Publications

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30.

01-03-2016

Lung cancer (Amsterdam, Netherlands)

Crizotinib-induced fatal fulminant liver failure.

01-03-2016

European urology

ERBB2 Mutations Characterize a Subgroup of Muscle-invasive Bladder Cancers with Excellent Response to Neoadjuvant Chemotherapy.

01-03-2016

Haematologica

Treatment with the HIV protease inhibitor nelfinavir triggers the unfolded protein response and may overcome proteasome inhibitor resistance of multiple myeloma in combination with bortezomib: a phase I trial (SAKK 65/08).

01-03-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Fractures of thoracic vertebrae in patients with locally advanced non-small cell lung carcinoma treated with intensity modulated radiotherapy.

01-03-2016

PloS one

Targeted Next Generation Sequencing as a Reliable Diagnostic Assay for the Detection of Somatic Mutations in Tumours Using Minimal DNA Amounts from Formalin Fixed Paraffin Embedded Material.

27-02-2016

The Journal of biological chemistry

Rapid Remodeling of Invadosomes by Gi-coupled Receptors: DISSECTING THE ROLE OF Rho GTPases.

26-02-2016

Oncogene

Paclitaxel targets FOXM1 to regulate KIF20A in mitotic catastrophe and breast cancer paclitaxel resistance.

25-02-2016

Nature

Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.

25-02-2016

Molecular cell

Cohesin Releases DNA through Asymmetric ATPase-Driven Ring Opening.

18-02-2016

Molecular cell

Releasing Activity Disengages Cohesin's Smc3/Scc1 Interface in a Process Blocked by Acetylation.

18-02-2016

Molecular cell

PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining.

18-02-2016

Breast cancer research : BCR

Genetic predisposition to ductal carcinoma in situ of the breast.

17-02-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

First-in-Human Phase I Study of Lumretuzumab, a Glycoengineered Humanized Anti-HER3 Monoclonal Antibody, in Patients with Metastatic or Advanced HER3-Positive Solid Tumors.

15-02-2016

Behavioural brain research

Neurobiological changes by cytotoxic agents in mice.

15-02-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Exposure and Tumor Fn14 Expression as Determinants of Pharmacodynamics of the Anti-TWEAK Monoclonal Antibody RG7212 in Patients with Fn14-Positive Solid Tumors.

15-02-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for the tyrosine kinase inhibitor afatinib in mouse plasma using salting-out liquid-liquid extraction.

15-02-2016

The EMBO journal

Touch, act and go: landing and operating on nucleosomes.

15-02-2016

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Impact of Age at Primary Breast Cancer on Contralateral Breast Cancer Risk in BRCA1/2 Mutation Carriers.

10-02-2016

BMC Bioinformatics

Analysing multiple types of molecular profiles simultaneously: connecting the needles in the haystack

09-02-2016

Key

BMC cancer

Scenario drafting for early technology assessment of next generation sequencing in clinical oncology.

06-02-2016

BMC medical ethics

Exceptions to the rule of informed consent for research with an intervention.

06-02-2016

Circulation research

Genome-Wide Polyadenylation Maps Reveal Dynamic mRNA 3'-End Formation in the Failing Human Heart.

05-02-2016

Molecular cell

HELB Is a Feedback Inhibitor of DNA End Resection.

04-02-2016

Proceedings of the National Academy of Sciences of the United States of America

Enterovirus D68 receptor requirements unveiled by haploid genetics.

02-02-2016

British journal of cancer

Heterogeneity of luminal breast cancer characterised by immunohistochemical expression of basal markers.

02-02-2016

Genetics in medicine : official journal of the American College of Medical Genetics

Does rapid genetic counseling and testing in newly diagnosed breast cancer patients cause additional psychosocial distress? results from a randomized clinical trial.

01-02-2016

Cancer treatment reviews

Risk of subsequent gastrointestinal cancer among childhood cancer survivors: A systematic review.

01-02-2016

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Real-time in vivo assessment of radiofrequency ablation of human colorectal liver metastases using diffuse reflectance spectroscopy.

01-02-2016

Journal of virology

A Haploid Genetic Screen Identifies Heparan Sulfate Proteoglycans Supporting Rift Valley Fever Virus Infection.

01-02-2016

Investigational new drugs

Trastuzumab and bevacizumab combined with docetaxel, oxaliplatin and capecitabine as first-line treatment of advanced HER2-positive gastric cancer: a multicenter phase II study.

01-02-2016

European journal of cancer (Oxford, England : 1990)

Renal function, body surface area, and age are associated with risk of early-onset fluoropyrimidine-associated toxicity in patients treated with capecitabine-based anticancer regimens in daily clinical care.

01-02-2016

International journal of cancer

Ritonavir inhibits intratumoral docetaxel metabolism and enhances docetaxel antitumor activity in an immunocompetent mouse breast cancer model.

01-02-2016

DNA repair

The conserved molecular machinery in DNA mismatch repair enzyme structures.

01-02-2016

European journal of cancer (Oxford, England : 1990)

Perioperative treatment and radical cystectomy for bladder cancer--a population based trend analysis of 10,338 patients in the Netherlands.

01-02-2016

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Cytoreduction and hyperthermic intraperitoneal chemotherapy: The learning curve reassessed.

01-02-2016

PLoS genetics

3'UTR Shortening Potentiates MicroRNA-Based Repression of Pro-differentiation Genes in Proliferating Human Cells.

01-02-2016

Cancer discovery

DNA-Guided Precision Medicine for Cancer: A Case of Irrational Exuberance?

01-02-2016

World journal of urology

Neoadjuvant induction dose-dense MVAC for muscle invasive bladder cancer: efficacy and safety compared with classic MVAC and gemcitabine/cisplatin.

01-02-2016

Inflammatory bowel diseases

CD151 Regulates T-Cell Migration in Health and Inflammatory Bowel Disease.

01-02-2016

Oncoimmunology

Systemic inflammation: Cancer's long-distance reach to maximize metastasis.

01-02-2016

Nature biotechnology

Functional genetic screens for enhancer elements in the human genome using CRISPR-Cas9.

01-02-2016

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Correlates of physical activity among colorectal cancer survivors: results from the longitudinal population-based profiles registry.

01-02-2016

Journal of pharmaceutical and biomedical analysis

Liquid chromatography-tandem mass spectrometric assay for the simultaneous determination of the irreversible BTK inhibitor ibrutinib and its dihydrodiol-metabolite in plasma and its application in mouse pharmacokinetic studies.

25-01-2016

Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

23-01-2016

Journal for immunotherapy of cancer

Novel technologies and emerging biomarkers for personalized cancer immunotherapy.

21-01-2016

J Clin Oncol.

Radiation dose-response relationship for risk of coronary heart disease in survivors of Hodgkin lymphoma

20-01-2016

Key

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Radiation Dose-Response Relationship for Risk of Coronary Heart Disease in Survivors of Hodgkin Lymphoma.

20-01-2016

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Upfront Genotyping of DPYD*2A to Individualize Fluoropyrimidine Therapy: A Safety and Cost Analysis.

20-01-2016

Radiation oncology (London, England)

Lungtech, a phase II EORTC trial of SBRT for centrally located lung tumours - a clinical physics perspective.

20-01-2016