Publications

Cancer chemotherapy and pharmacology

Phase 1a/1b and pharmacogenetic study of docetaxel, oxaliplatin and capecitabine in patients with advanced cancer of the stomach or the gastroesophageal junction.

01-12-2015

Genes, chromosomes & cancer

Copy number profiling by array comparative genomic hybridization identifies frequently occurring BRCA2-like male breast cancer.

01-12-2015

Investigational new drugs

Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer.

01-12-2015

Therapeutic drug monitoring

Dried Blood Spot Self-Sampling at Home for the Individualization of Tamoxifen Treatment: A Feasibility Study.

01-12-2015

Psycho-oncology

Late effects of adjuvant chemotherapy for breast cancer on fine motor function.

01-12-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose-surface maps identifying local dose-effects for acute gastrointestinal toxicity after radiotherapy for prostate cancer.

01-12-2015

Pharmacological research

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2).

01-12-2015

The Lancet. Oncology

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.

01-12-2015

Molecular oncology

Tumor-infiltrating lymphocytes for the treatment of metastatic cancer.

01-12-2015

Current colorectal cancer reports

Treatment Individualization in Colorectal Cancer.

01-12-2015

Journal of medical Internet research

Empowerment of Cancer Survivors Through Information Technology: An Integrative Review.

27-11-2015

Science (New York, N.Y.)

Gene essentiality and synthetic lethality in haploid human cells.

27-11-2015

JMIR cancer

Effect of Web-Based Versus Paper-Based Questionnaires and Follow-Up Strategies on Participation Rates of Dutch Childhood Cancer Survivors: A Randomized Controlled Trial.

24-11-2015

BMC genomics

Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2.

21-11-2015

Nature

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

19-11-2015

Molecular cell

CTCF Binding Polarity Determines Chromatin Looping.

19-11-2015

eLife

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

14-11-2015

BMC cancer

Return-to-work intervention for cancer survivors: budget impact and allocation of costs and returns in the Netherlands and six major EU-countries.

12-11-2015

Oncotarget

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.

10-11-2015

Molecular cell

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.

05-11-2015

Nature protocols

Using the GEMM-ESC strategy to study gene function in mouse models.

01-11-2015

The Journal of allergy and clinical immunology

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency.

01-11-2015

European journal of cancer (Oxford, England : 1990)

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.

01-11-2015

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.

01-11-2015

Nature medicine

The consensus molecular subtypes of colorectal cancer.

01-11-2015

Human brain mapping

Lower cognitive performance and white matter changes in testicular cancer survivors 10 years after chemotherapy.

01-11-2015

Carcinogenesis

Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.

01-11-2015

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

The course of fatigue and its correlates in colorectal cancer survivors: a prospective cohort study of the PROFILES registry.

01-11-2015

Breast cancer research and treatment

Molecular subtyping improves diagnostic stratification of patients with primary breast cancer into prognostically defined risk groups.

01-11-2015

Acta oncologica (Stockholm, Sweden)

Recent trends and predictors of multimodality treatment for oesophageal, oesophagogastric junction, and gastric cancer: A Dutch cohort-study.

01-11-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Impact of tumour invasion on seminal vesicles mobility in radiotherapy of prostate cancer.

01-11-2015

Journal of the National Cancer Institute

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.

01-11-2015

Journal of immunology (Baltimore, Md. : 1950)

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules.

01-11-2015

Journal of immunology (Baltimore, Md. : 1950)

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage.

01-11-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial.

01-11-2015

Acta crystallographica. Section D, Biological crystallography

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

01-11-2015

European journal of cancer (Oxford, England : 1990)

The influence of prior novel androgen receptor targeted therapy on the efficacy of cabazitaxel in men with metastatic castration-resistant prostate cancer.

01-11-2015

EMBO molecular medicine

Androgen receptor profiling predicts prostate cancer outcome.

01-11-2015

Nature genetics

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

01-11-2015

Cell cycle (Georgetown, Tex.)

Tumor heterogeneity-induced signaling regulates SCLC metastasis.

29-10-2015

Proceedings of the National Academy of Sciences of the United States of America

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

27-10-2015

Frontiers in immunology

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.

27-10-2015

Journal of cell science

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

15-10-2015

International journal of cancer

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

15-10-2015

Journal of cell science

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

15-10-2015

Science (New York, N.Y.)

