Publications

Drug development and industrial pharmacy

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies.

01-04-2017

Familial cancer

Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.

01-04-2017

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Specific adverse events are associated with response to exemestane therapy in postmenopausal breast cancer patients: Results from the TEAMIIA study (BOOG2006-04).

01-04-2017

Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation

Impact of neurocognitive deficits on patient-proxy agreement regarding health-related quality of life in low-grade glioma patients.

01-04-2017

Therapeutic drug monitoring

Fast and Adequate Liquid Chromatography-Tandem Mass Spectrometric Determination of Z-endoxifen Serum Levels for Therapeutic Drug Monitoring.

01-04-2017

European journal of cancer (Oxford, England : 1990)

An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint^®).

01-04-2017

Nature reviews. Cancer

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

01-04-2017

European journal of cancer (Oxford, England : 1990)

Cost-effectiveness of capecitabine and bevacizumab maintenance treatment after first-line induction treatment in metastatic colorectal cancer.

01-04-2017

Annals of surgical oncology

Standard Clinical Protocol for Bidirectional Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Systemic Leucovorin, 5-Fluorouracil, and Heated Intraperitoneal Oxaliplatin in a Chloride-Containing Carrier Solution.

01-04-2017

FEBS open bio

The G2 checkpoint-a node-based molecular switch.

01-04-2017

The Lancet. Oncology

Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial.

01-04-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Effects of Budesonide on Cabazitaxel Pharmacokinetics and Cabazitaxel-Induced Diarrhea: A Randomized, Open-Label Multicenter Phase II Study.

01-04-2017

Diseases of the colon and rectum

MRI for Local Staging of Colon Cancer: Can MRI Become the Optimal Staging Modality for Patients With Colon Cancer?

01-04-2017

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Hybrid Surgical Guidance: Does Hardware Integration of γ- and Fluorescence Imaging Modalities Make Sense?

01-04-2017

Methods in molecular biology (Clifton, N.J.)

GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.

30-03-2017

Oncogene

Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora.

30-03-2017

BMC cancer

Design of a randomized controlled trial of physical training and cancer (Phys-Can) - the impact of exercise intensity on cancer related fatigue, quality of life and disease outcome.

27-03-2017

Cell

Rejuvenation by Therapeutic Elimination of Senescent Cells.

23-03-2017

Physics in medicine and biology

Directional sinogram interpolation for motion weighted 4D cone-beam CT reconstruction.

21-03-2017

PloS one

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae.

16-03-2017

Oncotarget

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer.

15-03-2017

Oncotarget

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.

14-03-2017

Journal of medicinal chemistry

Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.

09-03-2017

Breast cancer research : BCR

The method of detection of ductal carcinoma in situ has no therapeutic implications: results of a population-based cohort study.

09-03-2017

PloS one

Changes in brain activation in breast cancer patients depend on cognitive domain and treatment type.

08-03-2017

ESMO open

Career opportunities and benefits for young oncologists in the European Society for Medical Oncology (ESMO).

04-03-2017

Theranostics

Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.

04-03-2017

Molecular cell

An Interaction Landscape of Ubiquitin Signaling.

02-03-2017

Cancer cytopathology

Human epididymis protein 4 immunostaining of malignant ascites differentiates cancer of Müllerian origin from gastrointestinal cancer.

01-03-2017

Oral oncology

Salivary gland pleomorphic adenoma in the Netherlands: A nationwide observational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence.

01-03-2017

Medical physics

Multicenter validation of prostate tumor localization using multiparametric MRI and prior knowledge.

01-03-2017

European journal of cancer (Oxford, England : 1990)

Trastuzumab in combination with weekly paclitaxel and carboplatin as neo-adjuvant treatment for HER2-positive breast cancer: The TRAIN-study.

01-03-2017

Immunobiology

Expression and characterization of recombinant chicken mannose binding lectin.

01-03-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.

01-03-2017

European journal of cancer (Oxford, England : 1990)

Peripheral CD8 effector-memory type 1 T-cells correlate with outcome in ipilimumab-treated stage IV melanoma patients.

