Publications

Familial cancer

First international workshop of the ATM and cancer risk group (4-5 December 2019).

01-04-2022

Radiology

Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.

01-04-2022

Nature medicine

Delivering precision oncology to patients with cancer.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

01-04-2022

Virchows Archiv : an international journal of pathology

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: A multicentre observational cohort study (eQuiPe).

01-04-2022

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

01-04-2022

European journal of radiology

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

01-04-2022

Clinical genitourinary cancer

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

01-04-2022

Molecular cancer therapeutics

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

01-04-2022

Pharmacological research

ABCB1 limits brain exposure of the KRAS^G12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Male breast cancer after childhood cancer: Systematic review and analyses in the PanCareSurFup cohort.

01-04-2022

European journal of nuclear medicine and molecular imaging

The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection.

01-04-2022

Breast care (Basel, Switzerland)

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

01-04-2022

European journal of cancer (Oxford, England : 1990)

The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC.

01-04-2022

Medicine and science in sports and exercise

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer.

01-04-2022

Key Publication

Pharmacological research

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.

01-04-2022

Clinical pharmacokinetics

Correction to: Unbound Plasma, Total Plasma and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-04-2022

Cancer discovery

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.

01-04-2022

Magma (New York, N.Y.)

Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses.

01-04-2022

Nature biotechnology

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

01-04-2022

Nature

Nonlinear control of transcription through enhancer-promoter interactions.

01-04-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

01-04-2022

Pharmaceutical research

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.

01-04-2022

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Neoadjuvant Immunotherapy: Leveraging the Immune System to Treat Early-Stage Disease.

01-04-2022

Palliative medicine

Sexual health and closeness in couples coping with advanced cancer: Results of a multicenter observational study (eQuiPe).

01-04-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.

01-04-2022

Clinical breast cancer

Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?

01-04-2022

European urology

Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.

01-04-2022

Drug metabolism and disposition: the biological fate of chemicals

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

01-04-2022

JAMA surgery

Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.

01-04-2022

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Radiofrequency versus microwave ablation for intraoperative treatment of colorectal liver metastases.

01-04-2022

Journal of imaging

Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery.

31-03-2022

Cancers

Cell-Free DNA at Diagnosis for Stage IV Non-Small Cell Lung Cancer: Costs, Time to Diagnosis and Clinical Relevance.

31-03-2022

BMC medical research methodology

Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer.

27-03-2022

Frontiers in pharmacology

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites.

22-03-2022

Oncoimmunology

QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment.

22-03-2022

Nederlands tijdschrift voor geneeskunde

[Silicone breast implants: the importance of nuanced reporting].

21-03-2022

Oncology research and treatment

Sociodemographic, Clinical, Lifestyle, and Psychological Correlates of Peripheral Neuropathy among 2- to 12-Year Colorectal Cancer Survivors.

21-03-2022

STAR protocols

Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids.

18-03-2022

Methods in molecular biology (Clifton, N.J.)

Time-Domain Fluorescence Lifetime Imaging of cAMP Levels with EPAC-Based FRET Sensors.

15-03-2022

Aesthetic surgery journal

Silicone Particle Migration: A Misleading Report.

15-03-2022

JMIR cancer

Comparing Survivors of Cancer in Population-Based Samples With Those in Online Cancer Communities: Cross-sectional Questionnaire Study.

08-03-2022

Journal of the National Cancer Institute

Impact of Blinding on Patient-Reported Outcome Differences Between Treatment Arms in Cancer Randomized Controlled Trials.

08-03-2022

EJNMMI research

Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model.

07-03-2022

Physics in medicine and biology

Reducing 4DCBCT imaging dose and time: exploring the limits of adaptive acquisition and motion compensated reconstruction.

07-03-2022

BMC nursing

Remote continuous monitoring with wireless wearable sensors in clinical practice, nurses perspectives on factors affecting implementation: a qualitative study.

07-03-2022

Journal of patient-reported outcomes

Visualization formats of patient-reported outcome measures in clinical practice: a systematic review about preferences and interpretation accuracy.

03-03-2022

Current oncology reports

Early Therapeutic Interventions for Newly Diagnosed Glioblastoma: Rationale and Review of the Literature.

01-03-2022

Urologic oncology

Prognostic markers in invasive bladder cancer: FGFR3 mutation status versus P53 and KI-67 expression: a multi-center, multi-laboratory analysis in 1058 radical cystectomy patients.

01-03-2022

First international workshop of the ATM and cancer risk group (4-5 December 2019).

Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.

Delivering precision oncology to patients with cancer.

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: A multicentre observational cohort study (eQuiPe).

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.

Male breast cancer after childhood cancer: Systematic review and analyses in the PanCareSurFup cohort.

The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection.

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC.

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer.

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.

Correction to: Unbound Plasma, Total Plasma and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.

Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses.

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

Nonlinear control of transcription through enhancer-promoter interactions.

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.

Neoadjuvant Immunotherapy: Leveraging the Immune System to Treat Early-Stage Disease.

Sexual health and closeness in couples coping with advanced cancer: Results of a multicenter observational study (eQuiPe).

Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.

Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?

Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.

Radiofrequency versus microwave ablation for intraoperative treatment of colorectal liver metastases.

Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery.

Cell-Free DNA at Diagnosis for Stage IV Non-Small Cell Lung Cancer: Costs, Time to Diagnosis and Clinical Relevance.

Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer.

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites.

QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment.

[Silicone breast implants: the importance of nuanced reporting].

Sociodemographic, Clinical, Lifestyle, and Psychological Correlates of Peripheral Neuropathy among 2- to 12-Year Colorectal Cancer Survivors.

Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids.

Time-Domain Fluorescence Lifetime Imaging of cAMP Levels with EPAC-Based FRET Sensors.

Silicone Particle Migration: A Misleading Report.

Comparing Survivors of Cancer in Population-Based Samples With Those in Online Cancer Communities: Cross-sectional Questionnaire Study.

Impact of Blinding on Patient-Reported Outcome Differences Between Treatment Arms in Cancer Randomized Controlled Trials.

Feasibility of fluorescence imaging at microdosing using a hybrid PSMA tracer during robot-assisted radical prostatectomy in a large animal model.

Reducing 4DCBCT imaging dose and time: exploring the limits of adaptive acquisition and motion compensated reconstruction.

Remote continuous monitoring with wireless wearable sensors in clinical practice, nurses perspectives on factors affecting implementation: a qualitative study.

Visualization formats of patient-reported outcome measures in clinical practice: a systematic review about preferences and interpretation accuracy.

Early Therapeutic Interventions for Newly Diagnosed Glioblastoma: Rationale and Review of the Literature.

Prognostic markers in invasive bladder cancer: FGFR3 mutation status versus P53 and KI-67 expression: a multi-center, multi-laboratory analysis in 1058 radical cystectomy patients.

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ABCB1 limits brain exposure of the KRAS^G12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.