Publications

Science (New York, N.Y.)

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

09-10-2015

Biomarkers in medicine

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

07-10-2015

Mobile genetic elements

Applications of DNA integrating elements: Facing the bias bully.

07-10-2015

Cell reports

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

06-10-2015

Oncogenesis

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

05-10-2015

Molecular pharmaceutics

P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice.

05-10-2015

Breast cancer research : BCR

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

03-10-2015

Journal of proteome research

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

02-10-2015

Nature reviews. Clinical oncology

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

01-10-2015

Journal of cancer research and clinical oncology

Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma.

01-10-2015

Annals of oncology : official journal of the European Society for Medical Oncology

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

01-10-2015

International journal of urology : official journal of the Japanese Urological Association

Advances in sentinel node dissection in prostate cancer from a technical perspective.

01-10-2015

Clinical cancer research : an official journal of the American Association for Cancer Research

Translating Pembrolizumab to Clinical Practice: Speak Immunology and Learn Fast!

01-10-2015

Molecular oncology

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

01-10-2015

Investigational new drugs

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

01-10-2015

Cancer research

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

01-10-2015

Scientific reports

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

01-10-2015

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Validation of high-performance liquid chromatography-tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4'‑des-methyl and cephalotaxine metabolites in human plasma and urine.

01-10-2015

Bioinformatics (Oxford, England)

xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.

01-10-2015

Gynecologic oncology

Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies.

01-10-2015

Cancer immunology, immunotherapy : CII

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma.

01-10-2015

European journal of nuclear medicine and molecular imaging

Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

01-10-2015

Molecular cell

High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.

01-10-2015

Immunology and cell biology

The importance of co-stimulation in the orchestration of T helper cell differentiation.

01-10-2015

European journal of nuclear medicine and molecular imaging

Fluorescent radiocolloids: are hybrid tracers the future for lymphatic mapping?

01-10-2015

European journal of nuclear medicine and molecular imaging

First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

01-10-2015

Cell reports

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.

29-09-2015

Oncogene

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

24-09-2015

Cell

Genome-wide maps of nuclear lamina interactions in single human cells.

24-09-2015

Oncotarget

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.

22-09-2015

Chinese journal of cancer

A multilevel pan-cancer map links gene mutations to cancer hallmarks.

14-09-2015

Implementation science : IS

Study protocol: an evaluation of the effectiveness, experiences and costs of a patient-directed strategy compared with a multi-faceted strategy to implement physical cancer rehabilitation programmes for cancer survivors in a European healthcare system; a controlled before and after study.

07-09-2015

BMC cancer

The value of completion axillary treatment in sentinel node positive breast cancer patients undergoing a mastectomy: a Dutch randomized controlled multicentre trial (BOOG 2013-07).

03-09-2015

Molecular therapy : the journal of the American Society of Gene Therapy

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

01-09-2015

Journal of cancer survivorship : research and practice

The impact of diabetes on neuropathic symptoms and receipt of chemotherapy among colorectal cancer patients: results from the PROFILES registry.

01-09-2015

JAMA oncology

Let Them Eat Fish--Reply.

01-09-2015

Journal of cancer survivorship : research and practice

Health-related quality of life is associated with physical activity levels among colorectal cancer survivors: a longitudinal, 3-year study of the PROFILES registry.

01-09-2015

Trends in molecular medicine

Stimulating translational research: several European life science institutions put their heads together.

01-09-2015

Lasers in surgery and medicine

Differentiation of healthy and malignant tissue in colon cancer patients using optical spectroscopy: A tool for image-guided surgery.

01-09-2015

Familial cancer

Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study.

01-09-2015

Journal of the National Cancer Institute

Response.

01-09-2015

Ophthalmology

Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma.

01-09-2015

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Cost-effectiveness of heat and moisture exchangers compared to usual care for pulmonary rehabilitation after total laryngectomy in Poland.

01-09-2015

EMBO molecular medicine

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

01-09-2015

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

01-09-2015

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

An interactive portal to empower cancer survivors: a qualitative study on user expectations.

01-09-2015

Pharmacoepidemiology and drug safety

Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review.

01-09-2015

British journal of cancer

Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.

01-09-2015

JAMA otolaryngology-- head & neck surgery

Prediction of Hearing Loss Due to Cisplatin Chemoradiotherapy.

01-09-2015

eLife

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

01-09-2015

Genomic correlates of response to CTLA-4 blockade in metastatic melanoma.

