Publications

Nature

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

10-08-2022

Immunity

The lung fibroblast as "soil fertilizer" in breast cancer metastasis.

09-08-2022

Nature communications

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.

05-08-2022

BMC cancer

Neoadjuvant nivolumab + T-VEC combination therapy for resectable early stage or metastatic (IIIB-IVM1a) melanoma with injectable disease: study protocol of the NIVEC trial.

04-08-2022

Cancers

External Quality Assessment 2.0: The Importance of a Standardized Implementation of TILs for Daily and Trial Practices.

02-08-2022

Nature communications

Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation.

02-08-2022

Therapeutic drug monitoring

Everolimus Concentration in Saliva to Predict Stomatitis: A Feasibility Study in Patients with Cancer.

01-08-2022

Cancer

First-line chemotherapy in advanced intra-abdominal well-differentiated/dedifferentiated liposarcoma: An EORTC Soft Tissue and Bone Sarcoma Group retrospective analysis.

01-08-2022

Neuro-oncology practice

Do neurocognitive impairments explain the differences between brain tumor patients and their proxies when assessing the patient's IADL?

01-08-2022

Expert review of clinical immunology

Bradford Hill and breast implant illness: no evidence for causal association with breast implants.

01-08-2022

Nature

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

01-08-2022

Critical reviews in oncology/hematology

Challenges in breast cancer genetic testing. A call for novel forms of multidisciplinary care and long-term evaluation.

01-08-2022

Patient education and counseling

Communication, perception, and use of personalized side-effect risks in prostate cancer treatment-decision making: An observational and interview study.

01-08-2022

Endocrine connections

Health-related quality of life following FDG-PET/CT for cytological indeterminate thyroid nodules.

01-08-2022

The Journal of cell biology

PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.

01-08-2022

Urology

Surgical and Functional Outcomes of Bladder Neck Incision for Primary Vesico-Urethral Anastomosis Stricture after Robot-assisted Radical Prostatectomy are Influenced by the Presence of Pre- or Postoperative Radiotherapy.

01-08-2022

Nature

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

01-08-2022

European journal of cancer (Oxford, England : 1990)

Trastuzumab and pertuzumab combination therapy for advanced pre-treated HER2 exon 20-mutated non-small cell lung cancer.

01-08-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.

01-08-2022

BMJ open

Budget impact analysis of providing hospital inpatient care at home virtually, starting with two specific surgical patient groups.

01-08-2022

Abdominal radiology (New York)

Identifying high-risk colon cancer on CT an a radiomics signature improve radiologist's performance for T staging?

01-08-2022

Clinica chimica acta; international journal of clinical chemistry

Diagnostic performance of early increase in S100B or LDH as outcome predictor for non-responsiveness to anti-PD-1 monotherapy in advanced melanoma.

01-08-2022

Annals of surgical oncology

Correction to: Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

01-08-2022

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

ABCB1 restricts brain accumulation of the novel RORγ agonist cintirorgon, while OATP1A/1B and CYP3A limit its oral availability.

01-08-2022

Clinical and translational science

Longitudinal nonlinear mixed effects modeling of EGFR mutations in ctDNA as predictor of disease progression in treatment of EGFR-mutant non-small cell lung cancer.

01-08-2022

Oncogene

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

01-08-2022

ESMO open

Short- and long-term impact of cancer on employment and financial outcomes of adolescents and young adults (AYAs): a large population-based case-control registry study in the Netherlands.

01-08-2022

Clinical pharmacology and therapeutics

Presence of Five Chemotherapeutic Drugs in Breast Milk as a Guide for the Safe Use of Chemotherapy During Breastfeeding: Results From a Case Series.

01-08-2022

European urology

Final Results of Neoadjuvant Atezolizumab in Cisplatin-ineligible Patients with Muscle-invasive Urothelial Cancer of the Bladder.

01-08-2022

Human reproduction (Oxford, England)

Fertility preservation for women with breast cancer: a multicentre randomized controlled trial on various ovarian stimulation protocols.

