Publications

Frontiers in genetics

Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair.

18-02-2022

Cancers

Physical Activity Is Associated with Improved Overall Survival among Patients with Metastatic Colorectal Cancer.

16-02-2022

Nederlands tijdschrift voor geneeskunde

[Clinical efficiency research with expensive drugs: doing more with less investment].

15-02-2022

Clinical cancer research : an official journal of the American Association for Cancer Research

Association of Neutrophil-to-Lymphocyte Ratio with Efficacy of First-Line Avelumab plus Axitinib vs. Sunitinib in Patients with Advanced Renal Cell Carcinoma Enrolled in the Phase 3 JAVELIN Renal 101 Trial.

15-02-2022

Trials

Combining Hepatic Percutaneous Perfusion with Ipilimumab plus Nivolumab in advanced uveal melanoma (CHOPIN): study protocol for a phase Ib/randomized phase II trial.

13-02-2022

Frontiers in immunology

Molecular, Immunological, and Clinical Features Associated With Lymphoid Neogenesis in Muscle Invasive Bladder Cancer.

12-02-2022

Nat Rev Neurol.

Cognitive adverse effects of chemotherapy and immunotherapy: are interventions within reach?

09-02-2022

Key Publication

Cell genomics

A large-scale organoid-based screening platform to advance drug repurposing in pancreatic cancer.

09-02-2022

Nature communications

A Mediator-cohesin axis controls heterochromatin domain formation.

08-02-2022

eLife

Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.

08-02-2022

Biomedical physics & engineering express

Image quality of dual-energy cone-beam CT with total nuclear variation regularization.

04-02-2022

Endocrine-related cancer

Pregnancy-associated breast cancer: the influence of gestational age.

04-02-2022

EMBO reports

Unexpected gene activation following CRISPR-Cas9-mediated genome editing.

03-02-2022

Methods in molecular biology (Clifton, N.J.)

Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.

02-02-2022

Methods in molecular biology (Clifton, N.J.)

Epi-Decoder: Decoding the Local Proteome of a Genomic Locus by Massive Parallel Chromatin Immunoprecipitation Combined with DNA-Barcode Sequencing.

02-02-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Investigation of sex and gender differences in oncology gains momentum: ESMO announces the launch of a Gender Medicine Task Force.

01-02-2022

Clinical genitourinary cancer

Symptomatic Skeletal Events and the Use of Bone Health Agents in a Real-World Treated Metastatic Castration Resistant Prostate Cancer Population: Results From the CAPRI-Study in the Netherlands.

01-02-2022

Cancer discovery

Improving the Affordability of Anticancer Medicines Demands Evidence-Based Policy Solutions.

01-02-2022

European journal of cancer (Oxford, England : 1990)

Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma: a retrospective multicentre analysis.

01-02-2022

Journal of pharmaceutical sciences

Population Pharmacokinetic Modelling to Support the Evaluation of Preclinical Pharmacokinetic Experiments with Lorlatinib.

01-02-2022

Abdominal radiology (New York)

Differences in the distribution of peritoneal metastases in right- versus left-sided colon cancer on MRI.

01-02-2022

JCO clinical cancer informatics

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

01-02-2022

Clinical pharmacokinetics

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.

01-02-2022

Breast cancer research and treatment

Prognosis of pregnancy-associated breast cancer: inferior outcome in patients diagnosed during second and third gestational trimesters and lactation.

01-02-2022

The Journal of biological chemistry

Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity.

01-02-2022

Health expectations : an international journal of public participation in health care and health policy

Development of a patient decision aid for patients with breast cancer who consider immediate breast reconstruction after mastectomy.

01-02-2022

Biopreservation and biobanking

Barriers and Facilitators for Implementing a National Guideline to Foster the Responsible Use of Residual Biospecimens and Data in Health Research.

01-02-2022

Scientific reports

Layer thickness prediction and tissue classification in two-layered tissue structures using diffuse reflectance spectroscopy.

01-02-2022

European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery

Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma: a one-year prospective evaluation.