01-03-2017

Clinical pharmacokinetics

Development of a Pharmacokinetic Model to Describe the Complex Pharmacokinetics of Pazopanib in Cancer Patients.

01-03-2017

Clinical lung cancer

Predictors and Patterns of Regional Recurrence Following Lung SBRT: A Report From the Elekta Lung Research Group.

01-03-2017

Current opinion in supportive and palliative care

Cancer-related cognitive impairment and patients' ability to work: a current perspective.

01-03-2017

The Journal of pathology

Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice.

01-03-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

01-03-2017

Clinical pharmacokinetics

Imatinib Pharmacokinetics in a Large Observational Cohort of Gastrointestinal Stromal Tumour Patients.

01-03-2017

Surgical oncology

The diagnostic performance of ¹⁸F-FDG PET/CT, CT and MRI in the treatment evaluation of ablation therapy for colorectal liver metastases: A systematic review and meta-analysis.

01-03-2017

Psycho-oncology

The European organization for research and treatment of cancer - satisfaction with cancer care questionnaire: revision and extended application development.

01-03-2017

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

(Neo)adjuvant systemic therapy for melanoma.

01-03-2017

Endocrine-related cancer

A review of estrogen receptor/androgen receptor genomics in male breast cancer.

01-03-2017

Annals of oncology : official journal of the European Society for Medical Oncology

Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.

01-03-2017

Clinical cancer research : an official journal of the American Association for Cancer Research

BRCA1-Mutated Estrogen Receptor-Positive Breast Cancer Shows BRCAness, Suggesting Sensitivity to Drugs Targeting Homologous Recombination Deficiency.

01-03-2017

Gastroenterology

Real-Time Monitoring of Results During First Year of Dutch Colorectal Cancer Screening Program and Optimization by Altering Fecal Immunochemical Test Cut-Off Levels.

01-03-2017

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Recurrent oropharyngeal cancer after organ preserving treatment: pattern of failure and survival.

01-03-2017

Intravital

Intravital characterization of tumor cell migration in pancreatic cancer.

01-03-2017

Pharmaceutical development of an amorphous solid dispersion formulation of elacridar hydrochloride for proof-of-concept clinical studies.

Truncation of the MSH2 C-terminal 60 amino acids disrupts effective DNA mismatch repair and is causative for Lynch syndrome.

Specific adverse events are associated with response to exemestane therapy in postmenopausal breast cancer patients: Results from the TEAMIIA study (BOOG2006-04).

Impact of neurocognitive deficits on patient-proxy agreement regarding health-related quality of life in low-grade glioma patients.

Fast and Adequate Liquid Chromatography-Tandem Mass Spectrometric Determination of Z-endoxifen Serum Levels for Therapeutic Drug Monitoring.

An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint®).

Interrogating open issues in cancer precision medicine with patient-derived xenografts.

Cost-effectiveness of capecitabine and bevacizumab maintenance treatment after first-line induction treatment in metastatic colorectal cancer.

Standard Clinical Protocol for Bidirectional Hyperthermic Intraperitoneal Chemotherapy (HIPEC): Systemic Leucovorin, 5-Fluorouracil, and Heated Intraperitoneal Oxaliplatin in a Chloride-Containing Carrier Solution.

The G2 checkpoint-a node-based molecular switch.

Custirsen in combination with docetaxel and prednisone for patients with metastatic castration-resistant prostate cancer (SYNERGY trial): a phase 3, multicentre, open-label, randomised trial.

Effects of Budesonide on Cabazitaxel Pharmacokinetics and Cabazitaxel-Induced Diarrhea: A Randomized, Open-Label Multicenter Phase II Study.

MRI for Local Staging of Colon Cancer: Can MRI Become the Optimal Staging Modality for Patients With Colon Cancer?

Hybrid Surgical Guidance: Does Hardware Integration of γ- and Fluorescence Imaging Modalities Make Sense?

GRO-seq, A Tool for Identification of Transcripts Regulating Gene Expression.

Inhibition of Polo-like kinase 1 during the DNA damage response is mediated through loss of Aurora A recruitment by Bora.