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

09-10-2015

Biomarkers in medicine

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

07-10-2015

Mobile genetic elements

Applications of DNA integrating elements: Facing the bias bully.

07-10-2015

Cell reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

06-10-2015

Oncogenesis

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

05-10-2015

Phase 1a/1b and pharmacogenetic study of docetaxel, oxaliplatin and capecitabine in patients with advanced cancer of the stomach or the gastroesophageal junction.

Copy number profiling by array comparative genomic hybridization identifies frequently occurring BRCA2-like male breast cancer.

Phase I and pharmacological trial of lapatinib in combination with gemcitabine in patients with advanced breast cancer.

Dried Blood Spot Self-Sampling at Home for the Individualization of Tamoxifen Treatment: A Feasibility Study.

Late effects of adjuvant chemotherapy for breast cancer on fine motor function.

Dose-surface maps identifying local dose-effects for acute gastrointestinal toxicity after radiotherapy for prostate cancer.

Brain accumulation of the EML4-ALK inhibitor ceritinib is restricted by P-glycoprotein (P-GP/ABCB1) and breast cancer resistance protein (BCRP/ABCG2).

Clinical relevance of DPYD variants c.1679T>G, c.1236G>A/HapB3, and c.1601G>A as predictors of severe fluoropyrimidine-associated toxicity: a systematic review and meta-analysis of individual patient data.

Tumor-infiltrating lymphocytes for the treatment of metastatic cancer.

Treatment Individualization in Colorectal Cancer.

Empowerment of Cancer Survivors Through Information Technology: An Integrative Review.

Gene essentiality and synthetic lethality in haploid human cells.

Effect of Web-Based Versus Paper-Based Questionnaires and Follow-Up Strategies on Participation Rates of Dutch Childhood Cancer Survivors: A Randomized Controlled Trial.

Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2.

Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage.

CTCF Binding Polarity Determines Chromatin Looping.

Bystander hyperactivation of preimmune CD8+ T cells in chronic HCV patients.

Return-to-work intervention for cancer survivors: budget impact and allocation of costs and returns in the Netherlands and six major EU-countries.

SNP-SNP interaction analysis of NF-κB signaling pathway on breast cancer survival.

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.

Using the GEMM-ESC strategy to study gene function in mouse models.

Impaired microbial killing by neutrophils from patients with protein kinase C delta deficiency.

Prognostic impact of immune response in resectable colorectal liver metastases treated by surgery alone or surgery with perioperative FOLFOX in the randomised EORTC study 40983.

Fine-scale mapping of the 4q24 locus identifies two independent loci associated with breast cancer risk.

The consensus molecular subtypes of colorectal cancer.

Lower cognitive performance and white matter changes in testicular cancer survivors 10 years after chemotherapy.

Autophagy-mediated degradation of nuclear envelope proteins during oncogene-induced senescence.

The course of fatigue and its correlates in colorectal cancer survivors: a prospective cohort study of the PROFILES registry.

Molecular subtyping improves diagnostic stratification of patients with primary breast cancer into prognostically defined risk groups.

Recent trends and predictors of multimodality treatment for oesophageal, oesophagogastric junction, and gastric cancer: A Dutch cohort-study.

Impact of tumour invasion on seminal vesicles mobility in radiotherapy of prostate cancer.

Height and Breast Cancer Risk: Evidence From Prospective Studies and Mendelian Randomization.

Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I Molecules.

Peptide Splicing in the Proteasome Creates a Novel Type of Antigen with an Isopeptide Linkage.

Impact of an Automatically Generated Cancer Survivorship Care Plan on Patient-Reported Outcomes in Routine Clinical Practice: Longitudinal Outcomes of a Pragmatic, Cluster Randomized Trial.

The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins.

The influence of prior novel androgen receptor targeted therapy on the efficacy of cabazitaxel in men with metastatic castration-resistant prostate cancer.

Androgen receptor profiling predicts prostate cancer outcome.

Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair.

Tumor heterogeneity-induced signaling regulates SCLC metastasis.

Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases.

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy.

Initiation of lamellipodia and ruffles involves cooperation between mDia1 and the Arp2/3 complex.

ABCB1 and ABCG2 restrict the brain penetration of a panel of novel EZH2-Inhibitors.

The molecular architecture of hemidesmosomes, as revealed with super-resolution microscopy.

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

Applications of DNA integrating elements: Facing the bias bully.

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

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