Publications

Annals of internal medicine

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

19-12-2017

Development (Cambridge, England)

Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.

15-12-2017

Science (New York, N.Y.)

Vasohibins encode tubulin detyrosinating activity.

15-12-2017

The EMBO journal

Cohesin: building loops, but not compartments.

15-12-2017

eLife

The Human Cell Atlas.

05-12-2017

Oncotarget

Prognostic factors in men with metastatic castration-resistant prostate cancer treated with cabazitaxel.

05-12-2017

Journal of the National Cancer Institute

Ovarian Function Recovery During Anastrozole in Breast Cancer Patients With Chemotherapy-Induced Ovarian Function Failure.

01-12-2017

JAMA oncology

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging: A Meta-analysis.

01-12-2017

Annals of oncology : official journal of the European Society for Medical Oncology

LAG-3: another brake to release in breast cancer?

01-12-2017

Annals of oncology : official journal of the European Society for Medical Oncology

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

01-12-2017

Clinical and translational radiation oncology

Retrospective methods to estimate radiation dose at the site of breast cancer development after Hodgkin lymphoma radiotherapy.

01-12-2017

European journal of nuclear medicine and molecular imaging

Validation and head-to-head comparison of three nomograms predicting probability of lymph node invasion of prostate cancer in patients undergoing extended and/or sentinel lymph node dissection.

01-12-2017

Journal of cancer survivorship : research and practice

Ambulant monitoring and web-accessible home-based exercise program during outpatient follow-up for resected lung cancer survivors: actual use and feasibility in clinical practice.

01-12-2017

Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research

Value of Implementation of Strategies to Increase the Adherence of Health Professionals and Cancer Survivors to Guideline-Based Physical Exercise.

01-12-2017

Cancer chemotherapy and pharmacology

Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

01-12-2017

International journal of epidemiology

Body mass index and breast cancer survival: a Mendelian randomization analysis.

01-12-2017

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Pembrolizumab in Small-Cell Lung Cancer: In Search of the Best Biomarker.

01-12-2017

Annals of oncology : official journal of the European Society for Medical Oncology

Molecular Tumor Boards: current practice and future needs.

01-12-2017

Investigational new drugs

Human mass balance study and metabolite profiling of ¹⁴C-niraparib, a novel poly(ADP-Ribose) polymerase (PARP)-1 and PARP-2 inhibitor, in patients with advanced cancer.

01-12-2017

JAMA oncology

Surveillance of Dutch Patients With Li-Fraumeni Syndrome: The LiFe-Guard Study.

01-12-2017

Oral oncology

Definitive (chemo)radiotherapy is a curative alternative for standard of care in advanced stage squamous cell carcinoma of the oral cavity.

01-12-2017

Thrombosis and haemostasis

Enrichment of Circulating Endothelial Cells by CD34 Microbeads Followed by Enumeration Using Flow Cytometry.

01-12-2017

Hepatology (Baltimore, Md.)

In vivo veritas: Finding novel genes involved in liver cancer through in vivo genetic screens.

01-12-2017

Breast cancer research and treatment

BRCA1-like profile is not significantly associated with survival benefit of non-myeloablative intensified chemotherapy in the GAIN randomized controlled trial.

01-12-2017

Journal of surgical oncology

Rapid genetic counseling and testing in newly diagnosed breast cancer: Patients' and health professionals' attitudes, experiences, and evaluation of effects on treatment decision making.

01-12-2017

The oncologist

A Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of Pictilisib in Combination with Erlotinib in Patients with Advanced Solid Tumors.

01-12-2017

International wound journal

Assessing and comparing the quality of wound centres: a literature review and benchmarking pilot.

01-12-2017

Reproductive biomedicine online

Low oocyte yield during IVF treatment and the risk of a trisomic pregnancy.

01-12-2017

Annals of surgical oncology

In Reply: Centralization of Upper Gastrointestinal Cancer Care Should Be Dictated by Quality of Care.

01-12-2017

Annals of surgical oncology

Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.

01-12-2017

Nature genetics

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

01-12-2017

European radiology

MRI surveillance for the detection of local recurrence in rectal cancer after transanal endoscopic microsurgery.

01-12-2017

Nature communications

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.

30-11-2017

Oncotarget

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

28-11-2017

ACS nano

A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux.

28-11-2017

ESMO open

Targeting immune checkpoints in breast cancer: an update of early results.

28-11-2017

Cell cycle (Georgetown, Tex.)

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

22-11-2017

Immunity

CD4⁺ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness.

21-11-2017

Lancet (London, England)

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial.

18-11-2017

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

An LC-MS/MS method for quantification of the active abiraterone metabolite Δ(4)-abiraterone (D4A) in human plasma.

15-11-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Selected Alkylating Agents Can Overcome Drug Tolerance of G₀-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice.

15-11-2017

International journal of radiation oncology, biology, physics

Breast Cancer Risk After Radiation Therapy for Hodgkin Lymphoma: Influence of Gonadal Hormone Exposure.

15-11-2017

BMJ open

Long-term prognosis of young breast cancer patients (≤40 years) who did not receive adjuvant systemic treatment: protocol for the PARADIGM initiative cohort study.

14-11-2017

F1000Research

Systematically linking tranSMART, Galaxy and EGA for reusing human translational research data.

11-11-2017

Journal of molecular biology

Regulation of USP7: A High Incidence of E3 Complexes.

