Banner Publications MH200828 N141

Publications

Results found: 252

Showing results: 151 - 200

Nat Med: Nature medicine

Chemotherapy response of spontaneous mammary tumors is independent of the adaptive immune system

06-03-2012
Drug Resist Updates: reviews and commentaries in antimicrobial and anticancer chemotherapy

A rapidly growing number of therapeutics targeting tumor cell-intrinsic and -extrinsic processes is under development for individualized treatment of cancer patients

01-03-2012
Mol Cell Proteomics: Molecular & cellular proteomics: MCP

Proteomics of mouse BRCA1-deficient mammary tumors identifies DNA repair proteins with potential diagnostic and prognostic value in human breast cancer

24-02-2012
Nature

Deleted in colorectal carcinoma suppresses metastasis in p53-deficient mammary tumours.

22-02-2012
Current opinion in genetics & development

Using genetically engineered mouse models to validate candidate cancer genes and test new therapeutic approaches.

01-02-2012
Cellular and molecular life sciences : CMLS

Genomic instability in breast and ovarian cancers: translation into clinical predictive biomarkers.

01-01-2012
Cancer cell

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

13-12-2011
Genome research

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

01-12-2011
Hum Mutat: Human mutation

ENIGMA--evidence-based network for the interpretation of germline mutant alleles: an international initiative to evaluate risk and clinical significance associated with sequence variation in BRCA1 and BRCA2 genes

03-11-2011
BioEssays : news and reviews in molecular, cellular and developmental biology

Rapid validation of cancer genes in chimeras derived from established genetically engineered mouse models.

01-09-2011
Gut

Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer

24-08-2011
Nucleic acids research

Computational identification of insertional mutagenesis targets for cancer gene discovery.

01-08-2011
J Clin Invest: The Journal of clinical investigation

Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance

11-07-2011
The Journal of pathology

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression.

01-05-2011
Disease models & mechanisms

Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice.

01-05-2011
The Journal of pathology

Development of metastatic HER2(+) breast cancer is independent of the adaptive immune system.

01-05-2011
Journal of mammary gland biology and neoplasia

Studying therapy response and resistance in mouse models for BRCA1-deficient breast cancer.

01-04-2011
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine

Potential value of color-coded dynamic breast-specific gamma-imaging; comparing (99m)Tc-(V)-DMSA, (99m)Tc-MIBI, and (99m)Tc-HDP in a mouse mammary tumor model.

01-12-2010
BMC cancer

BRCA1-mutated and basal-like breast cancers have similar aCGH profiles and a high incidence of protein truncating TP53 mutations.

30-11-2010
Nat Struct Mol Biol.: Nature structural & molecular biology

BRCA2 acts as a RAD51 loader to facilitate telomere replication and capping

14-11-2010
BMC research notes

KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data.

11-11-2010
Genome Biology

Somatic structural rearrangements in genetically engineered mouse mammary tumors

13-10-2010
Cell cycle (Georgetown, Tex.)

Tumor-initiating cells are not enriched in cisplatin-surviving BRCA1;p53-deficient mammary tumor cells in vivo.

15-09-2010
Nanotechnology

A self-assembled multimodal complex for combined pre- and intraoperative imaging of the sentinel lymph node.

03-09-2010
BMC cancer

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers.

24-08-2010
Trends Pharmacol Sci.: Trends in pharmacological sciences

Targeting homologous recombination repair defects in cancer

01-08-2010
Nature structural & molecular biology

53BP1 loss rescues BRCA1 deficiency and is associated with triple-negative and BRCA-mutated breast cancers.

01-06-2010
Nature cell biology

BRD7 is a candidate tumour suppressor gene required for p53 function.

01-04-2010
Cancer research

Sensitivity and acquired resistance of BRCA1;p53-deficient mouse mammary tumors to the topoisomerase I inhibitor topotecan.

15-02-2010
Cancer Research

Novel candidate cancer genes identified by a large-scale cross-species comparative oncogenomics approach

26-01-2010
Cancer research

Insertional mutagenesis in mice deficient for p15Ink4b, p16Ink4a, p21Cip1, and p27Kip1 reveals cancer gene interactions and correlations with tumor phenotypes.

15-01-2010
Oncogene

Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways.

07-01-2010
PLoS computational biology

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach.

01-01-2010
Clinical cancer research : an official journal of the American Association for Cancer Research

A high-throughput pharmaceutical screen identifies compounds with specific toxicity against BRCA2-deficient tumors.

01-01-2010
The Journal of pathology

A tissue reconstitution model to study cancer cell-intrinsic and -extrinsic factors in mammary tumourigenesis.

01-01-2010
Proc Natl Acad Sci U S A: Proceedings of the National Academy of Sciences of the United States of America

Error-prone translesion replication of damaged DNA suppresses skin carcinogenesis by controlling inflammatory hyperplasia

22-12-2009
Methods in molecular biology (Clifton, N.J.)

Studying drug resistance using genetically engineered mouse models for breast cancer.

02-12-2009
Biochimica et biophysica acta

Therapeutic options for triple-negative breast cancers with defective homologous recombination.

01-12-2009
British journal of cancer

Preclinical mouse models for BRCA1-associated breast cancer.

17-11-2009
Breast cancer research : BCR

BRCA1-deficient mammary tumor cells are dependent on EZH2 expression and sensitive to Polycomb Repressive Complex 2-inhibitor 3-deazaneplanocin A.

28-08-2009
Clinical cancer research: an official journal of the American Association for Cancer Research

CIP2A is associated with human breast cancer aggressivity

15-08-2009
Cancer research

Moderate increase in Mdr1a/1b expression causes in vivo resistance to doxorubicin in a mouse model for hereditary breast cancer.

15-08-2009
Breast cancer research: BRC

It's all in the details: methods in breast development and cancer

14-08-2009
Cancer Research

Fibroblast growth factor receptor 1-transformed mammary epithelial cells are dependent on RSK activity for growth and survival

01-08-2009
Nature protocols

A high-throughput splinkerette-PCR method for the isolation and sequencing of retroviral insertion sites.

17-06-2009
Current pharmaceutical design

Towards understanding the role of cancer-associated inflammation in chemoresistance.

13-06-2009
Cancer cell

Mammary tumorigenesis through LPA receptor signaling.

02-06-2009
Cancer research

High incidence of protein-truncating TP53 mutations in BRCA1-related breast cancer.

15-04-2009
J Pathol.: The journal of pathology

Conditional Pten knock-out mice: a model for metastatic phaeochromocytoma

01-03-2009
Breast cancer research : BCR

EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer.

23-12-2008

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