Publications

Cancer research

Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer.

15-11-2013

Cancer research

Crizotinib inhibits metabolic inactivation of gemcitabine in c-Met-driven pancreatic carcinoma.

15-11-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Tumor exome analysis reveals neoantigen-specific T-cell reactivity in an ipilimumab-responsive melanoma.

10-11-2013

Journal of X-ray science and technology

Directional sinogram interpolation for sparse angular acquisition in cone-beam computed tomography.

07-11-2013

Nature medicine

High-throughput identification of antigen-specific TCRs by TCR gene capture.

01-11-2013

Breast cancer research and treatment

Genomic profiling of histological special types of breast cancer.

01-11-2013

The Journal of biological chemistry

The Geminin and Idas coiled coils preferentially form a heterodimer that inhibits Geminin function in DNA replication licensing.

01-11-2013

Acta oncologica (Stockholm, Sweden)

Ipilimumab in pretreated metastastic uveal melanoma patients. Results of the Dutch Working group on Immunotherapy of Oncology (WIN-O).

01-11-2013

Nucleic acids research

Identifying subgroup markers in heterogeneous populations.

01-11-2013

Psycho-oncology

Low socioeconomic status and mental health outcomes in colorectal cancer survivors: disadvantage? advantage?... or both?

01-11-2013

Journal of translational medicine

Assessing excellence in translational cancer research: a consensus based framework.

29-10-2013

Current biology : CB

WAPL-mediated removal of cohesin protects against segregation errors and aneuploidy.

21-10-2013

The EMBO journal

Lncing protein translation to metastasis.

16-10-2013

Clinical cancer research : an official journal of the American Association for Cancer Research

Identification of lethal microRNAs specific for head and neck cancer.

15-10-2013

European journal of pharmacology

Tamoxifen resistance: from bench to bedside.

05-10-2013

European journal of pharmacology

Taxanes: old drugs, new oral formulations.

05-10-2013

Cell research

eRNAs reach the heart of transcription.

01-10-2013

Breast (Edinburgh, Scotland)

Breast cancer in women at high risk: the role of rapid genetic testing for BRCA1 and -2 mutations and the consequences for treatment strategies.

01-10-2013

Breast (Edinburgh, Scotland)

FDG PET/CT during neoadjuvant chemotherapy may predict response in ER-positive/HER2-negative and triple negative, but not in HER2-positive breast cancer.

01-10-2013

Breast (Edinburgh, Scotland)

Scalp cooling to prevent alopecia after chemotherapy can be considered safe in patients with breast cancer.

01-10-2013

Diabetic medicine : a journal of the British Diabetic Association

Diminishing differences in treatment between patients with colorectal cancer with and without diabetes: a population-based study.

01-10-2013

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Microscopic disease extensions as a risk factor for loco-regional recurrence of NSCLC after SBRT.

01-10-2013

Cancer treatment reviews

Effect of inhibition of the FGFR-MAPK signaling pathway on the development of ocular toxicities.

01-10-2013

Thyroid : official journal of the American Thyroid Association

Fatigue among short- and long-term thyroid cancer survivors: results from the population-based PROFILES registry.

01-10-2013

Nature methods

hiFRET: some tailwind for FRET resolves weak protein interactions.

01-10-2013

European journal of oncology nursing : the official journal of European Oncology Nursing Society

Impact of scalp cooling on chemotherapy-induced alopecia, wig use and hair growth of patients with cancer.

01-10-2013

Cancer discovery

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

01-10-2013

Pharmacological research

P-glycoprotein (MDR1/ABCB1) and breast cancer resistance protein (BCRP/ABCG2) restrict brain accumulation of the JAK1/2 inhibitor, CYT387.

01-10-2013

Annals of oncology : official journal of the European Society for Medical Oncology

Efficacy and safety of ipilimumab in metastatic melanoma patients surviving more than 2 years following treatment in a phase III trial (MDX010-20).

01-10-2013

Molecular oncology

A gene signature for late distant metastasis in breast cancer identifies a potential mechanism of late recurrences.

01-10-2013

Investigational new drugs

Effect of the drug transporters ABCG2, Abcg2, ABCB1 and ABCC2 on the disposition, brain accumulation and myelotoxicity of the aurora kinase B inhibitor barasertib and its more active form barasertib-hydroxy-QPA.

01-10-2013

Critical reviews in oncology/hematology

Late effects of adjuvant chemotherapy for adult onset non-CNS cancer; cognitive impairment, brain structure and risk of dementia.

01-10-2013

European journal of immunology

Rev1 is essential in generating G to C transversions downstream of the Ung2 pathway but not the Msh2+Ung2 hybrid pathway.

01-10-2013

International journal of radiation oncology, biology, physics

PET motion compensation for radiation therapy using a CT-based mid-position motion model: methodology and clinical evaluation.

01-10-2013

Breast cancer research and treatment

Radiation- and anthracycline-induced cardiac toxicity and the influence of ErbB2 blocking agents.

01-10-2013

Methods in molecular biology (Clifton, N.J.)

Detecting cAMP with an EPAC-based FRET sensor in single living cells.

21-09-2013

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Stomach cancer risk after treatment for hodgkin lymphoma.

20-09-2013

Oncogene

Genetic instability: tipping the balance.

19-09-2013

Journal of immunology (Baltimore, Md. : 1950)

Blockade of TGF-β signaling greatly enhances the efficacy of TCR gene therapy of cancer.

15-09-2013

Rapid communications in mass spectrometry : RCM

Quantification of docetaxel and its metabolites in human plasma by liquid chromatography/tandem mass spectrometry.

15-09-2013

Cell cycle (Georgetown, Tex.)

TGF-β: an emerging player in drug resistance.

15-09-2013

Journal of immunology (Baltimore, Md. : 1950)

CD8+ T cells produce the chemokine CXCL10 in response to CD27/CD70 costimulation to promote generation of the CD8+ effector T cell pool.

15-09-2013

International journal of pharmaceutics

Long term stability of lyophilized plasmid DNA pDERMATT.

10-09-2013

Stem Cells (Dayton, Ohio)

Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal

01-09-2013

International journal of cancer

Dual mTORC1 and mTORC2 inhibitor Palomid 529 penetrates the blood-brain barrier without restriction by ABCB1 and ABCG2.

01-09-2013

Nucleic acids research

Using stable MutS dimers and tetramers to quantitatively analyze DNA mismatch recognition and sliding clamp formation.

01-09-2013

The Journal of investigative dermatology

Kindlin-1 mutant zebrafish as an in vivo model system to study adhesion mechanisms in the epidermis.

01-09-2013

Stem cells (Dayton, Ohio)

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

01-09-2013

Nucleic acids research

A versatile microsatellite instability reporter system in human cells.

01-09-2013

Gynecologic oncology

Phase I dose-escalation study and population pharmacokinetic analysis of fixed dose rate gemcitabine plus carboplatin as second-line therapy in patients with ovarian cancer.

01-09-2013