Publications

Oncotarget

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

25-10-2016

BMC systems biology

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

21-10-2016

Breast cancer research : BCR

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

18-10-2016

The Journal of experimental medicine

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

17-10-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

15-10-2016

Cancer research

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

15-10-2016

Oncotarget

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

11-10-2016

Cancer cell

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

10-10-2016

Cancer cell

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

10-10-2016

Journal of controlled release : official journal of the Controlled Release Society

Inherent formulation issues of kinase inhibitors.

10-10-2016

Nature

X-ray structures define human P2X(3) receptor gating cycle and antagonist action.

06-10-2016

Oncogene

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

06-10-2016

American journal of human genetics

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

06-10-2016

Breast cancer research : BCR

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

03-10-2016

Cancer

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

01-10-2016

Breast (Edinburgh, Scotland)

Don't forget the dentist: Dental care use and needs of women with breast cancer.

01-10-2016

Urologic oncology

Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.

01-10-2016

Cancer chemotherapy and pharmacology

Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.

01-10-2016

The oncologist

Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges.

01-10-2016

Gastroenterology

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

01-10-2016

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Toward (Hybrid) Navigation of a Fluorescence Camera in an Open Surgery Setting.

01-10-2016

Minerva urologica e nefrologica = The Italian journal of urology and nephrology

Stapling for prostate pedicle management during robot-assisted radical prostatectomy.

01-10-2016

Acta diabetologica

Impact of cancer diagnosis and treatment on glycaemic control among individuals with colorectal cancer using glucose-lowering drugs.

01-10-2016

Assay and drug development technologies

HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets.

01-10-2016

European journal of human genetics : EJHG

Unsolicited findings of next-generation sequencing for tumor analysis within a Dutch consortium: clinical daily practice reconsidered.

01-10-2016

Journal of clinical pharmacology

The Use of Dried Blood Spots for Pharmacokinetic Monitoring of Vemurafenib Treatment in Melanoma Patients.

01-10-2016

Molecular endocrinology (Baltimore, Md.)

The Estrogen Receptor α-Cistrome Beyond Breast Cancer.

01-10-2016

Breast cancer research and treatment

Subsequent risk of ipsilateral and contralateral invasive breast cancer after treatment for ductal carcinoma in situ: incidence and the effect of radiotherapy in a population-based cohort of 10,090 women.

01-10-2016

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Erratum to: QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30.

01-10-2016

Breast (Edinburgh, Scotland)

Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study.

01-10-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Multiple training interventions significantly improve reproducibility of PET/CT-based lung cancer radiotherapy target volume delineation using an IAEA study protocol.

01-10-2016

Journal of cancer survivorship : research and practice

Illness perceptions are associated with mortality among 1552 colorectal cancer survivors: a study from the population-based PROFILES registry.

01-10-2016

Journal of pain and symptom management

Cognitive Impairment in a Subset of Breast Cancer Patients After Systemic Therapy-Results From a Longitudinal Study.

01-10-2016

Investigational new drugs

Pharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumors.

01-10-2016

The journal of pathology. Clinical research

FGFR1, 2 and 3 protein overexpression and molecular aberrations of FGFR3 in early stage non-small cell lung cancer.

01-10-2016

Oncotarget

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.

27-09-2016

British journal of cancer

Increased pancreatic cancer risk following radiotherapy for testicular cancer.

27-09-2016

Nature communications

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.

26-09-2016

International journal of pharmaceutics

Pharmaceutical development of an oral tablet formulation containing a spray dried amorphous solid dispersion of docetaxel or paclitaxel.

25-09-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy.

15-09-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for the T790M mutant EGFR inhibitor osimertinib (AZD9291) in human plasma.

15-09-2016

International journal of cancer

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.

15-09-2016

Oncogene

Targeting the RB-E2F pathway in breast cancer.

15-09-2016

BMC health services research

Quality assessments for cancer centers in the European Union.

07-09-2016

Scientific reports

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

07-09-2016

Nature communications

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

07-09-2016

BMC cancer

Cost-effectiveness and resource use of implementing MRI-guided NACT in ER-positive/HER2-negative breast cancers in The Netherlands.

