Banner Publications MH200828 N141

Publications

Results found: 473

Showing results: 1 - 50

Nature

The Drug Rediscovery protocol facilitates the expanded use of existing anticancer drugs.

01-10-2019
Key
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Quantitative analysis of DNDI-6174 using UPLC-MS/MS: A preclinical target site pharmacokinetic study.

01-08-2025
Contemporary clinical trials communications

Pharmacokinetic boosting of olaparib: Study protocol of a multicentre, open-label, randomised, non-inferiority trial (PROACTIVE-B).

01-06-2025
Cancer reports (Hoboken, N.J.)

Imatinib Desensitization After a Type IV Hypersensitivity Reaction in a Gastrointestinal Stromal Tumor Patient-A Case Report.

01-06-2025
Oncology and therapy

Phase I Study of Sorafenib Combined with Gemcitabine and Carboplatin in Patients with Advanced Solid Tumors.

01-06-2025
Therapeutic drug monitoring

Stabilization of Abiraterone in Human Plasma Using the Esterase Inhibitor Bis(4-nitrophenyl) Phosphate: A Short Communication.

28-05-2025
Clinical pharmacology and therapeutics

Folinic Acid Prophylaxis and Dose Adjustments Enable Safe Treatment with Pemetrexed in Patients with Renal Impairment.

27-05-2025
Blood advances

Improved survival with model-based dosing of antithymocyte globulin in pediatric hematopoietic cell transplantation.

13-05-2025
Clinical pharmacology and therapeutics

Implementing Pre-Emptive Pharmacogenetics: Impact of Early Pharmacogenetic Screening in a Pediatric Oncology Cohort of 1,151 Subjects.

07-05-2025
European journal of cancer (Oxford, England : 1990)

Added prognostic value of circulating tumor cell numbers in CSF of patients with leptomeningeal metastasis from epithelial tumors.

02-05-2025
Biomedical chromatography : BMC

Advancing Therapeutic Drug Monitoring for Oral Targeted Anticancer Drugs: From Hospital-Based Towards Home-Sampling.

01-05-2025
British journal of cancer

Feasibility and efficacy of therapeutic drug monitoring of abiraterone in metastatic castration resistant prostate cancer patients.

01-04-2025
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer

Sex and Common Germline Variants Affect the Toxicity Profile and Pharmacokinetics of Alectinib: A Nationwide Cohort Study in Patients With ALK-Positive NSCLC.

01-04-2025
ESMO open

Palbociclib exposure in relation to efficacy and toxicity in patients with advanced breast cancer.

01-03-2025
Drug discovery today

The feasibility of using real world data as external control arms in oncology trials.

01-03-2025
Clinical pharmacokinetics

Population Pharmacokinetics of Cobicistat and its Effect on the Pharmacokinetics of the Anticancer Drug Olaparib.

01-03-2025
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

An ultra-sensitive liquid chromatography tandem mass spectrometry method for the simultaneous quantification of 2H6-alectinib and alectinib in human plasma to support a microtracer food-effect trial.

01-03-2025
Therapeutic drug monitoring

Clinical Application of Volumetric Absorptive Microsampling for Therapeutic Drug Monitoring of Oral Targeted Anticancer Drugs.

25-02-2025
Bone marrow transplantation

Evaluation of standard fludarabine dosing and corresponding exposures in infants and young children undergoing hematopoietic cell transplantation.

01-02-2025
Breast cancer research and treatment

Treatment sequences and survival outcomes in advanced HR + HER2- breast cancer patients: a real-world cohort.

01-02-2025
British journal of clinical pharmacology

Exploring the contribution of genetic variants to high sunitinib exposure in patients with cancer.

01-02-2025
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Bioanalysis of protein-unbound prednisolone in serum using equilibrium dialysis followed by liquid chromatography-tandem mass spectrometry.

01-02-2025
Cancer chemotherapy and pharmacology

Pharmacokinetic exposure and treatment outcomes of lenvatinib in patients with renal cell carcinoma and differentiated thyroid carcinoma.

17-01-2025
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.

01-01-2025
The Journal of infectious diseases

Disease-Specific Differences in Pharmacokinetics of Paromomycin and Miltefosine Between Post-Kala-Azar Dermal Leishmaniasis and Visceral Leishmaniasis Patients in Eastern Africa.

16-12-2024
Clinical pharmacokinetics

A Population Pharmacokinetic Study to Evaluate Doxorubicin Exposure Across All Age Groups.

