Publications

Medical image analysis

DeepSMILE: Contrastive self-supervised pre-training benefits MSI and HRD classification directly from H&E whole-slide images in colorectal and breast cancer.

01-07-2022

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Image-based analysis of skeletal muscle mass predicts cisplatin dose-limiting toxicity in patients with locally advanced head and neck cancer.

01-07-2022

Cancer chemotherapy and pharmacology

Development of a population pharmacokinetic/pharmacodynamic model for various oral paclitaxel formulations co-administered with ritonavir and thrombospondin-1 based on data from early phase clinical studies.

01-07-2022

Breast cancer research and treatment

Limiting systemic endocrine overtreatment in postmenopausal breast cancer patients with an ultralow classification of the 70-gene signature.

01-07-2022

British journal of cancer

Low probability of disease cure in advanced ovarian carcinomas before the PARP inhibitor era.

01-07-2022

Journal for immunotherapy of cancer

Efficacy of anti-PD-1 and ipilimumab alone or in combination in acral melanoma.

01-07-2022

Journal for immunotherapy of cancer

Dendritic cell-mediated cross presentation of tumor-derived peptides is biased against plasma membrane proteins.

01-07-2022

Clinical pharmacology and therapeutics

Dihydropyrimidine Dehydrogenase Phenotyping Using Pretreatment Uracil: A Note of Caution Based on a Large Prospective Clinical Study.

01-07-2022

European urology

Robot-assisted Prostate-specific Membrane Antigen-radioguided Salvage Surgery in Recurrent Prostate Cancer Using a DROP-IN Gamma Probe: The First Prospective Feasibility Study.

01-07-2022

International journal of computer assisted radiology and surgery

A hybrid registration method using the mandibular bone surface for electromagnetic navigation in mandibular surgery.

01-07-2022

Retinal cases & brief reports

BILATERAL SEROUS RETINAL DETACHMENT AND UVEITIS ASSOCIATED WITH PEMBROLIZUMAB TREATMENT IN METASTATIC MELANOMA.

01-07-2022

Cancers

Specialist versus Primary Care Prostate Cancer Follow-Up: A Process Evaluation of a Randomized Controlled Trial.

28-06-2022

Nature communications

Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

27-06-2022

Frontiers in oncology

Longitudinal Correlations Between Intravoxel Incoherent Motion (IVIM) and Dynamic Contrast-Enhanced (DCE) MRI During Radiotherapy in Prostate Cancer Patients.

25-06-2022

Cancers

Epithelial-to-Mesenchymal Transition Drives Invasiveness of Breast Cancer Brain Metastases.

25-06-2022

Nature communications

DNA damage-induced transcription stress triggers the genome-wide degradation of promoter-bound Pol II.

24-06-2022

Nederlands tijdschrift voor geneeskunde

[Communicating personalised health information].

22-06-2022

Cell reports. Medicine

RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells.

21-06-2022

Cell reports. Medicine

TIL classified to memory state are correlated with response to immune checkpoint blockade.

21-06-2022

Radiation oncology (London, England)

Effect of intrafraction adaptation on PTV margins for MRI guided online adaptive radiotherapy for rectal cancer.

21-06-2022

Frontiers in genetics

Editorial: Advancement in Gene Set Analysis: Gaining Insight From High-Throughput Data.

18-06-2022

Breast cancer research : BCR

Combined inhibition of EZH2 and ATM is synthetic lethal in BRCA1-deficient breast cancer.

17-06-2022

STAR protocols

Protocol for live-cell imaging during Tumor Treating Fields treatment with Inovitro Live.

17-06-2022

Current oncology (Toronto, Ont.)

A Narrative Review on the Collection and Use of Electronic Patient-Reported Outcomes in Cancer Survivorship Care with Emphasis on Symptom Monitoring.

17-06-2022

Cancers

Unraveling Desmoid-Type Fibromatosis-Specific Health-Related Quality of Life: Who Is at Risk for Poor Outcomes.

