Publications

Breast cancer research and treatment

The proportion of postmenopausal breast cancer cases in the Netherlands attributable to lifestyle-related risk factors.

01-07-2015

European journal of cancer (Oxford, England : 1990)

A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: the TRUSTS trial.

01-07-2015

British journal of cancer

Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma.

30-06-2015

mBio

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion.

30-06-2015

BMC cancer

PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort study.

30-06-2015

Frontiers in oncology

Spatial Separation of Plk1 Phosphorylation and Activity.

27-06-2015

Science (New York, N.Y.)

GENE REGULATION. A HUSH for transgene expression.

26-06-2015

Immunotherapy

Targeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potential.

23-06-2015

Nature

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis.

18-06-2015

Cell

Wnt Down, Tumors Wind Up?

18-06-2015

American journal of nuclear medicine and molecular imaging

The next evolution in radioguided surgery: breast cancer related sentinel node localization using a freehandSPECT-mobile gamma camera combination.

13-06-2015

Science (New York, N.Y.)

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling.

12-06-2015

Cell host & microbe

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma.

10-06-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Challenges in the Use of DNA Repair Deficiency As a Biomarker in Breast Cancer.

10-06-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Effect of Low-Intensity Physical Activity and Moderate- to High-Intensity Physical Exercise During Adjuvant Chemotherapy on Physical Fitness, Fatigue, and Chemotherapy Completion Rates: Results of the PACES Randomized Clinical Trial.

10-06-2015

Journal of pharmaceutical and biomedical analysis

Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil.

10-06-2015

Stem cell reports

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis.

09-06-2015

Cell cycle (Georgetown, Tex.)

Two-way communication between the metabolic and cell cycle machineries: the molecular basis.

04-06-2015

Diabetologia

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms. Reply to Pouwer F [letter].

01-06-2015

Molecular oncology

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

01-06-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Re-distribution of brachytherapy dose using a differential dose prescription adapted to risk of local failure in low-risk prostate cancer patients.

01-06-2015

Brain imaging and behavior

Neurotoxicity in breast cancer survivors ≥10 years post-treatment is dependent on treatment type.

01-06-2015

JAMA oncology

Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil.

01-06-2015

Veterinary and comparative oncology

Inductively coupled plasma mass-spectrometric determination of platinum in excretion products of client-owned pet dogs.

01-06-2015

Anticancer research

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

01-06-2015

JAMA internal medicine

Cardiovascular disease after Hodgkin lymphoma treatment: 40-year disease risk.

01-06-2015

Seminars in oncology

Toxicity patterns with immunomodulating antibodies and their combinations.

01-06-2015

The Lancet. Oncology

Controversies in defining cancer survivorship.

01-06-2015

Journal of medical genetics

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.

01-06-2015

Brain : a journal of neurology

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis.

01-06-2015

Acta oncologica (Stockholm, Sweden)

Establishing implantation uncertainties for focal brachytherapy with I-125 seeds for the treatment of localized prostate cancer.

01-06-2015

Nature

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

28-05-2015

Nature

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

28-05-2015

Trials

Impact of a web-based treatment decision aid for early-stage prostate cancer on shared decision-making and health outcomes: study protocol for a randomized controlled trial.

27-05-2015

mBio

Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.

26-05-2015

Proceedings of the National Academy of Sciences of the United States of America

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.

26-05-2015

Nature communications

Dissecting the role of aberrant DNA methylation in human leukaemia.

22-05-2015

Cell

In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior.

21-05-2015

Human molecular genetics

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

15-05-2015

Molecular biology of the cell

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

15-05-2015

Sensors (Basel, Switzerland)

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

12-05-2015

Scientific reports

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

12-05-2015

The EMBO journal

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.

12-05-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Molecular profiling is rather likely to be cost effective.

10-05-2015

Lancet (London, England)

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.

09-05-2015

Journal of applied clinical medical physics

Portal dosimetry in wedged beams.

08-05-2015

Journal of medical Internet research

Response rates for patient-reported outcomes using web-based versus paper questionnaires: comparison of two invitational methods in older colorectal cancer patients.

07-05-2015

Cell

Prospective derivation of a living organoid biobank of colorectal cancer patients.

07-05-2015

BMC cancer

Treatment strategies in colorectal cancer patients with initially unresectable liver-only metastases, a study protocol of the randomised phase 3 CAIRO5 study of the Dutch Colorectal Cancer Group (DCCG).

06-05-2015

Journal of the National Cancer Institute

Prediction of breast cancer risk based on profiling with common genetic variants.

01-05-2015

The proportion of postmenopausal breast cancer cases in the Netherlands attributable to lifestyle-related risk factors.

