Publications

Pharmacology research & perspectives

Incorporation of concentration data below the limit of quantification in population pharmacokinetic analyses.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Target delineation variability and corresponding margins of peripheral early stage NSCLC treated with stereotactic body radiotherapy.

European journal of clinical pharmacology

Baclofen overdose treated with continuous venovenous hemofiltration.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Overcoming the blood-brain tumor barrier for effective glioblastoma treatment.

Neuro-oncology practice

Predictors of subjective versus objective cognitive functioning in patients with stable grades II and III glioma.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The effect of age in breast conserving therapy: a retrospective analysis on pathology and clinical outcome data.

Genome biology

CopywriteR: DNA copy number detection from off-target sequence data.

27-02-2015

Radiation oncology (London, England)

A cell-based high-throughput screening assay for radiation susceptibility using automated cell counting.

27-02-2015

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prevalence of cerebral small-vessel disease in long-term breast cancer survivors exposed to both adjuvant radiotherapy and chemotherapy.

20-02-2015

Blood

Loss of PRDM11 promotes MYC-driven lymphomagenesis.

19-02-2015

Clinical cancer research : an official journal of the American Association for Cancer Research

Breast cancers with a BRCA1-like DNA copy number profile recur less often than expected after high-dose alkylating chemotherapy.

Journal of cell science

The same, only different - DNA damage checkpoints and their reversal throughout the cell cycle.

Cancer research

BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.

Practical radiation oncology

Probabilistic evaluation of target dose deterioration in dose painting by numbers for stage II/III lung cancer.

The Cochrane database of systematic reviews

Conservative interventions for preventing clinically detectable upper-limb lymphoedema in patients who are at risk of developing lymphoedema after breast cancer therapy.

13-02-2015

The EMBO journal

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.

03-02-2015

Proceedings of the National Academy of Sciences of the United States of America

The first step of peptide selection in antigen presentation by MHC class I molecules.

03-02-2015

Advances in cancer research

Apical ABC transporters and cancer chemotherapeutic drug disposition.

03-02-2015

International journal of pharmaceutics

Stability of oxaliplatin in chloride-containing carrier solutions used in hyperthermic intraperitoneal chemotherapy.

Investigational new drugs

Pharmacokinetics and excretion of (14)C-lenvatinib in patients with advanced solid tumors or lymphomas.

Annals of surgery

Marking axillary lymph nodes with radioactive iodine seeds for axillary staging after neoadjuvant systemic treatment in breast cancer patients: the MARI procedure.

DNA repair

DNA helicases FANCM and DDX11 are determinants of PARP inhibitor sensitivity.

Melanoma research

Cross-cultural development of a quality-of-life measure for patients with melanoma: phase 3 testing of an EORTC Melanoma Module.

Annals of surgical oncology

Does adjuvant chemoradiotherapy improve the prognosis of gastric cancer after an r1 resection? Results from a dutch cohort study.

European urology

The molecular background of urothelial cancer: ready for action?

Investigational new drugs

Phase I/II study with ruthenium compound NAMI-A and gemcitabine in patients with non-small cell lung cancer after first line therapy.

Carcinogenesis

Inherited variants in the inner centromere protein (INCENP) gene of the chromosomal passenger complex contribute to the susceptibility of ER-negative breast cancer.

Clinical genitourinary cancer

Neoadjuvant taxane-based combination chemotherapy in patients with advanced penile cancer.

Nature genetics

Identification of six new susceptibility loci for invasive epithelial ovarian cancer.

World journal of surgery

Implementation of a standardized HIPEC protocol improves outcome for peritoneal malignancy.

Head & neck

Sensorineural hearing loss in patients with head and neck cancer after chemoradiotherapy and radiotherapy: a systematic review of the literature.

Oncogene

Delaying mitotic exit downregulates FLIP expression and strongly sensitizes tumor cells to TRAIL.

29-01-2015

Ecancermedicalscience

Report from the OECI Oncology Days 2014.

28-01-2015

Journal of translational medicine

NHS-IL2 combined with radiotherapy: preclinical rationale and phase Ib trial results in metastatic non-small cell lung cancer following first-line chemotherapy.

27-01-2015

J Pathol.: The journal of pathology

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

23-01-2015

Science (New York, N.Y.)

T cell immunity. Functional heterogeneity of human memory CD4⁺ T cell clones primed by pathogens or vaccines.

23-01-2015

Molecular cell

Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.

JMIR research protocols

Development of MijnAVL, an Interactive Portal to Empower Breast and Lung Cancer Survivors: An Iterative, Multi-Stakeholder Approach.

Oncogene

A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.

Molecular cell

Transcription initiation determines its end.