Publications

European urology

Atezolizumab Versus Chemotherapy in Patients with Platinum-treated Locally Advanced or Metastatic Urothelial Carcinoma: A Long-term Overall Survival and Safety Update from the Phase 3 IMvigor211 Clinical Trial.

01-07-2021

Medical image analysis

Deep learning reconstruction of digital breast tomosynthesis images for accurate breast density and patient-specific radiation dose estimation.

01-07-2021

Journal of the National Cancer Institute

Performance of Breast Cancer Polygenic Risk Scores in 760 Female CHEK2 Germline Mutation Carriers.

01-07-2021

American journal of obstetrics and gynecology

Oral contraceptive use and ovarian cancer risk for BRCA1/2 mutation carriers: an international cohort study.

01-07-2021

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

The dynamics and prognostic value of FDG PET-metrics in weekly monitoring of (chemo)radiotherapy for NSCLC.

01-07-2021

Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland

The evaluation of follow-up strategies of watch-and-wait patients with a complete response after neoadjuvant therapy in rectal cancer.

01-07-2021

Trends in molecular medicine

Studying PAR-Dependent Chromatin Remodeling to Tackle PARPi Resistance.

01-07-2021

American journal of human genetics

Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element.

01-07-2021

Cancer medicine

Worse capecitabine treatment outcome in patients with a low skeletal muscle mass is not explained by altered pharmacokinetics.

01-07-2021

Molecular oncology

Epigenetic and transcriptional analysis reveals a core transcriptional program conserved in clonal prostate cancer metastases.

01-07-2021

Nature cell biology

Publisher Correction: Elongation factor ELOF1 drives transcription-coupled repair and prevents genome instability.

01-07-2021

The British journal of radiology

Prognostic value of breast MRI characteristics before and during neoadjuvant endocrine therapy in patients with ER+/HER2- breast cancer.

01-07-2021

Radiation research

Cellular Radiosensitivity of Soft Tissue Sarcoma.

01-07-2021

Annals of oncology : official journal of the European Society for Medical Oncology

Delayed immune-related adverse events with anti-PD-1-based immunotherapy in melanoma.

01-07-2021

Journal for immunotherapy of cancer

Clinical and immunologic implications of COVID-19 in patients with melanoma and renal cell carcinoma receiving immune checkpoint inhibitors.

01-07-2021

Nature

EGFR activation limits the response of liver cancer to lenvatinib.

01-07-2021

Scientific reports

A kinome-centered CRISPR-Cas9 screen identifies activated BRAF to modulate enzalutamide resistance with potential therapeutic implications in BRAF-mutated prostate cancer.

01-07-2021

JAMA oncology

Three-Year Follow-up of Neoadjuvant Chemotherapy With or Without Anthracyclines in the Presence of Dual ERBB2 Blockade in Patients With ERBB2-Positive Breast Cancer: A Secondary Analysis of the TRAIN-2 Randomized, Phase 3 Trial.

01-07-2021

European journal of cancer (Oxford, England : 1990)

The role of local therapy in the treatment of solitary melanoma progression on immune checkpoint inhibition: A multicentre retrospective analysis.

01-07-2021

European urology focus

Third-line Life-prolonging Drug Treatment in a Real-world Metastatic Castration-resistant Prostate Cancer Population: Results from the Dutch Castration-resistant Prostate Cancer Registry.

01-07-2021

Seminars in cancer biology

Artificial intelligence for breast cancer detection in mammography and digital breast tomosynthesis: State of the art.

01-07-2021

EBioMedicine

It takes two to tango, and the right music: Synergistic drug combinations with cell-cycle phase-dependent sensitivities.

01-07-2021

Nature medicine

An ex vivo tumor fragment platform to dissect response to PD-1 blockade in cancer.

01-07-2021

Journal of translational medicine

Perspectives in Melanoma: meeting report from the Melanoma Bridge (December 3rd-5th, 2020, Italy).

30-06-2021

Cell reports

Identification of presented SARS-CoV-2 HLA class I and HLA class II peptides using HLA peptidomics.

29-06-2021

Cancers

The Evaluation of Health-Related Quality of Life Issues Experienced by Patients with Desmoid-Type Fibromatosis (The QUALIFIED Study)-A Protocol for an International Cohort Study.

