Publications

Biomedical optics express

Using DRS during breast conserving surgery: identifying robust optical parameters and influence of inter-patient variation.

Journal of medical genetics

PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS.

The Lancet. Oncology

Biomarkers for outcome upon MAPK inhibition in melanoma.

Journal of structural biology

A conserved two-step binding for the UAF1 regulator to the USP12 deubiquitinating enzyme.

Breast (Edinburgh, Scotland)

Low risk of recurrence in elderly patients treated with breast conserving therapy in a single institute.

Journal of mammary gland biology and neoplasia

p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice.

European journal of cancer (Oxford, England : 1990)

Reference data of the European Organisation for Research and Treatment of Cancer (EORTC) QLQ-CIPN20 Questionnaire in the general Dutch population.

Journal of immunology (Baltimore, Md. : 1950)

GATA1-Deficient Dendritic Cells Display Impaired CCL21-Dependent Migration toward Lymph Nodes Due to Reduced Levels of Polysialic Acid.

European journal of nuclear medicine and molecular imaging

Crossing technological frontiers in radioguided intervention.

Virchows Archiv : an international journal of pathology

A critical evaluation of lymph node ratio in head and neck cancer.

Nature cell biology

Lgr6 labels a rare population of mammary gland progenitor cells that are able to originate luminal mammary tumours.

Clinical oncology (Royal College of Radiologists (Great Britain))

Functional Imaging in Radiotherapy in the Netherlands: Availability and Impact on Clinical Practice.

Proteins

Structural basis of reversine selectivity in inhibiting Mps1 more potently than aurora B kinase.

BMC cancer

Design of a randomized controlled trial of Internet-based cognitive behavioral therapy for treatment-induced menopausal symptoms in breast cancer survivors.

25-11-2016

BMC medical informatics and decision making

Operations research for resource planning and -use in radiotherapy: a literature review.

25-11-2016

Scientific reports

Logic models to predict continuous outputs based on binary inputs with an application to personalized cancer therapy.

23-11-2016

ESMO open

ESMO / ASCO Recommendations for a Global Curriculum in Medical Oncology Edition 2016.

16-11-2016

eLife

Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening.

Clinical cancer research : an official journal of the American Association for Cancer Research

Focusing on Core Patient-Reported Outcomes in Cancer Clinical Trials-Letter.

Cardio-oncology (London, England)

Cardiovascular co-morbidity in cancer patients: the role of psychological distress.

Scientific reports

rs2735383, located at a microRNA binding site in the 3'UTR of NBS1, is not associated with breast cancer risk.

Clinical cancer research : an official journal of the American Association for Cancer Research

Baseline Biomarkers for Outcome of Melanoma Patients Treated with Pembrolizumab.

Breast cancer research : BCR

Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women.

11-11-2016

Cell metabolism

LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells.

08-11-2016

Oncotarget

Genomic profiling of stage II and III colon cancers reveals APC mutations to be associated with survival in stage III colon cancer patients.

08-11-2016

BMC cancer

A case series of intestinal adenomatous polyposis of unidentified etiology; a late effect of irradiation?

08-11-2016

Cold Spring Harbor symposia on quantitative biology

Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.

07-11-2016

Cancer treatment reviews

Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity - Ready for clinical practice?

Clinical pharmacokinetics

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.

European journal of cancer (Oxford, England : 1990)

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

Urologic oncology

Prostate cancer survivors with a passive role preference in treatment decision-making are less satisfied with information received: Results from the PROFILES registry.

EMBO reports

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

Acta oncologica (Stockholm, Sweden)

Prospective Dutch colorectal cancer cohort: an infrastructure for long-term observational, prognostic, predictive and (randomized) intervention research.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

An MRI-based mid-ventilation approach for radiotherapy of the liver.

International journal of radiation oncology, biology, physics

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis.

Clinical cancer research : an official journal of the American Association for Cancer Research

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

AJR. American journal of roentgenology

Diagnostic Accuracy of CT for Local Staging of Colon Cancer: A Systematic Review and Meta-Analysis.

International journal of radiation oncology, biology, physics

Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.

Journal of the National Cancer Institute

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

Lasers in surgery and medicine

In vivo tumor identification of colorectal liver metastases with diffuse reflectance and fluorescence spectroscopy.

European journal of cancer (Oxford, England : 1990)

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

European journal of cancer (Oxford, England : 1990)

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

JAMA oncology

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

European journal of cell biology

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

European urology

The Effect of Salvage Radiotherapy and its Timing on the Health-related Quality of Life of Prostate Cancer Patients.

Cancer treatment reviews

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Consensus opinion on MRI simulation for external beam radiation treatment planning.