Publications

Communications biology

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.

08-04-2022

BMC cancer

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

08-04-2022

Nature communications

Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial.

06-04-2022

Cancers

Health-Related Quality of Life and Side Effects in Gastrointestinal Stromal Tumor (GIST) Patients Treated with Tyrosine Kinase Inhibitors: A Systematic Review of the Literature.

05-04-2022

Cell reports

FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer.

05-04-2022

Journal of clinical medicine

T_1ρ for Radiotherapy Treatment Response Monitoring in Rectal Cancer Patients: A Pilot Study.

02-04-2022

Laboratory investigation; a journal of technical methods and pathology

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target.

01-04-2022

Journal of cancer survivorship : research and practice

Self-perceived cognitive functioning and quality of life among cancer survivors: results from the PROFILES registry.

01-04-2022

Familial cancer

First international workshop of the ATM and cancer risk group (4-5 December 2019).

01-04-2022

Radiology

Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.

01-04-2022

Nature medicine

Delivering precision oncology to patients with cancer.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

01-04-2022

Virchows Archiv : an international journal of pathology

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: A multicentre observational cohort study (eQuiPe).

01-04-2022

British journal of cancer

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

01-04-2022

European journal of radiology

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

01-04-2022

Clinical genitourinary cancer

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

01-04-2022

Molecular cancer therapeutics

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

01-04-2022

Pharmacological research

ABCB1 limits brain exposure of the KRAS^G12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.

01-04-2022

European journal of cancer (Oxford, England : 1990)

Male breast cancer after childhood cancer: Systematic review and analyses in the PanCareSurFup cohort.

01-04-2022

European journal of nuclear medicine and molecular imaging

The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection.

01-04-2022

Breast care (Basel, Switzerland)

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

01-04-2022

European journal of cancer (Oxford, England : 1990)

The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC.

01-04-2022

Medicine and science in sports and exercise

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer.

01-04-2022

Key Publication

Pharmacological research

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.

01-04-2022

Clinical pharmacokinetics

Correction to: Unbound Plasma, Total Plasma and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

01-04-2022

Cancer discovery

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.

01-04-2022

Magma (New York, N.Y.)

Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses.

01-04-2022

Nature biotechnology

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

01-04-2022

Nature

Nonlinear control of transcription through enhancer-promoter interactions.

01-04-2022

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

01-04-2022

Pharmaceutical research

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.

01-04-2022

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

Neoadjuvant Immunotherapy: Leveraging the Immune System to Treat Early-Stage Disease.

01-04-2022

Palliative medicine

Sexual health and closeness in couples coping with advanced cancer: Results of a multicenter observational study (eQuiPe).

01-04-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.

01-04-2022

Clinical breast cancer

Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?

01-04-2022

European urology

Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.

01-04-2022

Drug metabolism and disposition: the biological fate of chemicals

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

01-04-2022

JAMA surgery

Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.

01-04-2022

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Radiofrequency versus microwave ablation for intraoperative treatment of colorectal liver metastases.

01-04-2022

Journal of imaging

Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery.

31-03-2022

Cancers

Cell-Free DNA at Diagnosis for Stage IV Non-Small Cell Lung Cancer: Costs, Time to Diagnosis and Clinical Relevance.

31-03-2022

BMC medical research methodology

Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer.

27-03-2022

Frontiers in pharmacology

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites.

22-03-2022

Oncoimmunology

QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment.

22-03-2022

Nederlands tijdschrift voor geneeskunde

[Silicone breast implants: the importance of nuanced reporting].

21-03-2022

Oncology research and treatment

Sociodemographic, Clinical, Lifestyle, and Psychological Correlates of Peripheral Neuropathy among 2- to 12-Year Colorectal Cancer Survivors.

21-03-2022

STAR protocols

Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids.

18-03-2022

Methods in molecular biology (Clifton, N.J.)

Time-Domain Fluorescence Lifetime Imaging of cAMP Levels with EPAC-Based FRET Sensors.

15-03-2022

Aesthetic surgery journal

Silicone Particle Migration: A Misleading Report.

15-03-2022

CRISPRs in the human genome are differentially expressed between malignant and normal adjacent to tumor tissue.

KCNQ1 and lymphovascular invasion are key features in a prognostic classifier for stage II and III colon cancer.

Predictive biomarkers for survival benefit with ramucirumab in urothelial cancer in the RANGE trial.

Health-Related Quality of Life and Side Effects in Gastrointestinal Stromal Tumor (GIST) Patients Treated with Tyrosine Kinase Inhibitors: A Systematic Review of the Literature.

FER regulates endosomal recycling and is a predictor for adjuvant taxane benefit in breast cancer.

T1ρ for Radiotherapy Treatment Response Monitoring in Rectal Cancer Patients: A Pilot Study.

A murine mesenchymal stem cell model for initiating events in osteosarcomagenesis points to CDK4/CDK6 inhibition as a therapeutic target.

Self-perceived cognitive functioning and quality of life among cancer survivors: results from the PROFILES registry.

First international workshop of the ATM and cancer risk group (4-5 December 2019).

Prediction of Upstaging in Ductal Carcinoma in Situ Based on Mammographic Radiomic Features.

