Publications

Pharmacological research

Daraxonrasib (RMC-6236) pharmacokinetics: impact of transporters and drug-metabolizing enzymes on a first-in-class pan-RAS molecular glue.

01-07-2026

Journal of cancer survivorship : research and practice

Patient-reported outcomes in cancer survivorship: insights from two decades of population-based PROFILES registry research.

01-06-2026

European urology oncology

Update of the EORTC Health-related Quality of Life Modules for Bladder Cancer: Phase 1-2 of the Development Process.

26-05-2026

Breast (Edinburgh, Scotland)

Towards patient-centered research in pregnancy-associated breast cancer: creating a science agenda through a priority-setting-partnership.

15-05-2026

European journal of cancer (Oxford, England : 1990)

BRAF^V600E-mutated central nervous system tumors benefit from treatment with dabrafenib plus trametinib: Results from the Drug Rediscovery Protocol.

02-05-2026

FEBS open bio

Optimizing photoactivation of PA-mCherry for optical pooled CRISPR screens.

01-05-2026

Clinical cancer research : an official journal of the American Association for Cancer Research

plasmaCHORD: A Machine Learning Approach to Distinguish Clonal Hematopoiesis-Derived Variants in Liquid Biopsies from Patients with Solid Tumors.

01-05-2026

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Human epididymis protein 4 and risk of malignancy index as risk assessment tools in the decision for referral to an oncology center in patients with an ovarian mass: a cost-effectiveness analysis from a Dutch health care perspective.

22-04-2026

Clinical cancer research : an official journal of the American Association for Cancer Research

Transcriptomic insights into lobular breast cancer biology and patient outcomes: analysis of the MINDACT clinical trial.

17-04-2026

International journal for quality in health care : journal of the International Society for Quality in Health Care

The role of surgical margins as outcome metrics in a quality assurance program for robot-assisted radical prostatectomy.

13-04-2026

Psycho-oncology

Understanding Physical Activity in Patients With Metastatic Breast Cancer: An Analysis Rooted in the Theory of Planned Behaviour.

01-04-2026

Psycho-oncology

Managing Cancer and Living Meaningfully (CALM) for Patients With Metastatic Cancer and Treatment Response.

01-04-2026

European journal of cancer (Oxford, England : 1990)

Safety and feasibility of S-1 after capecitabine-induced toxicity in the adjuvant treatment of colon cancer patients: A population-based real-world study.

26-03-2026

International journal of computer assisted radiology and surgery

Machine learning-based treatment outcome prediction in head and neck cancer using integrated noninvasive diagnostics.

01-03-2026

The Lancet. Oncology

Percutaneous hepatic perfusion combined with ipilimumab and nivolumab for metastatic uveal melanoma (CHOPIN): a single-centre, open-label, randomised, phase 2 trial.

01-03-2026

Cell reports. Medicine

Liver metastases dampen IL18-driven γδ T cell activity and immunotherapy responsiveness in colorectal cancer.

17-02-2026

Journal of experimental & clinical cancer research : CR

Tertiary lymphoid structures in the era of cancer therapy.

11-02-2026

Breast (Edinburgh, Scotland)

Trends in local, regional and contralateral breast tumor recurrence within five years after diagnosis in the Netherlands: a population-based study including 121347 patients.

01-02-2026

European urology oncology

Novel Molecular Biomarkers to Guide Treatment Decision-making in Metastatic Urothelial Cancer-A Patient Cohort Analysis.

01-02-2026

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

ESMO-ESTRO consensus statements on the safety of combining radiotherapy with CDK4/6, HER2, PARP, or mTOR inhibitors.

01-02-2026

Oncogene

MDC1 counteracts replication fork reversal and mediates chemosensitivity in BRCA1/2-deficient tumors.

01-02-2026

Clinical pharmacokinetics

Population Pharmacokinetics of Total and Protein-Unbound Prednisolone in Children with Immune-Mediated and Systemic Inflammatory Diseases.

01-02-2026

Journal of cancer survivorship : research and practice

Eight-year follow-up of patient-reported outcomes in patients with breast cancer participating in exercise studies during chemotherapy.

