Publications

Investigational new drugs

Pharmacokinetics and excretion of (14)C-lenvatinib in patients with advanced solid tumors or lymphomas.

Annals of surgery

Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure.

DNA repair

DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity.

Melanoma research

Cross-cultural development of a quality-of-life measure for patients with melanoma: phase 3 testing of an EORTC Melanoma Module.

Annals of surgical oncology

Does adjuvant chemoradiotherapy improve the prognosis of gastric cancer after an r1 resection? Results from a dutch cohort study.

European urology

The molecular background of urothelial cancer: ready for action?

Investigational new drugs

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.

Carcinogenesis

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Clinical genitourinary cancer

Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer.

Nature genetics

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

World journal of surgery

Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy.

Head & neck

Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy: a systematic review of the literature.

Oncogene

Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL.

29-01-2015

Ecancermedicalscience

Report from the OECI Oncology Days 2014.

28-01-2015

Journal of translational medicine

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy.

27-01-2015

J Pathol.: The journal of pathology

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

23-01-2015

Science (New York, N.Y.)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

23-01-2015

Molecular cell

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

JMIR research protocols

Development of MijnAVL, an Interactive Portal to Empower Breast and Lung Cancer Survivors: An Iterative, Multi-Stakeholder Approach.

Oncogene

A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.

Molecular cell

Transcription initiation determines its end.

J Proteome Res.: Journal of proteome research

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer

20-01-2015

Cell reports

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

20-01-2015

Oncoscience

P-gp and taxanes.

17-01-2015

Experimental cell research

Quantitative imaging of focal adhesion dynamics and their regulation by HGF and Rap1 signaling.

15-01-2015

Cancer cell

Biomarkers in cancer immunotherapy.

12-01-2015

American journal of human genetics

Fine-scale mapping of the 5q11.2 breast cancer locus reveals at least three independent risk variants regulating MAP3K1.

08-01-2015

British journal of cancer

Increased stomach cancer risk following radiotherapy for testicular cancer.

06-01-2015

International immunology

Therapeutic use of anti-CTLA-4 antibodies.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

The value of optical coherence tomography in determining surgical margins in squamous cell carcinoma of the vulva: a single-center prospective study.

European journal of cancer (Oxford, England : 1990)

Increased breast cancer risk in in vitro fertilisation treated women with a multiple pregnancy: a new hypothesis based on historical in vitro fertilisation treatment data.

Annals of hematology

Impact of active surveillance, chlorambucil, and other therapy on health-related quality of life in patients with CLL/SLL in the Netherlands.

Human molecular genetics

Identification and characterization of novel associations in the CASP8/ALS2CR12 region on chromosome 2 with breast cancer risk.

International journal of radiation oncology, biology, physics

Valvular abnormalities detected by echocardiography in 5-year survivors of childhood cancer: a long-term follow-up study.

Journal of the International Neuropsychological Society : JINS

Very Late Treatment-Related Alterations in Brain Function of Breast Cancer Survivors.

International journal of cancer

Human OATP1B1, OATP1B3 and OATP1A2 can mediate the in vivo uptake and clearance of docetaxel.

Antimicrobial agents and chemotherapy

Systematic review of biomarkers to monitor therapeutic response in leishmaniasis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Lymphovascular space invasion and the treatment of stage I endometrioid endometrial cancer.

Journal of cell science

N-terminal acetylation and replicative age affect proteasome localization and cell fitness during aging.

Nature genetics

A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.

Nucleic acids research

Roles of PCNA ubiquitination and TLS polymerases κ and η in the bypass of methyl methanesulfonate-induced DNA damage.

European journal of cancer (Oxford, England : 1990)

Management of sporadic desmoid-type fibromatosis: a European consensus approach based on patients' and professionals' expertise - a sarcoma patients EuroNet and European Organisation for Research and Treatment of Cancer/Soft Tissue and Bone Sarcoma Group initiative.