Publications

Cancers

Homologous Recombination Deficiency and Cyclin E1 Amplification Are Correlated with Immune Cell Infiltration and Survival in High-Grade Serous Ovarian Cancer.

02-12-2022

Theranostics

Current use and future potential of (physiologically based) pharmacokinetic modelling of radiopharmaceuticals: a review.

02-12-2022

Molecular cancer therapeutics

NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition.

02-12-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.

01-12-2022

Melanoma research

Long-term survival of patients with advanced melanoma treated with BRAF-MEK inhibitors.

01-12-2022

European journal of cancer (Oxford, England : 1990)

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

01-12-2022

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc

Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer.

01-12-2022

Data in brief

Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis.

01-12-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Dose response modelling of secretory cell loss in salivary glands using PSMA PET.

01-12-2022

Journal of medical genetics

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence.

01-12-2022

Nature reviews. Cancer

Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

01-12-2022

Archives of physical medicine and rehabilitation

Construct Validity of the Steep Ramp Test for Assessing Cardiorespiratory Fitness in Patients With Breast Cancer and the Effect of Chemotherapy-Related Symptom Burden.

01-12-2022

Critical reviews in oncology/hematology

Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe.

01-12-2022

ESMO open

Sex differences in patients with gastrointestinal stromal tumours: do they exist and does it affect survival?

01-12-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Quality of early prostate cancer follow-up care from the patients' perspective.

01-12-2022

Journal of medical genetics

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.

01-12-2022

ESMO open

Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics.

01-12-2022

Nature reviews. Cancer

Tumour avatars to model patients' responses to immunotherapy.

01-12-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer.

01-12-2022

Gynecologic and obstetric investigation

Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research.

01-12-2022

International journal of cancer

Survival after neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer.

01-12-2022

Breast cancer research and treatment

Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors.

01-12-2022

Neuro-oncology

Factors associated with health-related quality of life (HRQoL) deterioration in glioma patients during the progression-free survival period.

01-12-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

01-12-2022

Journal of structural biology

Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain.

01-12-2022

Journal of neuro-oncology

Neurocognitive functioning after Gamma Knife and LINAC stereotactic radiosurgery in patients with brain metastases.

01-12-2022

JAMA oncology

Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma.

01-12-2022

European radiology

Quantification and reduction of cross-vendor variation in multicenter DWI MR imaging: results of the Cancer Core Europe imaging task force.

01-12-2022

Epigenetics

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

01-12-2022

Clinical pharmacokinetics

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology.

01-12-2022

NeuroImage

A unified model for reconstruction and R₂^* mapping of accelerated 7T data using the quantitative recurrent inference machine.

01-12-2022

International journal of cancer

Reply to: Comments on "Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial".

01-12-2022

Nature communications

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.

30-11-2022

eLife

Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations.

29-11-2022

Frontiers in pharmacology

SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin.

29-11-2022

Sensors (Basel, Switzerland)

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms.

28-11-2022

Frontiers in genetics

DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro.

26-11-2022

Cancers

Patterns of Hearing Loss in Irradiated Survivors of Head and Neck Rhabdomyosarcoma.

23-11-2022

Cell reports

DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.

22-11-2022

Breast cancer research : BCR

Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.

22-11-2022

Nature communications

Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

21-11-2022

Cancers

Systemic Therapy in Advanced Nodular Melanoma versus Superficial Spreading Melanoma: A Nation-Wide Study of the Dutch Melanoma Treatment Registry.

19-11-2022

Biomolecules

E-Cadherin Expression Distinguishes Mouse from Human Hematopoiesis in the Basophil and Erythroid Lineages.

17-11-2022

Cell reports. Medicine

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

15-11-2022

International journal of cancer

Reply to: Comments on "Neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer".

15-11-2022

World journal of gastrointestinal oncology

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

15-11-2022

Cell reports. Medicine

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.

15-11-2022

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.

15-11-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

14-11-2022

Cancers

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

13-11-2022

Homologous Recombination Deficiency and Cyclin E1 Amplification Are Correlated with Immune Cell Infiltration and Survival in High-Grade Serous Ovarian Cancer.

Current use and future potential of (physiologically based) pharmacokinetic modelling of radiopharmaceuticals: a review.

NOTCH Signaling Limits the Response of Low-Grade Serous Ovarian Cancers to MEK Inhibition.

Overestimation of the effect of (fos)aprepitant on intravenous dexamethasone pharmacokinetics requires adaptation of the guidelines for children with chemotherapy-induced nausea and vomiting.

Long-term survival of patients with advanced melanoma treated with BRAF-MEK inhibitors.

Tumour break load is a biologically relevant feature of genomic instability with prognostic value in colorectal cancer.

Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer.

Dataset of a retrospective multicenter cohort study on characteristics of immune checkpoint inhibitor-induced encephalitis and comparison with HSV-1 and anti-LGI1 encephalitis.

Dose response modelling of secretory cell loss in salivary glands using PSMA PET.

Enhancing the BOADICEA cancer risk prediction model to incorporate new data on RAD51C, RAD51D, BARD1 updates to tumour pathology and cancer incidence.

Learning to distinguish progressive and non-progressive ductal carcinoma in situ.

Construct Validity of the Steep Ramp Test for Assessing Cardiorespiratory Fitness in Patients With Breast Cancer and the Effect of Chemotherapy-Related Symptom Burden.

Cancer-related cognitive impairment in non-CNS cancer patients: Targeted review and future action plans in Europe.

Sex differences in patients with gastrointestinal stromal tumours: do they exist and does it affect survival?

Quality of early prostate cancer follow-up care from the patients' perspective.

Prospective validation of the BOADICEA multifactorial breast cancer risk prediction model in a large prospective cohort study.

Complete genomic characterization in patients with cancer of unknown primary origin in routine diagnostics.

Tumour avatars to model patients' responses to immunotherapy.

Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer.

Establishment of the Dutch Nationwide, Interdisciplinary Infrastructure and Biobank for Fundamental and Translational Ovarian Cancer Research: Archipelago of Ovarian Cancer Research.

Survival after neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer.

Adjuvant aromatase inhibitor therapy and early markers for cardiovascular disease in breast cancer survivors.

Factors associated with health-related quality of life (HRQoL) deterioration in glioma patients during the progression-free survival period.

Management of toxicities from immunotherapy: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up.

Crystal structure of the phospholipase A and acyltransferase 4 (PLAAT4) catalytic domain.

Neurocognitive functioning after Gamma Knife and LINAC stereotactic radiosurgery in patients with brain metastases.

Association of Immune-Related Adverse Event Management With Survival in Patients With Advanced Melanoma.

Quantification and reduction of cross-vendor variation in multicenter DWI MR imaging: results of the Cancer Core Europe imaging task force.

Evaluation of methylated DCR1 as a biomarker for response to adjuvant irinotecan-based therapy in stage III colon cancer: cancer and leukaemia Group B 89803 (Alliance).

Pharmacokinetics and Pharmacodynamics of PARP Inhibitors in Oncology.

A unified model for reconstruction and R2* mapping of accelerated 7T data using the quantitative recurrent inference machine.

Reply to: Comments on "Effect of HIPEC according to HRD/BRCAwt genomic profile in stage III ovarian cancer: Results from the phase III OVHIPEC trial".

Extensive androgen receptor enhancer heterogeneity in primary prostate cancers underlies transcriptional diversity and metastatic potential.

Mother cells control daughter cell proliferation in intestinal organoids to minimize proliferation fluctuations.

SLC7A8 coding for LAT2 is associated with early disease progression in osteosarcoma and transports doxorubicin.

Electronic Nose Sensor Drift Affects Diagnostic Reliability and Accuracy of Disease-Specific Algorithms.

DOT1L inhibition does not modify the sensitivity of cutaneous T cell lymphoma to pan-HDAC inhibitors in vitro.

Patterns of Hearing Loss in Irradiated Survivors of Head and Neck Rhabdomyosarcoma.

DOT1L regulates lipid biosynthesis and inflammatory responses in macrophages and promotes atherosclerotic plaque stability.

Correction: PredictCBC-2.0: a contralateral breast cancer risk prediction model developed and validated in ~ 200,000 patients.

Author Correction: Combinatorial immunotherapies overcome MYC-driven immune evasion in triple negative breast cancer.

Systemic Therapy in Advanced Nodular Melanoma versus Superficial Spreading Melanoma: A Nation-Wide Study of the Dutch Melanoma Treatment Registry.

E-Cadherin Expression Distinguishes Mouse from Human Hematopoiesis in the Basophil and Erythroid Lineages.

Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer.

Reply to: Comments on "Neoadjuvant/induction combination immunotherapy vs combination platinum-based chemotherapy for locally advanced (Stage III) urothelial cancer".

Missed colorectal cancers in a fecal immunochemical test-based screening program: Molecular profiling of interval carcinomas.

Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis.

Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.

PD-1T TILs as a Predictive Biomarker for Clinical Benefit to PD-1 Blockade in Patients with Advanced NSCLC.

Features on Endoscopy and MRI after Treatment with Contact X-ray Brachytherapy for Rectal Cancer: Explorative Results.

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A unified model for reconstruction and R₂^* mapping of accelerated 7T data using the quantitative recurrent inference machine.