Publications

Nature genetics

Characterization of induced cohesin loop extrusion trajectories in living cells.

16-10-2025

Nucleic acids research

Coordinated control of genome-nuclear lamina interactions by topoisomerase 2B and lamin B receptor.

23-09-2025

iScience

A 3D genome compendium of breast cancer progression.

19-09-2025

Science (New York, N.Y.)

Functional maps of a genomic locus reveal confinement of an enhancer by its target gene.

18-09-2025

Nature structural & molecular biology

Interactions between the genome and the nuclear lamina are multivalent and cooperative.

01-09-2025

Developmental cell

Identifying cross-lineage dependencies of cell-type-specific regulators in mouse gastruloids.

21-07-2025

Cancer cell

Understanding and reversing mammary tumor-driven reprogramming of myelopoiesis to reduce metastatic spread.

14-07-2025

Nucleic acids research

Extrusion fountains are restricted by WAPL-dependent cohesin release and CTCF barriers.

20-06-2025

PloS one

Stem cell culture conditions affect in vitro differentiation potential and mouse gastruloid formation.

27-03-2025

bioRxiv : the preprint server for biology

Pervasive and programmed nucleosome distortion patterns on single mammalian chromatin fibers.

22-01-2025

Molecular cell

ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF.

02-01-2025

Cell

Macrophage-mediated myelin recycling fuels brain cancer malignancy.

19-09-2024

Current opinion in genetics & development

Attraction and disruption: how loop extrusion and compartmentalisation shape the nuclear genome.

01-06-2024

Nature communications

SMARCB1 loss activates patient-specific distal oncogenic enhancers in malignant rhabdoid tumors.

01-12-2023

Cell reports

Perturbations in 3D genome organization can promote acquired drug resistance.

31-10-2023

The EMBO journal

Pioneer activity distinguishes activating from non-activating SOX2 binding sites.

16-10-2023

Molecular cell

Lifting the curtain on loop extrusion barriers: Single-molecule insights into cohesin stalling.

17-08-2023

Nature reviews. Genetics

New insights into genome folding by loop extrusion from inducible degron technologies.

01-02-2023

EMBO reports

Dynamic chromosomal interactions and control of heterochromatin positioning by Ki-67.

06-12-2022

Nature structural & molecular biology

Distinct roles for CKM-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction.

01-10-2022

Genome biology

CTCF and cohesin promote focal detachment of DNA from the nuclear lamina.

01-09-2022

Methods in molecular biology (Clifton, N.J.)

Acute Protein Depletion Strategies to Functionally Dissect the 3D Genome.

23-07-2022

Nature structural & molecular biology

The cohesin acetylation cycle controls chromatin loop length through a PDS5A brake mechanism.

01-06-2022

Nature communications

A Mediator-cohesin axis controls heterochromatin domain formation.

08-02-2022

EMBO reports

Unexpected gene activation following CRISPR-Cas9-mediated genome editing.

03-02-2022

Nature communications

Glucocorticoid receptor triggers a reversible drug-tolerant dormancy state with acquired therapeutic vulnerabilities in lung cancer.

16-07-2021

NAR genomics and bioinformatics

Hi-C analyses with GENOVA: a case study with cohesin variants.

01-06-2021

Science (New York, N.Y.)

3D genomics across the tree of life reveals condensin II as a determinant of architecture type.

28-05-2021

EMBO reports

Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.

03-02-2021

Nature genetics

WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation.

01-01-2021

Proceedings of the National Academy of Sciences of the United States of America

The histone methyltransferase DOT1L prevents antigen-independent differentiation and safeguards epigenetic identity of CD8⁺ T cells.

25-08-2020

Journal of molecular biology

TADs as the Caller Calls Them.

07-02-2020

Nature

The structural basis for cohesin-CTCF-anchored loops.

01-02-2020

Molecular cell

Distinct Roles for Condensin's Two ATPase Sites in Chromosome Condensation.

05-12-2019

Trends in genetics : TIG

Gene Regulation Knows Its Boundaries.

01-12-2019

Nature cell biology

A transient absence of SMC-mediated loops after mitosis.

01-11-2019

Nucleic acids research

A CRISPR-Cas9 screen identifies essential CTCF anchor sites for estrogen receptor-driven breast cancer cell proliferation.

10-10-2019

Cell

The ChAHP Complex Counteracts Chromatin Looping at CTCF Sites that Emerged from SINE Expansions in Mouse.

05-09-2019

Nature genetics

High-throughput identification of human SNPs affecting regulatory element activity.

01-07-2019

Nature genetics

The bipartite TAD organization of the X-inactivation center ensures opposing developmental regulation of Tsix and Xist.

01-06-2019

Essays in biochemistry

CTCF: a Swiss-army knife for genome organization and transcription regulation.

23-04-2019

Current opinion in genetics & development

Developing landscapes: genome architecture during early embryogenesis.

01-04-2019

Nature communications

A natural WNT signaling variant potently synergizes with Cdkn2ab loss in skin carcinogenesis.

29-03-2019

Nucleic acids research

peakC: a flexible, non-parametric peak calling package for 4C and Capture-C data.

06-09-2018

Nature genetics

Enhancer hubs and loop collisions identified from single-allele topologies.

01-08-2018

Cell reports

Systemic Loss and Gain of Chromatin Architecture throughout Zebrafish Development.

03-07-2018

Nucleic acids research

LncRNA-OIS1 regulates DPP4 activation to modulate senescence induced by RAS.

04-05-2018

American journal of human genetics

Sensitive Monogenic Noninvasive Prenatal Diagnosis by Targeted Haplotyping.

07-09-2017

Nature structural & molecular biology

Capturing heterogeneity: single-cell structures of the 3D genome.

04-05-2017

Cell

The Cohesin Release Factor WAPL Restricts Chromatin Loop Extension.

04-05-2017