Publications

Nederlands tijdschrift voor geneeskunde

[Trends and variation in breast conserving surgery in the southeast and east of the Netherlands over the period 1990-2002].

27-08-2005

Cold Spring Harbor symposia on quantitative biology

Functional identification of cancer-relevant genes through large-scale RNA interference screens in mammalian cells.

25-08-2005

Cold Spring Harbor symposia on quantitative biology

Emerging roles of Polycomb silencing in X-inactivation and stem cell maintenance.

25-08-2005

Cancer research

The neurotrophic receptor TrkB in anoikis resistance and metastasis: a perspective.

15-08-2005

Nature

BRAFE600-associated senescence-like cell cycle arrest of human naevi.

04-08-2005

Journal of immunology (Baltimore, Md. : 1950)

During viral infection of the respiratory tract, CD27, 4-1BB, and OX40 collectively determine formation of CD8+ memory T cells and their capacity for secondary expansion.

01-08-2005

Molecular and cellular biology

p53-Dependent regulation of Cdc6 protein stability controls cellular proliferation.

01-08-2005

European journal of cancer (Oxford, England : 1990)

Effective palliation by low dose local radiotherapy for recurrent and/or chemotherapy refractory non-follicular lymphoma patients.

01-08-2005

Investigational new drugs

Human metabolism of [(14)C]indisulam following i.v. infusion in cancer patients.

01-08-2005

Investigational new drugs

Tumor and normal tissue pharmacokinetics of perifosine, an oral anti-cancer alkylphospholipid.

01-08-2005

Cell cycle (Georgetown, Tex.)

Re-evaluating the role of Frat in Wnt-signal transduction.

01-08-2005

Anti-cancer drugs

Compatibility and stability of Imexon in infusion devices and its in vitro biocompatibility.

01-08-2005

Current opinion in immunology

MHC multimer technology: current status and future prospects.

01-08-2005

Nature medicine

A rapid and potent DNA vaccination strategy defined by in vivo monitoring of antigen expression.

01-08-2005

Analytical and bioanalytical chemistry

Determination of oxaliplatin in human plasma and plasma ultrafiltrate by graphite-furnace atomic-absorption spectrometry.

01-08-2005

International journal of radiation oncology, biology, physics

Thymidine analogues to assess microperfusion in human tumors.

15-07-2005

The Journal of biological chemistry

Crystal structure of acetylcholine-binding protein from Bulinus truncatus reveals the conserved structural scaffold and sites of variation in nicotinic acetylcholine receptors.

15-07-2005

Journal of pharmaceutical and biomedical analysis

LC-UV method development and validation for the investigational anticancer agent imexon and identification of its degradation products.

15-07-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Optimal locoregional treatment in gastric cancer.

10-07-2005

Rapid communications in mass spectrometry : RCM

Quantitative analysis of the farnesyl transferase inhibitor lonafarnib (Sarasartrade mark, SCH66336) in human plasma using high-performance liquid chromatography coupled with tandem mass spectrometry.

05-07-2005

Nature structural & molecular biology

Crystal structure of nicotinic acetylcholine receptor homolog AChBP in complex with an alpha-conotoxin PnIA variant.

01-07-2005

Head & neck

Hypoxia in head and neck cancer: how much, how important?

01-07-2005

Drug metabolism and disposition: the biological fate of chemicals

Midazolam and cyclosporin a metabolism in transgenic mice with liver-specific expression of human CYP3A4.

01-07-2005

European journal of cancer (Oxford, England : 1990)

Standardised FDG uptake: a prognostic factor for inoperable non-small cell lung cancer.

01-07-2005

International journal of radiation oncology, biology, physics

Pulmonary function changes after radiotherapy in non-small-cell lung cancer patients with long-term disease-free survival.

01-07-2005

Cancer immunology, immunotherapy : CII

A phase-II study of pegylated interferon alfa-2b for patients with metastatic renal cell carcinoma and removal of the primary tumor.

01-07-2005

Genome biology

Histone modifications: from genome-wide maps to functional insights.

18-06-2005

Cell

Stem cells for lung cancer?

17-06-2005

Cell

A genetic screen identifies PITX1 as a suppressor of RAS activity and tumorigenicity.

17-06-2005

Genes & development

Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.

15-06-2005

The Journal of biological chemistry

Modeling and experimental validation of the binary complex of the plectin actin-binding domain and the first pair of fibronectin type III (FNIII) domains of the beta4 integrin.

10-06-2005

The Journal of biological chemistry

Inhibition of autotaxin by lysophosphatidic acid and sphingosine 1-phosphate.

03-06-2005

Current opinion in immunology

CD27 and CD70 in T cell and B cell activation.

01-06-2005

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

The prognostic significance of axillary lymph-node micrometastases in breast cancer patients.

01-06-2005

Current opinion in microbiology

Presenting antigen presentation in living cells using biophysical techniques.

01-06-2005

Nature genetics

Mapping of genetic and epigenetic regulatory networks using microarrays.

01-06-2005

European journal of cancer (Oxford, England : 1990)

Increased risk of breast cancer development after diagnosis of salivary gland tumour.

01-06-2005

Investigational new drugs

Semi-physiological model describing the hematological toxicity of the anti-cancer agent indisulam.

01-06-2005

Therapeutic drug monitoring

Sparse sampling design for therapeutic drug monitoring of sequentially administered cyclophosphamide, thiotepa, and carboplatin (CTC).

01-06-2005

Biomedical chromatography : BMC

Quantitative analysis of docetaxel in human plasma using liquid chromatography coupled with tandem mass spectrometry.

01-06-2005

Experimental lung research

Lung tumor location and lymphocyte infiltration in mice are genetically determined.

01-06-2005

Cancer cell

A functional approach to questions about life, death, and phosphorylation.

01-06-2005

Proceedings of the National Academy of Sciences of the United States of America

Stable X chromosome inactivation involves the PRC1 Polycomb complex and requires histone MACROH2A1 and the CULLIN3/SPOP ubiquitin E3 ligase.

24-05-2005

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Changes in gene expression associated with response to neoadjuvant chemotherapy in breast cancer.

20-05-2005

Proceedings of the National Academy of Sciences of the United States of America

Mice lacking multidrug resistance protein 3 show altered morphine pharmacokinetics and morphine-6-glucuronide antinociception.

17-05-2005

American journal of epidemiology

Validity of self-reported causes of subfertility.

15-05-2005

The Journal of cell biology

Integrins control motile strategy through a Rho-cofilin pathway.

09-05-2005

The EMBO journal

PIP2 signaling in lipid domains: a critical re-evaluation.

04-05-2005

Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology

Whole-genome views of chromatin structure.

04-05-2005

Journal of pharmaceutical sciences

Pharmaceutical development of a lyophilised dosage form for the investigational anticancer agent Imexon using dimethyl sulfoxide as solubilising and stabilising agent.

01-05-2005