Publications

Clinical cancer research : an official journal of the American Association for Cancer Research

plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis-Derived Variants in Liquid Biopsies from Patients with Solid Tumors.

01-05-2026

Nature communications

TrialMatchAI: an end-to-end AI-powered clinical trial recommendation system to streamline patient-to-trial matching.

25-03-2026

Annals of surgical oncology

Prognostic Value of Circulating Tumor DNA for Recurrence and Survival in Patients Undergoing Local Treatment for Initially Unresectable RAS/RAF Mutated Colorectal Cancer Liver Metastases.

01-02-2026

ESMO open

Added value of tumor-stroma ratio to postsurgery circulating tumor DNA and pTN stage in risk stratification of patients with stage III colon cancer treated with adjuvant chemotherapy.

01-01-2026

EBioMedicine

Combining cell-free DNA fragmentomes and total tumour volume improves prognostication and tumour response evaluation in patients with colorectal cancer liver metastases.

01-01-2026

The British journal of surgery

Circulating tumour DNA in patients with stage III colon cancer: multicentre prospective PROVENC3 study.

24-12-2025

Therapeutic advances in medical oncology

CtDNA-guided de-escalation of adjuvant chemotherapy in stage III colon cancer: early model-based evaluation of cost-effectiveness.

10-11-2025

Journal of experimental & clinical cancer research : CR

Fostering the implementation of liquid biopsy in clinical practice: meeting report 2024 of the European Liquid Biopsy Society (ELBS).

23-05-2025

NPJ precision oncology

Tumor break load quantitates structural variant-associated genomic instability with biological and clinical relevance across cancers.

14-05-2025

PharmacoEconomics

Towards Recommendations for Cost-Effectiveness Analysis of Predictive, Prognostic, and Serial Biomarker Tests in Oncology.

01-05-2025

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Staging peritoneal metastases in colorectal cancer: The correlation between MRI, surgical and histopathological peritoneal cancer index.

01-12-2024

Nature communications

Cancer treatment monitoring using cell-free DNA fragmentomes.

21-10-2024

Bioinformatics (Oxford, England)

CIBRA identifies genomic alterations with a system-wide impact on tumor biology.

01-09-2024

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

First-line palliative systemic therapy alternated with oxaliplatin-based pressurized intraperitoneal aerosol chemotherapy for unresectable colorectal peritoneal metastases: A single-arm phase II trial (CRC-PIPAC-II).

01-09-2024

Therapeutic advances in medical oncology

Early evaluation of the effectiveness and cost-effectiveness of ctDNA-guided selection for adjuvant chemotherapy in stage II colon cancer.

23-08-2024

Frontiers in genetics

Methylenetetrahydrofolate reductase polymorphic variants C677T and A1298C in rectal cancer in Slavic population: significance for cancer risk and response to chemoradiotherapy.

30-01-2024

Cancer research communications

Risk Prediction of Metachronous Colorectal Cancer from Molecular Features of Adenomas: A Nested Case-Control Study.

13-11-2023

Frontiers in genetics

Exploring novel genetic and hematological predictors of response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer.

18-09-2023

BMJ open

Towards Response ADAptive Radiotherapy for organ preservation for intermediate-risk rectal cancer (preRADAR): protocol of a phase I dose-escalation trial.

15-06-2023

The Journal of molecular diagnostics : JMD

A Micro-Costing Framework for Circulating Tumor DNA Testing in Dutch Clinical Practice.

01-01-2023

European journal of cancer (Oxford, England : 1990)

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

01-12-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

Cell genomics

A multi-platform reference for somatic structural variation detection.

08-06-2022

Cancers

Cell-Free Circulating (Tumor) DNA before Surgery as a Prognostic Factor in Non-Metastatic Colorectal Cancer: A Systematic Review.

29-04-2022

Communications biology

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.

08-04-2022

European journal of radiology

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

01-04-2022

JCO precision oncology

Reply to R. Pham et al.

01-03-2022

JCO clinical cancer informatics

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

01-02-2022

JCO precision oncology

KRAS A146 Mutations Are Associated With Distinct Clinical Behavior in Patients With Colorectal Liver Metastases.

26-11-2021

Nature communications

Detection and characterization of lung cancer using cell-free DNA fragmentomes.

20-08-2021

JAMA surgery

Perioperative Systemic Therapy vs Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy Alone for Resectable Colorectal Peritoneal Metastases: A Phase 2 Randomized Clinical Trial.

01-08-2021

EMBO reports

Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.

04-06-2021

Proteomics. Clinical applications

Lipopolysaccharide-regulated secretion of soluble and vesicle-based proteins from a panel of colorectal cancer cell lines.

01-05-2021

BMJ open

First-line palliative systemic therapy alternated with electrostatic pressurised intraperitoneal aerosol chemotherapy (oxaliplatin) for isolated unresectable colorectal peritoneal metastases: protocol of a multicentre, single-arm, phase II study (CRC-PIPAC-II).

30-03-2021

European journal of cancer (Oxford, England : 1990)

Quantitative analysis of CDX2 protein expression improves its clinical utility as a prognostic biomarker in stage II and III colon cancer.

01-02-2021

Oncoimmunology

Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.

13-10-2020

The European journal of health economics : HEPAC : health economics in prevention and care

Modeling Personalized Adjuvant TreaTment in EaRly stage coloN cancer (PATTERN).

01-09-2020

BMC cancer

Circulating tumor DNA guided adjuvant chemotherapy in stage II colon cancer (MEDOCC-CrEATE): study protocol for a trial within a cohort study.

20-08-2020

International journal of molecular sciences

Silencing Core Spliceosome Sm Gene Expression Induces a Cytotoxic Splicing Switch in the Proteasome Subunit Beta 3 mRNA in Non-Small Cell Lung Cancer Cells.

12-06-2020

Scientific reports

Performance of four platforms for KRAS mutation detection in plasma cell-free DNA: ddPCR, Idylla, COBAS z480 and BEAMing.

15-05-2020

International journal of cancer

Molecular characterization of colorectal adenomas reveals POFUT1 as a candidate driver of tumor progression.

01-04-2020

Nature communications

White blood cell and cell-free DNA analyses for detection of residual disease in gastric cancer.

27-01-2020

Molecular aspects of medicine

Circulating biomarkers for early detection and clinical management of colorectal cancer.

01-10-2019

BMJ open

Repetitive electrostatic pressurised intraperitoneal aerosol chemotherapy (ePIPAC) with oxaliplatin as a palliative monotherapy for isolated unresectable colorectal peritoneal metastases: protocol of a Dutch, multicentre, open-label, single-arm, phase II study (CRC-PIPAC).

27-07-2019

Nature

Genome-wide cell-free DNA fragmentation in patients with cancer.

01-06-2019

BMC cancer

Perioperative systemic therapy and cytoreductive surgery with HIPEC versus upfront cytoreductive surgery with HIPEC alone for isolated resectable colorectal peritoneal metastases: protocol of a multicentre, open-label, parallel-group, phase II-III, randomised, superiority study (CAIRO6).

25-04-2019

Cell

Widespread and Functional RNA Circularization in Localized Prostate Cancer.

07-02-2019

The Journal of pathology

Consensus molecular subtype classification of colorectal adenomas.

01-11-2018

Cancer prevention research (Philadelphia, Pa.)

Evaluation of Cancer-Associated DNA Copy Number Events in Colorectal (Advanced) Adenomas.

01-07-2018

Oncotarget

MACROD2 expression predicts response to 5-FU-based chemotherapy in stage III colon cancer.

29-06-2018