Publications

Cell host & microbe

Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.

11-10-2017

Nature biotechnology

Antigen receptor repertoire profiling from RNA-seq data.

11-10-2017

Science (New York, N.Y.)

Neutrophils take a round-trip.

06-10-2017

The New England journal of medicine

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

05-10-2017

Molecular pharmaceutics

Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2).

02-10-2017

Journal of the National Cancer Institute

Post-traumatic Stress as the Primary Cause for Cognitive Decline-Not the Whole Story, and Perhaps No Story at All.

01-10-2017

Current opinion in chemical biology

A three-step framework for programming pattern formation.

01-10-2017

Human mutation

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

01-10-2017

Clinical and translational radiation oncology

A predictive model for residual disease after (chemo) radiotherapy in oropharyngeal carcinoma: Combined radiological and clinical evaluation of tumor response.

01-10-2017

Genome research

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

01-10-2017

European journal of cancer (Oxford, England : 1990)

Hormone replacement therapy after risk-reducing salpingo-oophorectomy minimises endocrine and sexual problems: A prospective study.

01-10-2017

Lung cancer (Amsterdam, Netherlands)

Outcome of radical local treatment of non-small cell lung cancer patients with synchronous oligometastases.

01-10-2017

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Heart dose associated with overall survival in locally advanced NSCLC patients treated with hypofractionated chemoradiotherapy.

01-10-2017

European journal of immunology

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

01-10-2017

Annals of oncology : official journal of the European Society for Medical Oncology

Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study.

01-10-2017

The journal of sexual medicine

Factors Associated With Specific Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Sexual Dysfunctions in Breast Cancer Survivors: A Study of Patients and Their Partners.

01-10-2017

Molecular & cellular proteomics : MCP

Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.

01-10-2017

EMBO molecular medicine

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

01-10-2017

Diseases of the colon and rectum

Quality of Life in Rectal Cancer Patients After Chemoradiation: Watch-and-Wait Policy Versus Standard Resection - A Matched-Controlled Study.

01-10-2017

Annals of surgical oncology

Adherence to Guidelines for Adult (Non-GIST) Soft Tissue Sarcoma in the Netherlands: A Plea for Dedicated Sarcoma Centers.

01-10-2017

Investigational new drugs

Pharmacokinetics and excretion of ¹⁴C-Plitidepsin in patients with advanced cancer.

01-10-2017

Magnetic resonance imaging

Towards intrinsic R2* imaging in the prostate at 3 and 7tesla.

01-10-2017

Journal of biomedical optics

Diffuse reflectance spectroscopy as a tool for real-time tissue assessment during colorectal cancer surgery.

01-10-2017

European urology

Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy.

01-10-2017

The British journal of dermatology

Histological diagnosis of basal cell carcinoma is not associated with life expectancy in elderly Dutch people: a population-based cohort study.

01-10-2017

The pharmacogenomics journal

Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies.

01-10-2017

The oncologist

Fixed Dosing of Monoclonal Antibodies in Oncology.

01-10-2017

Annals of oncology : official journal of the European Society for Medical Oncology

An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG).

01-10-2017

European journal of radiology

Value of DCE-MRI for staging and response evaluation in rectal cancer: A systematic review.

01-10-2017

Disability and rehabilitation

Cancer survivors' perspectives and experiences regarding behavioral determinants of return to work and continuation of work.

01-10-2017

European radiology

Diffusion-weighted MRI to assess response to chemoradiotherapy in rectal cancer: main interpretation pitfalls and their use for teaching.

01-10-2017

Contemporary clinical trials

Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: Alternative versus standard stimulation protocols; the study protocol of the STIM-trial.

01-10-2017

Head & neck

Efficacy of a novel swallowing exercise program for chronic dysphagia in long-term head and neck cancer survivors.

01-10-2017

Ecancermedicalscience

Responsible pricing in value-based assessment of cancer drugs: real-world data are an inevitable addition to select meaningful new cancer treatments.

29-09-2017

JMIR cancer

The Impact of Participation in Online Cancer Communities on Patient Reported Outcomes: Systematic Review.

28-09-2017

NPJ breast cancer

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

28-09-2017

Oncotarget

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

26-09-2017

Oncotarget

TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines.

22-09-2017

Oncotarget

Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.

22-09-2017

Cell chemical biology

Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery.

21-09-2017

Physics in medicine and biology

Beyond the margin recipe: the probability of correct target dosage and tumor control in the presence of a dose limiting structure.

20-09-2017

Oncoimmunology

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.

19-09-2017

Cell reports

Cohesin Can Remain Associated with Chromosomes during DNA Replication.

19-09-2017

BMC cancer

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter study.

15-09-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

15-09-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity.

15-09-2017

Oncotarget

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer.

08-09-2017

American journal of human genetics

Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping.

07-09-2017

Cell

Converting Cold into Hot Tumors by Combining Immunotherapies.

07-09-2017

Nature

Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.

07-09-2017

Diverse Viruses Require the Calcium Transporter SPCA1 for Maturation and Spread.

Antigen receptor repertoire profiling from RNA-seq data.

Neutrophils take a round-trip.

Overall Survival with Combined Nivolumab and Ipilimumab in Advanced Melanoma.