A phase IIb multicentre study comparing the efficacy of trabectedin to doxorubicin in patients with advanced or metastatic untreated soft tissue sarcoma: the TRUSTS trial.

Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma.

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion.

PIpelle Prospective ENDOmetrial carcinoma (PIPENDO) study, pre-operative recognition of high risk endometrial carcinoma: a multicentre prospective cohort study.

Spatial Separation of Plk1 Phosphorylation and Activity.

GENE REGULATION. A HUSH for transgene expression.

Targeting the T-cell co-stimulatory CD27/CD70 pathway in cancer immunotherapy: rationale and potential.

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis.

Wnt Down, Tumors Wind Up?

The next evolution in radioguided surgery: breast cancer related sentinel node localization using a freehandSPECT-mobile gamma camera combination.

CELL DIVISION CYCLE. Competition between MPS1 and microtubules at kinetochores regulates spindle checkpoint signaling.

Salmonella Manipulation of Host Signaling Pathways Provokes Cellular Transformation Associated with Gallbladder Carcinoma.

Challenges in the Use of DNA Repair Deficiency As a Biomarker in Breast Cancer.

Effect of Low-Intensity Physical Activity and Moderate- to High-Intensity Physical Exercise During Adjuvant Chemotherapy on Physical Fitness, Fatigue, and Chemotherapy Completion Rates: Results of the PACES Randomized Clinical Trial.

Development of an LC-MS/MS assay for the quantitative determination of the intracellular 5-fluorouracil nucleotides responsible for the anticancer effect of 5-fluorouracil.

Identification of the Common Origins of Osteoclasts, Macrophages, and Dendritic Cells in Human Hematopoiesis.

Two-way communication between the metabolic and cell cycle machineries: the molecular basis.

Impact of cancer on use of glucose-lowering drug treatment in individuals with diabetes: potential mechanisms. Reply to Pouwer F [letter].

Decreased expression of ABAT and STC2 hallmarks ER-positive inflammatory breast cancer and endocrine therapy resistance in advanced disease.

Re-distribution of brachytherapy dose using a differential dose prescription adapted to risk of local failure in low-risk prostate cancer patients.

Neurotoxicity in breast cancer survivors ≥10 years post-treatment is dependent on treatment type.

Increased Plasma Levels of Chemoresistance-Inducing Fatty Acid 16:4(n-3) After Consumption of Fish and Fish Oil.

Inductively coupled plasma mass-spectrometric determination of platinum in excretion products of client-owned pet dogs.

Effective Therapeutic Intervention and Comprehensive Genetic Analysis of mTOR Signaling in PEComa: A Case Report.

Cardiovascular disease after Hodgkin lymphoma treatment: 40-year disease risk.

Toxicity patterns with immunomodulating antibodies and their combinations.

Controversies in defining cancer survivorship.

Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers.

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis.

Establishing implantation uncertainties for focal brachytherapy with I-125 seeds for the treatment of localized prostate cancer.

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5' end resection.

Impact of a web-based treatment decision aid for early-stage prostate cancer on shared decision-making and health outcomes: study protocol for a randomized controlled trial.

Niemann-pick C1 is essential for ebolavirus replication and pathogenesis in vivo.

N-lactoyl-amino acids are ubiquitous metabolites that originate from CNDP2-mediated reverse proteolysis of lactate and amino acids.

Dissecting the role of aberrant DNA methylation in human leukaemia.

In Vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior.

Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2.

Integrin α3β1 regulates kidney collecting duct development via TRAF6-dependent K63-linked polyubiquitination of Akt.

MMP-2/9-Specific Activatable Lifetime Imaging Agent.

Dot1 histone methyltransferases share a distributive mechanism but have highly diverged catalytic properties.

Thymus-derived regulatory T cells restrain pro-inflammatory Th1 responses by downregulating CD70 on dendritic cells.

Molecular profiling is rather likely to be cost effective.

Maintenance treatment with capecitabine and bevacizumab in metastatic colorectal cancer (CAIRO3): a phase 3 randomised controlled trial of the Dutch Colorectal Cancer Group.

Portal dosimetry in wedged beams.

Response rates for patient-reported outcomes using web-based versus paper questionnaires: comparison of two invitational methods in older colorectal cancer patients.

Prospective derivation of a living organoid biobank of colorectal cancer patients.

Treatment strategies in colorectal cancer patients with initially unresectable liver-only metastases, a study protocol of the randomised phase 3 CAIRO5 study of the Dutch Colorectal Cancer Group (DCCG).

Prediction of breast cancer risk based on profiling with common genetic variants.

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