Design of a randomized controlled trial of physical training and cancer (Phys-Can) - the impact of exercise intensity on cancer related fatigue, quality of life and disease outcome.

Rejuvenation by Therapeutic Elimination of Senescent Cells.

Directional sinogram interpolation for motion weighted 4D cone-beam CT reconstruction.

The effect of acetaminophen on ubiquitin homeostasis in Saccharomyces cerevisiae.

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer.

TP53-based interaction analysis identifies cis-eQTL variants for TP53BP2, FBXO28, and FAM53A that associate with survival and treatment outcome in breast cancer.

Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators.

The method of detection of ductal carcinoma in situ has no therapeutic implications: results of a population-based cohort study.

Changes in brain activation in breast cancer patients depend on cognitive domain and treatment type.

Career opportunities and benefits for young oncologists in the European Society for Medical Oncology (ESMO).

Hybrid Imaging Labels: Providing the Link Between Mass Spectrometry-Based Molecular Pathology and Theranostics.

An Interaction Landscape of Ubiquitin Signaling.

Human epididymis protein 4 immunostaining of malignant ascites differentiates cancer of Müllerian origin from gastrointestinal cancer.

Salivary gland pleomorphic adenoma in the Netherlands: A nationwide observational study of primary tumor incidence, malignant transformation, recurrence, and risk factors for recurrence.

Multicenter validation of prostate tumor localization using multiparametric MRI and prior knowledge.

Trastuzumab in combination with weekly paclitaxel and carboplatin as neo-adjuvant treatment for HER2-positive breast cancer: The TRAIN-study.

Expression and characterization of recombinant chicken mannose binding lectin.

Potential Targets' Analysis Reveals Dual PI3K/mTOR Pathway Inhibition as a Promising Therapeutic Strategy for Uterine Leiomyosarcomas-an ENITEC Group Initiative.

Peripheral CD8 effector-memory type 1 T-cells correlate with outcome in ipilimumab-treated stage IV melanoma patients.

Development of a Pharmacokinetic Model to Describe the Complex Pharmacokinetics of Pazopanib in Cancer Patients.

Predictors and Patterns of Regional Recurrence Following Lung SBRT: A Report From the Elekta Lung Research Group.

Cancer-related cognitive impairment and patients' ability to work: a current perspective.

Prophylactic window therapy with the clinical poly(ADP-ribose) polymerase inhibitor olaparib delays BRCA1-deficient mammary tumour formation in mice.

PI3K-mTOR Pathway Inhibition Exhibits Efficacy Against High-grade Glioma in Clinically Relevant Mouse Models.

Imatinib Pharmacokinetics in a Large Observational Cohort of Gastrointestinal Stromal Tumour Patients.

The diagnostic performance of 18F-FDG PET/CT, CT and MRI in the treatment evaluation of ablation therapy for colorectal liver metastases: A systematic review and meta-analysis.

The European organization for research and treatment of cancer - satisfaction with cancer care questionnaire: revision and extended application development.

(Neo)adjuvant systemic therapy for melanoma.

A review of estrogen receptor/androgen receptor genomics in male breast cancer.

Vemurafenib in metastatic melanoma patients with brain metastases: an open-label, single-arm, phase 2, multicentre study.

BRCA1-Mutated Estrogen Receptor-Positive Breast Cancer Shows BRCAness, Suggesting Sensitivity to Drugs Targeting Homologous Recombination Deficiency.

Real-Time Monitoring of Results During First Year of Dutch Colorectal Cancer Screening Program and Optimization by Altering Fecal Immunochemical Test Cut-Off Levels.

Recurrent oropharyngeal cancer after organ preserving treatment: pattern of failure and survival.

Intravital characterization of tumor cell migration in pancreatic cancer.

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An association study of established breast cancer reproductive and lifestyle risk factors with tumour subtype defined by the prognostic 70-gene expression signature (MammaPrint^®).

The diagnostic performance of ¹⁸F-FDG PET/CT, CT and MRI in the treatment evaluation of ablation therapy for colorectal liver metastases: A systematic review and meta-analysis.