Publications

Clinical pharmacokinetics

Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients.

01-11-2021

Physics in medicine and biology

Probabilistic target definition and planning in patients with prostate cancer.

28-10-2021

Journal of medicinal chemistry

Imaging Autotaxin In Vivo with ¹⁸F-Labeled Positron Emission Tomography Ligands.

28-10-2021

Cancers

Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions.

27-10-2021

Pharmaceuticals (Basel, Switzerland)

P-Glycoprotein (ABCB1/MDR1) and BCRP (ABCG2) Limit Brain Accumulation and Cytochrome P450-3A (CYP3A) Restricts Oral Exposure of the RET Inhibitor Selpercatinib (RETEVMO).

27-10-2021

Science translational medicine

Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancers.

27-10-2021

Proceedings of the National Academy of Sciences of the United States of America

Differential effects of PD-1 and CTLA-4 blockade on the melanoma-reactive CD8 T cell response.

26-10-2021

Journal of pharmaceutical and biomedical analysis

Quantification of anti-SARS-CoV-2 antibodies in human serum with LC-QTOF-MS.

25-10-2021

JMIR cancer

Exploring Cancer Survivor Needs and Preferences for Communicating Personalized Cancer Statistics From Registry Data: Qualitative Multimethod Study.

25-10-2021

The British journal of surgery

Prevalence of nodal involvement in rectal cancer after chemoradiotherapy.

23-10-2021

Pharmaceutics

ABCB1 and ABCG2 Control Brain Accumulation and Intestinal Disposition of the Novel ROS1/TRK/ALK Inhibitor Repotrectinib, While OATP1A/1B, ABCG2, and CYP3A Limit Its Oral Availability.

21-10-2021

Physics in medicine and biology

Deformation trajectory prediction using a neural network trained on finite element data-application to library of CTVs creation for cervical cancer.

21-10-2021

NPJ breast cancer

IHC-based Ki67 as response biomarker to tamoxifen in breast cancer window trials enrolling premenopausal women.

20-10-2021

Scientific reports

Dynamic FRET-FLIM based screening of signal transduction pathways.

20-10-2021

Frontiers in oncology

MR-Linac Radiotherapy - The Beam Angle Selection Problem.

19-10-2021

The EMBO journal

RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis.

18-10-2021

Genome medicine

Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer.

18-10-2021

International journal of cancer

Toxicity of pemetrexed during renal impairment explained-Implications for safe treatment.

15-10-2021

BMC public health

Supporting participation in paid work of cancer survivors and their partners in the Netherlands: protocol of the SusTained Employability in cancer Patients and their partnerS (STEPS) multi-centre randomized controlled trial and cohort study.

12-10-2021

Journal of chromatography. A

A generic sample preparation method for the multiplex analysis of seven therapeutic monoclonal antibodies in human plasma or serum with liquid chromatography-tandem mass spectrometry.

11-10-2021

Cancers

Hospital Variation in Cancer Treatments and Survival OutComes of Advanced Melanoma Patients: Nationwide Quality Assurance in The Netherlands.

11-10-2021

Journal of clinical medicine

The Prolonged Diagnostic Pathway of Young Adults (Aged 25-39) with Cancer in the United Kingdom: Results from the Young Adult Cancer Patient Journey Study.

11-10-2021

Cancers

Value of Assessing Peripheral Vascularization with Micro-Flow Imaging, Resistive Index and Absent Hilum Sign as Predictor for Malignancy in Lymph Nodes in Head and Neck Squamous Cell Carcinoma.

10-10-2021

Scientific reports

Germline variants and breast cancer survival in patients with distant metastases at primary breast cancer diagnosis.

05-10-2021

JMIR cancer

Characteristics of Participants and Nonparticipants in a Blended Internet-Based Physical Activity Trial for Breast and Prostate Cancer Survivors: Cross-sectional Study.

05-10-2021

Immuno-oncology technology

The (re)discovery of tumor-intrinsic determinants of immune sensitivity by functional genetic screens.

01-10-2021

Medical physics

Automatic breast lesion detection in ultrafast DCE-MRI using deep learning.

01-10-2021

Breast cancer research and treatment

Fatigue and resting-state functional brain networks in breast cancer patients treated with chemotherapy.

01-10-2021

Nature reviews. Gastroenterology & hepatology

Exploring liver cancer biology through functional genetic screens.

01-10-2021

Current opinion in cell biology

Intravital microscopy to illuminate cell state plasticity during metastasis.

01-10-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Diagnostic Value, Oncologic Outcomes, and Safety Profile of Image-Guided Surgery Technologies During Robot-Assisted Lymph Node Dissection with Sentinel Node Biopsy for Prostate Cancer.

01-10-2021

Drug and alcohol dependence

The suitability of oral diacetylmorphine in treatment-refractory patients with heroin dependence: A scoping review.

01-10-2021

Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Technologic (R)Evolution Leads to Detection of More Sentinel Nodes in Patients with Melanoma in the Head and Neck Region.

01-10-2021

Seminars in immunology

Impact of cancer cell-intrinsic features on neutrophil behavior.

01-10-2021

Molecular cancer research : MCR

Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen.

01-10-2021

Human gene therapy

Multimodular Optimization of Chemically Regulated T Cell Switches Demonstrates Flexible and Interchangeable Nature of Immune Cell Signaling Domains.

01-10-2021

Brain and behavior

Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses.

01-10-2021

Molecular oncology

The Porto European Cancer Research Summit 2021.

01-10-2021

The FEBS journal

Conserved residues Glu37 and Trp229 play an essential role in protein folding of β-lactamase.

01-10-2021

Breast cancer research and treatment

Improved risk estimation of locoregional recurrence, secondary contralateral tumors and distant metastases in early breast cancer: the INFLUENCE 2.0 model.

01-10-2021

Cellular and molecular life sciences : CMLS

Signals for antigen-independent differentiation of memory CD8⁺ T cells.

01-10-2021

Clinica chimica acta; international journal of clinical chemistry

Retrospective analysis of serum testosterone levels by LC-MS/MS in chemically castrated prostate cancer patients: Biological variation and analytical performance specifications.

01-10-2021

Pharmacological research

ABCB1 and ABCG2, but not CYP3A4 limit oral availability and brain accumulation of the RET inhibitor pralsetinib.

01-10-2021

Molecular cancer research : MCR

The Prognostic Potential of Human Prostate Cancer-Associated Macrophage Subtypes as Revealed by Single-Cell Transcriptomics.

01-10-2021

The British journal of radiology

Descriptive analysis of MRI functional changes occurring during reduced dose radiotherapy for myxoid liposarcomas.

01-10-2021

Preventive medicine

Impact of the suspension and restart of the Dutch breast cancer screening program on breast cancer incidence and stage during the COVID-19 pandemic.

01-10-2021

PloS one

Proteomic analysis identifies novel binding partners of BAP1.

01-10-2021

ESMO open

Priorities and preferences of advanced soft tissue sarcoma patients starting palliative chemotherapy: baseline results from the HOLISTIC study.

01-10-2021

European journal of cancer (Oxford, England : 1990)

Sex-differences in symptoms and functioning in >5000 cancer survivors: Results from the PROFILES registry.

01-10-2021

British journal of cancer

Mendelian randomisation study of smoking exposure in relation to breast cancer risk.

01-10-2021