22-06-2021

Cancers

Response Prediction and Evaluation Using PET in Patients with Solid Tumors Treated with Immunotherapy.

21-06-2021

Scientific reports

Epigenetics Identifier screens reveal regulators of chromatin acylation and limited specificity of acylation antibodies.

17-06-2021

Cells

TRIMming Down Hormone-Driven Cancers: The Biological Impact of TRIM Proteins on Tumor Development, Progression and Prognostication.

16-06-2021

International journal of cancer

A Phase I dose-escalation study of two cycles carboplatin-olaparib followed by olaparib monotherapy in patients with advanced cancer.

15-06-2021

Cellular and molecular gastroenterology and hepatology

Early Life Antibiotics Influence In Vivo and In Vitro Mouse Intestinal Epithelium Maturation and Functioning.

09-06-2021

Nature communications

Oncogenic BRAF, unrestrained by TGFβ-receptor signalling, drives right-sided colonic tumorigenesis.

08-06-2021

Cancers

Toxicity, Response and Survival in Older Patients with Metastatic Melanoma Treated with Checkpoint Inhibitors.

05-06-2021

EMBO reports

Loss of enteric neuronal Ndrg4 promotes colorectal cancer via increased release of Nid1 and Fbln2.

04-06-2021

Clinical pharmacology in drug development

A Phase 1 Dose-Escalation Study of Low-Dose Metronomic Treatment With Novel Oral Paclitaxel Formulations in Combination With Ritonavir in Patients With Advanced Solid Tumors.

01-06-2021

The Journal of urology

Reply by Authors.

01-06-2021

Journal of the National Cancer Institute

Long-Term Risk of Ovarian Cancer and Borderline Tumors After Assisted Reproductive Technology.

01-06-2021

JAMA surgery

Axillary Pathologic Complete Response After Neoadjuvant Systemic Therapy by Breast Cancer Subtype in Patients With Initially Clinically Node-Positive Disease: A Systematic Review and Meta-analysis.

01-06-2021

The pharmacogenomics journal

Investigating the influence of relevant pharmacogenetic variants on the pharmacokinetics and pharmacodynamics of orally administered docetaxel combined with ritonavir.

01-06-2021

Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology

Transtympanic Sodium Thiosulfate for Prevention of Cisplatin-Induced Ototoxicity: A Randomized Clinical Trial.

01-06-2021

The Journal of urology

Intraoperative Strategies to Reduce Catheter-Related Bladder Discomfort in the Early Postoperative Period after Robot-Assisted Radical Prostatectomy.

01-06-2021

The Journal of allergy and clinical immunology

Defective neutrophil development and specific granule deficiency caused by a homozygous splice-site mutation in SMARCD2.

01-06-2021

Cardiovascular and interventional radiology

CT-Based Radiomics Analysis Before Thermal Ablation to Predict Local Tumor Progression for Colorectal Liver Metastases.

01-06-2021

Current opinion in cell biology

On the choreography of genome folding: A grand pas de deux of cohesin and CTCF.

01-06-2021

The Lancet. Oncology

Enfortumab vedotin after PD-1 or PD-L1 inhibitors in cisplatin-ineligible patients with advanced urothelial carcinoma (EV‑201): a multicentre, single-arm, phase 2 trial.

01-06-2021

Expert review of pharmacoeconomics & outcomes research

Early technology assessment of using whole genome sequencing in personalized oncology.

01-06-2021

Immuno-oncology technology

Integrated functional and spatial profiling of tumour immune responses induced by immunotherapy: the iPROFILER platform.

01-06-2021

Expert review of pharmacoeconomics & outcomes research

Micro-costing diagnostics in oncology: from single-gene testing to whole- genome sequencing.

01-06-2021

The Lancet. Oncology

Ipilimumab alone or ipilimumab plus anti-PD-1 therapy in patients with metastatic melanoma resistant to anti-PD-(L)1 monotherapy: a multicentre, retrospective, cohort study.

01-06-2021

European urology oncology

Toxicity and Surgical Complication Rates of Neoadjuvant Atezolizumab in Patients with Muscle-invasive Bladder Cancer Undergoing Radical Cystectomy: Updated Safety Results from the ABACUS Trial.

01-06-2021