16-06-2022

Cancers

Triplet Chemotherapy with Cisplatin versus Oxaliplatin in the CRITICS Trial: Treatment Compliance, Toxicity, Outcomes and Quality of Life in Patients with Resectable Gastric Cancer.

15-06-2022

Stem cell reports

Characterization of the epidermal-dermal junction in hiPSC-derived skin organoids.

14-06-2022

Journal of the National Cancer Institute

Measuring Clinical, Biological, and Behavioral Variables to Elucidate Trajectories of Patient-Reported Outcomes: The PROFILES Registry.

13-06-2022

Frontiers in pharmacology

Editorial: Therapeutic Drug Monitoring (TDM): A Useful Tool for Pediatric Pharmacology Applied to Routine Clinical Practice.

11-06-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prospective Cardiovascular Surveillance of Immune Checkpoint Inhibitor-Based Combination Therapy in Patients With Advanced Renal Cell Cancer: Data From the Phase III JAVELIN Renal 101 Trial.

10-06-2022

Scientific reports

HideRNAs protect against CRISPR-Cas9 re-cutting after successful single base-pair gene editing.

10-06-2022

Cell genomics

A multi-platform reference for somatic structural variation detection.

08-06-2022

NPJ breast cancer

Allelic expression imbalance of PIK3CA mutations is frequent in breast cancer and prognostically significant.

08-06-2022

Cellular and molecular life sciences : CMLS

SETD2: from chromatin modifier to multipronged regulator of the genome and beyond.

06-06-2022

Journal of pharmaceutical and biomedical analysis

A highly sensitive bioanalytical method for the quantification of vinblastine, vincristine, vinorelbine and 4-O-deacetylvinorelbine in human plasma using LC-MS/MS.

05-06-2022

Sarcoma

Targeting the FAK-Src Complex in Desmoplastic Small Round Cell Tumors, Ewing Sarcoma, and Rhabdomyosarcoma.

04-06-2022

Journal of cell science

Molecular determinants of αVβ5 localization in flat clathrin lattices - role of αVβ5 in cell adhesion and proliferation.

01-06-2022

Annals of surgical oncology

Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

01-06-2022

Nature structural & molecular biology

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.

01-06-2022

Urologic oncology

Minimally invasive evaluation of the clinically negative inguinal node in penile cancer: Dynamic sentinel node biopsy.

01-06-2022

European urology oncology

Surgical Safety of Deferred Cytoreductive Nephrectomy Following Pretreatment with Immune Checkpoint Inhibitor-based Dual Combination Therapy.

01-06-2022

Drugs - real world outcomes

Being Transparent About Brilliant Failures: An Attempt to Use Real-World Data in a Disease Model for Patients with Castration-Resistant Prostate Cancer.

01-06-2022

ESMO open

Systemic treatment of advanced clear cell sarcoma: results from a retrospective international series from the World Sarcoma Network.

01-06-2022

Nature reviews. Clinical oncology

COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety.

01-06-2022

The Journal of pathology

The earliest events in BRAF-mutant colorectal cancer: exome sequencing of sessile serrated lesions with a tiny focus dysplasia or cancer reveals recurring mutations in two distinct progression pathways.

01-06-2022

ESMO open

Setting the international research agenda for sarcoma together with patients and carers: first results of the Sarcoma Patient EuroNet (SPAEN) priority setting partnership.

01-06-2022

JACC. CardioOncology

Physical Activity and Cardiac Function in Long-Term Breast Cancer Survivors: A Cross-Sectional Study.

01-06-2022

Oncogene

Functional RECAP (REpair CAPacity) assay identifies homologous recombination deficiency undetected by DNA-based BRCAness tests.

01-06-2022

British journal of haematology

Persistent symptoms of fatigue, neuropathy and role-functioning impairment among indolent non-Hodgkin lymphoma survivors: A longitudinal PROFILES registry study.

01-06-2022

Expert opinion on investigational drugs

Progress and pitfalls in the use of immunotherapy for patients with triple negative breast cancer.

01-06-2022