01-12-2024
Haematologica

IKZF1 gene deletions drive resistance to cytarabine in B-cell precursor acute lymphoblastic leukemia.

01-12-2024
PloS one

Platinum retention in plasma, urine, and normal colonic mucosa in cisplatin-treated testicular cancer survivors.

14-11-2024
Drug metabolism and disposition: the biological fate of chemicals

Early Prediction and Impact Assessment of CYP3A4-Related Drug-Drug Interactions for Small-Molecule Anticancer Drugs Using Human-CYP3A4-Transgenic Mouse Models.

16-10-2024
Clinical cancer research : an official journal of the American Association for Cancer Research

Maximizing Treatment Opportunities: Assessing Protocol Waivers' Impact on Safety and Outcome in the Drug Rediscovery Protocol.

03-09-2024
Clinical pharmacology and therapeutics

Therapeutic Drug Monitoring of Oral Oncology Drugs: Finding the Right Nails.

01-09-2024
British journal of cancer

Reasons for non-feasibility of therapeutic drug monitoring of oral targeted therapies in oncology - an analysis of the closed cohorts of a multicentre prospective study.

01-09-2024
Cancer chemotherapy and pharmacology

A joint model of longitudinal pharmacokinetic and time-to-event data to study exposure-response relationships: a proof-of-concept study with alectinib.

01-09-2024
Pediatric blood & cancer

Vincristine exposure in Kenyan children with cancer: CHAPATI feasibility study.

01-09-2024
Clinical pharmacokinetics

Pharmacokinetics and Pharmacodynamics of Systemic Corticosteroids in Autoimmune and Inflammatory Diseases: A Review of Current Evidence.

01-09-2024
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners

Prolonged in-use physicochemical and biological stability of nivolumab and pembrolizumab diluted in saline infusion bags and in partially used medication vials.

30-08-2024
Journal of pharmaceutical and biomedical analysis

ELISA assay for the quantification of ipilimumab in human serum, plasma, milk, and cerebrospinal fluid.

01-08-2024
Clinical cancer research : an official journal of the American Association for Cancer Research

A Proof-of-Concept Study of Sequential Treatment with the HDAC Inhibitor Vorinostat following BRAF and MEK Inhibitors in BRAFV600-Mutated Melanoma.

01-08-2024
Journal of pharmaceutical and biomedical analysis

Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood.

01-08-2024
Clinical pharmacokinetics

Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease.

01-08-2024
Therapeutic drug monitoring

Analytical Validation of a Volumetric Absorptive Microsampling Method for Therapeutic Drug Monitoring of the Oral Targeted Anticancer Agents, Abiraterone, Alectinib, Cabozantinib, Imatinib, Olaparib, and Sunitinib, and Metabolites.

01-08-2024
Clinical pharmacokinetics

Evaluating the Clinical Impact and Feasibility of Therapeutic Drug Monitoring of Pazopanib in a Real-World Soft-Tissue Sarcoma Cohort.

01-07-2024
Clinical pharmacokinetics

Population Pharmacokinetics of Inotuzumab Ozogamicin in Pediatric Relapsed/Refractory B-Cell Precursor Acute Lymphoblastic Leukemia: Results of Study ITCC-059.

01-07-2024
European journal of drug metabolism and pharmacokinetics

The Use of Microdosing for In vivo Phenotyping of Cytochrome P450 Enzymes: Where Do We Stand? A Narrative Review.

01-07-2024
The Journal of antimicrobial chemotherapy

Skin pharmacokinetics of miltefosine in the treatment of post-kala-azar dermal leishmaniasis in South Asia.

01-07-2024
Cancer chemotherapy and pharmacology

Impact of bariatric surgery on oral anticancer drugs: an analysis of real-world data.

01-07-2024
Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Use of Sodium Thiosulfate as an Otoprotectant in Patients With Cancer Treated With Platinum Compounds: A Review of the Literature.

20-06-2024
Journal of pharmaceutical and biomedical analysis

A multiplex UPLC-MS/MS method for the quantification of three PD-L1 checkpoint inhibitors, atezolizumab, avelumab, and durvalumab, in human serum.

15-06-2024
ESMO open

Sunitinib for the treatment of metastatic gastrointestinal stromal tumors: the effect of TDM-guided dose optimization on clinical outcomes.

01-06-2024
Therapeutic drug monitoring

Tocilizumab Dose Tapering Based on a Model-Based Algorithm is Feasible in Clinical Practice: A Short Communication.

01-06-2024

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