Delivering precision oncology to patients with cancer.

Prognostic and predictive value of β-blockers in the EORTC 1325/KEYNOTE-054 phase III trial of pembrolizumab versus placebo in resected high-risk stage III melanoma.

MCM3 is a novel proliferation marker associated with longer survival for patients with tubo-ovarian high-grade serous carcinoma.

Quality of life and quality of care as experienced by patients with advanced cancer and their relatives: A multicentre observational cohort study (eQuiPe).

Molecular pathways in post-colonoscopy versus detected colorectal cancers: results from a nested case-control study.

Diagnostic performance of MRI for staging peritoneal metastases in patients with colorectal cancer after neoadjuvant chemotherapy.

A Serendipitous Preoperative Trial of Combined Ipilimumab Plus Nivolumab for Localized Prostate Cancer.

Functional Genomic Identification of Predictors of Sensitivity and Mechanisms of Resistance to Multivalent Second-Generation TRAIL-R2 Agonists.

ABCB1 limits brain exposure of the KRASG12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.

Male breast cancer after childhood cancer: Systematic review and analyses in the PanCareSurFup cohort.

The impact of drainage pathways on the detection of nodal metastases in prostate cancer: a phase II randomized comparison of intratumoral vs intraprostatic tracer injection for sentinel node detection.

Risk-Adjusted Cancer Screening and Prevention (RiskAP): Complementing Screening for Early Disease Detection by a Learning Screening Based on Risk Factors.

The role of perioperative chemotherapy in primary high-grade extremity soft tissue sarcoma: a risk-stratified analysis using PERSARC.

Physical Fitness and Chemotherapy Tolerance in Patients with Early-Stage Breast Cancer.

ABCB1 and ABCG2 limit brain penetration and, together with CYP3A4, total plasma exposure of abemaciclib and its active metabolites.

Correction to: Unbound Plasma, Total Plasma and Whole-Blood Tacrolimus Pharmacokinetics Early After Thoracic Organ Transplantation.

Plasticity of Extrachromosomal and Intrachromosomal BRAF Amplifications in Overcoming Targeted Therapy Dosage Challenges.

Eye-specific quantitative dynamic contrast-enhanced MRI analysis for patients with intraocular masses.

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

Nonlinear control of transcription through enhancer-promoter interactions.

Clinical Models to Define Response and Survival With Anti-PD-1 Antibodies Alone or Combined With Ipilimumab in Metastatic Melanoma.

Ritonavir-Boosted Exposure of Kinase Inhibitors: an Open Label, Cross-over Pharmacokinetic Proof-of-Concept Trial with Erlotinib.

Neoadjuvant Immunotherapy: Leveraging the Immune System to Treat Early-Stage Disease.

Sexual health and closeness in couples coping with advanced cancer: Results of a multicenter observational study (eQuiPe).

Patients with Rare Cancers in the Drug Rediscovery Protocol (DRUP) Benefit from Genomics-Guided Treatment.

Endocrine Therapy With or Without CDK4/6 Inhibitors in Women With Hormone-receptor Positive Breast Cancer: What do we Know About the Effects on Cognition?

Comprehensive Molecular Characterization Reveals Genomic and Transcriptomic Subtypes of Metastatic Urothelial Carcinoma.

Metabolic Disposition of Lurbinectedin, a Potent Selective Inhibitor of Active Transcription of Protein-Coding Genes, in Nonclinical Species and Patients.

Representativeness of the Index Lymph Node for Total Nodal Basin in Pathologic Response Assessment After Neoadjuvant Checkpoint Inhibitor Therapy in Patients With Stage III Melanoma.

Radiofrequency versus microwave ablation for intraoperative treatment of colorectal liver metastases.

Imaging PPG for In Vivo Human Tissue Perfusion Assessment during Surgery.

Cell-Free DNA at Diagnosis for Stage IV Non-Small Cell Lung Cancer: Costs, Time to Diagnosis and Clinical Relevance.

Developing a dynamic simulation model to support the nationwide implementation of whole genome sequencing in lung cancer.

Drug Transporters ABCB1 (P-gp) and OATP, but not Drug-Metabolizing Enzyme CYP3A4, Affect the Pharmacokinetics of the Psychoactive Alkaloid Ibogaine and its Metabolites.

QPCTL regulates macrophage and monocyte abundance and inflammatory signatures in the tumor microenvironment.

[Silicone breast implants: the importance of nuanced reporting].

Sociodemographic, Clinical, Lifestyle, and Psychological Correlates of Peripheral Neuropathy among 2- to 12-Year Colorectal Cancer Survivors.

Functional genetic dropout screens and in vivo validation of candidate therapeutic targets using mouse mammary tumoroids.

Time-Domain Fluorescence Lifetime Imaging of cAMP Levels with EPAC-Based FRET Sensors.

Silicone Particle Migration: A Misleading Report.

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T_1ρ for Radiotherapy Treatment Response Monitoring in Rectal Cancer Patients: A Pilot Study.

ABCB1 limits brain exposure of the KRAS^G12C inhibitor sotorasib, whereas ABCB1, CYP3A, and possibly OATP1a/1b restrict its oral availability.