Prognostic significance of the EGFR pathway in nasopharyngeal carcinoma: a systematic review and meta-analysis.

Applications of DNA integrating elements: Facing the bias bully.

APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.

MiR expression profiles of paired primary colorectal cancer and metastases by next-generation sequencing.

P-glycoprotein, CYP3A, and Plasma Carboxylesterase Determine Brain Disposition and Oral Availability of the Novel Taxane Cabazitaxel (Jevtana) in Mice.

Next generation sequencing of triple negative breast cancer to find predictors for chemotherapy response.

PhosphoPath: Visualization of Phosphosite-centric Dynamics in Temporal Molecular Networks.

Cognitive effects of endocrine therapy for breast cancer: keep calm and carry on?

Epstein-Barr virus-targeted therapy in nasopharyngeal carcinoma.

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

Advances in sentinel node dissection in prostate cancer from a technical perspective.

Translating Pembrolizumab to Clinical Practice: Speak Immunology and Learn Fast!

BRCA1-like signature in triple negative breast cancer: Molecular and clinical characterization reveals subgroups with therapeutic potential.

P-glycoprotein and breast cancer resistance protein restrict the brain penetration of the CDK4/6 inhibitor palbociclib.

Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.

The lethal response to Cdk1 inhibition depends on sister chromatid alignment errors generated by KIF4 and isoform 1 of PRC1.

Validation of high-performance liquid chromatography-tandem mass spectrometry assays quantifying omacetaxine mepesuccinate and its 4'‑des-methyl and cephalotaxine metabolites in human plasma and urine.

xHeinz: an algorithm for mining cross-species network modules under a flexible conservation model.

Characterization of patient-derived tumor xenograft models of endometrial cancer for preclinical evaluation of targeted therapies.

Sunitinib pretreatment improves tumor-infiltrating lymphocyte expansion by reduction in intratumoral content of myeloid-derived suppressor cells in human renal cell carcinoma.

Erratum to: First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila.

The importance of co-stimulation in the orchestration of T helper cell differentiation.

Fluorescent radiocolloids: are hybrid tracers the future for lymphatic mapping?

First-in-human evaluation of a hybrid modality that allows combined radio- and (near-infrared) fluorescence tracing during surgery.

PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs.

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

Genome-wide maps of nuclear lamina interactions in single human cells.

MGL ligand expression is correlated to BRAF mutation and associated with poor survival of stage III colon cancer patients.

A multilevel pan-cancer map links gene mutations to cancer hallmarks.

Study protocol: an evaluation of the effectiveness, experiences and costs of a patient-directed strategy compared with a multi-faceted strategy to implement physical cancer rehabilitation programmes for cancer survivors in a European healthcare system; a controlled before and after study.

The value of completion axillary treatment in sentinel node positive breast cancer patients undergoing a mastectomy: a Dutch randomized controlled multicentre trial (BOOG 2013-07).

Case Report of a Fatal Serious Adverse Event Upon Administration of T Cells Transduced With a MART-1-specific T-cell Receptor.

The impact of diabetes on neuropathic symptoms and receipt of chemotherapy among colorectal cancer patients: results from the PROFILES registry.

Let Them Eat Fish--Reply.

Health-related quality of life is associated with physical activity levels among colorectal cancer survivors: a longitudinal, 3-year study of the PROFILES registry.

Stimulating translational research: several European life science institutions put their heads together.

Differentiation of healthy and malignant tissue in colon cancer patients using optical spectroscopy: A tool for image-guided surgery.

Timing of risk reducing mastectomy in breast cancer patients carrying a BRCA1/2 mutation: retrospective data from the Dutch HEBON study.

Response.

Serous Retinopathy Associated with Mitogen-Activated Protein Kinase Kinase Inhibition (Binimetinib) for Metastatic Cutaneous and Uveal Melanoma.

Cost-effectiveness of heat and moisture exchangers compared to usual care for pulmonary rehabilitation after total laryngectomy in Poland.

Intra- and inter-tumor heterogeneity in a vemurafenib-resistant melanoma patient and derived xenografts.

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

An interactive portal to empower cancer survivors: a qualitative study on user expectations.

Data management and data analysis techniques in pharmacoepidemiological studies using a pre-planned multi-database approach: a systematic literature review.

Phase I and pharmacological study of pazopanib in combination with oral topotecan in patients with advanced solid tumours.

Prediction of Hearing Loss Due to Cisplatin Chemoradiotherapy.

Compromising the 19S proteasome complex protects cells from reduced flux through the proteasome.

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