Publications

Cold Spring Harbor symposia on quantitative biology

Genetic Dissection of Cancer Development, Therapy Response, and Resistance in Mouse Models of Breast Cancer.

07-11-2016

Cancer treatment reviews

Improving safety of fluoropyrimidine chemotherapy by individualizing treatment based on dihydropyrimidine dehydrogenase activity - Ready for clinical practice?

01-11-2016

Clinical pharmacokinetics

A Semi-Physiological Population Model to Quantify the Effect of Hematocrit on Everolimus Pharmacokinetics and Pharmacodynamics in Cancer Patients.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Health-related quality of life in the randomised KEYNOTE-002 study of pembrolizumab versus chemotherapy in patients with ipilimumab-refractory melanoma.

01-11-2016

Urologic oncology

Prostate cancer survivors with a passive role preference in treatment decision-making are less satisfied with information received: Results from the PROFILES registry.

01-11-2016

EMBO reports

Drugging the addict: non-oncogene addiction as a target for cancer therapy.

01-11-2016

Acta oncologica (Stockholm, Sweden)

Prospective Dutch colorectal cancer cohort: an infrastructure for long-term observational, prognostic, predictive and (randomized) intervention research.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

An MRI-based mid-ventilation approach for radiotherapy of the liver.

01-11-2016

International journal of radiation oncology, biology, physics

Risk of Symptomatic Stroke After Radiation Therapy for Childhood Cancer: A Long-Term Follow-Up Cohort Analysis.

01-11-2016

Clinical cancer research : an official journal of the American Association for Cancer Research

Loss of ARID1A Activates ANXA1, which Serves as a Predictive Biomarker for Trastuzumab Resistance.

01-11-2016

AJR. American journal of roentgenology

Diagnostic Accuracy of CT for Local Staging of Colon Cancer: A Systematic Review and Meta-Analysis.

01-11-2016

International journal of radiation oncology, biology, physics

Head and Neck Margin Reduction With Adaptive Radiation Therapy: Robustness of Treatment Plans Against Anatomy Changes.

01-11-2016

Journal of the National Cancer Institute

Mechanisms of Therapy Resistance in Patient-Derived Xenograft Models of BRCA1-Deficient Breast Cancer.

01-11-2016

Lasers in surgery and medicine

In vivo tumor identification of colorectal liver metastases with diffuse reflectance and fluorescence spectroscopy.

01-11-2016

European journal of cancer (Oxford, England : 1990)

The use of EORTC measures in daily clinical practice-A synopsis of a newly developed manual.

01-11-2016

European journal of cancer (Oxford, England : 1990)

Corrigendum to "2nd St. Gallen EORTC Gastrointestinal Cancer Conference: Consensus recommendations on controversial issues in the primary treatment of rectal cancer" [Eur J Cancer 63 (August 2016) 11-24].

01-11-2016

JAMA oncology

Genomics- and Transcriptomics-Based Patient Selection for Cancer Treatment With Immune Checkpoint Inhibitors: A Review.

01-11-2016

European journal of cell biology

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression.

01-11-2016

European urology

The Effect of Salvage Radiotherapy and its Timing on the Health-related Quality of Life of Prostate Cancer Patients.

01-11-2016

Cancer treatment reviews

Inventory of oral anticancer agents: Pharmaceutical formulation aspects with focus on the solid dispersion technique.

01-11-2016

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Consensus opinion on MRI simulation for external beam radiation treatment planning.

01-11-2016

Frontiers in oncology

The MRI-Linear Accelerator Consortium: Evidence-Based Clinical Introduction of an Innovation in Radiation Oncology Connecting Researchers, Methodology, Data Collection, Quality Assurance, and Technical Development.

30-10-2016

Methods in molecular biology (Clifton, N.J.)

pMHC Multiplexing Strategy to Detect High Numbers of T Cell Responses in Parallel.

28-10-2016

Epigenetics & chromatin

High-throughput assessment of context-dependent effects of chromatin proteins.

