Publications

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Tumour delineation in oesophageal cancer - A prospective study of delineation in PET and CT with and without endoscopically placed clip markers.

European journal of cancer (Oxford, England : 1990)

Feasibility of a prospective, randomised, open-label, international multicentre, phase III, non-inferiority trial to assess the safety of active surveillance for low risk ductal carcinoma in situ - The LORD study.

Breast cancer research and treatment

Fat/water ratios measured with diffuse reflectance spectroscopy to detect breast tumor boundaries.

Lancet (London, England)

Dabrafenib and trametinib versus dabrafenib and placebo for Val600 BRAF-mutant melanoma: a multicentre, double-blind, phase 3 randomised controlled trial.

Clinical breast cancer

Tailored Tamoxifen Treatment for Breast Cancer Patients: A Perspective.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Radiation-induced dose-dependent changes of the spleen following postoperative chemoradiotherapy for gastric cancer.

Dysphagia

Effects of Strengthening Exercises on Swallowing Musculature and Function in Senior Healthy Subjects: a Prospective Effectiveness and Feasibility Study.

Pain

Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2⁺ breast cancer.

British journal of clinical pharmacology

Pharmacodynamics and pharmacokinetics of oral topotecan in patients with advanced solid tumours and impaired renal function.

Genes & development

Paracrine signaling between tumor subclones of mouse SCLC: a critical role of ETS transcription factor Pea3 in facilitating metastasis.

Breast cancer research and treatment

The prognostic value of the neoadjuvant response index in triple-negative breast cancer: validation and comparison with pathological complete response as outcome measure.

European urology

Reply to Eliezer M. Van Allen, Levi A. Garraway and Jonathan E. Rosenberg's Letter to the Editor re: Floris H. Groenendijk, Jeroen de Jong, Elisabeth E. Fransen van de Putte, et al. ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy. Eur Urol. In press. http://dx.doi.org/10.1016/j.eururo.2015.01.014.

The Lancet. Oncology

Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial.

Nature reviews. Cancer

Evolving synergistic combinations of targeted immunotherapies to combat cancer.

Breast (Edinburgh, Scotland)

Early stage cost-effectiveness analysis of a BRCA1-like test to detect triple negative breast cancers responsive to high dose alkylating chemotherapy.

The international journal of biochemistry & cell biology

Exposure to arginine analog canavanine induces aberrant mitochondrial translation products, mitoribosome stalling, and instability of the mitochondrial proteome.

Clinical pharmacokinetics

Effects of Pharmacogenetics on the Pharmacokinetics and Pharmacodynamics of Tamoxifen.

Biochimica et biophysica acta

C8-glycosphingolipids preferentially insert into tumor cell membranes and promote chemotherapeutic drug uptake.

European urology

Re: Alessandro Volpe, Kamran Ahmed, Prokar Dasgupta, et al. Pilot Validation Study of the European Association of Urology Robotic Training Curriculum. Eur Urol 2015;68:292-9.

Molecular oncology

Robust BRCA1-like classification of copy number profiles of samples repeated across different datasets and platforms.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Plasma membrane targeting by short chain sphingolipids inserted in liposomes improves anti-tumor activity of mitoxantrone in an orthotopic breast carcinoma xenograft model.

Radiation oncology (London, England)

Targeting anti-apoptotic Bcl-2 by AT-101 to increase radiation efficacy: data from in vitro and clinical pharmacokinetic studies in head and neck cancer.

30-07-2015

Health and quality of life outcomes

Validation of the French translation-adaptation of the impact of cancer questionnaire version 2 (IOCv2) in a breast cancer survivor population.

29-07-2015

British journal of cancer

Long-term safety and anti-tumour activity of olaparib monotherapy after combination with carboplatin and paclitaxel in patients with advanced breast, ovarian or fallopian tube cancer.

28-07-2015

British journal of cancer

Are metformin, statin and aspirin use still associated with overall mortality among colorectal cancer patients with diabetes if adjusted for one another?

28-07-2015

Science translational medicine

Optimizing sharing of hospital biobank samples.

22-07-2015

International journal of clinical and experimental pathology

Down-regulation of OATP1B proteins correlates with hyperbilirubinemia in advanced cholestasis.

21-07-2015

Ecancermedicalscience

Staff perceptions of change resulting from participation in a European cancer accreditation programme: a snapshot from eight cancer centres.

17-07-2015

PloS one

Co-Orientation: Quantifying Simultaneous Co-Localization and Orientational Alignment of Filaments in Light Microscopy.

15-07-2015

Genes & development

Origins, genetic landscape, and emerging therapies of small cell lung cancer.

15-07-2015

Cancer cell

Mismatch Repair-Deficient Cancers Are Targets for Anti-PD-1 Therapy.

13-07-2015

eLife

MutS/MutL crystal structure reveals that the MutS sliding clamp loads MutL onto DNA.

11-07-2015

PloS one

Studying Hospitalizations and Mortality in the Netherlands: Feasible and Valid Using Two-Step Medical Record Linkage with Nationwide Registers.

07-07-2015

PloS one

Oncogenic Role of miR-15a-3p in 13q Amplicon-Driven Colorectal Adenoma-to-Carcinoma Progression.

07-07-2015

Proceedings of the National Academy of Sciences of the United States of America

Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.

07-07-2015

BMC medicine

Annexin A1 expression in a pooled breast cancer series: association with tumor subtypes and prognosis.

The New England journal of medicine

Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma.

Journal of proteome research

Signal Transduction Reaction Monitoring Deciphers Site-Specific PI3K-mTOR/MAPK Pathway Dynamics in Oncogene-Induced Senescence.

American journal of human genetics

Polymorphisms in a Putative Enhancer at the 10q21.2 Breast Cancer Risk Locus Regulate NRBF2 Expression.

Nature

The core spliceosome as target and effector of non-canonical ATM signalling.

Trends in microbiology

Emerging intracellular receptors for hemorrhagic fever viruses.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Variation in fatigue among 6011 (long-term) cancer survivors and a normative population: a study from the population-based PROFILES registry.

Molecular biology of the cell

The rod domain is not essential for the function of plectin in maintaining tissue integrity.

Nature chemical biology

Chemical profiling of the genome with anti-cancer drugs defines target specificities.

CPT: pharmacometrics & systems pharmacology

Integrated Simulation Framework for Toxicity, Dose Intensity, Disease Progression, and Cost Effectiveness for Castration-Resistant Prostate Cancer Treatment With Eribulin.

Cell research

A price to pay for tumor regression.

Pharmaceutical research

Brain and Testis Accumulation of Regorafenib is Restricted by Breast Cancer Resistance Protein (BCRP/ABCG2) and P-glycoprotein (P-GP/ABCB1).