01-02-2022

Current opinion in immunology

Safety switches for adoptive cell therapy.

01-02-2022

British journal of clinical pharmacology

Hyperhydration with cisplatin does not influence pemetrexed exposure.

01-02-2022

Journal of the European Academy of Dermatology and Venereology : JEADV

Survival of stage IV melanoma in Belgium and the Netherlands.

01-02-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Urethral and bladder dose-effect relations for late genitourinary toxicity following external beam radiotherapy for prostate cancer in the FLAME trial.

01-02-2022

Breast (Edinburgh, Scotland)

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study.

01-02-2022

Current opinion in cell biology

Lamina-associated domains: Tethers and looseners.

01-02-2022

Annals of oncology : official journal of the European Society for Medical Oncology

Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006.

01-02-2022

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Seeing the whole picture: Added value of MRI for extraperitoneal findings in CRS-HIPEC candidates.

01-02-2022

Nature cancer

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

01-02-2022

The Lancet. Oncology

Harmonising patient-access programmes: the Dutch DRUG Access Protocol platform.

01-02-2022

ESMO open

The impact of COVID-19 on oncology professionals-one year on: lessons learned from the ESMO Resilience Task Force survey series.

01-02-2022

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Oncology team perspectives on distress screening: a multisite study of a well-established use of patient-reported outcomes for clinical assessment.

01-02-2022

Prostate cancer and prostatic diseases

Integrated analysis of pain, health-related quality of life, and analgesic use in patients with metastatic castration-resistant prostate cancer treated with Radium-223.

01-02-2022

Cancer research

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture.

01-02-2022

Clinical pharmacology and therapeutics

Effects of the Moderate CYP3A4 Inhibitor Erythromycin on the Pharmacokinetics of Palbociclib: A Randomized Crossover Trial in Patients With Breast Cancer.

01-02-2022

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Technical feasibility and clinical evaluation of 4D-MRI guided liver SBRT on the MR-linac.

01-02-2022

Cancer reports (Hoboken, N.J.)

Unexpected toxicity of CDK4/6 inhibitor palbociclib and radiotherapy.

01-02-2022

Cancers

Development of a Disease-Specific Health-Related Quality of Life Questionnaire (DTF-QoL) for Patients with Desmoid-Type Fibromatosis.

29-01-2022

Frontiers in oncology

Twenty Years On: RECIST as a Biomarker of Response in Solid Tumours an EORTC Imaging Group - ESOI Joint Paper.

28-01-2022

Cancers

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy in Children with Cancer: A Systematic Review and Meta-Analysis.

26-01-2022

Frontiers in immunology

Tandem Substitutions in Somatic Hypermutation.

25-01-2022

Protocol: A Multiplexed Reporter Assay to Study Effects of Chromatin Context on DNA Double-Strand Break Repair.

Physical Activity Is Associated with Improved Overall Survival among Patients with Metastatic Colorectal Cancer.

[Clinical efficiency research with expensive drugs: doing more with less investment].

Association of Neutrophil-to-Lymphocyte Ratio with Efficacy of First-Line Avelumab plus Axitinib vs. Sunitinib in Patients with Advanced Renal Cell Carcinoma Enrolled in the Phase 3 JAVELIN Renal 101 Trial.

Combining Hepatic Percutaneous Perfusion with Ipilimumab plus Nivolumab in advanced uveal melanoma (CHOPIN): study protocol for a phase Ib/randomized phase II trial.

Molecular, Immunological, and Clinical Features Associated With Lymphoid Neogenesis in Muscle Invasive Bladder Cancer.

Cognitive adverse effects of chemotherapy and immunotherapy: are interventions within reach?

A large-scale organoid-based screening platform to advance drug repurposing in pancreatic cancer.

A Mediator-cohesin axis controls heterochromatin domain formation.

Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis.

Image quality of dual-energy cone-beam CT with total nuclear variation regularization.

Pregnancy-associated breast cancer: the influence of gestational age.

Unexpected gene activation following CRISPR-Cas9-mediated genome editing.