10-11-2017

Swiss medical weekly

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue.

10-11-2017

Cell host & microbe

NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.

08-11-2017

Oncotarget

The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model.

07-11-2017

Oncotarget

The methylated way to translation.

07-11-2017

Breast cancer research : BCR

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

07-11-2017

Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.

Knockout of the Arp2/3 complex in epidermis causes a psoriasis-like disease hallmarked by hyperactivation of transcription factor Nrf2.

Vasohibins encode tubulin detyrosinating activity.

Cohesin: building loops, but not compartments.

The Human Cell Atlas.

Prognostic factors in men with metastatic castration-resistant prostate cancer treated with cabazitaxel.

Ovarian Function Recovery During Anastrozole in Breast Cancer Patients With Chemotherapy-Induced Ovarian Function Failure.

Baseline Surveillance in Li-Fraumeni Syndrome Using Whole-Body Magnetic Resonance Imaging: A Meta-analysis.

LAG-3: another brake to release in breast cancer?

DPYD genotype-guided dose individualization to improve patient safety of fluoropyrimidine therapy: call for a drug label update.

Retrospective methods to estimate radiation dose at the site of breast cancer development after Hodgkin lymphoma radiotherapy.

Validation and head-to-head comparison of three nomograms predicting probability of lymph node invasion of prostate cancer in patients undergoing extended and/or sentinel lymph node dissection.

Ambulant monitoring and web-accessible home-based exercise program during outpatient follow-up for resected lung cancer survivors: actual use and feasibility in clinical practice.

Value of Implementation of Strategies to Increase the Adherence of Health Professionals and Cancer Survivors to Guideline-Based Physical Exercise.

Exposure-survival analyses of pazopanib in renal cell carcinoma and soft tissue sarcoma patients: opportunities for dose optimization.

Body mass index and breast cancer survival: a Mendelian randomization analysis.

Pembrolizumab in Small-Cell Lung Cancer: In Search of the Best Biomarker.

Molecular Tumor Boards: current practice and future needs.

Human mass balance study and metabolite profiling of 14C-niraparib, a novel poly(ADP-Ribose) polymerase (PARP)-1 and PARP-2 inhibitor, in patients with advanced cancer.

Surveillance of Dutch Patients With Li-Fraumeni Syndrome: The LiFe-Guard Study.

Definitive (chemo)radiotherapy is a curative alternative for standard of care in advanced stage squamous cell carcinoma of the oral cavity.

Enrichment of Circulating Endothelial Cells by CD34 Microbeads Followed by Enumeration Using Flow Cytometry.

In vivo veritas: Finding novel genes involved in liver cancer through in vivo genetic screens.

BRCA1-like profile is not significantly associated with survival benefit of non-myeloablative intensified chemotherapy in the GAIN randomized controlled trial.

Rapid genetic counseling and testing in newly diagnosed breast cancer: Patients' and health professionals' attitudes, experiences, and evaluation of effects on treatment decision making.

A Phase I Dose-Escalation Study of the Safety and Pharmacokinetics of Pictilisib in Combination with Erlotinib in Patients with Advanced Solid Tumors.

Assessing and comparing the quality of wound centres: a literature review and benchmarking pilot.

Low oocyte yield during IVF treatment and the risk of a trisomic pregnancy.

In Reply: Centralization of Upper Gastrointestinal Cancer Care Should Be Dictated by Quality of Care.

Proteomic Features of Colorectal Cancer Identify Tumor Subtypes Independent of Oncogenic Mutations and Independently Predict Relapse-Free Survival.

Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

MRI surveillance for the detection of local recurrence in rectal cancer after transanal endoscopic microsurgery.

Discovery of naturally occurring ESR1 mutations in breast cancer cell lines modelling endocrine resistance.

PHIP - a novel candidate breast cancer susceptibility locus on 6q14.1.

A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux.

Targeting immune checkpoints in breast cancer: an update of early results.

H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2.

CD4+ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness.

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): a randomised, double-blind, phase 3 trial.

An LC-MS/MS method for quantification of the active abiraterone metabolite Δ(4)-abiraterone (D4A) in human plasma.

Selected Alkylating Agents Can Overcome Drug Tolerance of G0-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice.

Breast Cancer Risk After Radiation Therapy for Hodgkin Lymphoma: Influence of Gonadal Hormone Exposure.

Long-term prognosis of young breast cancer patients (≤40 years) who did not receive adjuvant systemic treatment: protocol for the PARADIGM initiative cohort study.

Systematically linking tranSMART, Galaxy and EGA for reusing human translational research data.

Regulation of USP7: A High Incidence of E3 Complexes.

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue.

NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.

The adaptive immune system promotes initiation of prostate carcinogenesis in a human c-Myc transgenic mouse model.

The methylated way to translation.

Reproductive profiles and risk of breast cancer subtypes: a multi-center case-only study.

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Human mass balance study and metabolite profiling of ¹⁴C-niraparib, a novel poly(ADP-Ribose) polymerase (PARP)-1 and PARP-2 inhibitor, in patients with advanced cancer.

CD4⁺ T Cell Help Confers a Cytotoxic T Cell Effector Program Including Coinhibitory Receptor Downregulation and Increased Tissue Invasiveness.

Selected Alkylating Agents Can Overcome Drug Tolerance of G₀-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice.