Banner Publications MH200828 N141

Publications

Results found: 252

Showing results: 101 - 150

Annals of oncology : official journal of the European Society for Medical Oncology

Inhibition of the spindle assembly checkpoint kinase TTK enhances the efficacy of docetaxel in a triple-negative breast cancer model.

01-10-2015
Oncogene

FOXA1 repression is associated with loss of BRCA1 and increased promoter methylation and chromatin silencing in breast cancer.

24-09-2015
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Extent of radiosensitization by the PARP inhibitor olaparib depends on its dose, the radiation dose and the integrity of the homologous recombination pathway of tumor cells.

01-09-2015
Pain

Morphine does not facilitate breast cancer progression in two preclinical mouse models for human invasive lobular and HER2⁺ breast cancer.

01-08-2015
Proceedings of the National Academy of Sciences of the United States of America

Selective resistance to the PARP inhibitor olaparib in a mouse model for BRCA1-deficient metaplastic breast cancer.

07-07-2015
Nature

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis.

18-06-2015
Nature

REV7 counteracts DNA double-strand break resection and affects PARP inhibition.

28-05-2015
International journal of cancer

Sorafenib synergizes with metformin in NSCLC through AMPK pathway activation.

15-03-2015
Genome biology

CopywriteR: DNA copy number detection from off-target sequence data.

27-02-2015
Cancer research

BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.

15-02-2015
The EMBO journal

BRCA1 and CtIP promote alternative non-homologous end-joining at uncapped telomeres.

03-02-2015
J Pathol.: The journal of pathology

Spontaneous bone metastases in a preclinical orthotopic model of invasive lobular carcinoma; the effect of pharmacological targeting TGFβ receptor I kinase

23-01-2015
J Proteome Res.: Journal of proteome research

The use of mass spectrometry imaging to predict treatment response of patient-derived xenograft models of triple-negative breast cancer

20-01-2015
Cell reports

Prolonged Ezh2 Depletion in Glioblastoma Causes a Robust Switch in Cell Fate Resulting in Tumor Progression.

20-01-2015
Cell death & disease

Suppression of BRCA1 sensitizes cells to proteasome inhibitors.

18-12-2014
Nucleic Acids Res.: Nucleic Acids research

INFRAFRONTIER--providing mutant mouse resources as research tools for the international scientific community

20-11-2014
Cell

Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways.

23-10-2014
Nature biotechnology

Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping.

01-10-2014
Proceedings of the National Academy of Sciences of the United States of America

Chromosome instability induced by Mps1 and p53 mutation generates aggressive lymphomas exhibiting aneuploidy-induced stress.

16-09-2014
Clinical cancer research : an official journal of the American Association for Cancer Research

Functional ex vivo assay to select homologous recombination-deficient breast tumors for PARP inhibitor treatment.

15-09-2014
Cancer discovery

Patient-derived xenograft models: an emerging platform for translational cancer research.

01-09-2014
PloS one

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases.

02-08-2014
Oncogene

Opportunities and hurdles in the treatment of BRCA1-related breast cancer.

17-07-2014
British journal of cancer

Mammary gland-specific ablation of focal adhesion kinase reduces the incidence of p53-mediated mammary tumour formation.

27-05-2014
Breast Cancer Research: BRC

Genomic patterns resembling BRCA1- and BRCA2-mutated breast cancers predict benefit of intensified carboplatin-based chemotherapy

15-05-2014
Clinical cancer research : an official journal of the American Association for Cancer Research

Molecular pathways: how can BRCA-mutated tumors become resistant to PARP inhibitors?

01-02-2014
EMBO molecular medicine

Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells.

01-02-2014
Cell death and differentiation

Epidermal Snail expression drives skin cancer initiation and progression through enhanced cytoprotection, epidermal stem/progenitor cell expansion and enhanced metastatic potential.

01-02-2014
Cancer discovery

A high-throughput functional complementation assay for classification of BRCA1 missense variants.

01-10-2013
Stem Cells (Dayton, Ohio)

Somatic loss of p53 leads to stem/progenitor cell amplification in both mammary epithelial compartments, basal and luminal

01-09-2013
Stem cells (Dayton, Ohio)

Polycomb group gene Ezh2 regulates mammary gland morphogenesis and maintains the luminal progenitor pool.

01-09-2013
J Exp Med.: The journal of experimental medicine

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

15-07-2013
Scientific reports

Defined lipid analogues induce transient channels to facilitate drug-membrane traversal and circumvent cancer therapy resistance.

07-06-2013
Cancer Research

Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling

03-06-2013
Nat Commun.: Nature communications

ARF triggers senescence in Brca2-deficient cells by altering the spectrum of p53 transcriptional targets

01-06-2013
PloS one

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

22-05-2013
Proc Natl Acad Sci U S A: Proceedings of the National Academy of Siences of the United States of America

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

08-05-2013
Molecular oncology

Genetically engineered mouse models of PI3K signaling in breast cancer.

01-04-2013
The Journal of pathology

An α-E-catenin (CTNNA1) mutation in hereditary diffuse gastric cancer.

01-03-2013
Mol Cell Proteomics: Molecular & cellular proteomics: MCP

Proteomics of genetically engineered mouse mammary tumors identifies fatty acid metabolism members as potential predictive markers for cisplatin resistance

08-02-2013
PLoS One

Use of a single hybrid imaging agent for integration of target validation with in vivo and ex vivo imaging of mouse tumor lesions resembling human DCIS

11-01-2013
Cancer discovery

Loss of 53BP1 causes PARP inhibitor resistance in Brca1-mutated mouse mammary tumors.

01-01-2013
Cancer research

A preclinical mouse model of invasive lobular breast cancer metastasis.

01-01-2013
Genes Dev.: Genes & development

BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny

27-12-2012
The Journal of pathology

Developmental stage-specific contribution of LGR5(+) cells to basal and luminal epithelial lineages in the postnatal mammary gland.

01-11-2012
PloS one

EZN-2208 (PEG-SN38) overcomes ABCG2-mediated topotecan resistance in BRCA1-deficient mouse mammary tumors.

03-10-2012
Nature reviews. Cancer

The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.

01-09-2012
Cancer prevention research (Philadelphia, Pa.)

Lack of ABCG2 shortens latency of BRCA1-deficient mammary tumors and this is not affected by genistein or resveratrol.

01-08-2012
Cancer discovery

Tracking evolution of BRCA1-associated breast cancer.

01-06-2012
Cancer research

Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.

01-05-2012

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