Genome-Wide Mapping and Microscopy Visualization of Protein-DNA Interactions by pA-DamID.

Epi-Decoder: Decoding the Local Proteome of a Genomic Locus by Massive Parallel Chromatin Immunoprecipitation Combined with DNA-Barcode Sequencing.

Investigation of sex and gender differences in oncology gains momentum: ESMO announces the launch of a Gender Medicine Task Force.

Symptomatic Skeletal Events and the Use of Bone Health Agents in a Real-World Treated Metastatic Castration Resistant Prostate Cancer Population: Results From the CAPRI-Study in the Netherlands.

Improving the Affordability of Anticancer Medicines Demands Evidence-Based Policy Solutions.

Chemotherapy after immune checkpoint inhibitor failure in metastatic melanoma: a retrospective multicentre analysis.

Population Pharmacokinetic Modelling to Support the Evaluation of Preclinical Pharmacokinetic Experiments with Lorlatinib.

Differences in the distribution of peritoneal metastases in right- versus left-sided colon cancer on MRI.

Genome Nexus: A Comprehensive Resource for the Annotation and Interpretation of Genomic Variants in Cancer.

Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.

Prognosis of pregnancy-associated breast cancer: inferior outcome in patients diagnosed during second and third gestational trimesters and lactation.

Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity.

Development of a patient decision aid for patients with breast cancer who consider immediate breast reconstruction after mastectomy.

Barriers and Facilitators for Implementing a National Guideline to Foster the Responsible Use of Residual Biospecimens and Data in Health Research.

Layer thickness prediction and tissue classification in two-layered tissue structures using diffuse reflectance spectroscopy.

Dysphagia, trismus and speech impairment following radiation-based treatment for advanced stage oropharyngeal carcinoma: a one-year prospective evaluation.

Safety switches for adoptive cell therapy.

Hyperhydration with cisplatin does not influence pemetrexed exposure.

Survival of stage IV melanoma in Belgium and the Netherlands.

Urethral and bladder dose-effect relations for late genitourinary toxicity following external beam radiotherapy for prostate cancer in the FLAME trial.

Effects of chemotherapy on contralateral breast cancer risk in BRCA1 and BRCA2 mutation carriers: A nationwide cohort study.

Lamina-associated domains: Tethers and looseners.

Antitumor activity of ipilimumab or BRAF ± MEK inhibition after pembrolizumab treatment in patients with advanced melanoma: analysis from KEYNOTE-006.

Seeing the whole picture: Added value of MRI for extraperitoneal findings in CRS-HIPEC candidates.

The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Harmonising patient-access programmes: the Dutch DRUG Access Protocol platform.

The impact of COVID-19 on oncology professionals-one year on: lessons learned from the ESMO Resilience Task Force survey series.

Oncology team perspectives on distress screening: a multisite study of a well-established use of patient-reported outcomes for clinical assessment.

Integrated analysis of pain, health-related quality of life, and analgesic use in patients with metastatic castration-resistant prostate cancer treated with Radium-223.

A Microfluidic Cancer-on-Chip Platform Predicts Drug Response Using Organotypic Tumor Slice Culture.

Effects of the Moderate CYP3A4 Inhibitor Erythromycin on the Pharmacokinetics of Palbociclib: A Randomized Crossover Trial in Patients With Breast Cancer.

Technical feasibility and clinical evaluation of 4D-MRI guided liver SBRT on the MR-linac.

Unexpected toxicity of CDK4/6 inhibitor palbociclib and radiotherapy.

Development of a Disease-Specific Health-Related Quality of Life Questionnaire (DTF-QoL) for Patients with Desmoid-Type Fibromatosis.

Twenty Years On: RECIST as a Biomarker of Response in Solid Tumours an EORTC Imaging Group - ESOI Joint Paper.

Pharmacogenomics of Vincristine-Induced Peripheral Neuropathy in Children with Cancer: A Systematic Review and Meta-Analysis.

Tandem Substitutions in Somatic Hypermutation.

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