Publications

Breast cancer research and treatment

A breast cancer gene signature for indolent disease.

Annals of oncology : official journal of the European Society for Medical Oncology

Dabrafenib plus trametinib versus dabrafenib monotherapy in patients with metastatic BRAF V600E/K-mutant melanoma: long-term survival and safety analysis of a phase 3 study.

Human reproduction (Oxford, England)

Effects of long-term exogenous testosterone administration on ovarian morphology, determined by transvaginal (3D) ultrasound in female-to-male transsexuals.

Menopause (New York, N.Y.)

An Internet-based cognitive behavioral therapy for treatment-induced menopausal symptoms in breast cancer survivors: results of a pilot study.

BMC cancer

Clinically node negative breast cancer patients undergoing breast conserving therapy, sentinel lymph node procedure versus follow-up: a Dutch randomized controlled multicentre trial (BOOG 2013-08).

European urology

Multispectral Fluorescence Imaging During Robot-assisted Laparoscopic Sentinel Node Biopsy: A First Step Towards a Fluorescence-based Anatomic Roadmap.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Changes in nationwide use of preoperative radiotherapy for rectal cancer after revision of the national colorectal cancer guideline.

Physics in medicine and biology

The feasibility of manual parameter tuning for deformable breast MR image registration from a multi-objective optimization perspective.

Cell chemical biology

Proteasome Activation by Small Molecules.

Journal of medical Internet research

The Effectiveness of Information Technology-Supported Shared Care for Patients With Chronic Disease: A Systematic Review.

JAMA

Risks of Breast, Ovarian, and Contralateral Breast Cancer for BRCA1 and BRCA2 Mutation Carriers.

Cell reports

p53 Prohibits Propagation of Chromosome Segregation Errors that Produce Structural Aneuploidies.

BMJ open

Return to work of cancer patients after a multidisciplinary intervention including occupational counselling and physical exercise in cancer patients: a prospective study in the Netherlands.

Physics in medicine and biology

Repeatability of dose painting by numbers treatment planning in prostate cancer radiotherapy based on multiparametric magnetic resonance imaging.

Oncotarget

Stable aneuploid tumors cells are more sensitive to TTK inhibition than chromosomally unstable cell lines.

Frontiers in genetics

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction.

Nature

Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.

Physics in medicine and biology

Reducing 4DCBCT imaging time and dose: the first implementation of variable gantry speed 4DCBCT on a linear accelerator.

Gut

RSPO3 expands intestinal stem cell and niche compartments and drives tumorigenesis.

European journal of cancer (Oxford, England : 1990)

Accuracy of the online prognostication tools PREDICT and Adjuvant! for early-stage breast cancer patients younger than 50 years.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose to heart substructures is associated with non-cancer death after SBRT in stage I-II NSCLC patients.

Journal of cell communication and signaling

Tamoxifen for induction of Cre-recombination may confound fibrosis studies in female mice.

Nature genetics

Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Genome research

Small chromosomal regions position themselves autonomously according to their chromatin class.

BMJ (Clinical research ed.)

Which are the best conservative interventions for lymphoedema after breast cancer surgery?

Hematological oncology

Late sequelae in Hodgkin lymphoma survivors.

Clinica chimica acta; international journal of clinical chemistry

A serum and platelet-rich plasma serotonin assay using liquid chromatography tandem mass spectrometry for monitoring of neuroendocrine tumor patients.

Pharmacological research

Breast cancer resistance protein (BCRP/ABCG2) and P-glycoprotein (P-gp/ABCB1) transport afatinib and restrict its oral availability and brain accumulation.

The EMBO journal

USP4 inhibits SMAD4 monoubiquitination and promotes activin and BMP signaling.

Cancer research

BRCA2 Hypomorphic Missense Variants Confer Moderate Risks of Breast Cancer.

Breast (Edinburgh, Scotland)

Feasibility of magnetic marker localisation for non-palpable breast cancer.

European urology

A Functional Genetic Screen Identifies the Phosphoinositide 3-kinase Pathway as a Determinant of Resistance to Fibroblast Growth Factor Receptor Inhibitors in FGFR Mutant Urothelial Cell Carcinoma.

Nature reviews. Clinical oncology

Drug therapy: Exploiting synthetic lethality to improve cancer therapy.

Therapeutic drug monitoring

Development and Validation of an LC-MS/MS Method for the Simultaneous Quantification of Abiraterone, Enzalutamide, and Their Major Metabolites in Human Plasma.

Journal of cancer survivorship : research and practice

Toward the optimal strategy for sustained weight loss in overweight cancer survivors: a systematic review of the literature.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Breast Cancer After Childhood, Adolescent, and Young Adult Cancer: It's Not Just About Chest Radiation.

European radiology

Trends and patterns of computed tomography scan use among children in The Netherlands: 1990-2012.

Abdominal radiology (New York)

Measuring the apparent diffusion coefficient in primary rectal tumors: is there a benefit in performing histogram analyses?

Nature communications

Systematic discovery of mutation-specific synthetic lethals by mining pan-cancer human primary tumor data.

BMC cancer

Fluorescent CXCR4 targeting peptide as alternative for antibody staining in Ewing sarcoma.

Cancer imaging : the official publication of the International Cancer Imaging Society

Additional value of ¹⁸F-FDG PET/CT response evaluation in axillary nodes during neoadjuvant therapy for triple-negative and HER2-positive breast cancer.

BMC public health

The role of Indonesian patients' health behaviors in delaying the diagnosis of nasopharyngeal carcinoma.

Ubiquitination and SUMOylation in Telomere Maintenance and Dysfunction

PloS one

Monitoring tumor response to neoadjuvant chemotherapy using MRI and 18F-FDG PET/CT in breast cancer subtypes.

British journal of cancer

Pretreatment serum uracil concentration as a predictor of severe and fatal fluoropyrimidine-associated toxicity.

Breast cancer research : BCR

An updated PREDICT breast cancer prognostication and treatment benefit prediction model with independent validation.

Trials

Efficacy, cost-utility and reach of an eHealth self-management application 'Oncokompas' that helps cancer survivors to obtain optimal supportive care: study protocol for a randomised controlled trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Ten-Year Progression-Free and Overall Survival in Patients With Unresectable or Metastatic GI Stromal Tumors: Long-Term Analysis of the European Organisation for Research and Treatment of Cancer, Italian Sarcoma Group, and Australasian Gastrointestinal Trials Group Intergroup Phase III Randomized Trial on Imatinib at Two Dose Levels.

Cell

Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression.

Health and quality of life outcomes

International evaluation of the psychometrics of health-related quality of life questionnaires for use among long-term survivors of testicular and prostate cancer.