Publications

Current clinical pharmacology

Personalized medicine in oncology: a personal view with myths and facts.

01-08-2010

The Journal of clinical investigation

Organic anion transporting polypeptide 1a/1b-knockout mice provide insights into hepatic handling of bilirubin, bile acids, and drugs.

01-08-2010

Genes, chromosomes & cancer

Genomic profile of endometrial tumors depends on morphological subtype, not on tamoxifen exposure.

01-08-2010

International journal of radiation oncology, biology, physics

Radiation pneumonitis after hypofractionated radiotherapy: evaluation of the LQ(L) model and different dose parameters.

01-08-2010

European journal of nuclear medicine and molecular imaging

18F-FDG PET/CT for monitoring induction chemotherapy in patients with primary inoperable penile carcinoma: first clinical results.

01-08-2010

Cell

NF1 is a tumor suppressor in neuroblastoma that determines retinoic acid response and disease outcome.

23-07-2010

International journal of radiation oncology, biology, physics

Interobserver variation of clinical target volume delineation in gastric cancer.

15-07-2010

Mass spectrometry reviews

Mass spectrometry in the quantitative analysis of therapeutic intracellular nucleotide analogs.

14-07-2010

Journal of the American Chemical Society

Nonhydrolyzable ubiquitin-isopeptide isosteres as deubiquitinating enzyme probes.

07-07-2010

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Staging and management of axillary lymph nodes in patients with local recurrence in the breast or chest wall after a previous negative sentinel node procedure.

01-07-2010

Journal of tissue engineering and regenerative medicine

Dexamethasone treatment during the expansion phase maintains stemness of bone marrow mesenchymal stem cells.

01-07-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Rapid and robust transgenic high-grade glioma mouse models for therapy intervention studies.

01-07-2010

Oncology reports

Identification of serum proteins as prognostic and predictive markers of colorectal cancer using surface enhanced laser desorption ionization-time of flight mass spectrometry.

01-07-2010

British journal of pharmacology

Effects of cytochrome P450 3A (CYP3A) and the drug transporters P-glycoprotein (MDR1/ABCB1) and MRP2 (ABCC2) on the pharmacokinetics of lopinavir.

01-07-2010

Cancer causes & control : CCC

Cancer risk in DES daughters.

01-07-2010

Nucleic acids research

Structure of the FoxM1 DNA-recognition domain bound to a promoter sequence.

01-07-2010

Annals of oncology : official journal of the European Society for Medical Oncology

Two-protein signature of novel serological markers apolipoprotein-A2 and serum amyloid alpha predicts prognosis in patients with metastatic renal cell cancer and improves the currently used prognostic survival models.

01-07-2010

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Genetic testing in Li-Fraumeni syndrome: uptake and psychosocial consequences.

20-06-2010

Human antibodies

Pharmacokinetics of rituximab in patients with CD20 positive B-cell malignancies.

18-06-2010

Clinical cancer research : an official journal of the American Association for Cancer Research

Inhibition of the PI3K pathway: hope we can believe in?

15-06-2010

The Journal of experimental medicine

One naive T cell, multiple fates in CD8+ T cell differentiation.

07-06-2010

Journal of medical genetics

TP53 germline mutation testing in 180 families suspected of Li-Fraumeni syndrome: mutation detection rate and relative frequency of cancers in different familial phenotypes.

01-06-2010

The Journal of investigative dermatology

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

01-06-2010

Current opinion in cell biology

Genome-nuclear lamina interactions and gene regulation.

01-06-2010

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

HPV and high-risk gene expression profiles predict response to chemoradiotherapy in head and neck cancer, independent of clinical factors.

01-06-2010

Molecular cancer research : MCR

The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.

01-06-2010

Nature structural & molecular biology

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

01-06-2010

Medical physics

Catching errors with in vivo EPID dosimetry.

01-06-2010

Molecular cell

Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation.

28-05-2010

International journal of pharmaceutics

Lipopolysaccharide contamination in intradermal DNA vaccination: toxic impurity or adjuvant?

05-05-2010

British journal of clinical pharmacology

Population pharmacokinetics of intravenously and orally administered docetaxel with or without co-administration of ritonavir in patients with advanced cancer.

01-05-2010

Clinical genetics

Psychosocial impact of Von Hippel-Lindau disease: levels and sources of distress.

01-05-2010

European journal of cancer (Oxford, England : 1990)

Cost-effectiveness of the 70-gene signature versus St. Gallen guidelines and Adjuvant Online for early breast cancer.

01-05-2010

Cancer

Intra-arterial versus intravenous chemoradiation for advanced head and neck cancer: Results of a randomized phase 3 trial.

01-05-2010

Nature medicine

Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy.

01-05-2010

Annals of surgical oncology

Metastatic potential of T1 breast cancer can be predicted by the 70-gene MammaPrint signature.

01-05-2010

Proteins

Structure of human CLIC3 at 2 A resolution.

01-05-2010

The Journal of biological chemistry

Magnesium coordination controls the molecular switch function of DNA mismatch repair protein MutS.

23-04-2010

BMC genomics

Major role for mRNA stability in shaping the kinetics of gene induction.

21-04-2010

Proceedings of the National Academy of Sciences of the United States of America

Boronic acid-based inhibitor of autotaxin reveals rapid turnover of LPA in the circulation.

20-04-2010

Journal of cell science

The hinge region of the human estrogen receptor determines functional synergy between AF-1 and AF-2 in the quantitative response to estradiol and tamoxifen.

15-04-2010

Cell

Drugging drug resistance.

02-04-2010

Cell

It's diagnostics, stupid.

02-04-2010

Psycho-oncology

The impact of different definitions and reference groups on the prevalence of cognitive impairment: a study in postmenopausal breast cancer patients before the start of adjuvant systemic therapy.

01-04-2010

Annals of surgery

MRI-model to guide the surgical treatment in breast cancer patients after neoadjuvant chemotherapy.

01-04-2010

Molecular cancer research : MCR

Interleukin-1R-associated kinase 2 is a novel modulator of the transforming growth factor beta signaling cascade.

01-04-2010

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The role of FDG PET/CT in patients with locoregional breast cancer recurrence: a comparison to conventional imaging techniques.

01-04-2010

Annals of oncology : official journal of the European Society for Medical Oncology

The 70-gene prognosis signature predicts early metastasis in breast cancer patients between 55 and 70 years of age.

01-04-2010

Investigational new drugs

Disposition and toxicity of trabectedin (ET-743) in wild-type and mdr1 gene (P-gp) knock-out mice.

01-04-2010

Molecular pharmacology

Hepatic clearance of reactive glucuronide metabolites of diclofenac in the mouse is dependent on multiple ATP-binding cassette efflux transporters.

01-04-2010