26-10-2016

Journal of pharmaceutical and biomedical analysis

Recent developments in the chromatographic bioanalysis of approved kinase inhibitor drugs in oncology.

25-10-2016

JAMA

Breast Cancer Risk After Ovarian Stimulation for In Vitro Fertilization-Reply.

25-10-2016

Oncotarget

Large variety in a panel of human colon cancer organoids in response to EZH2 inhibition.

25-10-2016

BMC systems biology

BCM: toolkit for Bayesian analysis of Computational Models using samplers.

21-10-2016

Breast cancer research : BCR

Prognostic value of automated KI67 scoring in breast cancer: a centralised evaluation of 8088 patients from 10 study groups.

18-10-2016

The Journal of experimental medicine

Preventing tumor escape by targeting a post-proteasomal trimming independent epitope.

17-10-2016

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Liquid chromatography-tandem mass spectrometric assay for therapeutic drug monitoring of the B-Raf inhibitor encorafenib, the EGFR inhibitors afatinib, erlotinib and gefitinib and the O-desmethyl metabolites of erlotinib and gefitinib in human plasma.

15-10-2016

Cancer research

The PARP Inhibitor AZD2461 Provides Insights into the Role of PARP3 Inhibition for Both Synthetic Lethality and Tolerability with Chemotherapy in Preclinical Models.

15-10-2016

Oncotarget

Identification of breast cancer cell subtypes sensitive to ATG4B inhibition.

11-10-2016

Cancer cell

Glycerophosphodiesterase GDE2 Promotes Neuroblastoma Differentiation through Glypican Release and Is a Marker of Clinical Outcome.

10-10-2016

Cancer cell

SOX2 Is the Determining Oncogenic Switch in Promoting Lung Squamous Cell Carcinoma from Different Cells of Origin.

10-10-2016

Journal of controlled release : official journal of the Controlled Release Society

Inherent formulation issues of kinase inhibitors.

10-10-2016

Nature

X-ray structures define human P2X(3) receptor gating cycle and antagonist action.

06-10-2016

Oncogene

Collagen-rich stroma in aggressive colon tumors induces mesenchymal gene expression and tumor cell invasion.

06-10-2016

American journal of human genetics

Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.

06-10-2016

Breast cancer research : BCR

Patient survival and tumor characteristics associated with CHEK2:p.I157T - findings from the Breast Cancer Association Consortium.

03-10-2016

Cancer

A randomized phase 2 study exploring the role of bevacizumab and a chemotherapy-free approach in HER2-positive metastatic breast cancer: The HAT study (BOOG 2008-2003), a Dutch Breast Cancer Research Group trial.

01-10-2016

Breast (Edinburgh, Scotland)

Don't forget the dentist: Dental care use and needs of women with breast cancer.

01-10-2016

Urologic oncology

Using the neoadjuvant chemotherapy paradigm to develop precision therapy for muscle-invasive bladder cancer.

01-10-2016

Cancer chemotherapy and pharmacology

Patients homozygous for DPYD c.1129-5923C>G/haplotype B3 have partial DPD deficiency and require a dose reduction when treated with fluoropyrimidines.

01-10-2016

The oncologist

Antidrug Antibody Formation in Oncology: Clinical Relevance and Challenges.

01-10-2016

Gastroenterology

Deletion of Polycomb Repressive Complex 2 From Mouse Intestine Causes Loss of Stem Cells.

01-10-2016

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Toward (Hybrid) Navigation of a Fluorescence Camera in an Open Surgery Setting.

01-10-2016

Minerva urologica e nefrologica = The Italian journal of urology and nephrology

Stapling for prostate pedicle management during robot-assisted radical prostatectomy.

01-10-2016

Acta diabetologica

Impact of cancer diagnosis and treatment on glycaemic control among individuals with colorectal cancer using glucose-lowering drugs.

01-10-2016

Assay and drug development technologies

HC StratoMineR: A Web-Based Tool for the Rapid Analysis of High-Content Datasets.

01-10-2016