Brain Accumulation of Ponatinib and Its Active Metabolite, N-Desmethyl Ponatinib, Is Limited by P-Glycoprotein (P-GP/ABCB1) and Breast Cancer Resistance Protein (BCRP/ABCG2).

Post-traumatic Stress as the Primary Cause for Cognitive Decline-Not the Whole Story, and Perhaps No Story at All.

A three-step framework for programming pattern formation.

Hermansky-Pudlak syndrome type 2: Aberrant pre-mRNA splicing and mislocalization of granule proteins in neutrophils.

A predictive model for residual disease after (chemo) radiotherapy in oropharyngeal carcinoma: Combined radiological and clinical evaluation of tumor response.

Massive reshaping of genome-nuclear lamina interactions during oncogene-induced senescence.

Hormone replacement therapy after risk-reducing salpingo-oophorectomy minimises endocrine and sexual problems: A prospective study.

Outcome of radical local treatment of non-small cell lung cancer patients with synchronous oligometastases.

Heart dose associated with overall survival in locally advanced NSCLC patients treated with hypofractionated chemoradiotherapy.

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Vemurafenib in patients with BRAFV600 mutation-positive metastatic melanoma: final overall survival results of the randomized BRIM-3 study.

Factors Associated With Specific Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Sexual Dysfunctions in Breast Cancer Survivors: A Study of Patients and Their Partners.

Identification of Differentially Expressed Splice Variants by the Proteogenomic Pipeline Splicify.

BRCA1 and BRCA2 tumor suppressors protect against endogenous acetaldehyde toxicity.

Quality of Life in Rectal Cancer Patients After Chemoradiation: Watch-and-Wait Policy Versus Standard Resection - A Matched-Controlled Study.

Adherence to Guidelines for Adult (Non-GIST) Soft Tissue Sarcoma in the Netherlands: A Plea for Dedicated Sarcoma Centers.

Pharmacokinetics and excretion of 14C-Plitidepsin in patients with advanced cancer.

Towards intrinsic R2* imaging in the prostate at 3 and 7tesla.

Diffuse reflectance spectroscopy as a tool for real-time tissue assessment during colorectal cancer surgery.

Impact of Molecular Subtypes in Muscle-invasive Bladder Cancer on Predicting Response and Survival after Neoadjuvant Chemotherapy.

Histological diagnosis of basal cell carcinoma is not associated with life expectancy in elderly Dutch people: a population-based cohort study.

Pharmacogenetic variants associated with outcome in patients with advanced gastric cancer treated with fluoropyrimidine and platinum-based triplet combinations: a pooled analysis of three prospective studies.

Fixed Dosing of Monoclonal Antibodies in Oncology.

An update on the management of sporadic desmoid-type fibromatosis: a European Consensus Initiative between Sarcoma PAtients EuroNet (SPAEN) and European Organization for Research and Treatment of Cancer (EORTC)/Soft Tissue and Bone Sarcoma Group (STBSG).

Value of DCE-MRI for staging and response evaluation in rectal cancer: A systematic review.

Cancer survivors' perspectives and experiences regarding behavioral determinants of return to work and continuation of work.

Diffusion-weighted MRI to assess response to chemoradiotherapy in rectal cancer: main interpretation pitfalls and their use for teaching.

Stimulation of the ovaries in women with breast cancer undergoing fertility preservation: Alternative versus standard stimulation protocols; the study protocol of the STIM-trial.

Efficacy of a novel swallowing exercise program for chronic dysphagia in long-term head and neck cancer survivors.

Responsible pricing in value-based assessment of cancer drugs: real-world data are an inevitable addition to select meaningful new cancer treatments.

The Impact of Participation in Online Cancer Communities on Patient Reported Outcomes: Systematic Review.

DNA repair deficiency biomarkers and the 70-gene ultra-high risk signature as predictors of veliparib/carboplatin response in the I-SPY 2 breast cancer trial.

Identification of a novel ATM inhibitor with cancer cell specific radiosensitization activity.

TUBB3 overexpression has a negligible effect on the sensitivity to taxol in cultured cell lines.

Intraductal cisplatin treatment in a BRCA-associated breast cancer mouse model attenuates tumor development but leads to systemic tumors in aged female mice.

Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery.

Beyond the margin recipe: the probability of correct target dosage and tumor control in the presence of a dose limiting structure.

Mammary tumor-derived CCL2 enhances pro-metastatic systemic inflammation through upregulation of IL1β in tumor-associated macrophages.

Cohesin Can Remain Associated with Chromosomes during DNA Replication.

Vemurafenib plus cobimetinib in unresectable stage IIIc or stage IV melanoma: response monitoring and resistance prediction with positron emission tomography and tumor characteristics (REPOSIT): study protocol of a phase II, open-label, multicenter study.

Modeling the Cellular Response of Lung Cancer to Radiation Therapy for a Broad Range of Fractionation Schedules.

Phase Ib Study of Lumretuzumab Plus Cetuximab or Erlotinib in Solid Tumor Patients and Evaluation of HER3 and Heregulin as Potential Biomarkers of Clinical Activity.

Decoy receptor 1 (DCR1) promoter hypermethylation and response to irinotecan in metastatic colorectal cancer.

Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping.

Converting Cold into Hot Tumors by Combining Immunotherapies.

Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.

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Pharmacokinetics and excretion of ¹⁴C-Plitidepsin in patients with advanced cancer.