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Irradiation of localized squamous cell carcinoma of the nasal vestibule.

Ben G L Vanneste ,
Marta Lopez-Yurda ,
I Bing Tan ,
Alfons J M Balm ,
Gerben R Borst ,
Coen R Rasch

Abstract

METHODS

Eighty-one patients were treated with external beam radiotherapy (EBRT) and/or interstitial radiotherapy (IRT) for a primary, localized, Wang classified SCC of the nasal vestibule.

CONCLUSION

Local primary radiotherapy (either IRT for T1 or EBRT for T2/3) is an adequate treatment for SCC of the nasal vestibule with little late sequelae. © 2015 Wiley Periodicals, Inc. Head Neck 38: E1870-E1875, 2016.

RESULTS

Median follow-up was 38 months. T1 tumors were treated with IRT: we observed 1 local failure (at 13 months) among 48 patients (5-year local control rate of 97%). Most T2 tumors (20 of 26) were treated with EBRT. There were 8 local recurrences among 26 patients (5-year local control rate of 68%). For the T3 tumors (n = 7; all treated with EBRT), we observed local recurrence in 2 patients (5-year local control rate of 53%). The late-term side effects were relatively mild.

BACKGROUND

The purpose of this study was to evaluate the long-term results of primary radiotherapy treatment for squamous cell carcinoma (SCC) of the nasal vestibule.

More about this publication

Head & neck

Volume 38 Suppl 1
Pages E1870-5
Publication date 01-04-2016

Full text links

Publisher website (DOI) 10.1002/hed.24337
Europe PubMed Central 26706779
Pubmed 26706779

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