01-02-2026

Cancer research

Chemotherapy-Treated Breast Cancer Cells Activate the WNT Signaling Pathway to Enter a Diapause-Like Early Persister State.

16-01-2026

Cancer discovery

Microbial Metabolic Pathways Guide Response to Immune Checkpoint Blockade Therapy.

12-01-2026

bioRxiv : the preprint server for biology

Functional characterization of a multi-cancer risk locus on chromosome band 2q33.1 near CASP8.

06-01-2026

ESMO open

Added value of tumor-stroma ratio to postsurgery circulating tumor DNA and pTN stage in risk stratification of patients with stage III colon cancer treated with adjuvant chemotherapy.

01-01-2026

The British journal of surgery

Health-related quality of life of patients undergoing active surveillance versus standard surgery for oesophageal cancer (SANO trial).

24-12-2025

Journal of cancer survivorship : research and practice

Health-related conditions among long-term cancer survivors diagnosed in adolescence and young adulthood (AYA): results of the SURVAYA study.

01-12-2025

Therapeutic drug monitoring

Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs: Achievements, Experiences, Challenges, and the Path Forward.

01-12-2025

Cell

Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1.

26-11-2025

Frontiers in oncology

Perforator mapping for head and neck reconstructive surgery: a novel personalized approach using magnetic resonance angiography based 3D models and 3D-printing.

16-10-2025

ESMO open

Minimum standards of specialist adolescent and young adult (AYA) cancer care units: recommendations and implementation roadmap.

01-10-2025

European radiology

Detection rates for prostate cancer using PI-RADS 2.1 upgrading rules in transition zone lesions align with risk assessment categories: a systematic review and meta-analysis.

01-10-2025

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

Changes in bone marrow fat fraction and immune cell counts in women with cervical cancer treated with primary chemoradiotherapy.

01-10-2025

Annals of oncology : official journal of the European Society for Medical Oncology

Health-related quality of life of patients with metastatic melanoma treated with tumor-infiltrating lymphocytes compared with ipilimumab in a randomized phase III trial.

01-10-2025

Key

Communications medicine

Clinical, pathological and molecular characteristics of patients with disease recurrence despite pathologic response to neoadjuvant ipilimumab plus nivolumab in stage III melanoma.

30-09-2025

iScience

A 3D genome compendium of breast cancer progression.

19-09-2025

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene

18-09-2025

Key

Nature medicine

Publisher Correction: Personalized, autologous neoantigen-specific T cell therapy in metastatic melanoma: a phase 1 trial.

01-09-2025

Annals of surgery

Association of Lateral Pelvic Lymph Nodes with Disease Recurrence and Organ Preservation in Patients with Distal Rectal Adenocarcinoma Treated with Total Neoadjuvant Therapy.

01-08-2025

Clinical pharmacology and therapeutics

Implementing Pre-Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects.

01-08-2025

Protein science : a publication of the Protein Society

DSSP 4: FAIR annotation of protein secondary structure.

01-08-2025

ESMO open

Exploratory subgroup analyses of EV-302: a phase III global study to evaluate enfortumab vedotin in combination with pembrolizumab versus chemotherapy in previously untreated locally advanced or metastatic urothelial carcinoma.

01-08-2025

The British journal of radiology

Imaging of cancer of unknown primary: a systematic literature review of the past, present, and future.

01-08-2025

Nature communications

USP1/UAF1 targets polyubiquitinated PCNA with an exo-cleavage mechanism that can temporarily enrich for monoubiquitinated PCNA.

30-07-2025

Nature communications

Intestinal tuft cell subtypes represent successive stages of maturation driven by crypt-villus signaling gradients.

22-07-2025

Science (New York, N.Y.)

Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression.

03-07-2025

NPJ digital medicine

H&E to IHC virtual staining methods in breast cancer: an overview and benchmarking.

02-07-2025

International journal of radiation oncology, biology, physics

Quality of Life and Toxicity in Patients With Pancreatic Ductal Adenocarcinoma Treated With Online Adaptive Stereotactic Magnetic Resonance Guided Radiation Therapy.

01-07-2025