic combinations of targeted immunotherapies to combat cancer.

01-08-2015

Breast (Edinburgh, Scotland)

Early stage cost-effectiveness analysis of a BRCA1-like test to detect triple negative breast cancers responsive to high dose alkylating chemotherapy.

01-08-2015

The international journal of biochemistry & cell biology

Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome.

01-08-2015

Clinical pharmacokinetics

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

01-08-2015

Biochimica et biophysica acta

C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake.

01-08-2015

European urology

Re: Alessandro Volpe, Kamran Ahmed, Prokar Dasgupta, et al. Pilot Validation Study of the European Association of Urology Robotic Training Curriculum. Eur Urol 2015;68:292-9.

01-08-2015

Molecular oncology

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.

01-08-2015

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model.

01-08-2015

Radiation oncology (London, England)

Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer.

30-07-2015

Health and quality of life outcomes

Validation of the French translation-adaptation of the impact of cancer questionnaire version 2 (IOCv2) in a breast cancer survivor population.

29-07-2015

British journal of cancer

Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.

28-07-2015

British journal of cancer

Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?

28-07-2015

Science translational medicine

Optimizing sharing of hospital biobank samples.

22-07-2015

International journal of clinical and experimental pathology

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

21-07-2015

Ecancermedicalscience

Staff perceptions of change resulting from participation in a European cancer accreditation programme: a snapshot from eight cancer centres.

17-07-2015

PloS one

Co-Orientation: Quantifying Simultaneous Co-Localization and Orientational Alignment of Filaments in Light Microscopy.

15-07-2015

Genes & development

Origins, genetic landscape, and emerging therapies of small cell lung cancer.

15-07-2015

Cancer cell

Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

13-07-2015

eLife

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.

11-07-2015

PloS one

Studying Hospitalizations and Mortality in the Netherlands: Feasible and Valid Using Two-Step Medical Record Linkage with Nationwide Registers.

07-07-2015

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

An interactive portal to empower cancer survivors: a qualitative study on user expectations.

Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review.

Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.

Prediction of Hearing Loss Due to Cisplatin Chemoradiotherapy.

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

Determination of platinum surface contamination in veterinary and human oncology centres using inductively coupled plasma mass spectrometry.

Feasibility of Primary Tumor Culture Models and Preclinical Prediction Assays for Head and Neck Cancer: A Narrative Review.

Minimal residual disease in cancer therapy--Small things make all the difference.

The de-ubiquitylating enzymes USP26 and USP37 regulate homologous recombination by counteracting RAP80.

Quantification of miltefosine in peripheral blood mononuclear cells by high-performance liquid chromatography-tandem mass spectrometry.

[Shared decision-making becoming increasingly important].

Age-related differences in quality of life among patients with diffuse large B-cell lymphoma.

Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13.

Treatment with insulin (analogues) and breast cancer risk in diabetics; a systematic review and meta-analysis of in vitro, animal and human evidence.

Layers of DUB regulation.

Tumour delineation in oesophageal cancer - A prospective study of delineation in PET and CT with and without endoscopically placed clip markers.

Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - The LORD study.

Fat/water ratios measured with diffuse reflectance spectroscopy to detect breast tumor boundaries.

Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.

Tailored Tamoxifen Treatment for Breast Cancer Patients: A Perspective.

Radiation-induced dose-dependent changes of the spleen following postoperative chemoradiotherapy for gastric cancer.

Effects of Strengthening Exercises on Swallowing Musculature and Function in Senior Healthy Subjects: a Prospective Effectiveness and Feasibility Study.

Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2⁺ breast cancer.

Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function.

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

The prognostic value of the neoadjuvant response index in triple-negative breast cancer: validation and comparison with pathological complete response as outcome measure.

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.

Evolving synergistic combinations of targeted immunotherapies to combat cancer.

Early stage cost-effectiveness analysis of a BRCA1-like test to detect triple negative breast cancers responsive to high dose alkylating chemotherapy.

Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome.

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake.

Re: Alessandro Volpe, Kamran Ahmed, Prokar Dasgupta, et al. Pilot Validation Study of the European Association of Urology Robotic Training Curriculum. Eur Urol 2015;68:292-9.

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.

Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model.

Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer.

Validation of the French translation-adaptation of the impact of cancer questionnaire version 2 (IOCv2) in a breast cancer survivor population.

Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.

Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?

Optimizing sharing of hospital biobank samples.

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

Staff perceptions of change resulting from participation in a European cancer accreditation programme: a snapshot from eight cancer centres.

Co-Orientation: Quantifying Simultaneous Co-Localization and Orientational Alignment of Filaments in Light Microscopy.

Origins, genetic landscape, and emerging therapies of small cell lung cancer.

Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.

Studying Hospitalizations and Mortality in the Netherlands: Feasible and Valid Using Two-Step Medical Record Linkage with Nationwide Registers.

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