Publications

Cancer cell

Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer.

01-06-2004

Clinical cancer research : an official journal of the American Association for Cancer Research

A Phase I and pharmacological study with imidazolium-trans-DMSO-imidazole-tetrachlororuthenate, a novel ruthenium anticancer agent.

01-06-2004

Journal of the American Geriatrics Society

Antihypertensive medications and differences in muscle mass in older persons: the Health, Aging and Body Composition Study.

01-06-2004

Science (New York, N.Y.)

Antigen bias in T cell cross-priming.

28-05-2004

Clinical cancer research : an official journal of the American Association for Cancer Research

A Phase I and pharmacological study of the platinum polymer AP5280 given as an intravenous infusion once every 3 weeks in patients with solid tumors.

15-05-2004

European journal of cancer (Oxford, England : 1990)

Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein.

01-05-2004

Cell cycle (Georgetown, Tex.)

Unraveling human tumor suppressor pathways: a tale of the INK4A locus.

01-05-2004

British journal of cancer

Clinical outcome of prophylactic oophorectomy in BRCA1/BRCA2 mutation carriers and events during follow-up.

19-04-2004

The New England journal of medicine

Good news for gene therapy.

15-04-2004

Clinical cancer research : an official journal of the American Association for Cancer Research

Bayesian pharmacokinetically guided dosing of paclitaxel in patients with non-small cell lung cancer.

01-04-2004

Breast cancer research and treatment

Insulin-like growth factor (IGF)-system mRNA quantities in normal and tumor breast tissue of women with sporadic and familial breast cancer risk.

01-04-2004

Investigational new drugs

Pharmacokinetic drug-drug interaction of the novel anticancer agent E7070 and acenocoumarol.

01-04-2004

Journal of pharmacokinetics and pharmacodynamics

Integrated Population Pharmacokinetic Model of both cyclophosphamide and thiotepa suggesting a mutual drug-drug interaction.

01-04-2004

Journal of mass spectrometry : JMS

Simple and sensitive liquid chromatographic quantitative analysis of the novel marine anticancer drug Yondelis (ET-743, trabectedin) in human plasma using column switching and tandem mass spectrometric detection.

01-04-2004

Human reproduction (Oxford, England)

The number of retrieved oocytes does not decrease during consecutive gonadotrophin-stimulated IVF cycles.

01-04-2004

Biophysical journal

Correcting confocal acquisition to optimize imaging of fluorescence resonance energy transfer by sensitized emission.

01-04-2004

Neuron

Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures.

25-03-2004

Nature

A large-scale RNAi screen in human cells identifies new components of the p53 pathway.

25-03-2004

Nederlands tijdschrift voor geneeskunde

[Genetic research with stored human tissue: a coding procedure with optimal use of information and protection of privacy].

20-03-2004

Cancer research

Human telomerase reverse transcriptase-transduced human cytotoxic T cells suppress the growth of human melanoma in immunodeficient mice.

15-03-2004

The Journal of biological chemistry

High incidence of thymic epithelial tumors in E2F2 transgenic mice.

12-03-2004

Journal of mass spectrometry : JMS

Quantitative analysis of the novel anticancer drug ABT-518, a matrix metalloproteinase inhibitor, plus the screening of six metabolites in human plasma using high-performance liquid chromatography coupled with electrospray tandem mass spectrometry.

01-03-2004

Journal of mass spectrometry : JMS

Simultaneous quantification of cyclophosphamide, 4-hydroxycyclophosphamide, N,N',N"-triethylenethiophosphoramide (thiotepa) and N,N',N"-triethylenephosphoramide (tepa) in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.

01-03-2004

Molecular biology of the cell

Role of binding of plectin to the integrin beta4 subunit in the assembly of hemidesmosomes.

01-03-2004

British journal of cancer

N-hexanoyl-sphingomyelin potentiates in vitro doxorubicin cytotoxicity by enhancing its cellular influx.

23-02-2004

Journal of immunology (Baltimore, Md. : 1950)

The impact of self-tolerance on the polyclonal CD8+ T cell repertoire.

15-02-2004

Medical physics

Leaf trajectory verification during dynamic intensity modulated radiotherapy using an amorphous silicon flat panel imager.

01-02-2004

Cancer causes & control : CCC

A cohort study of cancer mortality among Biology Research Laboratory workers in The Netherlands.

01-02-2004

Medical physics

Dose-response and ghosting effects of an amorphous silicon electronic portal imaging device.

01-02-2004

Cancer chemotherapy and pharmacology

The influence of the P-glycoprotein inhibitor zosuquidar trihydrochloride (LY335979) on the brain penetration of paclitaxel in mice.

01-02-2004

Clinical pharmacokinetics

Population pharmacokinetics and pharmacodynamics of mitomycin during intraoperative hyperthermic intraperitoneal chemotherapy.

30-01-2004

Genome research

A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization

01-01-2004

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Differentiation-associated staining with anti-pimonidazole antibodies in head and neck tumors.

01-01-2004

Handbook of experimental pharmacology

Hemidesmosomes: molecular organization and their importance for cell adhesion and disease.

01-01-2004

Analytical biochemistry

Development and validation of a method to determine the unbound paclitaxel fraction in human plasma.

01-01-2004

The Journal of pharmacology and experimental therapeutics

Pharmacological and physiological functions of the polyspecific organic cation transporters: OCT1, 2, and 3 (SLC22A1-3).

01-01-2004

Radiation research

Identification of differentially expressed genes in mouse kidney after irradiation using microarray analysis.

01-01-2004

Breast cancer research and treatment

Excess risk for contralateral breast cancer in CHEK2*1100delC germline mutation carriers.

01-01-2004

Proceedings of the National Academy of Sciences of the United States of America

Gene expression profiles of primary breast tumors maintained in distant metastases.

23-12-2003

Journal of chromatography. A

Development and validation of a liquid chromatography-ultraviolet absorbance detection assay using derivatisation for the novel marine anticancer agent ES-285 x HCl [(2S,3R)-2-amino-3-octadecanol hydrochloride] and its pharmaceutical dosage form.

12-12-2003

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of zosuquidar trihydrochloride (LY335979) in small volumes of human and murine plasma by ion-pairing reversed-phase high-performance liquid chromatography.

05-12-2003

Apoptosis : an international journal on programmed cell death

The anti-cancer drug etoposide can induce caspase-8 processing and apoptosis in the absence of CD95 receptor-ligand interaction.

04-12-2003

The Journal of pathology

Integrins in regulation of tissue development and function.

01-12-2003

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Thallium-201-chloride scintigraphy in staging and monitoring radiotherapy response in follicular lymphoma patients.

01-12-2003

Genes & development

Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location.

15-11-2003

The Journal of experimental medicine

CD27 promotes survival of activated T cells and complements CD28 in generation and establishment of the effector T cell pool.

03-11-2003

British journal of cancer

P-glycoprotein and Mrp1 collectively protect the bone marrow from vincristine-induced toxicity in vivo.

03-11-2003

Cancer research

The generation of a conditional reporter that enables bioluminescence imaging of Cre/loxP-dependent tumorigenesis in mice.

01-11-2003

Molecular and cellular biology

Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.

01-11-2003

The Journal of biological chemistry

Calcium signaling regulates translocation and activation of Rac.

10-10-2003