30-07-2022

Current oncology (Toronto, Ont.)

Recruiting Adolescent and Young Adult Cancer Survivors for Patient-Reported Outcome Research: Experiences and Sample Characteristics of the SURVAYA Study.

29-07-2022

Science advances

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.

29-07-2022

Trials

Design of a multinational randomized controlled trial to assess the effects of structured and individualized exercise in patients with metastatic breast cancer on fatigue and quality of life: the EFFECT study.

29-07-2022

Frontiers in neuroscience

Multi-Coil MRI Reconstruction Challenge-Assessing Brain MRI Reconstruction Models and Their Generalizability to Varying Coil Configurations.

26-07-2022

PloS one

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

26-07-2022

Methods in molecular biology (Clifton, N.J.)

Acute Protein Depletion Strategies to Functionally Dissect the 3D Genome.

23-07-2022

Nucleic acids research

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

22-07-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy.

20-07-2022

Scientific reports

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

16-07-2022

Cancer

Psychosocial consequences of surviving cancer diagnosed and treated in childhood versus in adolescence/young adulthood: A call for clearer delineation between groups.

15-07-2022

Science translational medicine

NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity.

13-07-2022

Pharmaceuticals (Basel, Switzerland)

Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs.

13-07-2022

Cancers

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.

11-07-2022

Diagnostics (Basel, Switzerland)

Exploiting the Dixon Method for a Robust Breast and Fibro-Glandular Tissue Segmentation in Breast MRI.

11-07-2022

Research involvement and engagement

A qualitative study on the involvement of adolescents and young adults (AYAs) with cancer during multiple research phases: "plan, structure, and discuss".

08-07-2022

Molecular cell

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.

07-07-2022

Cancer discovery

Can Drug Repurposing Accelerate Precision Oncology?

06-07-2022

Genes

Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Specific Dose of Temozolomide/Veliparib.

04-07-2022

PloS one

The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability.

02-07-2022

Frontiers in medicine

A Comparison of Post-marketing Measures Imposed by Regulatory Agencies to Confirm the Tissue-Agnostic Approach.

02-07-2022

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

The lung fibroblast as "soil fertilizer" in breast cancer metastasis.

Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.

Neoadjuvant nivolumab + T-VEC combination therapy for resectable early stage or metastatic (IIIB-IVM1a) melanoma with injectable disease: study protocol of the NIVEC trial.

External Quality Assessment 2.0: The Importance of a Standardized Implementation of TILs for Daily and Trial Practices.

Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation.

Everolimus Concentration in Saliva to Predict Stomatitis: A Feasibility Study in Patients with Cancer.

First-line chemotherapy in advanced intra-abdominal well-differentiated/dedifferentiated liposarcoma: An EORTC Soft Tissue and Bone Sarcoma Group retrospective analysis.

Do neurocognitive impairments explain the differences between brain tumor patients and their proxies when assessing the patient's IADL?

Bradford Hill and breast implant illness: no evidence for causal association with breast implants.

Author Correction: Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.

Challenges in breast cancer genetic testing. A call for novel forms of multidisciplinary care and long-term evaluation.

Communication, perception, and use of personalized side-effect risks in prostate cancer treatment-decision making: An observational and interview study.

Health-related quality of life following FDG-PET/CT for cytological indeterminate thyroid nodules.

PEAK1 Y635 phosphorylation regulates cell migration through association with Tensin3 and integrins.

Surgical and Functional Outcomes of Bladder Neck Incision for Primary Vesico-Urethral Anastomosis Stricture after Robot-assisted Radical Prostatectomy are Influenced by the Presence of Pre- or Postoperative Radiotherapy.

Truncated FGFR2 is a clinically actionable oncogene in multiple cancers.

Trastuzumab and pertuzumab combination therapy for advanced pre-treated HER2 exon 20-mutated non-small cell lung cancer.

Current and future diagnostic and treatment strategies for patients with invasive lobular breast cancer.

