Publications

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

The impact of Organic Anion-Transporting Polypeptides (OATPs) on disposition and toxicity of antitumor drugs: Insights from knockout and humanized mice.

Breast cancer research and treatment

The effect of trastuzumab-based chemotherapy in small node-negative HER2-positive breast cancer.

Investigative radiology

Prediction Model For Extensive Ductal Carcinoma In Situ Around Early-Stage Invasive Breast Cancer.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Utilization of supportive care by survivors of colorectal cancer: results from the PROFILES registry.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Prevalence of swallowing and speech problems in daily life after chemoradiation for head and neck cancer based on cut-off scores of the patient-reported outcome measures SWAL-QOL and SHI.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dynamic contrast-enhanced MRI for treatment response assessment in patients with oesophageal cancer receiving neoadjuvant chemoradiotherapy.

Annals of oncology : official journal of the European Society for Medical Oncology

Tumor heterogeneity of fibroblast growth factor receptor 3 (FGFR3) mutations in invasive bladder cancer: implications for perioperative anti-FGFR3 treatment.

Seminars in radiation oncology

Magnetic Resonance Imaging and Other Imaging Modalities in Diagnostic and Tumor Response Evaluation.

European radiology

MRI and diffusion-weighted MRI to diagnose a local tumour regrowth during long-term follow-up of rectal cancer patients treated with organ preservation after chemoradiotherapy.

European journal of nuclear medicine and molecular imaging

Multimodal hybrid imaging agents for sentinel node mapping as a means to (re)connect nuclear medicine to advances made in robot-assisted surgery.

Cell

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport.

30-06-2016

Ecancermedicalscience

The steady progress of targeted therapies, promising advances for lung cancer.

29-06-2016

Cell reports

BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts.

28-06-2016

Proceedings of the National Academy of Sciences of the United States of America

Defining chromosomal translocation risks in cancer.

28-06-2016

Cancer informatics

The Melanoma MAICare Framework: A Microsimulation Model for the Assessment of Individualized Cancer Care.

28-06-2016

Nederlands tijdschrift voor geneeskunde

[Radiotherapy in Europe].

24-06-2016

Acta oncologica (Stockholm, Sweden)

Neurocognitive function of lymphoma patients after treatment with chemotherapy.

23-06-2016

Oncotarget

Intrinsic resistance to PIM kinase inhibition in AML through p38α-mediated feedback activation of mTOR signaling.

21-06-2016

Breast cancer research : BCR

Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus.

21-06-2016

Trials

A phase I followed by a randomized phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy versus capecitabine in BRCA1- or BRCA2-mutated HER2-negative advanced breast cancer as first line treatment (REVIVAL): study protocol for a randomized controlled trial.

21-06-2016

Scientific reports

OncoScape: Exploring the cancer aberration landscape by genomic data fusion.

20-06-2016

JAMA

Ovarian stimulation for in vitro fertilization and long-term risk of breast cancer

19-06-2016

Key Publication

mSphere

A Single Residue in Ebola Virus Receptor NPC1 Influences Cellular Host Range in Reptiles.

16-06-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

TAS-102 for Treatment of Advanced Colorectal Cancers That Are No Longer Responding to Other Therapies.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for ponatinib and N-desmethyl ponatinib in mouse plasma.

Genes & development

Modeling invasive lobular breast carcinoma by CRISPR/Cas9-mediated somatic genome editing of the mammary gland.

Clinical cancer research : an official journal of the American Association for Cancer Research

Baseline Peripheral Blood Biomarkers Associated with Clinical Outcome of Advanced Melanoma Patients Treated with Ipilimumab.

BMC cancer

Variation in use of targeted therapies for metastatic renal cell carcinoma: Results from a Dutch population-based registry.

11-06-2016

Science (New York, N.Y.)

Targeting of cancer neoantigens with donor-derived T cell receptor repertoires.

10-06-2016

Nature communications

Cholesterol and ORP1L-mediated ER contact sites control autophagosome transport and fusion with the endocytic pathway.

10-06-2016

Health and quality of life outcomes

Thresholds for clinical importance for four key domains of the EORTC QLQ-C30: physical functioning, emotional functioning, fatigue and pain.

07-06-2016

Oncotarget

Neoadjuvant tamoxifen synchronizes ERα binding and gene expression profiles related to outcome and proliferation.

07-06-2016

Journal of pharmaceutical and biomedical analysis

Simultaneous quantification of dabrafenib and trametinib in human plasma using high-performance liquid chromatography-tandem mass spectrometry.

05-06-2016

Nature

Landscape of somatic mutations in 560 breast cancer whole-genome sequences.

02-06-2016

Nucleic acids research

PrimPol prevents APOBEC/AID family mediated DNA mutagenesis.

02-06-2016

European journal of immunology

Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy.

Acta oncologica (Stockholm, Sweden)

Time trends in axilla management among early breast cancer patients: Persisting major variation in clinical practice across European centers.

Gut

Development and validation of the WASP classification system for optical diagnosis of adenomas, hyperplastic polyps and sessile serrated adenomas/polyps.

AJR. American journal of roentgenology

Evaluation of a Hanging-Breast PET System for Primary Tumor Visualization in Patients With Stage I-III Breast Cancer: Comparison With Standard PET/CT.

Nature methods

siFLIM: single-image frequency-domain FLIM provides fast and photon-efficient lifetime data.

Frontiers in cellular neuroscience

ATP Released by Injured Neurons Activates Schwann Cells.

Neuro-oncology

EpCAM-based flow cytometry in cerebrospinal fluid greatly improves diagnostic accuracy of leptomeningeal metastases from epithelial tumors.

The British journal of radiology

Hybrid surgical guidance based on the integration of radionuclear and optical technologies.

Annals of oncology : official journal of the European Society for Medical Oncology

Targeted treatment and immunotherapy in leptomeningeal metastases from melanoma.

Cancer chemotherapy and pharmacology

A phase 0 clinical trial of novel candidate extended-release formulations of capecitabine.

Current opinion in structural biology

Recombinant cloning strategies for protein expression.

Cancer immunology, immunotherapy : CII

Concomitant targeting of programmed death-1 (PD-1) and CD137 improves the efficacy of radiotherapy in a mouse model of human BRAFV600-mutant melanoma.

Investigational new drugs

Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison.

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Feasibility and impact of a dedicated multidisciplinary rehabilitation program on health-related quality of life in advanced head and neck cancer patients.