Banner Publications MH200828 N141

Publications

Results found: 252

Showing results: 201 - 250

Proceedings of the National Academy of Sciences of the United States of America

High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs.

04-11-2008
The EMBO journal

NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin

08-10-2008
Cell cycle (Georgetown, Tex.)

Mouse models for BRCA1 associated tumorigenesis: from fundamental insights to preclinical utility.

01-09-2008
Current biology : CB

Bmi1 regulates stem cells and proliferation and differentiation of committed cells in mammary epithelium.

22-07-2008
Clinical cancer research : an official journal of the American Association for Cancer Research

Selective inhibition of BRCA2-deficient mammary tumor cell growth by AZD2281 and cisplatin.

15-06-2008
Cell

Large-scale mutagenesis in p19(ARF)- and p53-deficient mice identifies cancer genes and their collaborative networks.

16-05-2008
Cell cycle (Georgetown, Tex.)

How do real tumors become resistant to cisplatin?

15-05-2008
Nucleic acids research

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data.

01-02-2008
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Modeling therapy resistance in genetically engineered mouse cancer models.

01-01-2008
Cell cycle (Georgetown, Tex.)

What makes tumors multidrug resistant?

15-11-2007
Physiol Genomics: Physiological genomics

Toxicity of ligand-dependent Cre recombinases and generation of a conditional Cre deleter mouse allowing mosaic recombination in peripheral tissues

19-09-2007
Journal of mammary gland biology and neoplasia

Modeling metastatic breast cancer in mice.

01-09-2007
Proceedings of the National Academy of Sciences of the United States of America

Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer.

17-07-2007
Proceedings of the National Academy of Sciences of the United States of America

Somatic loss of BRCA1 and p53 in mice induces mammary tumors with features of human BRCA1-mutated basal-like breast cancer.

17-07-2007
Nature genetics

MMTV insertional mutagenesis identifies genes, gene families and pathways involved in mammary cancer.

01-06-2007
Cancer research

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage

15-05-2007
Gastroenterology

Telomerase deletion limits progression of p53-mutant hepatocellular carcinoma with short telomeres in chronic liver disease

01-04-2007
Cell

Further evidence for BRCA1 communication with the inactive X chromosome

09-03-2007
Am J Pathol: The American journal of pathology

Aneuploidy arises at early stages of Apc-driven intestinal tumorigenesis and pinpoints conserved chromosomal loci of allelic imbalance between mouse and human

01-01-2007
Experimental cel research

Conditional inactivation of Brca1 in the mouse ovarian surface epithelium results in an increase in preneoplastic changes

01-01-2007
Cancer cell

Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis.

01-11-2006
Oncogene

Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.

25-09-2006
Molecular and cellular biology

Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development.

01-07-2006
FASEB journal: official publication of the Federation of American Societies for Experimental Biology

Macrophage retinoblastoma deficiency leads to enhanced atherosclerosis development in ApoE-deficient mice

01-05-2006
Nucleic acids research

Human and mouse oligonucleotide-based array CGH

16-12-2005
Cancer research

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development

15-09-2005
Genes & development

Frat is dispensable for canonical Wnt signaling in mammals.

15-02-2005
Cancer cell

Oncogene addiction: sometimes a temporary slavery.

01-12-2004
Oncogene

Fgf10 is an oncogene activated by MMTV insertional mutagenesis in mouse mammary tumors and overexpressed in a subset of human breast carcinomas.

12-08-2004
Nature genetics

Mutagenic insertion and chromosome engineering resource (MICER)

01-08-2004
Molecular and cellular biology

Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors.

01-07-2004
The Journal of biological chemistry

Characterization and functional analysis of the murine Frat2 gene.

25-06-2004
Genome research

A whole-genome mouse BAC microarray with 1-Mb resolution for analysis of DNA copy number changes by array comparative genomic hybridization

01-01-2004
Nature reviews. Cancer

Conditional mouse models of sporadic cancer.

01-04-2002
Cancer research

Noninvasive imaging of spontaneous retinoblastoma pathway-dependent tumors in mice.

15-03-2002
Nature genetics

Synergistic tumor suppressor activity of BRCA2 and p53 in a conditional mouse model for breast cancer.

01-12-2001
Proceedings of the National Academy of Sciences of the United States of America

Growth inhibition and DNA damage induced by Cre recombinase in mammalian cells.

31-07-2001
EMBO reports

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent.

01-04-2001
Experimental cell research

Mouse models for sporadic cancer.

10-03-2001
Cancer gene therapy

Lymphoid abnormalities in CD40 ligand transgenic mice suggest the need for tight regulation in gene therapy approaches to hyper immunoglobulin M (IgM) syndrome

01-10-2000
Genes & development

Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum.

15-04-2000
Mechanisms of development

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3.

01-11-1999
Oncogene

Overexpression of Frat1 in transgenic mice leads to glomerulosclerosis and nephrotic syndrome, and provides direct evidence for the involvement of Frat1 in lymphoma progression.

28-10-1999
The EMBO journal

Axin and Frat1 interact with dvl and GSK, bridging Dvl to GSK in Wnt-mediated regulation of LEF-1

02-08-1999
Cancer research

Identification and characterization of collaborating oncogenes in compound mutant mice.

01-04-1999
The EMBO journal

Activation of a novel proto-oncogene, Frat1, contributes to progression of mouse T-cell lymphomas.

03-02-1997
Journal of virology

Characterization of pal-1, a common proviral insertion site in murine leukemia virus-induced lymphomas of c-myc and Pim-1 transgenic mice.

01-01-1997
Biochimica et biophysica acta

Retroviral insertional mutagenesis as a strategy to identify cancer genes.

16-05-1996
Cold Spring Harbor symposia on quantitative biology

Mouse model systems to study multistep tumorigenesis.

01-01-1994
Plant molecular biology

Preparation of megabase-sized tomato DNA and separation of large restriction fragments by field inversion gel electrophoresis (FIGE)

01-03-1989

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