Publications

Breast cancer research : BCR

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women.

11-11-2016

Cell metabolism

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

08-11-2016

Oncotarget

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.

08-11-2016

BMC cancer

A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation?

08-11-2016

Cold Spring Harbor symposia on quantitative biology

Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.

07-11-2016

Cancer treatment reviews

Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity - Ready for clinical practice?

01-11-2016

Clinical pharmacokinetics

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

01-11-2016

Urologic oncology

Prostate cancer survivors with a passive role preference in treatment decision-making are less satisfied with information received: Results from the PROFILES registry.

01-11-2016

EMBO reports

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

01-11-2016

Acta oncologica (Stockholm, Sweden)

Prospective Dutch colorectal cancer cohort: an infrastructure for long-term observational, prognostic, predictive and (randomized) intervention research.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

An MRI-based mid-ventilation approach for radiotherapy of the liver.

01-11-2016

International journal of radiation oncology, biology, physics

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis.

01-11-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

01-11-2016

AJR. American journal of roentgenology

Diagnostic Accuracy of CT for Local Staging of Colon Cancer: A Systematic Review and Meta-Analysis.

01-11-2016

International journal of radiation oncology, biology, physics

Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.

01-11-2016

Journal of the National Cancer Institute

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

01-11-2016

Lasers in surgery and medicine

In vivo tumor identification of colorectal liver metastases with diffuse reflectance and fluorescence spectroscopy.

01-11-2016

European journal of cancer (Oxford, England : 1990)

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

01-11-2016

JAMA oncology

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

01-11-2016

European journal of cell biology

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

01-11-2016

European urology

The Effect of Salvage Radiotherapy and its Timing on the Health-related Quality of Life of Prostate Cancer Patients.

01-11-2016

Cancer treatment reviews

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Consensus opinion on MRI simulation for external beam radiation treatment planning.

01-11-2016

Frontiers in oncology

The MRI-Linear Accelerator Consortium: Evidence-Based Clinical Introduction of an Innovation in Radiation Oncology Connecting Researchers, Methodology, Data Collection, Quality Assurance, and Technical Development.

30-10-2016

Methods in molecular biology (Clifton, N.J.)

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

28-10-2016

Epigenetics & chromatin

High-throughput assessment of context-dependent effects of chromatin proteins.

26-10-2016

Journal of pharmaceutical and biomedical analysis

Recent developments in the chromatographic bioanalysis of approved kinase inhibitor drugs in oncology.

25-10-2016

JAMA

Breast Cancer Risk After Ovarian Stimulation for In Vitro Fertilization-Reply.

25-10-2016

Oncotarget

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

25-10-2016

BMC systems biology

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

21-10-2016

Breast cancer research : BCR

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

18-10-2016

The Journal of experimental medicine

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

17-10-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

15-10-2016

Cancer research

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

15-10-2016

Oncotarget

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

11-10-2016

Cancer cell

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

10-10-2016

Cancer cell

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

10-10-2016

Journal of controlled release : official journal of the Controlled Release Society

Inherent formulation issues of kinase inhibitors.

10-10-2016

Nature

X-ray structures define human P2X(3) receptor gating cycle and antagonist action.

06-10-2016

Oncogene

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

06-10-2016

American journal of human genetics

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

06-10-2016

Breast cancer research : BCR

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

03-10-2016

Cancer

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

01-10-2016

Breast (Edinburgh, Scotland)

Don't forget the dentist: Dental care use and needs of women with breast cancer.

01-10-2016

Urologic oncology

Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.

01-10-2016

Cancer chemotherapy and pharmacology

Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.

01-10-2016

The oncologist

Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges.

01-10-2016

Gastroenterology

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

01-10-2016

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women.

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.

A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation?

Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.

Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity - Ready for clinical practice?

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

Prostate cancer survivors with a passive role preference in treatment decision-making are less satisfied with information received: Results from the PROFILES registry.

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

Prospective Dutch colorectal cancer cohort: an infrastructure for long-term observational, prognostic, predictive and (randomized) intervention research.

An MRI-based mid-ventilation approach for radiotherapy of the liver.

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis.

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

Diagnostic Accuracy of CT for Local Staging of Colon Cancer: A Systematic Review and Meta-Analysis.

Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

In vivo tumor identification of colorectal liver metastases with diffuse reflectance and fluorescence spectroscopy.

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

The Effect of Salvage Radiotherapy and its Timing on the Health-related Quality of Life of Prostate Cancer Patients.

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique.

Consensus opinion on MRI simulation for external beam radiation treatment planning.

The MRI-Linear Accelerator Consortium: Evidence-Based Clinical Introduction of an Innovation in Radiation Oncology Connecting Researchers, Methodology, Data Collection, Quality Assurance, and Technical Development.

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

High-throughput assessment of context-dependent effects of chromatin proteins.

Recent developments in the chromatographic bioanalysis of approved kinase inhibitor drugs in oncology.

Breast Cancer Risk After Ovarian Stimulation for In Vitro Fertilization-Reply.

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Inherent formulation issues of kinase inhibitors.

X-ray structures define human P2X(3) receptor gating cycle and antagonist action.

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

Don't forget the dentist: Dental care use and needs of women with breast cancer.

Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.

Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.

Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges.

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

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