05-09-2016

The Journal of biological chemistry

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.

02-09-2016

Methods in molecular biology (Clifton, N.J.)

Pooled shRNA Screening in Mammalian Cells as a Functional Genomic Discovery Platform.

02-09-2016

Methods in molecular biology (Clifton, N.J.)

Purification of Immune Cell Populations from Freshly Isolated Murine Tumors and Organs by Consecutive Magnetic Cell Sorting and Multi-parameter Flow Cytometry-Based Sorting.

02-09-2016

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

Inherent formulation issues of kinase inhibitors.

X-ray structures define human P2X(3) receptor gating cycle and antagonist action.

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

Don't forget the dentist: Dental care use and needs of women with breast cancer.

Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.

Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.

Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges.

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

Toward (Hybrid) Navigation of a Fluorescence Camera in an Open Surgery Setting.

Stapling for prostate pedicle management during robot-assisted radical prostatectomy.

Impact of cancer diagnosis and treatment on glycaemic control among individuals with colorectal cancer using glucose-lowering drugs.

HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets.

Unsolicited findings of next-generation sequencing for tumor analysis within a Dutch consortium: clinical daily practice reconsidered.

The Use of Dried Blood Spots for Pharmacokinetic Monitoring of Vemurafenib Treatment in Melanoma Patients.

The Estrogen Receptor α-Cistrome Beyond Breast Cancer.

Subsequent risk of ipsilateral and contralateral invasive breast cancer after treatment for ductal carcinoma in situ: incidence and the effect of radiotherapy in a population-based cohort of 10,090 women.

Erratum to: QLU-C10D: a health state classification system for a multi-attribute utility measure based on the EORTC QLQ-C30.

Toxicity of dual HER2-blockade with pertuzumab added to anthracycline versus non-anthracycline containing chemotherapy as neoadjuvant treatment in HER2-positive breast cancer: The TRAIN-2 study.

Multiple training interventions significantly improve reproducibility of PET/CT-based lung cancer radiotherapy target volume delineation using an IAEA study protocol.

Illness perceptions are associated with mortality among 1552 colorectal cancer survivors: a study from the population-based PROFILES registry.

Cognitive Impairment in a Subset of Breast Cancer Patients After Systemic Therapy-Results From a Longitudinal Study.

Pharmacokinetics and excretion of (14)C-omacetaxine in patients with advanced solid tumors.

FGFR1, 2 and 3 protein overexpression and molecular aberrations of FGFR3 in early stage non-small cell lung cancer.

Secretome proteomics reveals candidate non-invasive biomarkers of BRCA1 deficiency in breast cancer.

Increased pancreatic cancer risk following radiotherapy for testicular cancer.

Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration.

Pharmaceutical development of an oral tablet formulation containing a spray dried amorphous solid dispersion of docetaxel or paclitaxel.

WRN Promoter CpG Island Hypermethylation Does Not Predict More Favorable Outcomes for Patients with Metastatic Colorectal Cancer Treated with Irinotecan-Based Therapy.

Liquid chromatography-tandem mass spectrometric assay for the T790M mutant EGFR inhibitor osimertinib (AZD9291) in human plasma.

Fine-scale mapping of 8q24 locus identifies multiple independent risk variants for breast cancer.

Targeting the RB-E2F pathway in breast cancer.

Quality assessments for cancer centers in the European Union.

Fine scale mapping of the 17q22 breast cancer locus using dense SNPs, genotyped within the Collaborative Oncological Gene-Environment Study (COGs).

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast-ovarian cancer susceptibility locus.

Cost-effectiveness and resource use of implementing MRI-guided NACT in ER-positive/HER2-negative breast cancers in The Netherlands.

The Structure of the Plakin Domain of Plectin Reveals an Extended Rod-like Shape.

Pooled shRNA Screening in Mammalian Cells as a Functional Genomic Discovery Platform.

Purification of Immune Cell Populations from Freshly Isolated Murine Tumors and Organs by Consecutive Magnetic Cell Sorting and Multi-parameter Flow Cytometry-Based Sorting.

This site uses cookies