Budget impact analysis of providing hospital inpatient care at home virtually, starting with two specific surgical patient groups.

Identifying high-risk colon cancer on CT an a radiomics signature improve radiologist's performance for T staging?

Diagnostic performance of early increase in S100B or LDH as outcome predictor for non-responsiveness to anti-PD-1 monotherapy in advanced melanoma.

Correction to: Neoadjuvant Systemic Therapy (NAST) in Patients with Melanoma: Surgical Considerations by the International Neoadjuvant Melanoma Consortium (INMC).

ABCB1 restricts brain accumulation of the novel RORγ agonist cintirorgon, while OATP1A/1B and CYP3A limit its oral availability.

Longitudinal nonlinear mixed effects modeling of EGFR mutations in ctDNA as predictor of disease progression in treatment of EGFR-mutant non-small cell lung cancer.

Suppression of heparan sulfation re-sensitizes YAP1-driven melanoma to MAPK pathway inhibitors.

Short- and long-term impact of cancer on employment and financial outcomes of adolescents and young adults (AYAs): a large population-based case-control registry study in the Netherlands.

Presence of Five Chemotherapeutic Drugs in Breast Milk as a Guide for the Safe Use of Chemotherapy During Breastfeeding: Results From a Case Series.

Final Results of Neoadjuvant Atezolizumab in Cisplatin-ineligible Patients with Muscle-invasive Urothelial Cancer of the Bladder.

Fertility preservation for women with breast cancer: a multicentre randomized controlled trial on various ovarian stimulation protocols.

Recruiting Adolescent and Young Adult Cancer Survivors for Patient-Reported Outcome Research: Experiences and Sample Characteristics of the SURVAYA Study.

Chaperoning of the histone octamer by the acidic domain of DNA repair factor APLF.

Design of a multinational randomized controlled trial to assess the effects of structured and individualized exercise in patients with metastatic breast cancer on fatigue and quality of life: the EFFECT study.

Multi-Coil MRI Reconstruction Challenge-Assessing Brain MRI Reconstruction Models and Their Generalizability to Varying Coil Configurations.

Molecular characterization of gastric adenocarcinoma diagnosed in patients previously treated for Hodgkin lymphoma or testicular cancer.

Acute Protein Depletion Strategies to Functionally Dissect the 3D Genome.

Division of labor within the DNA damage tolerance system reveals non-epistatic and clinically actionable targets for precision cancer medicine.

Prognostic Value of Stromal Tumor-Infiltrating Lymphocytes in Young, Node-Negative, Triple-Negative Breast Cancer Patients Who Did Not Receive (neo)Adjuvant Systemic Therapy.

High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.

Psychosocial consequences of surviving cancer diagnosed and treated in childhood versus in adolescence/young adulthood: A call for clearer delineation between groups.

NK cells with tissue-resident traits shape response to immunotherapy by inducing adaptive antitumor immunity.

Predictiveness of the Human-CYP3A4-Transgenic Mouse Model (Cyp3aXAV) for Human Drug Exposure of CYP3A4-Metabolized Drugs.

Uncovering the Contribution of Moderate-Penetrance Susceptibility Genes to Breast Cancer by Whole-Exome Sequencing and Targeted Enrichment Sequencing of Candidate Genes in Women of European Ancestry.

Exploiting the Dixon Method for a Robust Breast and Fibro-Glandular Tissue Segmentation in Breast MRI.

A qualitative study on the involvement of adolescents and young adults (AYAs) with cancer during multiple research phases: "plan, structure, and discuss".

Systematic analysis of intrinsic enhancer-promoter compatibility in the mouse genome.

Can Drug Repurposing Accelerate Precision Oncology?

Tooth Formation as Experimental Model to Study Chemotherapy on Tissue Development: Effect of a Specific Dose of Temozolomide/Veliparib.

The impact of monosomies, trisomies and segmental aneuploidies on chromosomal stability.

A Comparison of Post-marketing Measures Imposed by Regulatory Agencies to Confirm the Tissue-Agnostic Approach.

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