Publications

Oncoimmunology

Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma.

01-08-2012

British journal of clinical pharmacology

Model-based treatment optimization of a novel VEGFR inhibitor.

01-08-2012

Investigational new drugs

Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies.

01-08-2012

Diabetologia

Disease-specific mortality among stage I-III colorectal cancer patients with diabetes: a large population-based analysis.

01-08-2012

PLoS genetics

A key role for Chd1 in histone H3 dynamics at the 3' ends of long genes in yeast.

19-07-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Determination of NVP-BEZ235, a dual PI3K and mTOR inhibitor, in human and mouse plasma and in mouse tissue homogenates by reversed-phase high-performance liquid chromatography with fluorescence detection.

15-07-2012

The Journal of biological chemistry

Structural characterization of binding mode of smoking cessation drugs to nicotinic acetylcholine receptors through study of ligand complexes with acetylcholine-binding protein.

06-07-2012

Head & neck

Five-year quality of life results of the randomized clinical phase III (RADPLAT) trial, comparing concomitant intra-arterial versus intravenous chemoradiotherapy in locally advanced head and neck cancer.

01-07-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Pre-treatment imaging and pathology characteristics of invasive breast cancers of limited extent: potential relevance for MRI-guided localized therapy.

01-07-2012

Oncoimmunology

TIL therapy broadens the tumor-reactive CD8(+) T cell compartment in melanoma patients.

01-07-2012

European journal of nuclear medicine and molecular imaging

Concomitant radio- and fluorescence-guided sentinel lymph node biopsy in squamous cell carcinoma of the oral cavity using ICG-(99m)Tc-nanocolloid.

01-07-2012

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Relationship between intraprostatic tracer deposits and sentinel lymph node mapping in prostate cancer patients.

01-07-2012

European journal of cancer (Oxford, England : 1990)

Five-year quality of life of endometrial cancer patients treated in the randomised Post Operative Radiation Therapy in Endometrial Cancer (PORTEC-2) trial and comparison with norm data.

01-07-2012

Drug metabolism and disposition: the biological fate of chemicals

Metabolite profiling of bendamustine in urine of cancer patients after administration of [14C]bendamustine.

01-07-2012

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Comparing the hybrid fluorescent-radioactive tracer indocyanine green-99mTc-nanocolloid with 99mTc-nanocolloid for sentinel node identification: a validation study using lymphoscintigraphy and SPECT/CT.

01-07-2012

PloS one

Carbonic anhydrase 5 regulates acid-base homeostasis in zebrafish.

30-06-2012

The oncologist

Concise drug review: pazopanib and axitinib.

27-06-2012

Breast cancer research and treatment

Importance of highly selective LC-MS/MS analysis for the accurate quantification of tamoxifen and its metabolites: focus on endoxifen and 4-hydroxytamoxifen.

01-06-2012

Biochemical Society transactions

The role of UBL domains in ubiquitin-specific proteases.

01-06-2012

Archives of otolaryngology--head & neck surgery

Total laryngectomy for a dysfunctional larynx after (chemo)radiotherapy.

01-06-2012

Development (Cambridge, England)

The Polycomb group protein Ring1b is essential for pectoral fin development.

01-06-2012

Cancer discovery

Tracking evolution of BRCA1-associated breast cancer.

01-06-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Adaptive radiotherapy for long course neo-adjuvant treatment of rectal cancer.

01-06-2012

Annals of surgical oncology

Feasibility of sentinel node biopsy in head and neck melanoma using a hybrid radioactive and fluorescent tracer.

01-06-2012

Cancer chemotherapy and pharmacology

Decitabine triphosphate levels in peripheral blood mononuclear cells from patients receiving prolonged low-dose decitabine administration: a pilot study.

01-06-2012

Medical physics

TU-E-BRCD-01: The Emerging Role of Image-Guidance for Breast Radiotherapy.

01-06-2012

Current oncology reports

Immunological heterogeneity of the RCC microenvironment: do targeted therapies influence immune response?

01-06-2012

Nederlands tijdschrift voor geneeskunde

[Consent for the secondary use of human residual tissue: the patient is best served by an 'opting-out' procedure].

24-05-2012

Physics in medicine and biology

Image navigation as a means to expand the boundaries of fluorescence-guided surgery.

21-05-2012

Journal of palliative care

Severe cannabinoid intoxication in a patient with non-small-cell lung cancer.

16-05-2012

Genes & development

Abrogation of BRAFV600E-induced senescence by PI3K pathway activation contributes to melanomagenesis.

15-05-2012

PloS one

GFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumors.

11-05-2012

PloS one

Self-reported physical activity: its correlates and relationship with health-related quality of life in a large cohort of colorectal cancer survivors.

09-05-2012

British journal of cancer

A phase I study of E7080, a multitargeted tyrosine kinase inhibitor, in patients with advanced solid tumours.

08-05-2012

Cancer research

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.

01-05-2012

The Journal of clinical investigation

Akt-mediated phosphorylation of Bmi1 modulates its oncogenic potential, E3 ligase activity, and DNA damage repair activity in mouse prostate cancer.

01-05-2012

Psycho-oncology

Self-reported cognitive functioning in postmenopausal breast cancer patients before and during endocrine treatment: findings from the neuropsychological TEAM side-study.

01-05-2012

Cancer

Germline polymorphisms in patients with advanced nonsmall cell lung cancer receiving first-line platinum-gemcitabine chemotherapy: a prospective clinical study.

01-05-2012

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Irradiation induced modest changes in murine cardiac function despite progressive structural damage to the myocardium and microvasculature.

01-05-2012

Cell

The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.

27-04-2012

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of LC-MS/MS assays for the quantification of bendamustine and its metabolites in human plasma and urine.

15-04-2012

Cell cycle (Georgetown, Tex.)

Posttranslational control of telomere maintenance and the telomere damage response.

15-04-2012

The oncologist

Lapatinib for advanced or metastatic breast cancer.

06-04-2012

The Journal of pharmacology and experimental therapeutics

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) restrict brain accumulation of the active sunitinib metabolite N-desethyl sunitinib.

01-04-2012

Molecular biology of the cell

Phosphorylation of threonine 1736 in the C-terminal tail of integrin β4 contributes to hemidesmosome disassembly.

01-04-2012

Acta crystallographica. Section D, Biological crystallography

PDB_REDO: constructive validation, more than just looking for errors.

01-04-2012

Investigational new drugs

Restricted brain penetration of the tyrosine kinase inhibitor erlotinib due to the drug transporters P-gp and BCRP.

01-04-2012

Breast cancer research and treatment

Prediction of BRCA2-association in hereditary breast carcinomas using array-CGH.

01-04-2012

Acta oncologica (Stockholm, Sweden)

Scalp cooling for hair preservation and associated characteristics in 1411 chemotherapy patients - results of the Dutch Scalp Cooling Registry.

01-04-2012

General hospital psychiatry

Type D personality is associated with increased comorbidity burden and health care utilization among 3080 cancer survivors.

31-03-2012